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The map label for this gene is iolC [H]

Identifier: 239617455

GI number: 239617455

Start: 1138822

End: 1139754

Strand: Reverse

Name: iolC [H]

Synonym: Kole_1070

Alternate gene names: 239617455

Gene position: 1139754-1138822 (Counterclockwise)

Preceding gene: 239617456

Following gene: 239617454

Centisome position: 49.51

GC content: 38.59

Gene sequence:

>933_bases
ATGAAAAAGATTTTAATAATTGGCGAACTGCTCATCGACTTGATTTCCGAAGAGTATGTGGATGATCTTGCTGATGCAAA
AAGTTTTAAAAAATATTATGCTGGCTCTCCAGGAAACTTGGCGATAAATCTTAAGAATCTCGGCATTGAACCATTGTTAC
TTGCTTCAGTAGGAGATGACCCTTTTGGAAGAGGCTACAAAAAATGGTTAGAAGAAAAAGGGATTAAAACTACCTTTATA
AACCAAAGCAAGCTTCCCACAAGTTTTGTCATAGTTTCAAAATCCCAAGATACTCCACTATTTATGCCAATTAGGGGCGC
AGATTACAAAATAGAATTTCCTCAAGAGCCTGAGAAGCTCTTTGAAGGAGTTGAGTTTATTCACCTGACGAGTTGGCCGC
TTTCTCGTAATCCAGCCCGGAAAACCGTTATGAAAGTGCTTGAAATAGCAAAAAAAAGAGGTACAAAAGTATGTTTTGAC
CCAAATTATCGAGAAATCCTGTGGGAAAACGGTTCTGACGGTAAAACTTTTATAAGAGAATTCATGAAAGACATTTATTT
GGTAAAACCTTCCTTAGATGATTCCTTTCATATCTTTGGAAAAATGTCGCCTCGAAGATACATAAATGAATATCACAAAT
GTGGTGTCGAAAATGTCGTTCTCACCTTGGGCAAAGACGGTGTCTTGGTTTCTGATGGAGAAAAAGTAAAAAAAATCCAT
ACGTACGCTAAAAATGTTGTTGATACCACTGGGGCTGGAGATGCTTTTTGGAGTGGTTTGTATCACGGATTATTGAAGGG
CTTCGACGTTTTCGGGGCCGCTAAAATAGGGAATGCCGCCGCTGCCTTTAGGTTGGAAACGGAAGATAAATCAGTCCCTA
TTCCTTCTATTGAAGTACTAAAAAAAATCATGGAAACGAGGTCGATCTCATGA

Upstream 100 bases:

>100_bases
TGATGACAGCCCCGGTGTTAATGCTCTTCGTTGCGCTTCAAGGGCAGTATGTAAAGAGCATTTCTCAGACAGGAATAAAA
TAAGTTTGTGTGGTGGTGCT

Downstream 100 bases:

>100_bases
AAATTGCCTTTTTAAATCCACAGGGGAACTTTGATTCCCTCGATAGTCATTGGACAGACCACCCCGATTTCGGCGGACAG
CTCGTATATGTAAAAGAGTT

Product: PfkB domain protein

Products: NA

Alternate protein names: 2-deoxy-5-keto-D-gluconate kinase; DKG kinase [H]

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MKKILIIGELLIDLISEEYVDDLADAKSFKKYYAGSPGNLAINLKNLGIEPLLLASVGDDPFGRGYKKWLEEKGIKTTFI
NQSKLPTSFVIVSKSQDTPLFMPIRGADYKIEFPQEPEKLFEGVEFIHLTSWPLSRNPARKTVMKVLEIAKKRGTKVCFD
PNYREILWENGSDGKTFIREFMKDIYLVKPSLDDSFHIFGKMSPRRYINEYHKCGVENVVLTLGKDGVLVSDGEKVKKIH
TYAKNVVDTTGAGDAFWSGLYHGLLKGFDVFGAAKIGNAAAAFRLETEDKSVPIPSIEVLKKIMETRSIS

Sequences:

>Translated_310_residues
MKKILIIGELLIDLISEEYVDDLADAKSFKKYYAGSPGNLAINLKNLGIEPLLLASVGDDPFGRGYKKWLEEKGIKTTFI
NQSKLPTSFVIVSKSQDTPLFMPIRGADYKIEFPQEPEKLFEGVEFIHLTSWPLSRNPARKTVMKVLEIAKKRGTKVCFD
PNYREILWENGSDGKTFIREFMKDIYLVKPSLDDSFHIFGKMSPRRYINEYHKCGVENVVLTLGKDGVLVSDGEKVKKIH
TYAKNVVDTTGAGDAFWSGLYHGLLKGFDVFGAAKIGNAAAAFRLETEDKSVPIPSIEVLKKIMETRSIS
>Mature_310_residues
MKKILIIGELLIDLISEEYVDDLADAKSFKKYYAGSPGNLAINLKNLGIEPLLLASVGDDPFGRGYKKWLEEKGIKTTFI
NQSKLPTSFVIVSKSQDTPLFMPIRGADYKIEFPQEPEKLFEGVEFIHLTSWPLSRNPARKTVMKVLEIAKKRGTKVCFD
PNYREILWENGSDGKTFIREFMKDIYLVKPSLDDSFHIFGKMSPRRYINEYHKCGVENVVLTLGKDGVLVSDGEKVKKIH
TYAKNVVDTTGAGDAFWSGLYHGLLKGFDVFGAAKIGNAAAAFRLETEDKSVPIPSIEVLKKIMETRSIS

Specific function: Catalyzes the phosphorylation of 5-dehydro-2-deoxy-D- gluconate (2-deoxy-5-keto-D-gluconate or DKG) to 6-phospho-5- dehydro-2-deoxy-D-gluconate (DKGP) [H]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI87082281, Length=310, Percent_Identity=25.8064516129032, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI87081971, Length=314, Percent_Identity=22.6114649681529, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR022841 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.92 [H]

Molecular weight: Translated: 34824; Mature: 34824

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: PS00583 PFKB_KINASES_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKILIIGELLIDLISEEYVDDLADAKSFKKYYAGSPGNLAINLKNLGIEPLLLASVGDD
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCC
PFGRGYKKWLEEKGIKTTFINQSKLPTSFVIVSKSQDTPLFMPIRGADYKIEFPQEPEKL
CCCHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCCEEEEECCCCEEEECCCCHHHH
FEGVEFIHLTSWPLSRNPARKTVMKVLEIAKKRGTKVCFDPNYREILWENGSDGKTFIRE
HCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCHHHEEECCCCCHHHHHHH
FMKDIYLVKPSLDDSFHIFGKMSPRRYINEYHKCGVENVVLTLGKDGVLVSDGEKVKKIH
HHHHHEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCEEECCCHHHHHHH
TYAKNVVDTTGAGDAFWSGLYHGLLKGFDVFGAAKIGNAAAAFRLETEDKSVPIPSIEVL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCCCEEEEEEECCCCCCCCCHHHHH
KKIMETRSIS
HHHHHHCCCC
>Mature Secondary Structure
MKKILIIGELLIDLISEEYVDDLADAKSFKKYYAGSPGNLAINLKNLGIEPLLLASVGDD
CCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCC
PFGRGYKKWLEEKGIKTTFINQSKLPTSFVIVSKSQDTPLFMPIRGADYKIEFPQEPEKL
CCCHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCCEEEEECCCCEEEECCCCHHHH
FEGVEFIHLTSWPLSRNPARKTVMKVLEIAKKRGTKVCFDPNYREILWENGSDGKTFIRE
HCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEECCCHHHEEECCCCCHHHHHHH
FMKDIYLVKPSLDDSFHIFGKMSPRRYINEYHKCGVENVVLTLGKDGVLVSDGEKVKKIH
HHHHHEEECCCCCCCEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCEEECCCHHHHHHH
TYAKNVVDTTGAGDAFWSGLYHGLLKGFDVFGAAKIGNAAAAFRLETEDKSVPIPSIEVL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCHHHCCCCEEEEEEECCCCCCCCCHHHHH
KKIMETRSIS
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12552129 [H]