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The map label for this gene is gap [H]

Identifier: 239618380

GI number: 239618380

Start: 2150171

End: 2151166

Strand: Direct

Name: gap [H]

Synonym: Kole_2020

Alternate gene names: 239618380

Gene position: 2150171-2151166 (Clockwise)

Preceding gene: 239618379

Following gene: 239618381

Centisome position: 93.4

GC content: 43.37

Gene sequence:

>996_bases
ATGAAAGTCGCGATTAACGGTTTTGGAAGAATTGGGAGATTGGTGTTCAGAGAGATGGTAAAGCGCGGAAACTTTGATGT
TGTAGCAATCAACGACCTTACAGACGCAAAGACACTGGCACACCTGCTCAAATACGATAGTGTTCACGGCAAATTTGATG
GAACAGTGGAAGCAAAAGATTCAGCGATAGTAGTCAATGGAAAAGAGATCAAGATCTTTGCTGAAAAGAATCCCGGTAAT
CTTCCCTGGAAGGATCTTGGAGTTGACATTGTTATTGAATCAACGGGTGTCTTTAGAAACAAAGAAAAGGCCATGCCACA
TATCGAAGCCGGTGCCAAAAAAGTCATTATAACAGCTCCCGCTAAGGGCGAAGTTGATGCTACAGTGGTTCTTGGTGTCA
ACGACGAAGTTCTGAAGCCTGAACATCAGGTGATCTCGAATGCCTCCTGTACAACGAATTCCATTGCACCGGTTATAAAG
GTTCTTCATGAAAAATTCAAGGTTTTGAGTGGATTCCTCACAACGGTTCATGCATATACGAACGATCAGAGAATTCTTGA
TCTTCCGCATAAGGATCTCAGAAGAGCAAGAGCTGCCGCTGCAAACACAATTCCAACAACAACTGGCGCTGCCAAAGCCG
TTGGAGTAGTTATTCCCGAACTCAAGGGGAAACTCGATGGTATGGCTATCAGGGTTCCTGTTCCTGATGGTTCAATAACT
GACCTTACGGTTGTTGTTGAGAAAGAAACAACTGTTGATGAAGTTAACGCCGTTATGAAAGAAGCAAGTGAAACCTATCT
GAAGGGTATCCTTGGATATAACGAAGAACCTATTGTGAGTGGTGATATTGTTGGAACTTCATTCTCTGGAATCTTCGACG
CAACACTTACAATGGTCAAAGGAAATCTGGTAAAAATCGCATCCTGGTACGATAACGAATACGGTTACAGCTGCAGAGTT
GTTGATCTGGTCGAAAAGCTCGAGGCAATGCTTTGA

Upstream 100 bases:

>100_bases
AAGTGGGAAAGAAAAGAGAAGAAGAATCAGGAAAAATAAGTTCTATGCTGAATTTACCGGATAAAATGCTCTAACAAGCT
TATTTTAGGAGGTGCTAAAG

Downstream 100 bases:

>100_bases
GCTTAAATATAAACCGGGGCCCCTGAATGCTGGGGCCCTTTTTGACAGATTTACGTTAAGGGAGGGATAGAAATGCTGAA
GAAACTTACAGTAAAGGATG

Product: glyceraldehyde-3-phosphate dehydrogenase, type I

Products: NA

Alternate protein names: GAPDH [H]

Number of amino acids: Translated: 331; Mature: 331

Protein sequence:

>331_residues
MKVAINGFGRIGRLVFREMVKRGNFDVVAINDLTDAKTLAHLLKYDSVHGKFDGTVEAKDSAIVVNGKEIKIFAEKNPGN
LPWKDLGVDIVIESTGVFRNKEKAMPHIEAGAKKVIITAPAKGEVDATVVLGVNDEVLKPEHQVISNASCTTNSIAPVIK
VLHEKFKVLSGFLTTVHAYTNDQRILDLPHKDLRRARAAAANTIPTTTGAAKAVGVVIPELKGKLDGMAIRVPVPDGSIT
DLTVVVEKETTVDEVNAVMKEASETYLKGILGYNEEPIVSGDIVGTSFSGIFDATLTMVKGNLVKIASWYDNEYGYSCRV
VDLVEKLEAML

Sequences:

>Translated_331_residues
MKVAINGFGRIGRLVFREMVKRGNFDVVAINDLTDAKTLAHLLKYDSVHGKFDGTVEAKDSAIVVNGKEIKIFAEKNPGN
LPWKDLGVDIVIESTGVFRNKEKAMPHIEAGAKKVIITAPAKGEVDATVVLGVNDEVLKPEHQVISNASCTTNSIAPVIK
VLHEKFKVLSGFLTTVHAYTNDQRILDLPHKDLRRARAAAANTIPTTTGAAKAVGVVIPELKGKLDGMAIRVPVPDGSIT
DLTVVVEKETTVDEVNAVMKEASETYLKGILGYNEEPIVSGDIVGTSFSGIFDATLTMVKGNLVKIASWYDNEYGYSCRV
VDLVEKLEAML
>Mature_331_residues
MKVAINGFGRIGRLVFREMVKRGNFDVVAINDLTDAKTLAHLLKYDSVHGKFDGTVEAKDSAIVVNGKEIKIFAEKNPGN
LPWKDLGVDIVIESTGVFRNKEKAMPHIEAGAKKVIITAPAKGEVDATVVLGVNDEVLKPEHQVISNASCTTNSIAPVIK
VLHEKFKVLSGFLTTVHAYTNDQRILDLPHKDLRRARAAAANTIPTTTGAAKAVGVVIPELKGKLDGMAIRVPVPDGSIT
DLTVVVEKETTVDEVNAVMKEASETYLKGILGYNEEPIVSGDIVGTSFSGIFDATLTMVKGNLVKIASWYDNEYGYSCRV
VDLVEKLEAML

