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The map label for this gene is 239617659

Identifier: 239617659

GI number: 239617659

Start: 1361517

End: 1363193

Strand: Reverse

Name: 239617659

Synonym: Kole_1282

Alternate gene names: NA

Gene position: 1363193-1361517 (Counterclockwise)

Preceding gene: 239617660

Following gene: 239617658

Centisome position: 59.21

GC content: 35.84

Gene sequence:

>1677_bases
ATGTGGTTTGACATGTTGATCGCGGTTATCCCAGCTCGAGGTGGATCCAAAGGTATTAGGCGAAAAAATCTTAGATTGCT
TAATGCAAAGCCCCTAATCTCTTATGTTCTTGAGGCTTCTATTGCTTCAAGAAAAATTGATGCTGTTATCGTCACAACAG
ATGATTACGAGATAGCGGAATACTGTAAACAATTCAACGTGATTATTCGCGAGAGGCCAAAACATCTCGGAAAAGACTCG
GTTCCTCTTGATCCGGTAGTAAGCGATTCTGTTCAATGGTTTGAAGAGCATTATAGCGCTAACGTTGAAACTGTGATAAC
GATTCAGCCAACCTCACCTTTGATCACTTCGTCCCTTATCGATGAAGCCATTGATAATTTTTTTGCTCAAGACCTTGACT
CGTTGATAAGCGTTGTTGACAATACCCATCTTGGTTGGAAAATCGAAAACAATGAACTTAAACCAGATTATAAAAAACGG
CTGAATCGTCAGTGGTTACCAAAAAGATTTAAAGAGACAGGAGCTTTTGTTATCAGCAAAAGAGAAATAATTAATTCAGG
AACAAGAATCGGGGGAAAAGTGGGAATCTACGAAGTTCCGCTTGAAGCTTCTATTGATTTAGATTCTCCAAATGATTGGT
TACTGTGCTCAGCTTTGCTCAAGAGATTGAGTGTCAAATTTGTTGTTACTGGAAATAGTAACACTGGAATGGGACATATT
TACAGAACACTAACTCTGGCAGATTTTTGGCTTGGGCATAATATAGAATTCATATTATACCAATGTTCTTCGAAAGCGAA
AAAAATTATCACCGAAAGAGGATATAAGCACAATGAGGTTGTCACACTAGAAGAGATTATAAAATATATTAAACCTTTTG
ATATAATTATAAACGATATATTAGATACGGATTCTAAATATATTGAAAAACTTATTTCGAAAGGTTGTTTTGTTGTCAAC
TTCGAAGACTTAGGAACTGGTGCAGATCAAGCTAATTTAGTAATTAATGCATTATATGAAAGATTTGATCCACCATTTTC
GCATAGATATGGATACAAATATGTATGTCTTAGAGATGATTTCCTTCTTCAAGCCCCCAATACTTTTTCTGATTGTGTCC
GGTCTGTATTGATAACTTTTGGTGGAGTTGATCCAACTGATCTAACTTTTCGCACCTTAAAAGCCCTCGAAAAAATTGAT
CCCAAAATCAATGTTAAATTAGTGATTGGCCCATCATATAGAGCTATAGACAAATTAGGACAATATATAAAGGAGCATTG
GGGTAATAGGAATCTTGAAGTTATGCGTAACGTAAAAAATATGGCAAAAGTGATGAGGAATGTTGACCTCGCTATTACTT
CAAATGGTAGAACTGTATATGAACTTGCTGCTATGAGAATCCCTATGATCAGCATAGCTCAGAACGATCGCGAAACGATG
CATCTGTTTGCAAGATACTCTGAAGGTATAAAGTACTTGGGAGTTTCTTGCAATGTCGACGAAGAAACAATCTACAAAAA
TGTTGTTGAGTTAATTAATGACTCAAGTAAGCGAAAAAAAATGTTTGATAATTTACCATATAAGGAAATAAGGCGAGGAA
TTTTTAATGTAACTGATCTGATTGAAAGCGAATACAGGAGGTGGAAGCATGAAAGAGATAGTAATAGGGAATTTTAA

Upstream 100 bases:

>100_bases
ACTTTATGCAAATAAGGAAAGGTGGTGTGAATTTGTCAAAATTCATACTTAGATTAGACACTCACAAAAGAAATTTCACT
GATGGTATGTGCGTTAGCAC

Downstream 100 bases:

>100_bases
GATTATTAAAGGTTCACTGGAAAAGCCCTACATTATTGCTGAGGCTGGTGTCAATCATGAGGGAGATATTGAAAAAGCAA
AGCTAATGATAATGCAAGCT

Product: N-acylneuraminate cytidylyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 558; Mature: 558

Protein sequence:

>558_residues
MWFDMLIAVIPARGGSKGIRRKNLRLLNAKPLISYVLEASIASRKIDAVIVTTDDYEIAEYCKQFNVIIRERPKHLGKDS
VPLDPVVSDSVQWFEEHYSANVETVITIQPTSPLITSSLIDEAIDNFFAQDLDSLISVVDNTHLGWKIENNELKPDYKKR
LNRQWLPKRFKETGAFVISKREIINSGTRIGGKVGIYEVPLEASIDLDSPNDWLLCSALLKRLSVKFVVTGNSNTGMGHI
YRTLTLADFWLGHNIEFILYQCSSKAKKIITERGYKHNEVVTLEEIIKYIKPFDIIINDILDTDSKYIEKLISKGCFVVN
FEDLGTGADQANLVINALYERFDPPFSHRYGYKYVCLRDDFLLQAPNTFSDCVRSVLITFGGVDPTDLTFRTLKALEKID
PKINVKLVIGPSYRAIDKLGQYIKEHWGNRNLEVMRNVKNMAKVMRNVDLAITSNGRTVYELAAMRIPMISIAQNDRETM
HLFARYSEGIKYLGVSCNVDEETIYKNVVELINDSSKRKKMFDNLPYKEIRRGIFNVTDLIESEYRRWKHERDSNREF

Sequences:

>Translated_558_residues
MWFDMLIAVIPARGGSKGIRRKNLRLLNAKPLISYVLEASIASRKIDAVIVTTDDYEIAEYCKQFNVIIRERPKHLGKDS
VPLDPVVSDSVQWFEEHYSANVETVITIQPTSPLITSSLIDEAIDNFFAQDLDSLISVVDNTHLGWKIENNELKPDYKKR
LNRQWLPKRFKETGAFVISKREIINSGTRIGGKVGIYEVPLEASIDLDSPNDWLLCSALLKRLSVKFVVTGNSNTGMGHI
YRTLTLADFWLGHNIEFILYQCSSKAKKIITERGYKHNEVVTLEEIIKYIKPFDIIINDILDTDSKYIEKLISKGCFVVN
FEDLGTGADQANLVINALYERFDPPFSHRYGYKYVCLRDDFLLQAPNTFSDCVRSVLITFGGVDPTDLTFRTLKALEKID
PKINVKLVIGPSYRAIDKLGQYIKEHWGNRNLEVMRNVKNMAKVMRNVDLAITSNGRTVYELAAMRIPMISIAQNDRETM
HLFARYSEGIKYLGVSCNVDEETIYKNVVELINDSSKRKKMFDNLPYKEIRRGIFNVTDLIESEYRRWKHERDSNREF
>Mature_558_residues
MWFDMLIAVIPARGGSKGIRRKNLRLLNAKPLISYVLEASIASRKIDAVIVTTDDYEIAEYCKQFNVIIRERPKHLGKDS
VPLDPVVSDSVQWFEEHYSANVETVITIQPTSPLITSSLIDEAIDNFFAQDLDSLISVVDNTHLGWKIENNELKPDYKKR
LNRQWLPKRFKETGAFVISKREIINSGTRIGGKVGIYEVPLEASIDLDSPNDWLLCSALLKRLSVKFVVTGNSNTGMGHI
YRTLTLADFWLGHNIEFILYQCSSKAKKIITERGYKHNEVVTLEEIIKYIKPFDIIINDILDTDSKYIEKLISKGCFVVN
FEDLGTGADQANLVINALYERFDPPFSHRYGYKYVCLRDDFLLQAPNTFSDCVRSVLITFGGVDPTDLTFRTLKALEKID
PKINVKLVIGPSYRAIDKLGQYIKEHWGNRNLEVMRNVKNMAKVMRNVDLAITSNGRTVYELAAMRIPMISIAQNDRETM
HLFARYSEGIKYLGVSCNVDEETIYKNVVELINDSSKRKKMFDNLPYKEIRRGIFNVTDLIESEYRRWKHERDSNREF

Specific function: Unknown

COG id: COG1083

COG function: function code M; CMP-N-acetylneuraminic acid synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 N-acetyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=218, Percent_Identity=34.4036697247706, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24667125, Length=175, Percent_Identity=27.4285714285714, Blast_Score=72, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR007235
- InterPro:   IPR020023 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF04101 Glyco_tran_28_C [H]

EC number: NA

Molecular weight: Translated: 64142; Mature: 64142

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWFDMLIAVIPARGGSKGIRRKNLRLLNAKPLISYVLEASIASRKIDAVIVTTDDYEIAE
CHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
YCKQFNVIIRERPKHLGKDSVPLDPVVSDSVQWFEEHYSANVETVITIQPTSPLITSSLI
HHHHHHHHHHHCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
DEAIDNFFAQDLDSLISVVDNTHLGWKIENNELKPDYKKRLNRQWLPKRFKETGAFVISK
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHCCHHHHHHHHHHCCCEEEEH
REIINSGTRIGGKVGIYEVPLEASIDLDSPNDWLLCSALLKRLSVKFVVTGNSNTGMGHI
HHHHCCCCCCCCEECEEECCCCCEECCCCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHH
YRTLTLADFWLGHNIEFILYQCSSKAKKIITERGYKHNEVVTLEEIIKYIKPFDIIINDI
HHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCCCCEEEHHHHHHHHCHHHHHHHHH
LDTDSKYIEKLISKGCFVVNFEDLGTGADQANLVINALYERFDPPFSHRYGYKYVCLRDD
HCCCHHHHHHHHHCCEEEEEEHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC
FLLQAPNTFSDCVRSVLITFGGVDPTDLTFRTLKALEKIDPKINVKLVIGPSYRAIDKLG
EEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
QYIKEHWGNRNLEVMRNVKNMAKVMRNVDLAITSNGRTVYELAAMRIPMISIAQNDRETM
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCEEEHHHHHHCCCCEECCCCHHHH
HLFARYSEGIKYLGVSCNVDEETIYKNVVELINDSSKRKKMFDNLPYKEIRRGIFNVTDL
HHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHH
IESEYRRWKHERDSNREF
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MWFDMLIAVIPARGGSKGIRRKNLRLLNAKPLISYVLEASIASRKIDAVIVTTDDYEIAE
CHHHHHHHHHCCCCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCCEEEEECCCHHHHH
YCKQFNVIIRERPKHLGKDSVPLDPVVSDSVQWFEEHYSANVETVITIQPTSPLITSSLI
HHHHHHHHHHHCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
DEAIDNFFAQDLDSLISVVDNTHLGWKIENNELKPDYKKRLNRQWLPKRFKETGAFVISK
HHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHCCHHHHHHHHHHCCCEEEEH
REIINSGTRIGGKVGIYEVPLEASIDLDSPNDWLLCSALLKRLSVKFVVTGNSNTGMGHI
HHHHCCCCCCCCEECEEECCCCCEECCCCCCCHHHHHHHHHHCCEEEEEECCCCCCHHHH
YRTLTLADFWLGHNIEFILYQCSSKAKKIITERGYKHNEVVTLEEIIKYIKPFDIIINDI
HHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHCCCCCCCEEEHHHHHHHHCHHHHHHHHH
LDTDSKYIEKLISKGCFVVNFEDLGTGADQANLVINALYERFDPPFSHRYGYKYVCLRDD
HCCCHHHHHHHHHCCEEEEEEHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECC
FLLQAPNTFSDCVRSVLITFGGVDPTDLTFRTLKALEKIDPKINVKLVIGPSYRAIDKLG
EEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHH
QYIKEHWGNRNLEVMRNVKNMAKVMRNVDLAITSNGRTVYELAAMRIPMISIAQNDRETM
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEECCCCEEEHHHHHHCCCCEECCCCHHHH
HLFARYSEGIKYLGVSCNVDEETIYKNVVELINDSSKRKKMFDNLPYKEIRRGIFNVTDL
HHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHH
IESEYRRWKHERDSNREF
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]