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The map label for this gene is wecB [C]

Identifier: 239617737

GI number: 239617737

Start: 1446177

End: 1447289

Strand: Direct

Name: wecB [C]

Synonym: Kole_1361

Alternate gene names: 239617737

Gene position: 1446177-1447289 (Clockwise)

Preceding gene: 239617736

Following gene: 239617738

Centisome position: 62.82

GC content: 43.85

Gene sequence:

>1113_bases
TTGAAAAAAATAGCGCTGGTTTTTGGTACGCGGCCTGAGGCGATAAAAATGGCACCGGTTTATCTTGCTTTGAATGGTTC
TCCATTGCAACCTGTAGTTATCGCCACGGCCCAGCACAGAGAAATGCTCGATCAGGTGCTCGAATTGTTTGGTATAACAC
CGGATTACGATCTGAATATCATGAAAGAAAGGCAGAGCCTTTCAGATTTGACATCGAGACTTACTAAAGCTCTGGAAGAT
ATATATAAGAATGAGAAATTTGCTGCCACGCTCGTTCAGGGAGACACAACCACTACCTTTGTGGGTGCTCTGGTATCCTT
TTATCACAAAGTCCCTGTGGGGCATGTGGAAGCCGGATTAAGAACCAATGATATTTACAATCCTTTCCCTGAAGAGGTAA
ACAGAAGACTTGTTAGCGTTATAGCCACCTATCATTATCCTCCCACCGAACAAGCGAGGAAGAATCTTCTAGCAGCCGGG
ATTTCGGAGAAAAACATGCTGGTCACTGGTAACACAGTGATAGATGCCCTTTTATGGACTACAAAAAATAAGAGCCTTGA
AGCCAGGAGAATTCGTGAATCTCTTGGTTTGGAAGATGAGAGTTATATACTCATGACCATGCACAGGCGTGAAAATTGGG
GAGAACCTATGAGGGAGGTTATGAAAGCCATCAAAAAGATTCTTTCTGAGAAGAAGGACCTGAAGCTCGTTTTTCCAGTC
CATTTGAACCCGGTTGTTAGAGAAGTAGTTTATGAAGAATTGGGAGAGTATCCCCGGGTTTTACTTACAGAACCACTTGA
TTATTTGCCTTTTGTTTCCTTGATGGAAAAAGCTAAGCTTATTCTTACCGATTCTGGAGGGATACAGGAAGAGGCTCCTG
CTCTTGGAAAACCCACATTGGTTTTGAGAAGCGAAACGGAAAGACCGGAAGCTTTAGAAGCCGGAACAGCAAAACTTGTG
GGTACATCAGCGGAGAAAATAGTCGAAGAAACGCTCAAGCTTCTGAATTCGACTGAAGAATACGAGAAAATGGCGAAATC
TGTGAATCCTTTTGGCGATGGGAAGGCTTCCGAGAGAATAGTTACACACCTTATCGAGGCTTTCGGAGCGTGA

Upstream 100 bases:

>100_bases
AACTCAATTTTCTATGGTCAGGTGATTGGCTGGTTGGCTTCTCCATTAATGATACAATATGACAAAATGATGAAATATTG
AGCTCTAGGGGGGAACTCGG

Downstream 100 bases:

>100_bases
TATAGTGTCAGGTGAAATAATGGTGGAAACAATTGTTTTGATCATTCTTATTGTACAAGCAGTGCTGATGATTCCTATCA
GTATCCTTTTTGTCGTGTTC

Product: UDP-N-acetylglucosamine 2-epimerase

Products: NA

Alternate protein names: UDP-GlcNAc-2-epimerase [H]

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MKKIALVFGTRPEAIKMAPVYLALNGSPLQPVVIATAQHREMLDQVLELFGITPDYDLNIMKERQSLSDLTSRLTKALED
IYKNEKFAATLVQGDTTTTFVGALVSFYHKVPVGHVEAGLRTNDIYNPFPEEVNRRLVSVIATYHYPPTEQARKNLLAAG
ISEKNMLVTGNTVIDALLWTTKNKSLEARRIRESLGLEDESYILMTMHRRENWGEPMREVMKAIKKILSEKKDLKLVFPV
HLNPVVREVVYEELGEYPRVLLTEPLDYLPFVSLMEKAKLILTDSGGIQEEAPALGKPTLVLRSETERPEALEAGTAKLV
GTSAEKIVEETLKLLNSTEEYEKMAKSVNPFGDGKASERIVTHLIEAFGA

Sequences:

