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The map label for this gene is prsA [H]

Identifier: 239618053

GI number: 239618053

Start: 1813557

End: 1815407

Strand: Direct

Name: prsA [H]

Synonym: Kole_1682

Alternate gene names: 239618053

Gene position: 1813557-1815407 (Clockwise)

Preceding gene: 239618052

Following gene: 239618067

Centisome position: 78.78

GC content: 41.33

Gene sequence:

>1851_bases
GTGAAGAAATTCCTGATTATTTTGGTTGTATTTGTTTTAGGGGTATTGGGTTTTACCAACAGCATTATTGCCGAACTTAC
TGTTGATGGAACAATTACAGGGGTTCATGCTTTCCAGGTTGGATACGATGAGTACGAAAGTGCTCTTCAAGGGGCTCTGG
CGAATTACGAAAGCCAGGGACAGAGTATCGACAAGTATTTTGGAAAAGAATCGCTGCCAAGCGAGATACAGCTGGGATAT
AGTGTCCTGAAGGTTTTGCTTGATAGAAAGGTTATGGCCTTTTTTGCTATGGAGCAGGATGTATTTCCAGATGAGGCTCA
GGTTCAACAGATCACAGATGAGCTTGTTTCAAGATACATCTCGGATGAGACAACCAGAGCACAGCTTGAGATGTATTACG
GTTCTATAGAAAACTTTAGAAAGGTCGTTGAGGATATTGTGTTTGTGAGAACCCTTAGCCAGAATGTCTTCAATGCAATC
GTTCCGGATTATGATGCGAGTGCAACGGAATATTTTGAAAAAAATAAGACTGACATTAAGAATGAATACGAAAGTGTTAA
CGCAGCTCATATACTTGTTTCAACTGAAGCAAGCGCGATGGAGCTGAAAGAAAAGATACTTTTAGGGGAGCTTTCTTTTG
AAGAAGCAGCCAAAAGGTATTCTCTGGACCAATACTCAGCCCAGCAGGGAGGAAATATTGGAGAGTTGAAACATGGTACC
GTGATTTTAGAATTTGAAGAGGCAGCCTTCGCTGCCACTCCCGGTGAGATTGTAGGGCCGGTGAAAACCGATTACGGTTA
TCATCTTATAAAAGTGAACAGCAAGACCACTTTTGACTCATATGAAGATCTGAAGAATAGCAAGGCTTATGAGGACATAA
TGAGTCGGTTTGAGAATGAGGCCTTTCTTGGCTGGATAACAAAGTATAGACAGGATAAAAAGATACACTATATCATTTAC
GAAGAAGATCTGAAAACCTTTGGCGAACTGGCGAATCTGACCGATCCTGGGAAGTTCTATAACCGCATCGTTAATTCACT
GTTCGATGAAAACAACGAATTGAAAGCAGGGGTTCCCGGGATTATCGCCGCGTTTTATATACAAATGGCGGACGATGAGC
TCAAACAATATGAATCTCGTGAAGAAGCTTTCAAAACGATAATAGGAATTTGTGAGAGATTGCCGGAAGAGGAAAAGGGT
GTTGAGCATTTTTCCGAATTAAAGGATAAAGCTGCGGAAAACGAAAACGTTAAACAGCTCCTGGATTACGCTGAAATCCT
TGGAGTCGATTCGATTGAAAATGTGCACCTCAGGTTAGAGGAAATCAGGAATTACATGCGGGAAATCATGAATAAGGCTA
AAAAAGTGGCATGGTATCTTTACGACAAAGCTCCTGATTCAGAAAAACTTCTAGAATATCTTTATCGTTTCGATTCCGAT
AATCCTAAAGCCGTTTATCTGTACACGGAGAATTTTTACAAAAATCAGGTTCAGCCTGTTCTGGCGGATTCTGATATATT
TTCGAGCTACATAAATGCATACAAACAATACCTTGGTGAAAATGCTACGGAGACGCTTCTCGGTTACCTGATTAAGGGAT
TGGAAGGAAGGCTTGTTGAAAAAATCGTGGAAGACGAAAGTGTATCTGAAGATCTGAGGAAATCCGCGCTTGAGTTACTC
GTTGACGCCTATGAAAATGCATGCAATCTTCCACTGGATAATAGGTTGAAACTTCAGTATCTGGGAACCGAGAGAGATTA
TCTCCTGAAGCTTTCGGAATTAACTCCTGAGGCCACAGATGTTAAACAGTTGTTGGATGCTGTGGATGAGAGATTGAAGG
AGCTTCGGTAG

