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The map label for this gene is pyrK [H]

Identifier: 239618191

GI number: 239618191

Start: 1955363

End: 1956205

Strand: Direct

Name: pyrK [H]

Synonym: Kole_1827

Alternate gene names: 239618191

Gene position: 1955363-1956205 (Clockwise)

Preceding gene: 239618190

Following gene: 239618192

Centisome position: 84.94

GC content: 44.72

Gene sequence:

>843_bases
ATGGCGCACAGAATTCTCCGGAAAAGAAAGCTAGCCCCGGGGGTTTATGAATTCTGGATAGAACATGAACAGATTTCAAA
ATATGCTAAGCCGGGTCAATTTCTAATTATTCGATCGAATGAAAAAGGCGAGCGAATTCCTTTAACCATTGTGGAGGCTT
CAAAAAACGCTGTACGAGTCATAGTTAAATGCATAGGAAAATCCACCTACATGATGGCAATGATGAACGAAGGAGATGAA
TTTCTGGATGTTGTCGGCCCTCTCGGCAATCCAAGCGAAATAGATTACTATGGGCATGTAACTGTCATAGGTGGAGGTGT
CGGGATAGCTCCCCTTCTTCCTATAACGAGAGCTCTTAAGAAGGCAAAAAATCGGATAACAGCGATACTTGGGGCAGCAA
CGGCTGAGCAATTGATCCTGAAAGATGAGTTTGAAGAAACGGTGGATAATCTTATCCTTACGACGGATGATGGAACTTTT
GGTAAGAAAGGGCTCGTAACGGAGAGACTCGAAGAATTAATAGCTTCGGGTGACAAACCCGACATTATCTGGGCGATAGG
TCCTACGGTGATGATGAAGTTTGTTTCCCTTATCGCAGCGAGAGAAAATATTCTTTGCTGGGCTTCGCTTAATCCCATTA
TGGTCGATGGAACCGGAATGTGCGGAGCCTGCAGGGTGGAAGTTGACGGCCATATGAAGTTCGCGTGTGTAGATGGTCCG
GAATTTGATGGAAGGAAGGTCAACTGGAACGAATTGATAAAACGCCAGCATCAATACATGGAAGAAGAAAGAAAAGCGCT
TGAGGCTTTTAAGAAAAAGGCTGGTGATCTCTCATGGCTGTGA

Upstream 100 bases:

>100_bases
AATCCTGCGATGAAAAAATTTTAGGAGATTCTACGATGTTTTTTCAAAACCCTCCGGGGCTGCTATTATAGGAATGAGCC
CATAGAAAGGTGGGAAAAGT

Downstream 100 bases:

>100_bases
GCAGACCCAAGAAAGTTCCGATGCCTGAATTACCACCACACGAAAGAATAGTGTCTTTTAAAGAAGTTGCTTTAGGGTAC
ACAGAAGAGCAGGCTGTTGT

Product: oxidoreductase FAD/NAD(P)-binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MAHRILRKRKLAPGVYEFWIEHEQISKYAKPGQFLIIRSNEKGERIPLTIVEASKNAVRVIVKCIGKSTYMMAMMNEGDE
FLDVVGPLGNPSEIDYYGHVTVIGGGVGIAPLLPITRALKKAKNRITAILGAATAEQLILKDEFEETVDNLILTTDDGTF
GKKGLVTERLEELIASGDKPDIIWAIGPTVMMKFVSLIAARENILCWASLNPIMVDGTGMCGACRVEVDGHMKFACVDGP
EFDGRKVNWNELIKRQHQYMEEERKALEAFKKKAGDLSWL

Sequences:

>Translated_280_residues
MAHRILRKRKLAPGVYEFWIEHEQISKYAKPGQFLIIRSNEKGERIPLTIVEASKNAVRVIVKCIGKSTYMMAMMNEGDE
FLDVVGPLGNPSEIDYYGHVTVIGGGVGIAPLLPITRALKKAKNRITAILGAATAEQLILKDEFEETVDNLILTTDDGTF
GKKGLVTERLEELIASGDKPDIIWAIGPTVMMKFVSLIAARENILCWASLNPIMVDGTGMCGACRVEVDGHMKFACVDGP
EFDGRKVNWNELIKRQHQYMEEERKALEAFKKKAGDLSWL
>Mature_279_residues
AHRILRKRKLAPGVYEFWIEHEQISKYAKPGQFLIIRSNEKGERIPLTIVEASKNAVRVIVKCIGKSTYMMAMMNEGDEF
LDVVGPLGNPSEIDYYGHVTVIGGGVGIAPLLPITRALKKAKNRITAILGAATAEQLILKDEFEETVDNLILTTDDGTFG
KKGLVTERLEELIASGDKPDIIWAIGPTVMMKFVSLIAARENILCWASLNPIMVDGTGMCGACRVEVDGHMKFACVDGPE
FDGRKVNWNELIKRQHQYMEEERKALEAFKKKAGDLSWL

Specific function: Is responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the pyrD subunit to the ultimate electron acceptor NAD(+) [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 31180; Mature: 31049

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHRILRKRKLAPGVYEFWIEHEQISKYAKPGQFLIIRSNEKGERIPLTIVEASKNAVRV
CCHHHHHHHCCCCCHHHHHHCHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCHHHHH
IVKCIGKSTYMMAMMNEGDEFLDVVGPLGNPSEIDYYGHVTVIGGGVGIAPLLPITRALK
HHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHH
KAKNRITAILGAATAEQLILKDEFEETVDNLILTTDDGTFGKKGLVTERLEELIASGDKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCC
DIIWAIGPTVMMKFVSLIAARENILCWASLNPIMVDGTGMCGACRVEVDGHMKFACVDGP
CEEEEECHHHHHHHHHHHHHHCCEEEEEECCEEEEECCCCCCEEEEEECCCEEEEEECCC
EFDGRKVNWNELIKRQHQYMEEERKALEAFKKKAGDLSWL
CCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
AHRILRKRKLAPGVYEFWIEHEQISKYAKPGQFLIIRSNEKGERIPLTIVEASKNAVRV
CHHHHHHHCCCCCHHHHHHCHHHHHHHCCCCCEEEEECCCCCCCCCEEEEECCCHHHHH
IVKCIGKSTYMMAMMNEGDEFLDVVGPLGNPSEIDYYGHVTVIGGGVGIAPLLPITRALK
HHHHHCCCCEEEEEECCCHHHHHHHCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHH
KAKNRITAILGAATAEQLILKDEFEETVDNLILTTDDGTFGKKGLVTERLEELIASGDKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCC
DIIWAIGPTVMMKFVSLIAARENILCWASLNPIMVDGTGMCGACRVEVDGHMKFACVDGP
CEEEEECHHHHHHHHHHHHHHCCEEEEEECCEEEEECCCCCCEEEEEECCCEEEEEECCC
EFDGRKVNWNELIKRQHQYMEEERKALEAFKKKAGDLSWL
CCCCCEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]