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The map label for this gene is rpe [H]

Identifier: 239618304

GI number: 239618304

Start: 2060597

End: 2061244

Strand: Reverse

Name: rpe [H]

Synonym: Kole_1941

Alternate gene names: 239618304

Gene position: 2061244-2060597 (Counterclockwise)

Preceding gene: 239618305

Following gene: 239618303

Centisome position: 89.54

GC content: 44.6

Gene sequence:

>648_bases
ATGGCTCTGGTTTCACCTTCCATACTGGCGGCGGATTTCGCCAACCTTTCTGCTGAAATAGACAAGATCAAAGATGCCGA
TTTCATTCACGTGGACGTCATGGACGGGGTTTTCGTCCCCAACATAACCTTTGGGACACCTATAATGGAAGCCCTTAATA
AGCTGGACACACCACCATTGGATGTTCATCTCATGATTGACAATCCATCACAGTACATAGAGAAATTCGCCAATCTCGGT
GCCTCAATACTCGCGGTTCATATAGAAGCTGAAAGGCATCTTCACAGACTTGTCGATCGAATTAAAAGCCTCGACGTTGA
AGCTTTTGTCGCAGTTAATCCCCATACACCCGTATCTGCGCTTGAAGAGATCATACAATTTGTCGATGGTGTTCTTATCA
TGACAGTTAACCCTGGCTTCACGGGCCAAAGCTTCATTCCCGAAACAGCTCAAAAAATTGCCAAGCTTGATCACTTAAGG
AAGGAAAAAGGTCTGAATTTCAGGATCGCTGTTGACGGTGGAATAAACCTGAAAAATGCACAGACAGTCGTCGATTACGG
GGCAGATATACTCATCATGGGAGCCGCTATCTTCAGATCCGAAAATCCTGCAGAGGTTATACAAAAAGTCAAGGAGTTGA
AAAAATGA

Upstream 100 bases:

>100_bases
TGAGACCGGTGATATTCCCATGAGTCGTTATGAAAGTTACCTTAAGATGTATAATGAGCTTTCCGAAAGAAAAAAAGGAC
GCAAAGGAGGCAGGAGATAA

Downstream 100 bases:

>100_bases
AAGTTTATCTTGTTTCCGGGAATACCCATAAATTGCTGGAAATACAAAAAATAGCCCCAGAAGGCGTTGAGATAGAGAGT
ATAACATCTCTTGATGTGTC

Product: ribulose-phosphate 3-epimerase

Products: NA

Alternate protein names: Pentose-5-phosphate 3-epimerase; PPE; R5P3E [H]

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MALVSPSILAADFANLSAEIDKIKDADFIHVDVMDGVFVPNITFGTPIMEALNKLDTPPLDVHLMIDNPSQYIEKFANLG
ASILAVHIEAERHLHRLVDRIKSLDVEAFVAVNPHTPVSALEEIIQFVDGVLIMTVNPGFTGQSFIPETAQKIAKLDHLR
KEKGLNFRIAVDGGINLKNAQTVVDYGADILIMGAAIFRSENPAEVIQKVKELKK

Sequences:

>Translated_215_residues
MALVSPSILAADFANLSAEIDKIKDADFIHVDVMDGVFVPNITFGTPIMEALNKLDTPPLDVHLMIDNPSQYIEKFANLG
ASILAVHIEAERHLHRLVDRIKSLDVEAFVAVNPHTPVSALEEIIQFVDGVLIMTVNPGFTGQSFIPETAQKIAKLDHLR
KEKGLNFRIAVDGGINLKNAQTVVDYGADILIMGAAIFRSENPAEVIQKVKELKK
>Mature_214_residues
ALVSPSILAADFANLSAEIDKIKDADFIHVDVMDGVFVPNITFGTPIMEALNKLDTPPLDVHLMIDNPSQYIEKFANLGA
SILAVHIEAERHLHRLVDRIKSLDVEAFVAVNPHTPVSALEEIIQFVDGVLIMTVNPGFTGQSFIPETAQKIAKLDHLRK
EKGLNFRIAVDGGINLKNAQTVVDYGADILIMGAAIFRSENPAEVIQKVKELKK

Specific function: Unknown

COG id: COG0036

COG function: function code G; Pentose-5-phosphate-3-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribulose-phosphate 3-epimerase family [H]

Homologues:

Organism=Homo sapiens, GI40385883, Length=214, Percent_Identity=36.9158878504673, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI219879828, Length=214, Percent_Identity=35.0467289719626, Blast_Score=135, Evalue=3e-32,
Organism=Homo sapiens, GI24307923, Length=164, Percent_Identity=29.8780487804878, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1789788, Length=217, Percent_Identity=40.0921658986175, Blast_Score=159, Evalue=1e-40,
Organism=Escherichia coli, GI1790523, Length=195, Percent_Identity=38.974358974359, Blast_Score=154, Evalue=3e-39,
Organism=Escherichia coli, GI1790754, Length=202, Percent_Identity=29.2079207920792, Blast_Score=95, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17552948, Length=216, Percent_Identity=36.5740740740741, Blast_Score=141, Evalue=3e-34,
Organism=Saccharomyces cerevisiae, GI6322341, Length=225, Percent_Identity=36.8888888888889, Blast_Score=151, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24586301, Length=215, Percent_Identity=37.6744186046512, Blast_Score=159, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000056
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00834 Ribul_P_3_epim [H]

EC number: =5.1.3.1 [H]

Molecular weight: Translated: 23574; Mature: 23442

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS01085 RIBUL_P_3_EPIMER_1 ; PS01086 RIBUL_P_3_EPIMER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVSPSILAADFANLSAEIDKIKDADFIHVDVMDGVFVPNITFGTPIMEALNKLDTPPL
CCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEECCCCCCCCHHHHHHHHCCCCCC
DVHLMIDNPSQYIEKFANLGASILAVHIEAERHLHRLVDRIKSLDVEAFVAVNPHTPVSA
EEEEEECCHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHH
LEEIIQFVDGVLIMTVNPGFTGQSFIPETAQKIAKLDHLRKEKGLNFRIAVDGGINLKNA
HHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
QTVVDYGADILIMGAAIFRSENPAEVIQKVKELKK
HHHHHCCCCEEEEHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
ALVSPSILAADFANLSAEIDKIKDADFIHVDVMDGVFVPNITFGTPIMEALNKLDTPPL
CCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCEECCCCCCCCHHHHHHHHCCCCCC
DVHLMIDNPSQYIEKFANLGASILAVHIEAERHLHRLVDRIKSLDVEAFVAVNPHTPVSA
EEEEEECCHHHHHHHHHCCCCEEEEEEEHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHH
LEEIIQFVDGVLIMTVNPGFTGQSFIPETAQKIAKLDHLRKEKGLNFRIAVDGGINLKNA
HHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCC
QTVVDYGADILIMGAAIFRSENPAEVIQKVKELKK
HHHHHCCCCEEEEHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231; 9298645 [H]