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=333, Percent_Identity=49.8498498498498, Blast_Score=318, Evalue=5e-87,
Organism=Homo sapiens, GI7657116, Length=332, Percent_Identity=46.6867469879518, Blast_Score=300, Evalue=1e-81,
Organism=Escherichia coli, GI1788079, Length=330, Percent_Identity=51.2121212121212, Blast_Score=340, Evalue=5e-95,
Organism=Escherichia coli, GI1789295, Length=326, Percent_Identity=42.9447852760736, Blast_Score=286, Evalue=2e-78,
Organism=Caenorhabditis elegans, GI17534677, Length=332, Percent_Identity=50.3012048192771, Blast_Score=302, Evalue=2e-82,
Organism=Caenorhabditis elegans, GI17534679, Length=332, Percent_Identity=50.3012048192771, Blast_Score=301, Evalue=4e-82,
Organism=Caenorhabditis elegans, GI32566163, Length=337, Percent_Identity=48.3679525222552, Blast_Score=294, Evalue=5e-80,
Organism=Caenorhabditis elegans, GI17568413, Length=337, Percent_Identity=48.3679525222552, Blast_Score=294, Evalue=5e-80,
Organism=Saccharomyces cerevisiae, GI6322468, Length=330, Percent_Identity=52.4242424242424, Blast_Score=341, Evalue=1e-94,
Organism=Saccharomyces cerevisiae, GI6321631, Length=330, Percent_Identity=52.4242424242424, Blast_Score=340, Evalue=3e-94,
Organism=Saccharomyces cerevisiae, GI6322409, Length=328, Percent_Identity=49.390243902439, Blast_Score=333, Evalue=2e-92,
Organism=Drosophila melanogaster, GI17933600, Length=332, Percent_Identity=49.0963855421687, Blast_Score=319, Evalue=2e-87,
Organism=Drosophila melanogaster, GI18110149, Length=332, Percent_Identity=49.0963855421687, Blast_Score=319, Evalue=2e-87,
Organism=Drosophila melanogaster, GI85725000, Length=332, Percent_Identity=49.6987951807229, Blast_Score=318, Evalue=4e-87,
Organism=Drosophila melanogaster, GI22023983, Length=332, Percent_Identity=49.6987951807229, Blast_Score=318, Evalue=4e-87,
Organism=Drosophila melanogaster, GI19922412, Length=326, Percent_Identity=48.4662576687117, Blast_Score=312, Evalue=2e-85,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35799; Mature: 35799

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVAINGFGRIGRLVFREMVKRGNFDVVAINDLTDAKTLAHLLKYDSVHGKFDGTVEAKD
CEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCEEECCC
SAIVVNGKEIKIFAEKNPGNLPWKDLGVDIVIESTGVFRNKEKAMPHIEAGAKKVIITAP
CEEEEECCEEEEEEECCCCCCCHHHCCEEEEEECCCCCCCHHHCCCCCCCCCCEEEEECC
AKGEVDATVVLGVNDEVLKPEHQVISNASCTTNSIAPVIKVLHEKFKVLSGFLTTVHAYT
CCCCCCEEEEEECCCHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEC
NDQRILDLPHKDLRRARAAAANTIPTTTGAAKAVGVVIPELKGKLDGMAIRVPVPDGSIT
CCCEEEECCHHHHHHHHHHHCCCCCCCCCCHHHHEEEEHHHCCCCCCEEEEEECCCCCCE
DLTVVVEKETTVDEVNAVMKEASETYLKGILGYNEEPIVSGDIVGTSFSGIFDATLTMVK
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCEECCCCCHHHHHHHHHHC
GNLVKIASWYDNEYGYSCRVVDLVEKLEAML
CCEEEEEEEECCCCCCEEHHHHHHHHHHHCC
>Mature Secondary Structure
MKVAINGFGRIGRLVFREMVKRGNFDVVAINDLTDAKTLAHLLKYDSVHGKFDGTVEAKD
CEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCEEECCC
SAIVVNGKEIKIFAEKNPGNLPWKDLGVDIVIESTGVFRNKEKAMPHIEAGAKKVIITAP
CEEEEECCEEEEEEECCCCCCCHHHCCEEEEEECCCCCCCHHHCCCCCCCCCCEEEEECC
AKGEVDATVVLGVNDEVLKPEHQVISNASCTTNSIAPVIKVLHEKFKVLSGFLTTVHAYT
CCCCCCEEEEEECCCHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEC
NDQRILDLPHKDLRRARAAAANTIPTTTGAAKAVGVVIPELKGKLDGMAIRVPVPDGSIT
CCCEEEECCHHHHHHHHHHHCCCCCCCCCCHHHHEEEEHHHCCCCCCEEEEEECCCCCCE
DLTVVVEKETTVDEVNAVMKEASETYLKGILGYNEEPIVSGDIVGTSFSGIFDATLTMVK
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCEECCCCCHHHHHHHHHHC
GNLVKIASWYDNEYGYSCRVVDLVEKLEAML
CCEEEEEEEECCCCCCEEHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8508805; 10360571; 2401296; 7877172 [H]