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The map label for this gene is bvgS [H]

Identifier: 239617738

GI number: 239617738

Start: 1447294

End: 1449036

Strand: Direct

Name: bvgS [H]

Synonym: Kole_1362

Alternate gene names: 239617738

Gene position: 1447294-1449036 (Clockwise)

Preceding gene: 239617737

Following gene: 239617739

Centisome position: 62.87

GC content: 37.35

Gene sequence:

>1743_bases
GTGTCAGGTGAAATAATGGTGGAAACAATTGTTTTGATCATTCTTATTGTACAAGCAGTGCTGATGATTCCTATCAGTAT
CCTTTTTGTCGTGTTCAACAGACGCTCTAAAGATATAATACCAGCCTGGGATTTCTTCTGGATTTCTTACGCTGCGAATC
GTATTATCGCCATCTATAAGTATTTGAAAGGCTACAATATAATAATAGCGCTGTCGGAGAGTATTTCGTATAGCCTTCAA
ATTTGGGCTTTACTCGTGGTTATAAAATTTTACTCAGATGATACGAAGAAATATAATACTTTCTTCTATCTACCGATTCC
AGCAATGGTTATTCTGAAATTTCTTGGTGTTTACAATTGGTATTATCAGGCTTTGGGGTTTGTATTGCTGGGAATTGTTA
TGGCCTGGGTTGGATTGGTTCTAATAAAATCGAAAAAAATGCAAACAAAATTTGGTCGAATCTTAAGCTGGGTTGTTTTC
TTTTCAGGGATTCAAACTGCTCTGTACATTTTCTCAAGAAATACAGTATTTGCCCTGATAAGATACCCAATAAACATTCT
ATTGGCGTTCTTGATCTTTATTTACTATCTTCTATACAGAATCGATGATGAAGTAAATAAACGTGTTAGTACCGAGCAGA
TGCTGAACAACATGGCTGAAAATATCTCAGACCACCTTGCATTGAGAATAAACGAACGCGGAGAAATTCTTTACTCTACC
CCCTCTATGAATAACTTTGTGAGTTCAACGAAGGAACTTTCCAGGTTTCTAAGGGGCTTTGATGAGGATGACAGGAAAAA
GTTTCTTACAACCTTTGAAGATTCCTTGTTTTTTGGAAGACAAGGTGAATTAGATCTTTCCATAAAACCGGAAGGGAGCT
CTTTTGAGAAGAGATTCCTGGTTAAGTTTTATCCTACAAAGTATCTCGGAACAAAGGTTGTAGATGTATTTTTTCTGGAT
ATAACAGAACAGTTAAGACGAGAGAATTTTTTGAAGAAGCAAAAGGAAGAAGCTGAATTACTCAATAAATCACAAGCGGC
TTTCTTTTCCAATATATCTCACGAACTTCGAACGCCGCTTACGATTATTCTTGGTTATTCAGAAATGCTCTATGAGATAG
TTGGACCTGCGGAAAGAAGAATGGTTTCTATGATCGCTGATTCGGCGAATTACCTTCTCAAACTGGTAAACGATATACTG
GATATCTCAAAAATCACTTCCCGCGCTGTAAAGGTTGAACCTGAAAGTGTGAACATAAAGCTTCTCGTAAACAATATTCT
CGAACAATTTAATAGTCTGGTGGAGAAAAAGGGTATCAAATTAGAATCTAAATTGATGATTTGCAGGGAAAACTTTGTAA
CAGACAAAACAAAGTTGCAGAGGATTCTCACAAATCTTATAGGTAACGCTATAAAATTCACTAATGAAGGAGTCGTCAGG
GTCCTGGTCAAAGAAGAGGGAAGTAATGTGTTCCTTTTTGCCGTAGAGGATACTGGAATAGGTATAAAGAAAGAATATCA
GGATAAGGTATTCGAACGCTTTGTCCAAATTAAAGATGATAGGTCCCGTGTAAAGTTCAAAAAAGGTACCGGGCTCGGAT
TACCTCTAACCAAGGAGTTAGTGCAGTTGCTCGGCGGGAGGATCTGGCTGCAATCTGAATATGGGAAAGGAACCACAGTA
TATTTTACTCTTAAAGAGTTGAACCACTCCGAAGAGAAGCAAAAAGGTGATAAAAATGGATGA

Upstream 100 bases:

>100_bases
GAATACGAGAAAATGGCGAAATCTGTGAATCCTTTTGGCGATGGGAAGGCTTCCGAGAGAATAGTTACACACCTTATCGA
GGCTTTCGGAGCGTGATATA

Downstream 100 bases:

>100_bases
TGAATTTGAGGCGCTTTTTCAGGAACTGCAGAATGAGAGGGCATGTCCTGAATGTGTTAAGTGTGGATATTGCTGTAAAA
ACACTCCCTGTTATTGTGGA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 580; Mature: 579

Protein sequence:

>580_residues
MSGEIMVETIVLIILIVQAVLMIPISILFVVFNRRSKDIIPAWDFFWISYAANRIIAIYKYLKGYNIIIALSESISYSLQ
IWALLVVIKFYSDDTKKYNTFFYLPIPAMVILKFLGVYNWYYQALGFVLLGIVMAWVGLVLIKSKKMQTKFGRILSWVVF
FSGIQTALYIFSRNTVFALIRYPINILLAFLIFIYYLLYRIDDEVNKRVSTEQMLNNMAENISDHLALRINERGEILYST
PSMNNFVSSTKELSRFLRGFDEDDRKKFLTTFEDSLFFGRQGELDLSIKPEGSSFEKRFLVKFYPTKYLGTKVVDVFFLD
ITEQLRRENFLKKQKEEAELLNKSQAAFFSNISHELRTPLTIILGYSEMLYEIVGPAERRMVSMIADSANYLLKLVNDIL
DISKITSRAVKVEPESVNIKLLVNNILEQFNSLVEKKGIKLESKLMICRENFVTDKTKLQRILTNLIGNAIKFTNEGVVR
VLVKEEGSNVFLFAVEDTGIGIKKEYQDKVFERFVQIKDDRSRVKFKKGTGLGLPLTKELVQLLGGRIWLQSEYGKGTTV
YFTLKELNHSEEKQKGDKNG

Sequences:

>Translated_580_residues
MSGEIMVETIVLIILIVQAVLMIPISILFVVFNRRSKDIIPAWDFFWISYAANRIIAIYKYLKGYNIIIALSESISYSLQ
IWALLVVIKFYSDDTKKYNTFFYLPIPAMVILKFLGVYNWYYQALGFVLLGIVMAWVGLVLIKSKKMQTKFGRILSWVVF
FSGIQTALYIFSRNTVFALIRYPINILLAFLIFIYYLLYRIDDEVNKRVSTEQMLNNMAENISDHLALRINERGEILYST
PSMNNFVSSTKELSRFLRGFDEDDRKKFLTTFEDSLFFGRQGELDLSIKPEGSSFEKRFLVKFYPTKYLGTKVVDVFFLD
ITEQLRRENFLKKQKEEAELLNKSQAAFFSNISHELRTPLTIILGYSEMLYEIVGPAERRMVSMIADSANYLLKLVNDIL
DISKITSRAVKVEPESVNIKLLVNNILEQFNSLVEKKGIKLESKLMICRENFVTDKTKLQRILTNLIGNAIKFTNEGVVR
VLVKEEGSNVFLFAVEDTGIGIKKEYQDKVFERFVQIKDDRSRVKFKKGTGLGLPLTKELVQLLGGRIWLQSEYGKGTTV
YFTLKELNHSEEKQKGDKNG
>Mature_579_residues
SGEIMVETIVLIILIVQAVLMIPISILFVVFNRRSKDIIPAWDFFWISYAANRIIAIYKYLKGYNIIIALSESISYSLQI
WALLVVIKFYSDDTKKYNTFFYLPIPAMVILKFLGVYNWYYQALGFVLLGIVMAWVGLVLIKSKKMQTKFGRILSWVVFF
SGIQTALYIFSRNTVFALIRYPINILLAFLIFIYYLLYRIDDEVNKRVSTEQMLNNMAENISDHLALRINERGEILYSTP
SMNNFVSSTKELSRFLRGFDEDDRKKFLTTFEDSLFFGRQGELDLSIKPEGSSFEKRFLVKFYPTKYLGTKVVDVFFLDI
TEQLRRENFLKKQKEEAELLNKSQAAFFSNISHELRTPLTIILGYSEMLYEIVGPAERRMVSMIADSANYLLKLVNDILD
ISKITSRAVKVEPESVNIKLLVNNILEQFNSLVEKKGIKLESKLMICRENFVTDKTKLQRILTNLIGNAIKFTNEGVVRV
LVKEEGSNVFLFAVEDTGIGIKKEYQDKVFERFVQIKDDRSRVKFKKGTGLGLPLTKELVQLLGGRIWLQSEYGKGTTVY
FTLKELNHSEEKQKGDKNG

