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The map label for this gene is fps [H]

Identifier: 239617815

GI number: 239617815

Start: 1541734

End: 1542591

Strand: Reverse

Name: fps [H]

Synonym: Kole_1441

Alternate gene names: 239617815

Gene position: 1542591-1541734 (Counterclockwise)

Preceding gene: 239617816

Following gene: 239617810

Centisome position: 67.01

GC content: 41.03

Gene sequence:

>858_bases
ATGAAGACGAAGACGCTGAAGATAAATGATTTTAGAAAAGAATTCGATAAGTTTCTTCGAGATCATCTCGAAAGACTGAT
GGTATGTTCATCTTTTTCCAGTATAATCAACTACACCCCATTAACAGGGGGCAAAAGGTTAAGACCCTATTTAATAGCTC
TCTTCTCGCAAGCTATCGGTTTGCCTTCAGAACTTTATATGAAGCTCGGAGTAGCTGTCGAACTCTTTCATAGTGGCAGT
CTCATACACGATGACCTTCCAGCGATAGACAACGACGATTTCAGAAGGGGAAAGCCCTCACTTCATAAGGCTTTCGATGA
AGCCAGTGCCATTCTTGCCGGGGACTTTCTAATGCTGTACCCTGTAAAAGTGCTTCAGGAACTGACAATAAACGAACACT
TAAAATTCCTTCTGATAAATGAATGGATTCGTACAGCGTTATCAATTATTGAAGGTGAATATCTCGACGTAACGTACGAA
CCATCTTCAAACACGAAAGATGTTAACAGGATTCATAGATTGAAAACAGCCGAGCTTTTTGGCTTTTGTTTCTCATCACC
ATTCATCTGCGCCGACCGAATGGAAGAAGCAAAGAAGATGAAAGAAACAGGATTACGCTTCGGGCACATCTTTCAGGTCC
TTGACGATATCAAAGACAAGCTTCAACCTATAGAAATTCTTGGAAAAACACCGGGCAAAGATGAAAAGCTTAATCGTCCG
TCAATTCTGCGATTCATGTCTCCCGAAGAAGCTCTGAACACCTCTGAAAAAGACTTCAAAACACTTCTGGAAAATATAGA
ATATCCAGAGGTTTGCGAAGGTCTTAAAAAGCTGTGGAAACTCATCGTGAAGGCTTGA

Upstream 100 bases:

>100_bases
AAAACTGATAAAGACGAAGATCAGGAGTTTAAAGAATTCGTAAAACGGTTCGATATTGAAGATTTAAGAGAATATTTTGA
AAGAAGGCAGCAGGAAAACG

Downstream 100 bases:

>100_bases
TTCAAAAAAAGAAGGAGTCCAATGCTTTTAAGAAACTGTCCACGCTGTAAAATCTTTTTTCGGGGCTTAATGCCATCGCC
TTAAGGATAAGCTTCTTTAT

Product: Polyprenyl synthetase

Products: NA

Alternate protein names: FPP synthase; (2E,6E)-farnesyl diphosphate synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MKTKTLKINDFRKEFDKFLRDHLERLMVCSSFSSIINYTPLTGGKRLRPYLIALFSQAIGLPSELYMKLGVAVELFHSGS
LIHDDLPAIDNDDFRRGKPSLHKAFDEASAILAGDFLMLYPVKVLQELTINEHLKFLLINEWIRTALSIIEGEYLDVTYE
PSSNTKDVNRIHRLKTAELFGFCFSSPFICADRMEEAKKMKETGLRFGHIFQVLDDIKDKLQPIEILGKTPGKDEKLNRP
SILRFMSPEEALNTSEKDFKTLLENIEYPEVCEGLKKLWKLIVKA

Sequences:

>Translated_285_residues
MKTKTLKINDFRKEFDKFLRDHLERLMVCSSFSSIINYTPLTGGKRLRPYLIALFSQAIGLPSELYMKLGVAVELFHSGS
LIHDDLPAIDNDDFRRGKPSLHKAFDEASAILAGDFLMLYPVKVLQELTINEHLKFLLINEWIRTALSIIEGEYLDVTYE
PSSNTKDVNRIHRLKTAELFGFCFSSPFICADRMEEAKKMKETGLRFGHIFQVLDDIKDKLQPIEILGKTPGKDEKLNRP
SILRFMSPEEALNTSEKDFKTLLENIEYPEVCEGLKKLWKLIVKA
>Mature_285_residues
MKTKTLKINDFRKEFDKFLRDHLERLMVCSSFSSIINYTPLTGGKRLRPYLIALFSQAIGLPSELYMKLGVAVELFHSGS
LIHDDLPAIDNDDFRRGKPSLHKAFDEASAILAGDFLMLYPVKVLQELTINEHLKFLLINEWIRTALSIIEGEYLDVTYE
PSSNTKDVNRIHRLKTAELFGFCFSSPFICADRMEEAKKMKETGLRFGHIFQVLDDIKDKLQPIEILGKTPGKDEKLNRP
SILRFMSPEEALNTSEKDFKTLLENIEYPEVCEGLKKLWKLIVKA

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789578, Length=223, Percent_Identity=31.390134529148, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786623, Length=227, Percent_Identity=33.920704845815, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17505681, Length=253, Percent_Identity=26.0869565217391, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24651612, Length=216, Percent_Identity=26.8518518518519, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.10 [H]

Molecular weight: Translated: 32777; Mature: 32777

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTKTLKINDFRKEFDKFLRDHLERLMVCSSFSSIINYTPLTGGKRLRPYLIALFSQAIG
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
LPSELYMKLGVAVELFHSGSLIHDDLPAIDNDDFRRGKPSLHKAFDEASAILAGDFLMLY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
PVKVLQELTINEHLKFLLINEWIRTALSIIEGEYLDVTYEPSSNTKDVNRIHRLKTAELF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
GFCFSSPFICADRMEEAKKMKETGLRFGHIFQVLDDIKDKLQPIEILGKTPGKDEKLNRP
HHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SILRFMSPEEALNTSEKDFKTLLENIEYPEVCEGLKKLWKLIVKA
HHHHHCCCHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTKTLKINDFRKEFDKFLRDHLERLMVCSSFSSIINYTPLTGGKRLRPYLIALFSQAIG
CCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHC
LPSELYMKLGVAVELFHSGSLIHDDLPAIDNDDFRRGKPSLHKAFDEASAILAGDFLMLY
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
PVKVLQELTINEHLKFLLINEWIRTALSIIEGEYLDVTYEPSSNTKDVNRIHRLKTAELF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
GFCFSSPFICADRMEEAKKMKETGLRFGHIFQVLDDIKDKLQPIEILGKTPGKDEKLNRP
HHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
SILRFMSPEEALNTSEKDFKTLLENIEYPEVCEGLKKLWKLIVKA
HHHHHCCCHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9515931 [H]