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The map label for this gene is yggV [C]

Identifier: 239618303

GI number: 239618303

Start: 2060007

End: 2060600

Strand: Reverse

Name: yggV [C]

Synonym: Kole_1940

Alternate gene names: 239618303

Gene position: 2060600-2060007 (Counterclockwise)

Preceding gene: 239618304

Following gene: 239618299

Centisome position: 89.51

GC content: 42.09

Gene sequence:

>594_bases
ATGAAAGTTTATCTTGTTTCCGGGAATACCCATAAATTGCTGGAAATACAAAAAATAGCCCCAGAAGGCGTTGAGATAGA
GAGTATAACATCTCTTGATGTGTCCTTAAACATCGATGAAAACGGAGACACCTTCATTCAAAACTCAATAAAAAAAGTTG
AAGCCTTTCGAAATTTGGGTGTTCCCCTTATAGCAGATGATTCCGGCCTCGAAATCGATGCGCTTGACGGTTTCCCTGGC
GTGCATTCTGCGCGTTTCATGGAAGAGCATTCTTACGAAGAGAAAATGCAAGCAATCCTCGAAAAACTTGCGAACGTCGA
AAACAGAACCGCACGTTTCCGATGCGCCGCAACCTTTTTTGATCCGAAAAATTTCATCCTCCTCGCAGCCGAAGGAACGG
TAGAGGGCACAATAGCCTTAGAAATAAGAGGCAACAAAGGTTTTGGATACGATCCTATATTCATTCCCGAAGGTTATAAG
AAAACCTTCGGCGAATTAGGGGAAGAAATAAAAAATCGAATAAGCCATCGTTCGAGGGCTTTCAAGAGACTCTTCGAACT
TCTTCACCTCTATATCTTGCATGAAAGAATATGA

Upstream 100 bases:

>100_bases
CAGTCGTCGATTACGGGGCAGATATACTCATCATGGGAGCCGCTATCTTCAGATCCGAAAATCCTGCAGAGGTTATACAA
AAAGTCAAGGAGTTGAAAAA

Downstream 100 bases:

>100_bases
TCAACCCCACGATCATCAGAATCACAGAAACCAGCTTTGCGGTTCTCAGCTCACCGACATAGAGGCTGTCAAGCCTCAAT
CCTTCTATGACGAATCTACC

Product: non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MKVYLVSGNTHKLLEIQKIAPEGVEIESITSLDVSLNIDENGDTFIQNSIKKVEAFRNLGVPLIADDSGLEIDALDGFPG
VHSARFMEEHSYEEKMQAILEKLANVENRTARFRCAATFFDPKNFILLAAEGTVEGTIALEIRGNKGFGYDPIFIPEGYK
KTFGELGEEIKNRISHRSRAFKRLFELLHLYILHERI

Sequences:

>Translated_197_residues
MKVYLVSGNTHKLLEIQKIAPEGVEIESITSLDVSLNIDENGDTFIQNSIKKVEAFRNLGVPLIADDSGLEIDALDGFPG
VHSARFMEEHSYEEKMQAILEKLANVENRTARFRCAATFFDPKNFILLAAEGTVEGTIALEIRGNKGFGYDPIFIPEGYK
KTFGELGEEIKNRISHRSRAFKRLFELLHLYILHERI
>Mature_197_residues
MKVYLVSGNTHKLLEIQKIAPEGVEIESITSLDVSLNIDENGDTFIQNSIKKVEAFRNLGVPLIADDSGLEIDALDGFPG
VHSARFMEEHSYEEKMQAILEKLANVENRTARFRCAATFFDPKNFILLAAEGTVEGTIALEIRGNKGFGYDPIFIPEGYK
KTFGELGEEIKNRISHRSRAFKRLFELLHLYILHERI

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=188, Percent_Identity=31.9148936170213, Blast_Score=81, Evalue=5e-16,
Organism=Homo sapiens, GI31657144, Length=141, Percent_Identity=35.4609929078014, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1789324, Length=196, Percent_Identity=39.2857142857143, Blast_Score=120, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17556833, Length=188, Percent_Identity=29.7872340425532, Blast_Score=87, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6322529, Length=199, Percent_Identity=29.6482412060301, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920712, Length=187, Percent_Identity=34.2245989304813, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22272; Mature: 22272

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVYLVSGNTHKLLEIQKIAPEGVEIESITSLDVSLNIDENGDTFIQNSIKKVEAFRNLG
CEEEEEECCCEEEEEEEECCCCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCC
VPLIADDSGLEIDALDGFPGVHSARFMEEHSYEEKMQAILEKLANVENRTARFRCAATFF
CEEEECCCCCEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEE
DPKNFILLAAEGTVEGTIALEIRGNKGFGYDPIFIPEGYKKTFGELGEEIKNRISHRSRA
CCCCEEEEEECCCCCEEEEEEEECCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHH
FKRLFELLHLYILHERI
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVYLVSGNTHKLLEIQKIAPEGVEIESITSLDVSLNIDENGDTFIQNSIKKVEAFRNLG
CEEEEEECCCEEEEEEEECCCCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHCC
VPLIADDSGLEIDALDGFPGVHSARFMEEHSYEEKMQAILEKLANVENRTARFRCAATFF
CEEEECCCCCEEEECCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEEEEE
DPKNFILLAAEGTVEGTIALEIRGNKGFGYDPIFIPEGYKKTFGELGEEIKNRISHRSRA
CCCCEEEEEECCCCCEEEEEEEECCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHH
FKRLFELLHLYILHERI
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]