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=260, Percent_Identity=36.5384615384615, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI145693157, Length=270, Percent_Identity=31.8518518518519, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1789149, Length=240, Percent_Identity=34.1666666666667, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1788713, Length=252, Percent_Identity=31.7460317460317, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI87081816, Length=241, Percent_Identity=31.9502074688797, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786600, Length=231, Percent_Identity=29.004329004329, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=28.8990825688073, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=25.8771929824561, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788393, Length=214, Percent_Identity=27.1028037383178, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1786912, Length=268, Percent_Identity=25, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87082128, Length=223, Percent_Identity=26.9058295964126, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788549, Length=255, Percent_Identity=26.2745098039216, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790346, Length=216, Percent_Identity=26.8518518518519, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788279, Length=203, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787894, Length=220, Percent_Identity=24.0909090909091, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790861, Length=204, Percent_Identity=28.4313725490196, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 67075; Mature: 66943

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGEIMVETIVLIILIVQAVLMIPISILFVVFNRRSKDIIPAWDFFWISYAANRIIAIYK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YLKGYNIIIALSESISYSLQIWALLVVIKFYSDDTKKYNTFFYLPIPAMVILKFLGVYNW
HHCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEECEEEEECHHHHHHHHHHHHHHH
YYQALGFVLLGIVMAWVGLVLIKSKKMQTKFGRILSWVVFFSGIQTALYIFSRNTVFALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHH
RYPINILLAFLIFIYYLLYRIDDEVNKRVSTEQMLNNMAENISDHLALRINERGEILYST
HHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHCHHHHEEEEECCCCCEEEEC
PSMNNFVSSTKELSRFLRGFDEDDRKKFLTTFEDSLFFGRQGELDLSIKPEGSSFEKRFL
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCCCEEEEECCCCCCHHHEEE
VKFYPTKYLGTKVVDVFFLDITEQLRRENFLKKQKEEAELLNKSQAAFFSNISHELRTPL
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
TIILGYSEMLYEIVGPAERRMVSMIADSANYLLKLVNDILDISKITSRAVKVEPESVNIK
EEEECHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEE
LLVNNILEQFNSLVEKKGIKLESKLMICRENFVTDKTKLQRILTNLIGNAIKFTNEGVVR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEECCCCEEE
VLVKEEGSNVFLFAVEDTGIGIKKEYQDKVFERFVQIKDDRSRVKFKKGTGLGLPLTKEL
EEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCHHHHH
VQLLGGRIWLQSEYGKGTTVYFTLKELNHSEEKQKGDKNG
HHHHCCEEEEEECCCCCEEEEEEHHHCCCCHHHHCCCCCC
>Mature Secondary Structure 
SGEIMVETIVLIILIVQAVLMIPISILFVVFNRRSKDIIPAWDFFWISYAANRIIAIYK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
YLKGYNIIIALSESISYSLQIWALLVVIKFYSDDTKKYNTFFYLPIPAMVILKFLGVYNW
HHCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEECEEEEECHHHHHHHHHHHHHHH
YYQALGFVLLGIVMAWVGLVLIKSKKMQTKFGRILSWVVFFSGIQTALYIFSRNTVFALI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHH
RYPINILLAFLIFIYYLLYRIDDEVNKRVSTEQMLNNMAENISDHLALRINERGEILYST
HHHHHHHHHHHHHHHHHHHHHCHHHHHCCCHHHHHHHHHHCHHHHEEEEECCCCCEEEEC
PSMNNFVSSTKELSRFLRGFDEDDRKKFLTTFEDSLFFGRQGELDLSIKPEGSSFEKRFL
CCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCCCCEEEEECCCCCCHHHEEE
VKFYPTKYLGTKVVDVFFLDITEQLRRENFLKKQKEEAELLNKSQAAFFSNISHELRTPL
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
TIILGYSEMLYEIVGPAERRMVSMIADSANYLLKLVNDILDISKITSRAVKVEPESVNIK
EEEECHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEE
LLVNNILEQFNSLVEKKGIKLESKLMICRENFVTDKTKLQRILTNLIGNAIKFTNEGVVR
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHEECCCCEEE
VLVKEEGSNVFLFAVEDTGIGIKKEYQDKVFERFVQIKDDRSRVKFKKGTGLGLPLTKEL
EEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCHHHHH
VQLLGGRIWLQSEYGKGTTVYFTLKELNHSEEKQKGDKNG
HHHHCCEEEEEECCCCCEEEEEEHHHCCCCHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]