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The map label for this gene is csd [H]

Identifier: 239617862

GI number: 239617862

Start: 1589592

End: 1590815

Strand: Direct

Name: csd [H]

Synonym: Kole_1489

Alternate gene names: 239617862

Gene position: 1589592-1590815 (Clockwise)

Preceding gene: 239617861

Following gene: 239617863

Centisome position: 69.05

GC content: 42.48

Gene sequence:

>1224_bases
ATGTTATCCAGGAACGAATTGAATGATCTTGCGAAAAGCATAAAAAGAGATTTTCCTATATTTGAAATCCATCCGGGGCT
TGTATATCTAGATAACGCTGCGACAACTCAAAAACCAGCCTCTGTAATAGAAAGACAAAGCAGGTTTTATGATCATTCTA
ACGCTAACGTGCACAGAGCTGTTCATTCCCTGGCCGAGGAGGCAACAGACCTGTATGAGCAAGCCAGACAAAGGATAGCC
AGCTTCATAAATTCCAGGTCCGAAGAGGTTATCTTCACTCGAGGAACCACGGAATCTATTAATCTTCTTGCTTATTCTTT
TGCTAAATCCGGGATGGTGAAGAGCTTTGTGGTTCCAACATTTGAACATCACAGTAATTATGTTCCATGGCAGCAGATCT
CCAAGATATTTGGTATCAAGTTTTTACCCTTAAGATTGGATGGATTGGAAGTTCCGTTAGAAAAGATCAAAGAATCGCTA
GAAACGTTGAAGGACCCTTTTGTCTTTTCTATGACGGGGTTAACGAATGCATTGGGCAAAAGGACCCCTTTCGAGGAAAT
CGTAAAACTCGTACATGAGCATGGCGGTTATTTTATTCTTGATGGTGCTCAGTTGATTCCACATGAGCCTTTTGATTTTG
CCGGAACCGGGGTTGACTTTTTGGCTTTCTCCGGGCACAAGATGCTTGGGCCGATGGGGATTGGAGTCCTTGTGGGGAAA
GAAGAGATACTCAAGCGATTGCCTCCATTTCTTTATGGTGGAGAAATGATCGATAGGGTAGGTATGGAAGATACCAGTTT
CGCTCCTTTGCCGTACAAATTTGAGGCTGGTACGCAGAACGTTGCTGGCGCTATAGTTTTAGCAACAGCAATTGACTATC
TTGAAAAATTTGATAGAGAAGAATTAAAGAACCACATTCAGAACCTTACCGATTATGCCAGAGAAAAAATCTCCTCTATA
GACGGCCTCAGGATTTACAGTCCTTCTGATTCACATGGGATCATTAGTTTCGCTCATGATAATATCCATTCTCATGATCT
CGCCGAACTTTTGAGCAGACTTTCCGGGGTTGCCGTAAGAAGTGGGCATCATTGTGCCCAACTTCAATTAAAGGAACTTG
GGGTTGTCTCCCTTTGTAGAGCTTCTTTCTACATTTACAATGTTTTTGAAGATGTTGATAGGCTTGCGGAAGGGATAAGG
AAAGCTTTGAGGTGGTTTGCATGA

Upstream 100 bases:

>100_bases
GAAGAGGAGGCCCTTAAACTCATAGTTATGGGAAGTTTTAATCCTGTCTTAGAAAAGATAGCAGATGAATTTGGTAAAGA
TTATGCAAGGAGGGTTTACG

Downstream 100 bases:

>100_bases
GTGTAGAGGATCTTTATTCTGAATTTATTTTATATCATTACAAGAACTCACCTTACAAAGGTGTACTGGAAGACGCAACC
AATGATGAAGAAGGGAAGAA

Product: cysteine desulfurase, SufS subfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MLSRNELNDLAKSIKRDFPIFEIHPGLVYLDNAATTQKPASVIERQSRFYDHSNANVHRAVHSLAEEATDLYEQARQRIA
SFINSRSEEVIFTRGTTESINLLAYSFAKSGMVKSFVVPTFEHHSNYVPWQQISKIFGIKFLPLRLDGLEVPLEKIKESL
ETLKDPFVFSMTGLTNALGKRTPFEEIVKLVHEHGGYFILDGAQLIPHEPFDFAGTGVDFLAFSGHKMLGPMGIGVLVGK
EEILKRLPPFLYGGEMIDRVGMEDTSFAPLPYKFEAGTQNVAGAIVLATAIDYLEKFDREELKNHIQNLTDYAREKISSI
DGLRIYSPSDSHGIISFAHDNIHSHDLAELLSRLSGVAVRSGHHCAQLQLKELGVVSLCRASFYIYNVFEDVDRLAEGIR
KALRWFA

Sequences:

>Translated_407_residues
MLSRNELNDLAKSIKRDFPIFEIHPGLVYLDNAATTQKPASVIERQSRFYDHSNANVHRAVHSLAEEATDLYEQARQRIA
SFINSRSEEVIFTRGTTESINLLAYSFAKSGMVKSFVVPTFEHHSNYVPWQQISKIFGIKFLPLRLDGLEVPLEKIKESL
ETLKDPFVFSMTGLTNALGKRTPFEEIVKLVHEHGGYFILDGAQLIPHEPFDFAGTGVDFLAFSGHKMLGPMGIGVLVGK
EEILKRLPPFLYGGEMIDRVGMEDTSFAPLPYKFEAGTQNVAGAIVLATAIDYLEKFDREELKNHIQNLTDYAREKISSI
DGLRIYSPSDSHGIISFAHDNIHSHDLAELLSRLSGVAVRSGHHCAQLQLKELGVVSLCRASFYIYNVFEDVDRLAEGIR
KALRWFA
>Mature_407_residues
MLSRNELNDLAKSIKRDFPIFEIHPGLVYLDNAATTQKPASVIERQSRFYDHSNANVHRAVHSLAEEATDLYEQARQRIA
SFINSRSEEVIFTRGTTESINLLAYSFAKSGMVKSFVVPTFEHHSNYVPWQQISKIFGIKFLPLRLDGLEVPLEKIKESL
ETLKDPFVFSMTGLTNALGKRTPFEEIVKLVHEHGGYFILDGAQLIPHEPFDFAGTGVDFLAFSGHKMLGPMGIGVLVGK
EEILKRLPPFLYGGEMIDRVGMEDTSFAPLPYKFEAGTQNVAGAIVLATAIDYLEKFDREELKNHIQNLTDYAREKISSI
DGLRIYSPSDSHGIISFAHDNIHSHDLAELLSRLSGVAVRSGHHCAQLQLKELGVVSLCRASFYIYNVFEDVDRLAEGIR
KALRWFA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=355, Percent_Identity=25.0704225352113, Blast_Score=96, Evalue=9e-20,
Organism=Escherichia coli, GI1787970, Length=403, Percent_Identity=39.454094292804, Blast_Score=303, Evalue=2e-83,
Organism=Escherichia coli, GI1789175, Length=379, Percent_Identity=36.6754617414248, Blast_Score=255, Evalue=4e-69,
Organism=Escherichia coli, GI48994898, Length=395, Percent_Identity=24.8101265822785, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI193211090, Length=337, Percent_Identity=27.299703264095, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI25143064, Length=236, Percent_Identity=27.9661016949153, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319831, Length=352, Percent_Identity=27.5568181818182, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI20129463, Length=230, Percent_Identity=29.5652173913043, Blast_Score=109, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45744; Mature: 45744

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRNELNDLAKSIKRDFPIFEIHPGLVYLDNAATTQKPASVIERQSRFYDHSNANVHRA
CCCHHHHHHHHHHHHHCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHH
VHSLAEEATDLYEQARQRIASFINSRSEEVIFTRGTTESINLLAYSFAKSGMVKSFVVPT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHCCC
FEHHSNYVPWQQISKIFGIKFLPLRLDGLEVPLEKIKESLETLKDPFVFSMTGLTNALGK
HHHCCCCCCHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHCC
RTPFEEIVKLVHEHGGYFILDGAQLIPHEPFDFAGTGVDFLAFSGHKMLGPMGIGVLVGK
CCCHHHHHHHHHHCCCEEEEECCHHCCCCCCCCCCCCHHHEEECCCCCCCCCCCEEEECH
EEILKRLPPFLYGGEMIDRVGMEDTSFAPLPYKFEAGTQNVAGAIVLATAIDYLEKFDRE
HHHHHHCCCHHCCCHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCHH
ELKNHIQNLTDYAREKISSIDGLRIYSPSDSHGIISFAHDNIHSHDLAELLSRLSGVAVR
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHC
SGHHCAQLQLKELGVVSLCRASFYIYNVFEDVDRLAEGIRKALRWFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLSRNELNDLAKSIKRDFPIFEIHPGLVYLDNAATTQKPASVIERQSRFYDHSNANVHRA
CCCHHHHHHHHHHHHHCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCHHHHH
VHSLAEEATDLYEQARQRIASFINSRSEEVIFTRGTTESINLLAYSFAKSGMVKSFVVPT
HHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCHHHHHCCC
FEHHSNYVPWQQISKIFGIKFLPLRLDGLEVPLEKIKESLETLKDPFVFSMTGLTNALGK
HHHCCCCCCHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHCC
RTPFEEIVKLVHEHGGYFILDGAQLIPHEPFDFAGTGVDFLAFSGHKMLGPMGIGVLVGK
CCCHHHHHHHHHHCCCEEEEECCHHCCCCCCCCCCCCHHHEEECCCCCCCCCCCEEEECH
EEILKRLPPFLYGGEMIDRVGMEDTSFAPLPYKFEAGTQNVAGAIVLATAIDYLEKFDRE
HHHHHHCCCHHCCCHHHHHCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHCHH
ELKNHIQNLTDYAREKISSIDGLRIYSPSDSHGIISFAHDNIHSHDLAELLSRLSGVAVR
HHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHCCHHC
SGHHCAQLQLKELGVVSLCRASFYIYNVFEDVDRLAEGIRKALRWFA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]