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The map label for this gene is ahpC [C]

Identifier: 239617505

GI number: 239617505

Start: 1190597

End: 1191241

Strand: Direct

Name: ahpC [C]

Synonym: Kole_1121

Alternate gene names: 239617505

Gene position: 1190597-1191241 (Clockwise)

Preceding gene: 239617500

Following gene: 239617516

Centisome position: 51.72

GC content: 41.4

Gene sequence:

>645_bases
ATGGAAGAAAGAATCCCATTGATAGGTGAAAAATTTCCGGAACTAAAAGTCCAAACAACACATGGAGTTATGAAGCTTCC
GGACGCTTTCAAAGGCAAATGGTTCATTCTCTTCAGCCATCCTGCTGATTTTACACCGGTTTGTACGACCGAATTTGTTG
CTTTCCAAAAGCGATACGATGAGTTCAAAAAGCTAAACACTGAATTAATAGGTTTGAGCATTGACCAGGTGTTCTCCCAC
ATTAAATGGGTTGAATGGATCAAGGACAATCTTAATGTAGAGATTAAATTCCCTGTAATCGCTGATGATACTGGTAAAGT
TGCTTCCAAGCTTGGGCTAATCCATCCCGGAAAAGGGACGAATACTGTCAGGGCTGTTTTTATCGTTGATCCAGAAGGAA
CCATCCGTGCTATACTTTACTACCCGCAGGAGCTTGGCAGAAACGTTGACGAAATCTTAAGAATGATCAAAGGATTCCAG
GTTTCTGACGATAAGGGCGTTGCTATTCCTGCAAATTGGCCCAACAACGAGCTTATTGGTGATGAGGTTATTATTCCACC
TGCAAGCGACATGGAAACTGCAGAAAAGAGAAAAGAAGAATATCAGTGCTTCGATTGGTGGTTTTGCCACAAAAAAGTTG
ATTAA

Upstream 100 bases:

>100_bases
AATTCGGTTTCTTGACTTTTATGGAAGAAAAGTAGTATAATAAATGTAGCAATTTAGATGTGTTATAAATTGTAACAAAC
AAAATTGGAGGTGAGTTTAT

Downstream 100 bases:

>100_bases
TTGACTTCAATTGCCCCCTATATCAAAAAGCACAGTTAAGGCGAGGATTTATTCCTCGCCTTTTCTATTTCTTAACCTGT
TGTATTTTTCCTTAAATTCC

Product: Peroxiredoxin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 214; Mature: 214

Protein sequence:

>214_residues
MEERIPLIGEKFPELKVQTTHGVMKLPDAFKGKWFILFSHPADFTPVCTTEFVAFQKRYDEFKKLNTELIGLSIDQVFSH
IKWVEWIKDNLNVEIKFPVIADDTGKVASKLGLIHPGKGTNTVRAVFIVDPEGTIRAILYYPQELGRNVDEILRMIKGFQ
VSDDKGVAIPANWPNNELIGDEVIIPPASDMETAEKRKEEYQCFDWWFCHKKVD

Sequences:

>Translated_214_residues
MEERIPLIGEKFPELKVQTTHGVMKLPDAFKGKWFILFSHPADFTPVCTTEFVAFQKRYDEFKKLNTELIGLSIDQVFSH
IKWVEWIKDNLNVEIKFPVIADDTGKVASKLGLIHPGKGTNTVRAVFIVDPEGTIRAILYYPQELGRNVDEILRMIKGFQ
VSDDKGVAIPANWPNNELIGDEVIIPPASDMETAEKRKEEYQCFDWWFCHKKVD
>Mature_214_residues
MEERIPLIGEKFPELKVQTTHGVMKLPDAFKGKWFILFSHPADFTPVCTTEFVAFQKRYDEFKKLNTELIGLSIDQVFSH
IKWVEWIKDNLNVEIKFPVIADDTGKVASKLGLIHPGKGTNTVRAVFIVDPEGTIRAILYYPQELGRNVDEILRMIKGFQ
VSDDKGVAIPANWPNNELIGDEVIIPPASDMETAEKRKEEYQCFDWWFCHKKVD

