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The map label for this gene is ubiE [H]

Identifier: 239617357

GI number: 239617357

Start: 1022299

End: 1022901

Strand: Direct

Name: ubiE [H]

Synonym: Kole_0967

Alternate gene names: 239617357

Gene position: 1022299-1022901 (Clockwise)

Preceding gene: 239617347

Following gene: 239617359

Centisome position: 44.41

GC content: 37.65

Gene sequence:

>603_bases
ATGAGTGGGTTCACTTATGACGCAATAGCAAAGATATATGATCTGCTTCTTTTTCCTCTCGAAAAATTTGGGATTGAAAA
GCTAAGAAGAAGGTTTGTTCCCATGATTGAAGGTTATACTCTGGATCTTGCTGTTGGCACAGGGAACAACATAAAATATT
ATCCAGAGAGTTCAAAGGTCGTTCTCATAGATGCTTCCAGTAAAATGCTTAAAATTGCAGAGGAAAAAGCAAAAAAACAA
GCGAAAAACGTAAACTTAAAATTTGTCCATTCGCGCCTTGAAAATCTACCTTTTCCAGACAACTTTTTCGACACTATCCT
ATCTATAGATGTTTTTTGTTCAGTTCAAGACCAACAAAAAGCTCTTTTAGAGGTCGAAAGGGTTCTTAAACCCGGCGGAA
AGGCTATCTTTGTCGAGCACATGCTCACCGGGAAGCCTCTTAAAGACTTATGGTTATATTTGTTTAACGTAATAACTTAT
CCCACCGTAGGTTCATCAATGACTCGTAGAACTCTGCAAAACATAGAAAAAAGCGGTCTAGTTATTTTGAAGGTAGAGAA
CCTTCGGGGATCTTTCAAATATATACTCTGCACGAAAAACTGA

Upstream 100 bases:

>100_bases
TCGCTTATAATGTTCCATAATCCGCGCGTTTTTAGGAGGTCAATCAAAACTTTTATTGGGCAAATATTTGTTATATTATC
GTTATAAGGTTGGTGGGATA

Downstream 100 bases:

>100_bases
ACGGAAAAAGGAGCTGTATTTAAGACCTCTTCATTCCCACAAGTATCGTGGCAACGGTAACAACCTTTTCTTCTACCTTT
GCTTTGCCTTCAACAGTCAC

Product: Methyltransferase type 11

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 200; Mature: 199

Protein sequence:

>200_residues
MSGFTYDAIAKIYDLLLFPLEKFGIEKLRRRFVPMIEGYTLDLAVGTGNNIKYYPESSKVVLIDASSKMLKIAEEKAKKQ
AKNVNLKFVHSRLENLPFPDNFFDTILSIDVFCSVQDQQKALLEVERVLKPGGKAIFVEHMLTGKPLKDLWLYLFNVITY
PTVGSSMTRRTLQNIEKSGLVILKVENLRGSFKYILCTKN

Sequences:

>Translated_200_residues
MSGFTYDAIAKIYDLLLFPLEKFGIEKLRRRFVPMIEGYTLDLAVGTGNNIKYYPESSKVVLIDASSKMLKIAEEKAKKQ
AKNVNLKFVHSRLENLPFPDNFFDTILSIDVFCSVQDQQKALLEVERVLKPGGKAIFVEHMLTGKPLKDLWLYLFNVITY
PTVGSSMTRRTLQNIEKSGLVILKVENLRGSFKYILCTKN
>Mature_199_residues
SGFTYDAIAKIYDLLLFPLEKFGIEKLRRRFVPMIEGYTLDLAVGTGNNIKYYPESSKVVLIDASSKMLKIAEEKAKKQA
KNVNLKFVHSRLENLPFPDNFFDTILSIDVFCSVQDQQKALLEVERVLKPGGKAIFVEHMLTGKPLKDLWLYLFNVITYP
TVGSSMTRRTLQNIEKSGLVILKVENLRGSFKYILCTKN

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Homo sapiens, GI164663805, Length=197, Percent_Identity=28.4263959390863, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI89145417, Length=165, Percent_Identity=29.6969696969697, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI48994983, Length=179, Percent_Identity=35.7541899441341, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1786404, Length=96, Percent_Identity=39.5833333333333, Blast_Score=70, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.-

Molecular weight: Translated: 22834; Mature: 22703

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGFTYDAIAKIYDLLLFPLEKFGIEKLRRRFVPMIEGYTLDLAVGTGNNIKYYPESSKV
CCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCHHHCCEEEEEEEECCCCEEECCCCCEE
VLIDASSKMLKIAEEKAKKQAKNVNLKFVHSRLENLPFPDNFFDTILSIDVFCSVQDQQK
EEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCHHHH
ALLEVERVLKPGGKAIFVEHMLTGKPLKDLWLYLFNVITYPTVGSSMTRRTLQNIEKSGL
HHHHHHHHHCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCE
VILKVENLRGSFKYILCTKN
EEEEEECCCCCEEEEEEECC
>Mature Secondary Structure 
SGFTYDAIAKIYDLLLFPLEKFGIEKLRRRFVPMIEGYTLDLAVGTGNNIKYYPESSKV
CCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCHHHCCEEEEEEEECCCCEEECCCCCEE
VLIDASSKMLKIAEEKAKKQAKNVNLKFVHSRLENLPFPDNFFDTILSIDVFCSVQDQQK
EEEECCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHEECCCHHHH
ALLEVERVLKPGGKAIFVEHMLTGKPLKDLWLYLFNVITYPTVGSSMTRRTLQNIEKSGL
HHHHHHHHHCCCCCEEEEEHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCE
VILKVENLRGSFKYILCTKN
EEEEEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA