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The map label for this gene is tal

Identifier: 239618235

GI number: 239618235

Start: 2008414

End: 2009070

Strand: Reverse

Name: tal

Synonym: Kole_1872

Alternate gene names: 239618235

Gene position: 2009070-2008414 (Counterclockwise)

Preceding gene: 239618236

Following gene: 239618234

Centisome position: 87.27

GC content: 43.99

Gene sequence:

>657_bases
ATGCGAATATTCCTGGACACCGCTAATATTGAAGAGATTAAGAAAGCTGTGGCCTGGGGAGTAATCGATGGAGTTACTAC
AAATCCAACATTGATAGCTCGCGAAAAAGCCCCTTTCACAGAGAGAATAAAAGAAATCTGCGAAACAGTGAAGGGCCCTG
TCAGTGCGGAGGTCGTTGCACTGGATTATGAAGGAATGGTGAAAGAAGCACGGGATCTTGCAATGCTCGATGAACACGTC
GTTATCAAAATTCCAATGACTCCTGAAGGAATCAAAGCGGTAAAAACCCTTTCATCTGAAGGAATTAAAACAAATGTTAC
TCTTGTTTTCAGTGCGGTTCAAGCTCTTCTGGCAGCAAAAGCGGGCGCAACGTATGTAAGCCCGTTTATCGGGCGTGTGG
ACGATATCTCCTCTGATGGCTTGAGGCTTGTTGAGGATATCGTTGCTATATTCTCAAATTATGGTTTTCAAACAAACGTT
CTCGCAGCGAGTATACGCCATCCGATGCACGTGCTGGAACTCGCTACAATCGGCGTAGACATTGTAACTATGCCCTTTAA
TGTTCTCGAAAAACTCTTTCATCACCCCCTAACTGACAAAGGAATTGAAAGGTTCTTAAATGACTGGGAAGAATACAGAA
AAGGTACAGGCCTTTGA

Upstream 100 bases:

>100_bases
TTCAACTCGTAGAAACAAAAAGCGAAGAAAACGTTGAAAACTAAAGATGGCTACCCGCGGTAGCCATCTTTTTTATCTGC
GTCATCCAAGGAGGTAAAAT

Downstream 100 bases:

>100_bases
TTTTTGAATAGAGGTGTGTTATATTTAATGCGAGGAAAGTTTGTACTTCCCCTCTTACTTGTTTTTCCCTTCGTAAAACT
GCACCAGTGTTAATTCATAA

Product: translaldolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MRIFLDTANIEEIKKAVAWGVIDGVTTNPTLIAREKAPFTERIKEICETVKGPVSAEVVALDYEGMVKEARDLAMLDEHV
VIKIPMTPEGIKAVKTLSSEGIKTNVTLVFSAVQALLAAKAGATYVSPFIGRVDDISSDGLRLVEDIVAIFSNYGFQTNV
LAASIRHPMHVLELATIGVDIVTMPFNVLEKLFHHPLTDKGIERFLNDWEEYRKGTGL

Sequences:

>Translated_218_residues
MRIFLDTANIEEIKKAVAWGVIDGVTTNPTLIAREKAPFTERIKEICETVKGPVSAEVVALDYEGMVKEARDLAMLDEHV
VIKIPMTPEGIKAVKTLSSEGIKTNVTLVFSAVQALLAAKAGATYVSPFIGRVDDISSDGLRLVEDIVAIFSNYGFQTNV
LAASIRHPMHVLELATIGVDIVTMPFNVLEKLFHHPLTDKGIERFLNDWEEYRKGTGL
>Mature_218_residues
MRIFLDTANIEEIKKAVAWGVIDGVTTNPTLIAREKAPFTERIKEICETVKGPVSAEVVALDYEGMVKEARDLAMLDEHV
VIKIPMTPEGIKAVKTLSSEGIKTNVTLVFSAVQALLAAKAGATYVSPFIGRVDDISSDGLRLVEDIVAIFSNYGFQTNV
LAASIRHPMHVLELATIGVDIVTMPFNVLEKLFHHPLTDKGIERFLNDWEEYRKGTGL

Specific function: Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway

COG id: COG0176

COG function: function code G; Transaldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transaldolase family. Type 3B subfamily

Homologues:

Organism=Homo sapiens, GI5803187, Length=174, Percent_Identity=32.7586206896552, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI87081788, Length=212, Percent_Identity=34.9056603773585, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790382, Length=211, Percent_Identity=37.914691943128, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1788807, Length=203, Percent_Identity=32.512315270936, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1786189, Length=237, Percent_Identity=30.379746835443, Blast_Score=83, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI25153750, Length=173, Percent_Identity=32.9479768786127, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321480, Length=237, Percent_Identity=32.0675105485232, Blast_Score=95, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323386, Length=202, Percent_Identity=34.6534653465347, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI45549185, Length=172, Percent_Identity=32.5581395348837, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TAL_KOSOT (C5CGH2)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002941557.1
- ProteinModelPortal:   C5CGH2
- GeneID:   7967794
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_1872
- ProtClustDB:   PRK01362
- GO:   GO:0005737
- HAMAP:   MF_00494
- InterPro:   IPR013785
- InterPro:   IPR001585
- InterPro:   IPR004731
- InterPro:   IPR022999
- InterPro:   IPR018225
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10683
- TIGRFAMs:   TIGR00875

Pfam domain/function: PF00923 Transaldolase

EC number: =2.2.1.2

Molecular weight: Translated: 23980; Mature: 23980

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS01054 TRANSALDOLASE_1; PS00958 TRANSALDOLASE_2

Important sites: ACT_SITE 83-83

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFLDTANIEEIKKAVAWGVIDGVTTNPTLIAREKAPFTERIKEICETVKGPVSAEVVA
CEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEE
LDYEGMVKEARDLAMLDEHVVIKIPMTPEGIKAVKTLSSEGIKTNVTLVFSAVQALLAAK
ECHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AGATYVSPFIGRVDDISSDGLRLVEDIVAIFSNYGFQTNVLAASIRHPMHVLELATIGVD
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHH
IVTMPFNVLEKLFHHPLTDKGIERFLNDWEEYRKGTGL
HEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRIFLDTANIEEIKKAVAWGVIDGVTTNPTLIAREKAPFTERIKEICETVKGPVSAEVVA
CEEEEECCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCEEEEE
LDYEGMVKEARDLAMLDEHVVIKIPMTPEGIKAVKTLSSEGIKTNVTLVFSAVQALLAAK
ECHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
AGATYVSPFIGRVDDISSDGLRLVEDIVAIFSNYGFQTNVLAASIRHPMHVLELATIGVD
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCHH
IVTMPFNVLEKLFHHPLTDKGIERFLNDWEEYRKGTGL
HEECCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA