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The map label for this gene is pgsA [H]

Identifier: 239617934

GI number: 239617934

Start: 1674380

End: 1674919

Strand: Direct

Name: pgsA [H]

Synonym: Kole_1562

Alternate gene names: 239617934

Gene position: 1674380-1674919 (Clockwise)

Preceding gene: 239617933

Following gene: 239617935

Centisome position: 72.73

GC content: 39.44

Gene sequence:

>540_bases
ATGAATCTGCCTAATATATTGACGTTTTCAAGAATGTTATTGACATTTCCTGTGGTAGCATTACTTACAGTAGAAAATAG
GGTTTCGGTTATTATTTCCGTTCTTTTATTTACGATAGCTGCGTCAACGGATTTCTTTGATGGATATCTGGCGCGGAAGC
TGAATCAGGTTACAGATCTCGGAAAGTTCATGGACCAGATATCGGATAAGATCCTGATAACTTCGCTGTTTCTCGTGTTT
TTGAGTCTGGGAATGATCAATTTGTGGCTTGTTGTTGTCATAGTTGTGAGAGATATATTTGTTTCCGGGTTGAGGATGGC
TGCTGCGTCCAAAGGAGTTGTAATTCCTGCTAATTATTTTGGAAAAGCGAAAACGATATCCCAGATTGTCCTAATTGGTT
GCCTTTATCTGATTTTATTGACTGGAGTTGATTTTCAGTTATTGTTAGATGCTTTGCAATGGATCGTTGGAGTGCTCACC
GTTGCCAGTGGTGGTAGTTATTTCAGGATTTCTGGTAAGATCTTTGAAGGGGGGAAGTAA

Upstream 100 bases:

>100_bases
GACGGCAGCATCTTTCTCAAAAGAGCCGATGAAGCGGGAGAGTTTGTGATGTGTCGTATAACCGGGGTTTACGAGCATGA
CCTGGAAGGTGTGATTGTGG

Downstream 100 bases:

>100_bases
ATTGAGGACCTTTATAGCCATAGATACTGGTAAAGGTGTTGCTTCGGTTGTTGATATGGTTGTCGATAAACTGAAAAGGA
TGGGTTTTAAAGCTTCATGG

Product: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MNLPNILTFSRMLLTFPVVALLTVENRVSVIISVLLFTIAASTDFFDGYLARKLNQVTDLGKFMDQISDKILITSLFLVF
LSLGMINLWLVVVIVVRDIFVSGLRMAAASKGVVIPANYFGKAKTISQIVLIGCLYLILLTGVDFQLLLDALQWIVGVLT
VASGGSYFRISGKIFEGGK

Sequences:

>Translated_179_residues
MNLPNILTFSRMLLTFPVVALLTVENRVSVIISVLLFTIAASTDFFDGYLARKLNQVTDLGKFMDQISDKILITSLFLVF
LSLGMINLWLVVVIVVRDIFVSGLRMAAASKGVVIPANYFGKAKTISQIVLIGCLYLILLTGVDFQLLLDALQWIVGVLT
VASGGSYFRISGKIFEGGK
>Mature_179_residues
MNLPNILTFSRMLLTFPVVALLTVENRVSVIISVLLFTIAASTDFFDGYLARKLNQVTDLGKFMDQISDKILITSLFLVF
LSLGMINLWLVVVIVVRDIFVSGLRMAAASKGVVIPANYFGKAKTISQIVLIGCLYLILLTGVDFQLLLDALQWIVGVLT
VASGGSYFRISGKIFEGGK

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=139, Percent_Identity=33.0935251798561, Blast_Score=80, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI71984834, Length=103, Percent_Identity=33.9805825242718, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71984838, Length=102, Percent_Identity=34.3137254901961, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24650130, Length=104, Percent_Identity=34.6153846153846, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24650126, Length=104, Percent_Identity=34.6153846153846, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24650128, Length=104, Percent_Identity=34.6153846153846, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 19598; Mature: 19598

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPNILTFSRMLLTFPVVALLTVENRVSVIISVLLFTIAASTDFFDGYLARKLNQVTDL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
GKFMDQISDKILITSLFLVFLSLGMINLWLVVVIVVRDIFVSGLRMAAASKGVVIPANYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHC
GKAKTISQIVLIGCLYLILLTGVDFQLLLDALQWIVGVLTVASGGSYFRISGKIFEGGK
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECEECCCCC
>Mature Secondary Structure
MNLPNILTFSRMLLTFPVVALLTVENRVSVIISVLLFTIAASTDFFDGYLARKLNQVTDL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
GKFMDQISDKILITSLFLVFLSLGMINLWLVVVIVVRDIFVSGLRMAAASKGVVIPANYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHC
GKAKTISQIVLIGCLYLILLTGVDFQLLLDALQWIVGVLTVASGGSYFRISGKIFEGGK
CCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7750561; 9384377 [H]