Upstream 100 bases:

>100_bases
GTAGAGGCATATTATGTAACAGGGAAAAAGTAGGGAATTTGTTGCTTCCAATCATGATAGTATTGTATGTAGGTTATTTA
TAACGGAAGGATGTGGTTTT

Downstream 100 bases:

>100_bases
TTTTTCCGCCAAAGAAAAAGCGCCCCAGATGGGGCGCTTTTTTAGCTTAAATTCAATTTGAATATATCGGAAGTTCCTTA
AAGAGGTTGAGAACATCGGT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 616; Mature: 616

Protein sequence:

>616_residues
MKKFLIILVVFVLGVLGFTNSIIAELTVDGTITGVHAFQVGYDEYESALQGALANYESQGQSIDKYFGKESLPSEIQLGY
SVLKVLLDRKVMAFFAMEQDVFPDEAQVQQITDELVSRYISDETTRAQLEMYYGSIENFRKVVEDIVFVRTLSQNVFNAI
VPDYDASATEYFEKNKTDIKNEYESVNAAHILVSTEASAMELKEKILLGELSFEEAAKRYSLDQYSAQQGGNIGELKHGT
VILEFEEAAFAATPGEIVGPVKTDYGYHLIKVNSKTTFDSYEDLKNSKAYEDIMSRFENEAFLGWITKYRQDKKIHYIIY
EEDLKTFGELANLTDPGKFYNRIVNSLFDENNELKAGVPGIIAAFYIQMADDELKQYESREEAFKTIIGICERLPEEEKG
VEHFSELKDKAAENENVKQLLDYAEILGVDSIENVHLRLEEIRNYMREIMNKAKKVAWYLYDKAPDSEKLLEYLYRFDSD
NPKAVYLYTENFYKNQVQPVLADSDIFSSYINAYKQYLGENATETLLGYLIKGLEGRLVEKIVEDESVSEDLRKSALELL
VDAYENACNLPLDNRLKLQYLGTERDYLLKLSELTPEATDVKQLLDAVDERLKELR

Sequences:

>Translated_616_residues
MKKFLIILVVFVLGVLGFTNSIIAELTVDGTITGVHAFQVGYDEYESALQGALANYESQGQSIDKYFGKESLPSEIQLGY
SVLKVLLDRKVMAFFAMEQDVFPDEAQVQQITDELVSRYISDETTRAQLEMYYGSIENFRKVVEDIVFVRTLSQNVFNAI
VPDYDASATEYFEKNKTDIKNEYESVNAAHILVSTEASAMELKEKILLGELSFEEAAKRYSLDQYSAQQGGNIGELKHGT
VILEFEEAAFAATPGEIVGPVKTDYGYHLIKVNSKTTFDSYEDLKNSKAYEDIMSRFENEAFLGWITKYRQDKKIHYIIY
EEDLKTFGELANLTDPGKFYNRIVNSLFDENNELKAGVPGIIAAFYIQMADDELKQYESREEAFKTIIGICERLPEEEKG
VEHFSELKDKAAENENVKQLLDYAEILGVDSIENVHLRLEEIRNYMREIMNKAKKVAWYLYDKAPDSEKLLEYLYRFDSD
NPKAVYLYTENFYKNQVQPVLADSDIFSSYINAYKQYLGENATETLLGYLIKGLEGRLVEKIVEDESVSEDLRKSALELL
VDAYENACNLPLDNRLKLQYLGTERDYLLKLSELTPEATDVKQLLDAVDERLKELR
>Mature_616_residues
MKKFLIILVVFVLGVLGFTNSIIAELTVDGTITGVHAFQVGYDEYESALQGALANYESQGQSIDKYFGKESLPSEIQLGY
SVLKVLLDRKVMAFFAMEQDVFPDEAQVQQITDELVSRYISDETTRAQLEMYYGSIENFRKVVEDIVFVRTLSQNVFNAI
VPDYDASATEYFEKNKTDIKNEYESVNAAHILVSTEASAMELKEKILLGELSFEEAAKRYSLDQYSAQQGGNIGELKHGT
VILEFEEAAFAATPGEIVGPVKTDYGYHLIKVNSKTTFDSYEDLKNSKAYEDIMSRFENEAFLGWITKYRQDKKIHYIIY
EEDLKTFGELANLTDPGKFYNRIVNSLFDENNELKAGVPGIIAAFYIQMADDELKQYESREEAFKTIIGICERLPEEEKG
VEHFSELKDKAAENENVKQLLDYAEILGVDSIENVHLRLEEIRNYMREIMNKAKKVAWYLYDKAPDSEKLLEYLYRFDSD
NPKAVYLYTENFYKNQVQPVLADSDIFSSYINAYKQYLGENATETLLGYLIKGLEGRLVEKIVEDESVSEDLRKSALELL
VDAYENACNLPLDNRLKLQYLGTERDYLLKLSELTPEATDVKQLLDAVDERLKELR

