Click here to switch to the map view.

The map label for this gene is rnr [H]

Identifier: 239618067

GI number: 239618067

Start: 1826198

End: 1828396

Strand: Direct

Name: rnr [H]

Synonym: Kole_1697

Alternate gene names: 239618067

Gene position: 1826198-1828396 (Clockwise)

Preceding gene: 239618053

Following gene: 239618068

Centisome position: 79.33

GC content: 41.97

Gene sequence:

>2199_bases
ATGAAGATCAGTAAAAAGAAAATTTTAGAGTTGTTAACTTCCGGGAAATACGTGCCGTCGACCTTTAAAGCTATCGCTAA
GATTCTTGAGGTTAAAGATAAAGATGATAAAAAGAATCTAAGAAAGCTTTTGAAGGAATTAATAGAGGAAGGAAGGATAA
TCAGGGATTCTCGTGGAAGGTATGTGATTCCTGGCGAAAATATGGTGATTGGAGATATACAGTTTACCAGAAGAAGATTC
GGGGCTTTTGTTTCCAGAGACGATGGGGAAGAGGTATACATTGCCTCAGACGATACGGGGTTCGCCCTCGATGGTGATCG
TGTGCTGGTGGAAATAACAGGAACGTATAGAGATCTTCCGAAGGGTTGTGTTGTAAAGGTTTTGAAAAGAGGTCGAACCA
GGATAGTCGGAACCTTTGTAACCAGAGGATTGTTCGCTTTCGTGATACCTGATGATCCGAGGATAAAATACGATTTCTAT
GTTCCACCGGAAGGGTTCAACGGTGCCAAACCGGATGAGAAGGTGCTTTTGAAGATAACCCGGTACCCTTCGCCCGGGAG
AAATCCGGAAGGTGTTGTCGACAAGGTACTGGGTAACGCCATGGATCCAGCCGTTGATCTACCAACGGTTATTTTCAAGC
ACAATCTCCCTGAACCCGGATATTTTCCGGAAGAGGTTTTAAAAGAGGCGGTTAAGGTAGCGAAGCCTCCTACCAAAAAA
GAGATATCGAAAAGGAAGGACTACAGAAAAGATAGAATTTTTACGATTGATGGTGAGGATGCAAAGGATTATGATGACGC
GATAAGCATAAAAAAATTGAAGAACGGGAATTATCTTCTCGGGGTGCACATCGCAGATGTTTCTCATTATGTTAGGGAAG
GAAGTGCGCTTGATAGAGAAGCTTACGAAAGGGGTACCTCGGTTTATCTTCTTGATACGGTTATTCCCATGTTGCCTTTT
GAGCTCTCGAATGGCATTTGTTCTCTGGTAGAAGGTGAGGACAGGCTTACCCTTTCTCTGGAGATGGAGATCGATCCCGG
AGGGAAAGTGGTAGATTTCAAAGTTCATGAAGGGGTTATACGCTCCGTAAGACGACTTACATACACCGAAGTAAACAGAT
TTCTTAATGGAGATAATGATCCGGATCTCCTGAAACATCTCGAACCCGTAAAAAAAGAATTGCTTGTGGCGAGAGAGCTG
GCGAGGATATTGAGGGATTGGCGTAAGAAACGCGGTTCGGTGATGGACATATCTTCGCGAGAGGTGAAAATACTGTTTGA
TGAAAAAGGGCGCGTCGTGGATATTCTTCCTCAGGAACGTGGAGAATCCGAAATAATGATTGAAGAGTTTATGATTAAAG
CAAATGAAACCATCGCCGAGATCTTCAACACTCAGGATATTCCCTTTGTTTACAGGATTCACGAGAAACCCGATCCGGAG
TCTATTATTCAACTAAAACATTATCTTGAGGCTATTGGAATGAAGCTGAGAATACCCAAGAATATTCATCCAAAAGTACT
TCAAGAAATCCTTGAAAAAACGAAAGATCATCCTCTTCACAGTTCGATTGAGCGAATACTCGTTCGCTCTATGAAACGTG
CGGTTTATTCCGAGAGAAATATAGGACATTTTGGCCTTGCGTCCCAGGCTTATACACACTTTACATCGCCGATAAGGCGT
TACCCTGATCTGATAGTTCACAGGTTGCTAAAAAAAATAATTGAAAAGGGACATTTCAGCCCCGAGGAAATAGACCGTTA
TGAGAAAGAACTGCCAAGAATTGCTCAGCACTGTTCAAAGAGGGAACGGATCGCCAACGAAGCCGAATGGGATCTCCTCG
ACATGAAGAAAGTTGAATACATTAGCTATCATATCGGTGAAATCTTTGATTCTGTGATAACAGGAGTAACGAAGTTCGGT
TTGTTTGTGGAAATACCTGAAAAAATGCTTTCCGGTCTAGTGCATGTTTCAACCCTTGATGATTACTATGAGTACAACGA
AACACAGAATATTCTCGTGGGAAAGCACAAAAAACGGGTTTTCAGGATAGGAGATGGAGTGAAAGTAAGAGCGGTTCACG
CTGATAAAACAACCATGGAGGTTGATTTCGTTATTGTTGAAAAGGAAAACAATAAAAATAACAAAAGGAATAATTCTAAA
AACAAAGCAAAGAAAAGGAAGAAAAAACGGCGTTCTTAG

Upstream 100 bases:

>100_bases
TTCATTACCTCCTGCGCTCTAGAAGTGAGATTCAAAAAGAACATTTCGTGTATAATTATACCATGAACATCTATCTCTCT
CCGAGAGGAGGAACGCTTGT

Downstream 100 bases:

>100_bases
TTCGGAGTAAAAAAACTGATTTTTTGCAGAGTATTACGTCCTAATTCGGTTAAATCAATTGTTGACCTTGTCTTTTTAAT
CATTGAGATACGTTTTCTGT

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 732; Mature: 732

Protein sequence:

>732_residues
MKISKKKILELLTSGKYVPSTFKAIAKILEVKDKDDKKNLRKLLKELIEEGRIIRDSRGRYVIPGENMVIGDIQFTRRRF
GAFVSRDDGEEVYIASDDTGFALDGDRVLVEITGTYRDLPKGCVVKVLKRGRTRIVGTFVTRGLFAFVIPDDPRIKYDFY
VPPEGFNGAKPDEKVLLKITRYPSPGRNPEGVVDKVLGNAMDPAVDLPTVIFKHNLPEPGYFPEEVLKEAVKVAKPPTKK
EISKRKDYRKDRIFTIDGEDAKDYDDAISIKKLKNGNYLLGVHIADVSHYVREGSALDREAYERGTSVYLLDTVIPMLPF
ELSNGICSLVEGEDRLTLSLEMEIDPGGKVVDFKVHEGVIRSVRRLTYTEVNRFLNGDNDPDLLKHLEPVKKELLVAREL
ARILRDWRKKRGSVMDISSREVKILFDEKGRVVDILPQERGESEIMIEEFMIKANETIAEIFNTQDIPFVYRIHEKPDPE
SIIQLKHYLEAIGMKLRIPKNIHPKVLQEILEKTKDHPLHSSIERILVRSMKRAVYSERNIGHFGLASQAYTHFTSPIRR
YPDLIVHRLLKKIIEKGHFSPEEIDRYEKELPRIAQHCSKRERIANEAEWDLLDMKKVEYISYHIGEIFDSVITGVTKFG
LFVEIPEKMLSGLVHVSTLDDYYEYNETQNILVGKHKKRVFRIGDGVKVRAVHADKTTMEVDFVIVEKENNKNNKRNNSK
NKAKKRKKKRRS

Sequences:

>Translated_732_residues
MKISKKKILELLTSGKYVPSTFKAIAKILEVKDKDDKKNLRKLLKELIEEGRIIRDSRGRYVIPGENMVIGDIQFTRRRF
GAFVSRDDGEEVYIASDDTGFALDGDRVLVEITGTYRDLPKGCVVKVLKRGRTRIVGTFVTRGLFAFVIPDDPRIKYDFY
VPPEGFNGAKPDEKVLLKITRYPSPGRNPEGVVDKVLGNAMDPAVDLPTVIFKHNLPEPGYFPEEVLKEAVKVAKPPTKK
EISKRKDYRKDRIFTIDGEDAKDYDDAISIKKLKNGNYLLGVHIADVSHYVREGSALDREAYERGTSVYLLDTVIPMLPF
ELSNGICSLVEGEDRLTLSLEMEIDPGGKVVDFKVHEGVIRSVRRLTYTEVNRFLNGDNDPDLLKHLEPVKKELLVAREL
ARILRDWRKKRGSVMDISSREVKILFDEKGRVVDILPQERGESEIMIEEFMIKANETIAEIFNTQDIPFVYRIHEKPDPE
SIIQLKHYLEAIGMKLRIPKNIHPKVLQEILEKTKDHPLHSSIERILVRSMKRAVYSERNIGHFGLASQAYTHFTSPIRR
YPDLIVHRLLKKIIEKGHFSPEEIDRYEKELPRIAQHCSKRERIANEAEWDLLDMKKVEYISYHIGEIFDSVITGVTKFG
LFVEIPEKMLSGLVHVSTLDDYYEYNETQNILVGKHKKRVFRIGDGVKVRAVHADKTTMEVDFVIVEKENNKNNKRNNSK
NKAKKRKKKRRS
>Mature_732_residues
MKISKKKILELLTSGKYVPSTFKAIAKILEVKDKDDKKNLRKLLKELIEEGRIIRDSRGRYVIPGENMVIGDIQFTRRRF
GAFVSRDDGEEVYIASDDTGFALDGDRVLVEITGTYRDLPKGCVVKVLKRGRTRIVGTFVTRGLFAFVIPDDPRIKYDFY
VPPEGFNGAKPDEKVLLKITRYPSPGRNPEGVVDKVLGNAMDPAVDLPTVIFKHNLPEPGYFPEEVLKEAVKVAKPPTKK
EISKRKDYRKDRIFTIDGEDAKDYDDAISIKKLKNGNYLLGVHIADVSHYVREGSALDREAYERGTSVYLLDTVIPMLPF
ELSNGICSLVEGEDRLTLSLEMEIDPGGKVVDFKVHEGVIRSVRRLTYTEVNRFLNGDNDPDLLKHLEPVKKELLVAREL
ARILRDWRKKRGSVMDISSREVKILFDEKGRVVDILPQERGESEIMIEEFMIKANETIAEIFNTQDIPFVYRIHEKPDPE
SIIQLKHYLEAIGMKLRIPKNIHPKVLQEILEKTKDHPLHSSIERILVRSMKRAVYSERNIGHFGLASQAYTHFTSPIRR
YPDLIVHRLLKKIIEKGHFSPEEIDRYEKELPRIAQHCSKRERIANEAEWDLLDMKKVEYISYHIGEIFDSVITGVTKFG
LFVEIPEKMLSGLVHVSTLDDYYEYNETQNILVGKHKKRVFRIGDGVKVRAVHADKTTMEVDFVIVEKENNKNNKRNNSK
NKAKKRKKKRRS

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI190014623, Length=566, Percent_Identity=31.4487632508834, Blast_Score=207, Evalue=3e-53,
Organism=Homo sapiens, GI190014625, Length=566, Percent_Identity=31.4487632508834, Blast_Score=207, Evalue=3e-53,
Organism=Homo sapiens, GI19115966, Length=587, Percent_Identity=29.6422487223169, Blast_Score=194, Evalue=4e-49,
Organism=Homo sapiens, GI219521928, Length=587, Percent_Identity=29.6422487223169, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI134288890, Length=499, Percent_Identity=31.2625250501002, Blast_Score=187, Evalue=4e-47,
Organism=Homo sapiens, GI156105695, Length=395, Percent_Identity=25.5696202531646, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI156105693, Length=393, Percent_Identity=25.6997455470738, Blast_Score=89, Evalue=1e-17,
Organism=Escherichia coli, GI87082383, Length=720, Percent_Identity=34.8611111111111, Blast_Score=421, Evalue=1e-119,
Organism=Escherichia coli, GI1787542, Length=585, Percent_Identity=25.982905982906, Blast_Score=137, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI212645896, Length=500, Percent_Identity=29, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17553506, Length=476, Percent_Identity=29.8319327731092, Blast_Score=168, Evalue=1e-41,
Organism=Saccharomyces cerevisiae, GI6324552, Length=523, Percent_Identity=29.2543021032505, Blast_Score=177, Evalue=6e-45,
Organism=Saccharomyces cerevisiae, GI6323943, Length=428, Percent_Identity=26.6355140186916, Blast_Score=116, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6320499, Length=591, Percent_Identity=25.2115059221658, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI24649634, Length=510, Percent_Identity=31.9607843137255, Blast_Score=219, Evalue=7e-57,
Organism=Drosophila melanogaster, GI19922976, Length=633, Percent_Identity=28.9099526066351, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24654597, Length=633, Percent_Identity=28.9099526066351, Blast_Score=191, Evalue=2e-48,
Organism=Drosophila melanogaster, GI24654592, Length=633, Percent_Identity=28.9099526066351, Blast_Score=191, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 84304; Mature: 84304

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISKKKILELLTSGKYVPSTFKAIAKILEVKDKDDKKNLRKLLKELIEEGRIIRDSRGR
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCC
YVIPGENMVIGDIQFTRRRFGAFVSRDDGEEVYIASDDTGFALDGDRVLVEITGTYRDLP
EEECCCCEEEECHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCEEEEEEECCHHCCC
KGCVVKVLKRGRTRIVGTFVTRGLFAFVIPDDPRIKYDFYVPPEGFNGAKPDEKVLLKIT
HHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCEEEEEEE
RYPSPGRNPEGVVDKVLGNAMDPAVDLPTVIFKHNLPEPGYFPEEVLKEAVKVAKPPTKK
CCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHH
EISKRKDYRKDRIFTIDGEDAKDYDDAISIKKLKNGNYLLGVHIADVSHYVREGSALDRE
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHEEECCCCEEEEEEEHHHHHHHHCCCCCCHH
AYERGTSVYLLDTVIPMLPFELSNGICSLVEGEDRLTLSLEMEIDPGGKVVDFKVHEGVI
HHHCCCEEEEHHHHHHHCCHHHCCCCEEEECCCCEEEEEEEEEECCCCCEEEEEHHHHHH
RSVRRLTYTEVNRFLNGDNDPDLLKHLEPVKKELLVARELARILRDWRKKRGSVMDISSR
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
EVKILFDEKGRVVDILPQERGESEIMIEEFMIKANETIAEIFNTQDIPFVYRIHEKPDPE
EEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCEEEEECCCCCHH
SIIQLKHYLEAIGMKLRIPKNIHPKVLQEILEKTKDHPLHSSIERILVRSMKRAVYSERN
HHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
IGHFGLASQAYTHFTSPIRRYPDLIVHRLLKKIIEKGHFSPEEIDRYEKELPRIAQHCSK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RERIANEAEWDLLDMKKVEYISYHIGEIFDSVITGVTKFGLFVEIPEKMLSGLVHVSTLD
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHCCCEEHHHHH
DYYEYNETQNILVGKHKKRVFRIGDGVKVRAVHADKTTMEVDFVIVEKENNKNNKRNNSK
HHHHHCCCCCEEEECCCCCEEEECCCEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCH
NKAKKRKKKRRS
HHHHHHHHHCCC
>Mature Secondary Structure
MKISKKKILELLTSGKYVPSTFKAIAKILEVKDKDDKKNLRKLLKELIEEGRIIRDSRGR
CCCCHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCEEEECCCC
YVIPGENMVIGDIQFTRRRFGAFVSRDDGEEVYIASDDTGFALDGDRVLVEITGTYRDLP
EEECCCCEEEECHHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCEEEEEEECCHHCCC
KGCVVKVLKRGRTRIVGTFVTRGLFAFVIPDDPRIKYDFYVPPEGFNGAKPDEKVLLKIT
HHHHHHHHHCCCHHHHHHHHHCCEEEEEECCCCCEEEEEEECCCCCCCCCCCCEEEEEEE
RYPSPGRNPEGVVDKVLGNAMDPAVDLPTVIFKHNLPEPGYFPEEVLKEAVKVAKPPTKK
CCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCHH
EISKRKDYRKDRIFTIDGEDAKDYDDAISIKKLKNGNYLLGVHIADVSHYVREGSALDRE
HHHHHHHHCCCCEEEECCCCCCCHHHHHHHEEECCCCEEEEEEEHHHHHHHHCCCCCCHH
AYERGTSVYLLDTVIPMLPFELSNGICSLVEGEDRLTLSLEMEIDPGGKVVDFKVHEGVI
HHHCCCEEEEHHHHHHHCCHHHCCCCEEEECCCCEEEEEEEEEECCCCCEEEEEHHHHHH
RSVRRLTYTEVNRFLNGDNDPDLLKHLEPVKKELLVARELARILRDWRKKRGSVMDISSR
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCC
EVKILFDEKGRVVDILPQERGESEIMIEEFMIKANETIAEIFNTQDIPFVYRIHEKPDPE
EEEEEECCCCCEEEECCCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCEEEEECCCCCHH
SIIQLKHYLEAIGMKLRIPKNIHPKVLQEILEKTKDHPLHSSIERILVRSMKRAVYSERN
HHHHHHHHHHHCCCEEECCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
IGHFGLASQAYTHFTSPIRRYPDLIVHRLLKKIIEKGHFSPEEIDRYEKELPRIAQHCSK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
RERIANEAEWDLLDMKKVEYISYHIGEIFDSVITGVTKFGLFVEIPEKMLSGLVHVSTLD
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHHHCCCEEHHHHH
DYYEYNETQNILVGKHKKRVFRIGDGVKVRAVHADKTTMEVDFVIVEKENNKNNKRNNSK
HHHHHCCCCCEEEECCCCCEEEECCCEEEEEEECCCCEEEEEEEEEECCCCCCCCCCCCH
NKAKKRKKKRRS
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]