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=200, Percent_Identity=39, Blast_Score=127, Evalue=7e-30,
Organism=Homo sapiens, GI5453549, Length=175, Percent_Identity=36, Blast_Score=119, Evalue=2e-27,
Organism=Homo sapiens, GI32189392, Length=178, Percent_Identity=35.3932584269663, Blast_Score=116, Evalue=1e-26,
Organism=Homo sapiens, GI5802974, Length=147, Percent_Identity=37.4149659863946, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI32483377, Length=147, Percent_Identity=37.4149659863946, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI4505591, Length=156, Percent_Identity=37.8205128205128, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI32455266, Length=156, Percent_Identity=37.8205128205128, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI32455264, Length=156, Percent_Identity=37.8205128205128, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI33188454, Length=82, Percent_Identity=42.6829268292683, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1786822, Length=148, Percent_Identity=34.4594594594595, Blast_Score=91, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17554494, Length=145, Percent_Identity=40, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI25153706, Length=170, Percent_Identity=37.0588235294118, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI32565831, Length=179, Percent_Identity=35.7541899441341, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI193204376, Length=179, Percent_Identity=35.7541899441341, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319407, Length=198, Percent_Identity=41.4141414141414, Blast_Score=145, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6323613, Length=147, Percent_Identity=33.3333333333333, Blast_Score=94, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6320661, Length=145, Percent_Identity=34.4827586206897, Blast_Score=93, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17975518, Length=198, Percent_Identity=39.3939393939394, Blast_Score=136, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24652434, Length=199, Percent_Identity=40.2010050251256, Blast_Score=135, Evalue=1e-32,
Organism=Drosophila melanogaster, GI24652436, Length=198, Percent_Identity=38.8888888888889, Blast_Score=135, Evalue=3e-32,
Organism=Drosophila melanogaster, GI24581278, Length=172, Percent_Identity=41.2790697674419, Blast_Score=129, Evalue=1e-30,
Organism=Drosophila melanogaster, GI17738015, Length=155, Percent_Identity=41.2903225806452, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24656348, Length=158, Percent_Identity=36.0759493670886, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI17864676, Length=158, Percent_Identity=36.0759493670886, Blast_Score=114, Evalue=7e-26,
Organism=Drosophila melanogaster, GI21357347, Length=173, Percent_Identity=35.8381502890173, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI17157991, Length=151, Percent_Identity=38.4105960264901, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24641739, Length=151, Percent_Identity=38.4105960264901, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24598; Mature: 24598

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEERIPLIGEKFPELKVQTTHGVMKLPDAFKGKWFILFSHPADFTPVCTTEFVAFQKRYD
CCCCCCCCCCCCCCEEEEECCCEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
EFKKLNTELIGLSIDQVFSHIKWVEWIKDNLNVEIKFPVIADDTGKVASKLGLIHPGKGT
HHHHCCHHHEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHCCCCCCCCC
NTVRAVFIVDPEGTIRAILYYPQELGRNVDEILRMIKGFQVSDDKGVAIPANWPNNELIG
CEEEEEEEECCCCCEEEEEECCHHHCCCHHHHHHHHHCCEECCCCCEEEECCCCCCCCCC
DEVIIPPASDMETAEKRKEEYQCFDWWFCHKKVD
CEEEECCCCCHHHHHHHHHHCCHHEEEEEEECCC
>Mature Secondary Structure
MEERIPLIGEKFPELKVQTTHGVMKLPDAFKGKWFILFSHPADFTPVCTTEFVAFQKRYD
CCCCCCCCCCCCCCEEEEECCCEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHH
EFKKLNTELIGLSIDQVFSHIKWVEWIKDNLNVEIKFPVIADDTGKVASKLGLIHPGKGT
HHHHCCHHHEEEEHHHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHCCCCCCCCC
NTVRAVFIVDPEGTIRAILYYPQELGRNVDEILRMIKGFQVSDDKGVAIPANWPNNELIG
CEEEEEEEECCCCCEEEEEECCHHHCCCHHHHHHHHHCCEECCCCCEEEECCCCCCCCCC
DEVIIPPASDMETAEKRKEEYQCFDWWFCHKKVD
CEEEECCCCCHHHHHHHHHHCCHHEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]