| Definition | Kosmotoga olearia TBF 19.5.1, complete genome. |
|---|---|
| Accession | NC_012785 |
| Length | 2,302,126 |
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The map label for this gene is braF [H]
Identifier: 239617489
GI number: 239617489
Start: 1173719
End: 1174558
Strand: Direct
Name: braF [H]
Synonym: Kole_1105
Alternate gene names: 239617489
Gene position: 1173719-1174558 (Clockwise)
Preceding gene: 239617488
Following gene: 239617490
Centisome position: 50.98
GC content: 42.98
Gene sequence:
>840_bases ATGAGTAAACTGTTAGAACTTAATCACGTAACCATGAAGTTTGGTGGGCTTGTTGCCGTAAATGATTTCGATAATTACAT TGAAGAAGGAGAAATTCTCGGCTTGATTGGCCCCAATGGTGCAGGAAAAACAACTGTGTTCAATGTGATCACAGGTGTTT ATGTTCCAACAGAAGGGCGAATAATCTTTAATGGTGTGGATATCACACCTTTTAAGCCTCACCAGATCACGCATCTTGGC ATTGCTAGAACGTTCCAGAACATAAGGTTGTTTGAAGAAATGACCGTTCTGGAAAATGTTATGGTGGCCCAGCATCACGA GCTTGCTACGACAGATGCTGAAAAATTGTTGCGGCAAGCAGGTAGGGAACCTTACGGTGCTGGTGGGATGTGGTTCTGGA AAGCTGTTTTGAGATTGGGTTATCTAGACAAAGAAAAAAGCATAATGAAAAAATCAATGGAGCTCTTAGAACGGATGGGA TTGGCGGAATTTGCAAACGAAAAAGCGAGTTCTCTTCCATACGGTGCACAACGGCTTTTGGAAATTGCAAGGGCTTTAGC AACTGATGCAAAACTTCTCTTGCTGGACGAGCCTGCCGCCGGAATGAATCCATCCGAAAGTCATGATTTGATGAATATGA TCCGGAAAATCCGGGACGAATTTGGTGTTACTATTTTCCTTATAGAACATGATATGAAAGTCGTCATGGGATTGTGTGAA CGTATTTTAGTCATGGATTACGGAAAACTCATCGCAAACGGAACACCCGAAGAGGTTCAGAAGAATCCGAAAGTAATAGA GGCTTATCTCGGGGAGGAATGGCAGAATGTCGGAACGTGA
Upstream 100 bases:
>100_bases GTAATCGTGATGATCTTCTGGCCACGCGGCATAATGGGAAAAAATGAGTTGACATGGAATAATCTGTACAACTGGATCTT TAGAAAAAAGGGTGAAGCCA
Downstream 100 bases:
>100_bases TTTCTTATTGACAATAGAAGATCTCAGGGTAAACTATGGAGCAATAAAAGCTTTGAAAGGTATAAGCCTCAACGTTCCCC AAGGGAAAATAGTTACATTG
Product: ABC transporter related
Products: ADP; phosphate; L-valine [Cytoplasm]; ADP; L-iso-leucine [Cytoplasm]; L-leucine [Cytoplasm] [C]
Alternate protein names: NA
Number of amino acids: Translated: 279; Mature: 278
Protein sequence:
>279_residues MSKLLELNHVTMKFGGLVAVNDFDNYIEEGEILGLIGPNGAGKTTVFNVITGVYVPTEGRIIFNGVDITPFKPHQITHLG IARTFQNIRLFEEMTVLENVMVAQHHELATTDAEKLLRQAGREPYGAGGMWFWKAVLRLGYLDKEKSIMKKSMELLERMG LAEFANEKASSLPYGAQRLLEIARALATDAKLLLLDEPAAGMNPSESHDLMNMIRKIRDEFGVTIFLIEHDMKVVMGLCE RILVMDYGKLIANGTPEEVQKNPKVIEAYLGEEWQNVGT
Sequences:
>Translated_279_residues MSKLLELNHVTMKFGGLVAVNDFDNYIEEGEILGLIGPNGAGKTTVFNVITGVYVPTEGRIIFNGVDITPFKPHQITHLG IARTFQNIRLFEEMTVLENVMVAQHHELATTDAEKLLRQAGREPYGAGGMWFWKAVLRLGYLDKEKSIMKKSMELLERMG LAEFANEKASSLPYGAQRLLEIARALATDAKLLLLDEPAAGMNPSESHDLMNMIRKIRDEFGVTIFLIEHDMKVVMGLCE RILVMDYGKLIANGTPEEVQKNPKVIEAYLGEEWQNVGT >Mature_278_residues SKLLELNHVTMKFGGLVAVNDFDNYIEEGEILGLIGPNGAGKTTVFNVITGVYVPTEGRIIFNGVDITPFKPHQITHLGI ARTFQNIRLFEEMTVLENVMVAQHHELATTDAEKLLRQAGREPYGAGGMWFWKAVLRLGYLDKEKSIMKKSMELLERMGL AEFANEKASSLPYGAQRLLEIARALATDAKLLLLDEPAAGMNPSESHDLMNMIRKIRDEFGVTIFLIEHDMKVVMGLCER ILVMDYGKLIANGTPEEVQKNPKVIEAYLGEEWQNVGT
Specific function: Component of the high affinity leucine, isoleucine, valine, transport system (LIV-I), which is operative without Na(+) and is specific for alanine and threonine, in addition to branched-chain amino acids [H]
COG id: COG0411
COG function: function code E; ABC-type branched-chain amino acid transport systems, ATPase component
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI105990541, Length=241, Percent_Identity=28.6307053941909, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI30795238, Length=250, Percent_Identity=27.2, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI27881501, Length=250, Percent_Identity=27.2, Blast_Score=85, Evalue=7e-17, Organism=Homo sapiens, GI21536376, Length=242, Percent_Identity=28.099173553719, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI45446740, Length=239, Percent_Identity=26.7782426778243, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI47078218, Length=239, Percent_Identity=26.7782426778243, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI153792144, Length=243, Percent_Identity=24.6913580246914, Blast_Score=69, Evalue=4e-12, Organism=Escherichia