>Translated_370_residues
MKKIALVFGTRPEAIKMAPVYLALNGSPLQPVVIATAQHREMLDQVLELFGITPDYDLNIMKERQSLSDLTSRLTKALED
IYKNEKFAATLVQGDTTTTFVGALVSFYHKVPVGHVEAGLRTNDIYNPFPEEVNRRLVSVIATYHYPPTEQARKNLLAAG
ISEKNMLVTGNTVIDALLWTTKNKSLEARRIRESLGLEDESYILMTMHRRENWGEPMREVMKAIKKILSEKKDLKLVFPV
HLNPVVREVVYEELGEYPRVLLTEPLDYLPFVSLMEKAKLILTDSGGIQEEAPALGKPTLVLRSETERPEALEAGTAKLV
GTSAEKIVEETLKLLNSTEEYEKMAKSVNPFGDGKASERIVTHLIEAFGA
>Mature_370_residues
MKKIALVFGTRPEAIKMAPVYLALNGSPLQPVVIATAQHREMLDQVLELFGITPDYDLNIMKERQSLSDLTSRLTKALED
IYKNEKFAATLVQGDTTTTFVGALVSFYHKVPVGHVEAGLRTNDIYNPFPEEVNRRLVSVIATYHYPPTEQARKNLLAAG
ISEKNMLVTGNTVIDALLWTTKNKSLEARRIRESLGLEDESYILMTMHRRENWGEPMREVMKAIKKILSEKKDLKLVFPV
HLNPVVREVVYEELGEYPRVLLTEPLDYLPFVSLMEKAKLILTDSGGIQEEAPALGKPTLVLRSETERPEALEAGTAKLV
GTSAEKIVEETLKLLNSTEEYEKMAKSVNPFGDGKASERIVTHLIEAFGA

Specific function: Catalyzes The Reversible Epimerization At C-2 Of UDP-N- Acetylglucosamine (UDP-Glcnac) And Thereby Provides Bacteria With UDP-N-Acetylmannosamine (UDP-Mannac), The Activated Donor Of Mannac Residues. Also Involved In Bacteriophage N4 Adsorption. [C]

COG id: COG0381

COG function: function code M; UDP-N-acetylglucosamine 2-epimerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-N-acetylglucosamine 2-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI48994967, Length=369, Percent_Identity=51.7615176151762, Blast_Score=372, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003331 [H]

Pfam domain/function: PF02350 Epimerase_2 [H]

EC number: =5.1.3.14 [H]

Molecular weight: Translated: 41450; Mature: 41450

Theoretical pI: Translated: 5.98; Mature: 5.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIALVFGTRPEAIKMAPVYLALNGSPLQPVVIATAQHREMLDQVLELFGITPDYDLNI
CCEEEEEECCCCCCEEEEEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCHH
MKERQSLSDLTSRLTKALEDIYKNEKFAATLVQGDTTTTFVGALVSFYHKVPVGHVEAGL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHCCC
RTNDIYNPFPEEVNRRLVSVIATYHYPPTEQARKNLLAAGISEKNMLVTGNTVIDALLWT
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHH
TKNKSLEARRIRESLGLEDESYILMTMHRRENWGEPMREVMKAIKKILSEKKDLKLVFPV
CCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEC
HLNPVVREVVYEELGEYPRVLLTEPLDYLPFVSLMEKAKLILTDSGGIQEEAPALGKPTL
CCCHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCEE
VLRSETERPEALEAGTAKLVGTSAEKIVEETLKLLNSTEEYEKMAKSVNPFGDGKASERI
EEECCCCCCHHHHCCCHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHH
VTHLIEAFGA
HHHHHHHHCC
>Mature Secondary Structure
MKKIALVFGTRPEAIKMAPVYLALNGSPLQPVVIATAQHREMLDQVLELFGITPDYDLNI
CCEEEEEECCCCCCEEEEEEEEEECCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCHH
MKERQSLSDLTSRLTKALEDIYKNEKFAATLVQGDTTTTFVGALVSFYHKVPVGHVEAGL
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCHHHCCC
RTNDIYNPFPEEVNRRLVSVIATYHYPPTEQARKNLLAAGISEKNMLVTGNTVIDALLWT
CCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHH
TKNKSLEARRIRESLGLEDESYILMTMHRRENWGEPMREVMKAIKKILSEKKDLKLVFPV
CCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEC
HLNPVVREVVYEELGEYPRVLLTEPLDYLPFVSLMEKAKLILTDSGGIQEEAPALGKPTL
CCCHHHHHHHHHHHCCCCCEECCCCCHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCCEE
VLRSETERPEALEAGTAKLVGTSAEKIVEETLKLLNSTEEYEKMAKSVNPFGDGKASERI
EEECCCCCCHHHHCCCHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHH
VTHLIEAFGA
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]