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF05698 Trigger_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 70542; Mature: 70542

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKFLIILVVFVLGVLGFTNSIIAELTVDGTITGVHAFQVGYDEYESALQGALANYESQG
CHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEHHHHHCCHHHHHHHHHHHHHHHHHCC
QSIDKYFGKESLPSEIQLGYSVLKVLLDRKVMAFFAMEQDVFPDEAQVQQITDELVSRYI
CHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SDETTRAQLEMYYGSIENFRKVVEDIVFVRTLSQNVFNAIVPDYDASATEYFEKNKTDIK
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHH
NEYESVNAAHILVSTEASAMELKEKILLGELSFEEAAKRYSLDQYSAQQGGNIGELKHGT
HHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHCCCCCCCCCCCE
VILEFEEAAFAATPGEIVGPVKTDYGYHLIKVNSKTTFDSYEDLKNSKAYEDIMSRFENE
EEEEECCCHHCCCCCHHCCCCCCCCCEEEEEECCCCCCCHHHHHHCCHHHHHHHHHHCCC
AFLGWITKYRQDKKIHYIIYEEDLKTFGELANLTDPGKFYNRIVNSLFDENNELKAGVPG
HHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHH
IIAAFYIQMADDELKQYESREEAFKTIIGICERLPEEEKGVEHFSELKDKAAENENVKQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHH
LDYAEILGVDSIENVHLRLEEIRNYMREIMNKAKKVAWYLYDKAPDSEKLLEYLYRFDSD
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCCC
NPKAVYLYTENFYKNQVQPVLADSDIFSSYINAYKQYLGENATETLLGYLIKGLEGRLVE
CCCEEEEEECCHHHCCCCCHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KIVEDESVSEDLRKSALELLVDAYENACNLPLDNRLKLQYLGTERDYLLKLSELTPEATD
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCCHHH
VKQLLDAVDERLKELR
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKFLIILVVFVLGVLGFTNSIIAELTVDGTITGVHAFQVGYDEYESALQGALANYESQG
CHHHHHHHHHHHHHHHHHHHHHHHHEEECCEEEEHHHHHCCHHHHHHHHHHHHHHHHHCC
QSIDKYFGKESLPSEIQLGYSVLKVLLDRKVMAFFAMEQDVFPDEAQVQQITDELVSRYI
CHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
SDETTRAQLEMYYGSIENFRKVVEDIVFVRTLSQNVFNAIVPDYDASATEYFEKNKTDIK
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHHH
NEYESVNAAHILVSTEASAMELKEKILLGELSFEEAAKRYSLDQYSAQQGGNIGELKHGT
HHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHCCCCCCCCCCCE
VILEFEEAAFAATPGEIVGPVKTDYGYHLIKVNSKTTFDSYEDLKNSKAYEDIMSRFENE
EEEEECCCHHCCCCCHHCCCCCCCCCEEEEEECCCCCCCHHHHHHCCHHHHHHHHHHCCC
AFLGWITKYRQDKKIHYIIYEEDLKTFGELANLTDPGKFYNRIVNSLFDENNELKAGVPG
HHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHH
IIAAFYIQMADDELKQYESREEAFKTIIGICERLPEEEKGVEHFSELKDKAAENENVKQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHH
LDYAEILGVDSIENVHLRLEEIRNYMREIMNKAKKVAWYLYDKAPDSEKLLEYLYRFDSD
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCCC
NPKAVYLYTENFYKNQVQPVLADSDIFSSYINAYKQYLGENATETLLGYLIKGLEGRLVE
CCCEEEEEECCHHHCCCCCHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
KIVEDESVSEDLRKSALELLVDAYENACNLPLDNRLKLQYLGTERDYLLKLSELTPEATD
HHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHHHCCCCHHH
VKQLLDAVDERLKELR
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA