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The map label for this gene is 239617658

Identifier: 239617658

GI number: 239617658

Start: 1360478

End: 1361545

Strand: Reverse

Name: 239617658

Synonym: Kole_1281

Alternate gene names: NA

Gene position: 1361545-1360478 (Counterclockwise)

Preceding gene: 239617659

Following gene: 239617657

Centisome position: 59.14

GC content: 37.08

Gene sequence:

>1068_bases
ATGAAAGAGATAGTAATAGGGAATTTTAAGATTATTAAAGGTTCACTGGAAAAGCCCTACATTATTGCTGAGGCTGGTGT
CAATCATGAGGGAGATATTGAAAAAGCAAAGCTAATGATAATGCAAGCTTCTGAAGCTGGGGCTTCAGCAATTAAATTCC
AAACATACAAAGCCGAAAAACTTGCTTCGAAATACTCACCATCATATTGGAATACTAACAAGGAACCAACAAGAAGTCAG
TACGAGCTATTCAAGAAATACGATAAATTTTGGAAGAAAGAATACGAAGAGTTGGCAAATTACGCAGAGCAATGTGGCAT
AGATTTCCTTTCTACACCTTTTGACTTTGAATCTGCGGATTTTCTAGAACCATTGATGCCTGCCTACAAGGTCGCTTCTG
CAGATATAACAAACATTCCTTTTCTTAGACATATCGCTAGAAAAGGAAAGCCTATTCTTCTCTCAACTGGTGCTTCTACA
GTATCCGAAATATGGCAGGCTATTGAGGCTATAAAGGAAGAAGGAAATAACCAAATTGTCTTACTTCATTGTGTTTTGAA
TTATCCAACCCCAATAGAACGAGCAAATATAGGCATGATAAAAGACATGGTTAACAAGTTTCAAGACTATATTATCGGGT
ATTCCGACCACACGCTTCCAAATAAAATGGAAAAGGTTCTTACAGCAGCGTGGCTTCTTGGTGCACAAGTTATAGAAAAA
CATTTCACATTCGACAAAACATTGCCAGGGAACGACCATTATCACGCTATGGACAAAGAAGATTTAAGCCGTTTTGTTAA
GTTGTTGGATGAATACAAAGAATTTCTTGGCAATTTTGAAAAACACTATATAAAGGAAGAAGAAATTTCTAGACTTAATG
CGAGACGTAGTCTCGTAGCCAAAAGATTCATTCCTGCGGGCAAGATAATAGAAGAAACCGACATTGAAATAAAGAGACCA
GGAACAGGAGTTTCGCCTTTGCTATATGATAAAGTGATCGGTAGCAAGGCAACTAGAGATATAGGTGAAGATGAAATTCT
TCAATTTGGTGATTTTCGTATAGATTGA

Upstream 100 bases:

>100_bases
AAGCGAAAAAAAATGTTTGATAATTTACCATATAAGGAAATAAGGCGAGGAATTTTTAATGTAACTGATCTGATTGAAAG
CGAATACAGGAGGTGGAAGC

Downstream 100 bases:

>100_bases
TTACTTTTGGCAATATAAAATTTAGTTCTTGAATGTAAAAAGTCAATAGGATTTTGGTTCTTCCGAAAAGTATATAAATC
AGAGTGTGAGAACCTTCGGC

Product: N-acylneuraminate-9-phosphate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 355

Protein sequence:

>355_residues
MKEIVIGNFKIIKGSLEKPYIIAEAGVNHEGDIEKAKLMIMQASEAGASAIKFQTYKAEKLASKYSPSYWNTNKEPTRSQ
YELFKKYDKFWKKEYEELANYAEQCGIDFLSTPFDFESADFLEPLMPAYKVASADITNIPFLRHIARKGKPILLSTGAST
VSEIWQAIEAIKEEGNNQIVLLHCVLNYPTPIERANIGMIKDMVNKFQDYIIGYSDHTLPNKMEKVLTAAWLLGAQVIEK
HFTFDKTLPGNDHYHAMDKEDLSRFVKLLDEYKEFLGNFEKHYIKEEEISRLNARRSLVAKRFIPAGKIIEETDIEIKRP
GTGVSPLLYDKVIGSKATRDIGEDEILQFGDFRID

Sequences:

>Translated_355_residues
MKEIVIGNFKIIKGSLEKPYIIAEAGVNHEGDIEKAKLMIMQASEAGASAIKFQTYKAEKLASKYSPSYWNTNKEPTRSQ
YELFKKYDKFWKKEYEELANYAEQCGIDFLSTPFDFESADFLEPLMPAYKVASADITNIPFLRHIARKGKPILLSTGAST
VSEIWQAIEAIKEEGNNQIVLLHCVLNYPTPIERANIGMIKDMVNKFQDYIIGYSDHTLPNKMEKVLTAAWLLGAQVIEK
HFTFDKTLPGNDHYHAMDKEDLSRFVKLLDEYKEFLGNFEKHYIKEEEISRLNARRSLVAKRFIPAGKIIEETDIEIKRP
GTGVSPLLYDKVIGSKATRDIGEDEILQFGDFRID
>Mature_355_residues
MKEIVIGNFKIIKGSLEKPYIIAEAGVNHEGDIEKAKLMIMQASEAGASAIKFQTYKAEKLASKYSPSYWNTNKEPTRSQ
YELFKKYDKFWKKEYEELANYAEQCGIDFLSTPFDFESADFLEPLMPAYKVASADITNIPFLRHIARKGKPILLSTGAST
VSEIWQAIEAIKEEGNNQIVLLHCVLNYPTPIERANIGMIKDMVNKFQDYIIGYSDHTLPNKMEKVLTAAWLLGAQVIEK
HFTFDKTLPGNDHYHAMDKEDLSRFVKLLDEYKEFLGNFEKHYIKEEEISRLNARRSLVAKRFIPAGKIIEETDIEIKRP
GTGVSPLLYDKVIGSKATRDIGEDEILQFGDFRID

Specific function: Unknown

COG id: COG2089

COG function: function code M; Sialic acid synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To B.subtilis spsE [H]

Homologues:

Organism=Homo sapiens, GI12056473, Length=337, Percent_Identity=31.7507418397626, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI21357081, Length=364, Percent_Identity=29.6703296703297, Blast_Score=158, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006190
- InterPro:   IPR013785
- InterPro:   IPR013132
- InterPro:   IPR013974 [H]

Pfam domain/function: PF03102 NeuB; PF08666 SAF [H]

EC number: NA

Molecular weight: Translated: 40598; Mature: 40598

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50844 AFP_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEIVIGNFKIIKGSLEKPYIIAEAGVNHEGDIEKAKLMIMQASEAGASAIKFQTYKAEK
CCCEEECCEEEEECCCCCCEEEEECCCCCCCCHHHHHEEEEECCCCCCCHHEEHHHHHHH
LASKYSPSYWNTNKEPTRSQYELFKKYDKFWKKEYEELANYAEQCGIDFLSTPFDFESAD
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHH
FLEPLMPAYKVASADITNIPFLRHIARKGKPILLSTGASTVSEIWQAIEAIKEEGNNQIV
HHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEEE
LLHCVLNYPTPIERANIGMIKDMVNKFQDYIIGYSDHTLPNKMEKVLTAAWLLGAQVIEK
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
HFTFDKTLPGNDHYHAMDKEDLSRFVKLLDEYKEFLGNFEKHYIKEEEISRLNARRSLVA
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KRFIPAGKIIEETDIEIKRPGTGVSPLLYDKVIGSKATRDIGEDEILQFGDFRID
HHHCCCCCCEECCCCEEECCCCCCCHHHHHHHHCCHHHHCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MKEIVIGNFKIIKGSLEKPYIIAEAGVNHEGDIEKAKLMIMQASEAGASAIKFQTYKAEK
CCCEEECCEEEEECCCCCCEEEEECCCCCCCCHHHHHEEEEECCCCCCCHHEEHHHHHHH
LASKYSPSYWNTNKEPTRSQYELFKKYDKFWKKEYEELANYAEQCGIDFLSTPFDFESAD
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCCCCCCCHH
FLEPLMPAYKVASADITNIPFLRHIARKGKPILLSTGASTVSEIWQAIEAIKEEGNNQIV
HHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHCCCCEEE
LLHCVLNYPTPIERANIGMIKDMVNKFQDYIIGYSDHTLPNKMEKVLTAAWLLGAQVIEK
EEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
HFTFDKTLPGNDHYHAMDKEDLSRFVKLLDEYKEFLGNFEKHYIKEEEISRLNARRSLVA
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KRFIPAGKIIEETDIEIKRPGTGVSPLLYDKVIGSKATRDIGEDEILQFGDFRID
HHHCCCCCCEECCCCEEECCCCCCCHHHHHHHHCCHHHHCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]