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The map label for this gene is ppa [H]

Identifier: 239617516

GI number: 239617516

Start: 1198287

End: 1198781

Strand: Direct

Name: ppa [H]

Synonym: Kole_1132

Alternate gene names: 239617516

Gene position: 1198287-1198781 (Clockwise)

Preceding gene: 239617505

Following gene: 239617519

Centisome position: 52.05

GC content: 39.39

Gene sequence:

>495_bases
ATGGTTGTTACAGTGATGGTTGAAATTCCCAAAGGTAGCAGAAACAAGTATGAATATGACAAAGAAAAGAAAATGATTCG
ATTCGATAGAACTCTTTTCTCATCTGTTCATTATCCAGCTGACTATGGGTTCATTTGCGATACGCTTGCGTTAGATGGAG
ATCCGCTTGATGCCATGGTTCTTGTTTCAGAACCAACCTTCCCCGGGTGCATTATAGATGTAGTCCCAGTTGGTGTTTTC
AAGATGTGGGACGAAAAAGGAACTGATGAAAAGATATTATGTGTTCCCGTGAAAGATCCTCTCTGGAATCATATTGAGAA
TCTAGAGCAAGTTCCGCCACACCTCCTTAGAGAGATAGAAAACTTTTTCTCTATTTACAAACAACTTGAAAACAAGGTCA
CTGGTACCGAAGGTTGGGAAAGAAGAGAAGCTGCTGAAAGGATAATAGAAGAAGCTCAAAGACGCTATCAAGAAGTGAAG
AAAAAGAATAAGTAA

Upstream 100 bases:

>100_bases
GACGGAAAGAATTGAGAATTTTTGATCGATTTGTTTATCGAGCTTTCTAGTGTTAAAATGGCACAATGAAAAGAGATTTT
GAAATCGGGAGGAGATATCA

Downstream 100 bases:

>100_bases
CGCTTTTGCGTCTATCGGTCTTTATCTTGGTGCAGTTCGTATGTACGCTTTACTTCATCCAGAACATCAAAAAACGCATC
AAGAACAACAGGATCAAATC

Product: Inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 164; Mature: 164

Protein sequence:

>164_residues
MVVTVMVEIPKGSRNKYEYDKEKKMIRFDRTLFSSVHYPADYGFICDTLALDGDPLDAMVLVSEPTFPGCIIDVVPVGVF
KMWDEKGTDEKILCVPVKDPLWNHIENLEQVPPHLLREIENFFSIYKQLENKVTGTEGWERREAAERIIEEAQRRYQEVK
KKNK

Sequences:

>Translated_164_residues
MVVTVMVEIPKGSRNKYEYDKEKKMIRFDRTLFSSVHYPADYGFICDTLALDGDPLDAMVLVSEPTFPGCIIDVVPVGVF
KMWDEKGTDEKILCVPVKDPLWNHIENLEQVPPHLLREIENFFSIYKQLENKVTGTEGWERREAAERIIEEAQRRYQEVK
KKNK
>Mature_164_residues
MVVTVMVEIPKGSRNKYEYDKEKKMIRFDRTLFSSVHYPADYGFICDTLALDGDPLDAMVLVSEPTFPGCIIDVVPVGVF
KMWDEKGTDEKILCVPVKDPLWNHIENLEQVPPHLLREIENFFSIYKQLENKVTGTEGWERREAAERIIEEAQRRYQEVK
KKNK

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=157, Percent_Identity=40.7643312101911, Blast_Score=110, Evalue=4e-26,
Organism=Saccharomyces cerevisiae, GI6319483, Length=188, Percent_Identity=26.063829787234, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19151; Mature: 19151

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVTVMVEIPKGSRNKYEYDKEKKMIRFDRTLFSSVHYPADYGFICDTLALDGDPLDAMV
CEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEE
LVSEPTFPGCIIDVVPVGVFKMWDEKGTDEKILCVPVKDPLWNHIENLEQVPPHLLREIE
EEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHH
NFFSIYKQLENKVTGTEGWERREAAERIIEEAQRRYQEVKKKNK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVVTVMVEIPKGSRNKYEYDKEKKMIRFDRTLFSSVHYPADYGFICDTLALDGDPLDAMV
CEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCEEE
LVSEPTFPGCIIDVVPVGVFKMWDEKGTDEKILCVPVKDPLWNHIENLEQVPPHLLREIE
EEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHH
NFFSIYKQLENKVTGTEGWERREAAERIIEEAQRRYQEVKKKNK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]