coli, GI1789864, Length=269, Percent_Identity=46.8401486988848, Blast_Score=242, Evalue=2e-65, Organism=Escherichia coli, GI1789593, Length=271, Percent_Identity=29.8892988929889, Blast_Score=121, Evalue=5e-29, Organism=Escherichia coli, GI87082268, Length=268, Percent_Identity=30.2238805970149, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI1790525, Length=263, Percent_Identity=28.1368821292776, Blast_Score=117, Evalue=7e-28, Organism=Escherichia coli, GI1787029, Length=261, Percent_Identity=28.3524904214559, Blast_Score=114, Evalue=5e-27, Organism=Escherichia coli, GI1787370, Length=274, Percent_Identity=29.1970802919708, Blast_Score=114, Evalue=1e-26, Organism=Escherichia coli, GI87081791, Length=263, Percent_Identity=28.8973384030418, Blast_Score=112, Evalue=2e-26, Organism=Escherichia coli, GI48995001, Length=238, Percent_Identity=29.4117647058824, Blast_Score=112, Evalue=3e-26, Organism=Escherichia coli, GI1786398, Length=267, Percent_Identity=27.3408239700375, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI87081709, Length=271, Percent_Identity=25.0922509225092, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI1788761, Length=270, Percent_Identity=25.9259259259259, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI1790544, Length=274, Percent_Identity=24.8175182481752, Blast_Score=107, Evalue=8e-25, Organism=Escherichia coli, GI1789991, Length=255, Percent_Identity=29.8039215686275, Blast_Score=106, Evalue=1e-24, Organism=Escherichia coli, GI87081782, Length=275, Percent_Identity=28.3636363636364, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1789032, Length=262, Percent_Identity=28.6259541984733, Blast_Score=104, Evalue=8e-24, Organism=Escherichia coli, GI1790190, Length=252, Percent_Identity=26.984126984127, Blast_Score=102, Evalue=3e-23, Organism=Escherichia coli, GI1788210, Length=279, Percent_Identity=26.1648745519713, Blast_Score=100, Evalue=9e-23, Organism=Escherichia coli, GI48994943, Length=256, Percent_Identity=28.515625, Blast_Score=98, Evalue=5e-22, Organism=Escherichia coli, GI1788472, Length=249, Percent_Identity=23.6947791164659, Blast_Score=94, Evalue=1e-20, Organism=Escherichia coli, GI1786345, Length=257, Percent_Identity=25.2918287937743, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1786872, Length=266, Percent_Identity=25.5639097744361, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1788225, Length=269, Percent_Identity=26.0223048327138, Blast_Score=93, Evalue=2e-20, Organism=Escherichia coli, GI1787712, Length=265, Percent_Identity=24.1509433962264, Blast_Score=92, Evalue=5e-20, Organism=Escherichia coli, GI1789672, Length=268, Percent_Identity=22.7611940298507, Blast_Score=91, Evalue=6e-20, Organism=Escherichia coli, GI1788450, Length=262, Percent_Identity=26.7175572519084, Blast_Score=91, Evalue=1e-19, Organism=Escherichia coli, GI1786319, Length=256, Percent_Identity=28.125, Blast_Score=89, Evalue=3e-19, Organism=Escherichia coli, GI1787792, Length=268, Percent_Identity=26.1194029850746, Blast_Score=88, Evalue=7e-19, Organism=Escherichia coli, GI1790739, Length=255, Percent_Identity=25.0980392156863, Blast_Score=84, Evalue=7e-18, Organism=Escherichia coli, GI1787500, Length=251, Percent_Identity=27.8884462151394, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1787089, Length=255, Percent_Identity=24.7058823529412, Blast_Score=82, Evalue=3e-17, Organism=Escherichia coli, GI48994883, Length=258, Percent_Identity=25.968992248062, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI1789891, Length=233, Percent_Identity=22.7467811158798, Blast_Score=82, Evalue=5e-17, Organism=Escherichia coli, GI1786803, Length=251, Percent_Identity=22.3107569721116, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1789873, Length=250, Percent_Identity=25.2, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI1789962, Length=245, Percent_Identity=23.265306122449, Blast_Score=80, Evalue=2e-16, Organism=Escherichia coli, GI145693107, Length=260, Percent_Identity=28.0769230769231, Blast_Score=79, Evalue=3e-16, Organism=Escherichia coli, GI1789586, Length=267, Percent_Identity=25.0936329588015, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1787548, Length=275, Percent_Identity=25.0909090909091, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI48994997, Length=261, Percent_Identity=23.7547892720307, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI1787758, Length=274, Percent_Identity=20.4379562043796, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1788897, Length=246, Percent_Identity=22.7642276422764, Blast_Score=74, Evalue=9e-15, Organism=Escherichia coli, GI1788644, Length=235, Percent_Identity=26.8085106382979, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1787105, Length=240, Percent_Identity=24.1666666666667, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI1787041, Length=248, Percent_Identity=27.4193548387097, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1786981, Length=282, Percent_Identity=24.822695035461, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1787143, Length=259, Percent_Identity=22.7799227799228, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17510237, Length=260, Percent_Identity=26.9230769230769, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI71983523, Length=233, Percent_Identity=29.1845493562232, Blast_Score=94, Evalue=6e-20, Organism=Caenorhabditis elegans, GI71983516, Length=233, Percent_Identity=29.1845493562232, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI71983510, Length=233, Percent_Identity=29.1845493562232, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI115533608, Length=246, Percent_Identity=28.8617886178862, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI71992290, Length=243, Percent_Identity=27.1604938271605, Blast_Score=77, Evalue=1e-14, Organism=Drosophila melanogaster, GI24648314, Length=259, Percent_Identity=26.2548262548263, Blast_Score=91, Evalue=9e-19,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR003593 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 31209; Mature: 31078
Theoretical pI: Translated: 5.23; Mature: 5.23
Prosite motif: PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 5.0 %Met (Translated Protein) 5.4 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 4.7 %Met (Mature Protein) 5.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSKLLELNHVTMKFGGLVAVNDFDNYIEEGEILGLIGPNGAGKTTVFNVITGVYVPTEGR CCCHHHHHHHEEEECCEEEECCHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCEECCCCE IIFNGVDITPFKPHQITHLGIARTFQNIRLFEEMTVLENVMVAQHHELATTDAEKLLRQA EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH GREPYGAGGMWFWKAVLRLGYLDKEKSIMKKSMELLERMGLAEFANEKASSLPYGAQRLL CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCHHHCCCHHHHHHH EIARALATDAKLLLLDEPAAGMNPSESHDLMNMIRKIRDEFGVTIFLIEHDMKVVMGLCE HHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHH RILVMDYGKLIANGTPEEVQKNPKVIEAYLGEEWQNVGT HHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCC >Mature Secondary Structure SKLLELNHVTMKFGGLVAVNDFDNYIEEGEILGLIGPNGAGKTTVFNVITGVYVPTEGR CCHHHHHHHEEEECCEEEECCHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCEECCCCE IIFNGVDITPFKPHQITHLGIARTFQNIRLFEEMTVLENVMVAQHHELATTDAEKLLRQA EEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH GREPYGAGGMWFWKAVLRLGYLDKEKSIMKKSMELLERMGLAEFANEKASSLPYGAQRLL CCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHCCHHHCCCHHHHHHH EIARALATDAKLLLLDEPAAGMNPSESHDLMNMIRKIRDEFGVTIFLIEHDMKVVMGLCE HHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCEEEEEEECCHHHHHHHHH RILVMDYGKLIANGTPEEVQKNPKVIEAYLGEEWQNVGT HHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: ATP; L-valine [Periplasm]; H2O; ATP; L-iso-leucine [Periplasm]; L-leucine [Periplasm] [C]
Specific reaction: ATP + L-valine [Periplasm] + H2O = ADP + phosphate + L-valine [Cytoplasm] ATP + L-iso-leucine [Periplasm] + H2O = ADP + phosphate + L-iso-leucine [Cytoplasm] ATP + L-leucine [Periplasm] + H2O = ADP + phosphate + L-leucine [Cytoplasm] [C]
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 2120183; 10984043 [H]