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The map label for this gene is aspC [H]

Identifier: 239618290

GI number: 239618290

Start: 2048177

End: 2049340

Strand: Reverse

Name: aspC [H]

Synonym: Kole_1927

Alternate gene names: 239618290

Gene position: 2049340-2048177 (Counterclockwise)

Preceding gene: 239618291

Following gene: 239618288

Centisome position: 89.02

GC content: 41.84

Gene sequence:

>1164_bases
TTGAAATTTTCAAACTCCATTACCTCTGTTTCACCATCCGTTACCCTCGAATTCAATCAGAAAGCCCTCGAAATGCTTTC
AAAGGGTGAAGATGTGGTAAAGCTCACGGCTGGCGAGCCAGATTTTCCAACCCCTAAACCTATAATAGAAGCTGCCGTTG
AAGCCATGCGAGAAGGTAAAACCAAATACACCAACGCTTCTGGAATACCTCTTTTGAGAGAAAAAATCTCTGAAAAACTG
CGTGTGGAAAACCATCTGAATTATTCTCCAGACGAAATTATTGTAACCAACGGTGGAAAACAGGCTCTTTACAACACACT
TTCAGCAATACTGAACCCGGGAGACGAAGTGATTCTCTTTGCTCCTGCCTGGGTTAGTTATGGTGCACAGGTTAAAATGT
GCGGAGGAATTCCTATCTTTGTAGGGACAAAAATGGAAGATGATTTCTTGCCGAAAATCAAAGACATAGAAAAAGCGATT
TCGCCTCGCACCAGGGCTATGATTATAAATTCTCCAAACAACCCGACCGGAACAATGTATCCAGAGAGTCTTCTTACAGA
ACTGGCGAATCTTGCAAAATCCCAGGATATATTCGTCATTTCAGATGAAGTATACGAAAAACTTTCCTTCGATGAAAAGC
ACTTCAGTATCGCTTCTATCGAAGGAATGAAAGACCGTGCAGCAGTGATAAATGCTTTTTCAAAAGCCTATGCTATGACT
GGGTGGAGGATTGGTTATGTGGCTGCTCCACACTCCCTCGCAAAACAGATAGCTAAGATTCAGAGCCATCTTTCTTCCAA
TGTGAATACCATGACTCAATATGCCGCTGTAAAAGCTTTCGGGGTCGACATAAGTGAAATGCTTGAAGAATTCATAAAGA
GAAGGGAATACGTAGAAACTCGGTTGAAAAAAATAGGCGTGCCCTTCTCTCATCCTAAAGGAGCATTTTACTTTTTTATT
GACATAAGAGATTATTTGACTGAAACGTACCCGGACTCCCTGAGCTTCGCTATTGCCCTTCTTGAGAAAGCCAAAGTGGG
AATGATCCCCGGTAGCGCTTTCAACGCCGAAGGATTTATAAGGCTTTCTTATGCGAGCTCAATTGAAACACTGAAAAAAG
GGCTGGATAGGTTCGAAGGTTTTTTGAAAAAATCTGATAGATAA

Upstream 100 bases:

>100_bases
CAGGAGCAAGGCTCTTCAGGAAGGATAGCTTCAATGACGTTGTCCTTGTTATATTGGATACATTGAATAGAATGTAGCTC
AAAACCTGGAGGTGCCAAGA

Downstream 100 bases:

>100_bases
ATATTAAACCTATTTGTTCATCTTCCCATCCATCTGAGGCCCCATTTAAAATCTTCAGAAACAAATCTGACGCTGGAGAA
CTCTGATTTAGCCAATTGAT

Product: aminotransferase class I and II

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 387; Mature: 387

Protein sequence:

>387_residues
MKFSNSITSVSPSVTLEFNQKALEMLSKGEDVVKLTAGEPDFPTPKPIIEAAVEAMREGKTKYTNASGIPLLREKISEKL
RVENHLNYSPDEIIVTNGGKQALYNTLSAILNPGDEVILFAPAWVSYGAQVKMCGGIPIFVGTKMEDDFLPKIKDIEKAI
SPRTRAMIINSPNNPTGTMYPESLLTELANLAKSQDIFVISDEVYEKLSFDEKHFSIASIEGMKDRAAVINAFSKAYAMT
GWRIGYVAAPHSLAKQIAKIQSHLSSNVNTMTQYAAVKAFGVDISEMLEEFIKRREYVETRLKKIGVPFSHPKGAFYFFI
DIRDYLTETYPDSLSFAIALLEKAKVGMIPGSAFNAEGFIRLSYASSIETLKKGLDRFEGFLKKSDR

Sequences:

>Translated_387_residues
MKFSNSITSVSPSVTLEFNQKALEMLSKGEDVVKLTAGEPDFPTPKPIIEAAVEAMREGKTKYTNASGIPLLREKISEKL
RVENHLNYSPDEIIVTNGGKQALYNTLSAILNPGDEVILFAPAWVSYGAQVKMCGGIPIFVGTKMEDDFLPKIKDIEKAI
SPRTRAMIINSPNNPTGTMYPESLLTELANLAKSQDIFVISDEVYEKLSFDEKHFSIASIEGMKDRAAVINAFSKAYAMT
GWRIGYVAAPHSLAKQIAKIQSHLSSNVNTMTQYAAVKAFGVDISEMLEEFIKRREYVETRLKKIGVPFSHPKGAFYFFI
DIRDYLTETYPDSLSFAIALLEKAKVGMIPGSAFNAEGFIRLSYASSIETLKKGLDRFEGFLKKSDR
>Mature_387_residues
MKFSNSITSVSPSVTLEFNQKALEMLSKGEDVVKLTAGEPDFPTPKPIIEAAVEAMREGKTKYTNASGIPLLREKISEKL
RVENHLNYSPDEIIVTNGGKQALYNTLSAILNPGDEVILFAPAWVSYGAQVKMCGGIPIFVGTKMEDDFLPKIKDIEKAI
SPRTRAMIINSPNNPTGTMYPESLLTELANLAKSQDIFVISDEVYEKLSFDEKHFSIASIEGMKDRAAVINAFSKAYAMT
GWRIGYVAAPHSLAKQIAKIQSHLSSNVNTMTQYAAVKAFGVDISEMLEEFIKRREYVETRLKKIGVPFSHPKGAFYFFI
DIRDYLTETYPDSLSFAIALLEKAKVGMIPGSAFNAEGFIRLSYASSIETLKKGLDRFEGFLKKSDR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=414, Percent_Identity=28.5024154589372, Blast_Score=159, Evalue=6e-39,
Organism=Homo sapiens, GI56713256, Length=414, Percent_Identity=28.5024154589372, Blast_Score=158, Evalue=7e-39,
Organism=Homo sapiens, GI95147551, Length=324, Percent_Identity=27.4691358024691, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI169881279, Length=324, Percent_Identity=27.4691358024691, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI169881281, Length=230, Percent_Identity=25.6521739130435, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI187936925, Length=353, Percent_Identity=24.6458923512748, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI14211921, Length=353, Percent_Identity=24.6458923512748, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI149944424, Length=372, Percent_Identity=22.8494623655914, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI4507369, Length=380, Percent_Identity=21.8421052631579, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI7705897, Length=294, Percent_Identity=27.2108843537415, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI33469970, Length=294, Percent_Identity=27.2108843537415, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1786816, Length=367, Percent_Identity=29.700272479564, Blast_Score=181, Evalue=7e-47,
Organism=Escherichia coli, GI1788722, Length=356, Percent_Identity=31.1797752808989, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1788627, Length=385, Percent_Identity=27.5324675324675, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1790797, Length=365, Percent_Identity=24.6575342465753, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1787710, Length=311, Percent_Identity=23.1511254019293, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788332, Length=237, Percent_Identity=24.4725738396624, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71994476, Length=415, Percent_Identity=29.3975903614458, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI71994472, Length=415, Percent_Identity=29.3975903614458, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17567369, Length=419, Percent_Identity=27.6849642004773, Blast_Score=150, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI17567663, Length=376, Percent_Identity=22.8723404255319, Blast_Score=102, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322401, Length=394, Percent_Identity=24.8730964467005, Blast_Score=125, Evalue=8e-30,
Organism=Drosophila melanogaster, GI28573069, Length=404, Percent_Identity=26.7326732673267, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24646114, Length=404, Percent_Identity=26.7326732673267, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573067, Length=404, Percent_Identity=26.7326732673267, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI28573065, Length=404, Percent_Identity=26.7326732673267, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI18859735, Length=378, Percent_Identity=21.4285714285714, Blast_Score=80, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42947; Mature: 42947

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFSNSITSVSPSVTLEFNQKALEMLSKGEDVVKLTAGEPDFPTPKPIIEAAVEAMREGK
CCCCCCCCCCCCCEEEEECHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCC
TKYTNASGIPLLREKISEKLRVENHLNYSPDEIIVTNGGKQALYNTLSAILNPGDEVILF
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEE
APAWVSYGAQVKMCGGIPIFVGTKMEDDFLPKIKDIEKAISPRTRAMIINSPNNPTGTMY
ECHHHCCCCEEEEECCEEEEEECCCCCHHCCHHHHHHHHHCCCEEEEEEECCCCCCCCCC
PESLLTELANLAKSQDIFVISDEVYEKLSFDEKHFSIASIEGMKDRAAVINAFSKAYAMT
HHHHHHHHHHHHCCCCEEEECHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHC
GWRIGYVAAPHSLAKQIAKIQSHLSSNVNTMTQYAAVKAFGVDISEMLEEFIKRREYVET
CCEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RLKKIGVPFSHPKGAFYFFIDIRDYLTETYPDSLSFAIALLEKAKVGMIPGSAFNAEGFI
HHHHCCCCCCCCCCCEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEE
RLSYASSIETLKKGLDRFEGFLKKSDR
EEEHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKFSNSITSVSPSVTLEFNQKALEMLSKGEDVVKLTAGEPDFPTPKPIIEAAVEAMREGK
CCCCCCCCCCCCCEEEEECHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHCCC
TKYTNASGIPLLREKISEKLRVENHLNYSPDEIIVTNGGKQALYNTLSAILNPGDEVILF
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEE
APAWVSYGAQVKMCGGIPIFVGTKMEDDFLPKIKDIEKAISPRTRAMIINSPNNPTGTMY
ECHHHCCCCEEEEECCEEEEEECCCCCHHCCHHHHHHHHHCCCEEEEEEECCCCCCCCCC
PESLLTELANLAKSQDIFVISDEVYEKLSFDEKHFSIASIEGMKDRAAVINAFSKAYAMT
HHHHHHHHHHHHCCCCEEEECHHHHHHHCCCCHHEEEEECCCCHHHHHHHHHHHHHHHHC
GWRIGYVAAPHSLAKQIAKIQSHLSSNVNTMTQYAAVKAFGVDISEMLEEFIKRREYVET
CCEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RLKKIGVPFSHPKGAFYFFIDIRDYLTETYPDSLSFAIALLEKAKVGMIPGSAFNAEGFI
HHHHCCCCCCCCCCCEEEEEEHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEE
RLSYASSIETLKKGLDRFEGFLKKSDR
EEEHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]