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The map label for this gene is fabH [H]

Identifier: 239617359

GI number: 239617359

Start: 1023525

End: 1024505

Strand: Direct

Name: fabH [H]

Synonym: Kole_0969

Alternate gene names: 239617359

Gene position: 1023525-1024505 (Clockwise)

Preceding gene: 239617357

Following gene: 239617360

Centisome position: 44.46

GC content: 41.79

Gene sequence:

>981_bases
ATGTCAATAAATGTTATTGGAACAGGGGCGTATTTACCGCCCAAAGTTGTTACGAACCAGGAATTAGCCACAATGCTAGA
CATTTCTCCAGAGTGGATTGAACGCCGAACGGGCATCAAAGAAAGACGATTTGCAACTGAAGATACTCTGCTATCTATGG
CTGTAAAAGCATCTCTGAAAGCTCTCGAGAATTTTGATAAAAATGTTGATTTTATTGTTGCTCATTCATCTTCTGTGGAG
GAAAGCTTCCCATCGCTCTCTTCCTCAATTGCCAAAGAATTGGGTATAAAACCCAAGCTTGCTTTCGATCTGGTTTCAGG
ATGCACTGGTTTTCTTCAAGCACTTTTAACAGCATCTTCTGCAATGGAACAATTCAATCTGAACACAGCTTTAGTTGTCG
CTTCAGAACATCTAAGCAAACATCTCGATTTTTCCGATAGAGATACCGCTATCATCTTTGGTGATGGTGCCGGGGCCCTT
CTCTTGGAAAAATCCACTGGTAACGACTTTATTATCGGCTACGATCTTGGAACCATGGTGGAAAGGAAAGACAGTCTTTC
ATTGAAAGCTGGAACAACAAGCAAGATCAAAATGCGAGGTACCGAAGTATTTCGTTTTGCCGTTCGTGCACTAACACGTT
CCATAGAGAACTCACTCAAAAAGGCCGGAATCGGTCCGGAAGAGCTGGATTTCATCATACCACACCAGTCAAATTCAAGA
ATTTTGGAATCCGCAAACAAAATTCTACAAATTCCTGAAGAGAAGATCATTTCACATCTAACGTATTACGGTAATACCGG
GTCGGCTTCTATTCCGATAGCAATAGATCTTGCTACAAGAGAAGGAAAATTACAGCAGGGTCAAAAAATACTCTTCACCA
GTTACGGTGCTGGTTTATCATGGACAAGTTTGCTGGTTGAGTGGAGAACCGGGAAGGAGGAATGGAGTTGCATCTTAGAA
ACAGTATTTCAAGGTTACTAG

Upstream 100 bases:

>100_bases
GAATATCGAACGTTTTTTTGCTTAAAAAGCATGGCATATTGTTGCTATGAGTTAAGAGCACTCACAAAAACGAGTTGCAG
AGATTATGGAGGGGATCAAA

Downstream 100 bases:

>100_bases
GGATAAAATATCCAATTCTACAGGGAGGAATGGCCTGGGTTTCTACGGCGGAGCTGGTCTCCGCTGTCTCGAATGCTGGT
GGTCTTGGAATAATAGCGGC

Product: 3-oxoacyl-(acyl-carrier-protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSINVIGTGAYLPPKVVTNQELATMLDISPEWIERRTGIKERRFATEDTLLSMAVKASLKALENFDKNVDFIVAHSSSVE
ESFPSLSSSIAKELGIKPKLAFDLVSGCTGFLQALLTASSAMEQFNLNTALVVASEHLSKHLDFSDRDTAIIFGDGAGAL
LLEKSTGNDFIIGYDLGTMVERKDSLSLKAGTTSKIKMRGTEVFRFAVRALTRSIENSLKKAGIGPEELDFIIPHQSNSR
ILESANKILQIPEEKIISHLTYYGNTGSASIPIAIDLATREGKLQQGQKILFTSYGAGLSWTSLLVEWRTGKEEWSCILE
TVFQGY

Sequences:

>Translated_326_residues
MSINVIGTGAYLPPKVVTNQELATMLDISPEWIERRTGIKERRFATEDTLLSMAVKASLKALENFDKNVDFIVAHSSSVE
ESFPSLSSSIAKELGIKPKLAFDLVSGCTGFLQALLTASSAMEQFNLNTALVVASEHLSKHLDFSDRDTAIIFGDGAGAL
LLEKSTGNDFIIGYDLGTMVERKDSLSLKAGTTSKIKMRGTEVFRFAVRALTRSIENSLKKAGIGPEELDFIIPHQSNSR
ILESANKILQIPEEKIISHLTYYGNTGSASIPIAIDLATREGKLQQGQKILFTSYGAGLSWTSLLVEWRTGKEEWSCILE
TVFQGY
>Mature_325_residues
SINVIGTGAYLPPKVVTNQELATMLDISPEWIERRTGIKERRFATEDTLLSMAVKASLKALENFDKNVDFIVAHSSSVEE
SFPSLSSSIAKELGIKPKLAFDLVSGCTGFLQALLTASSAMEQFNLNTALVVASEHLSKHLDFSDRDTAIIFGDGAGALL
LEKSTGNDFIIGYDLGTMVERKDSLSLKAGTTSKIKMRGTEVFRFAVRALTRSIENSLKKAGIGPEELDFIIPHQSNSRI
LESANKILQIPEEKIISHLTYYGNTGSASIPIAIDLATREGKLQQGQKILFTSYGAGLSWTSLLVEWRTGKEEWSCILET
VFQGY

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=317, Percent_Identity=35.9621451104101, Blast_Score=204, Evalue=9e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 35705; Mature: 35574

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSINVIGTGAYLPPKVVTNQELATMLDISPEWIERRTGIKERRFATEDTLLSMAVKASLK
CEEEEEECCCCCCCCCCCCHHHHHHHCCCHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHH
ALENFDKNVDFIVAHSSSVEESFPSLSSSIAKELGIKPKLAFDLVSGCTGFLQALLTASS
HHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AMEQFNLNTALVVASEHLSKHLDFSDRDTAIIFGDGAGALLLEKSTGNDFIIGYDLGTMV
HHHHHCCCEEEEEEHHHHHHHCCCCCCCCEEEEECCCCEEEEEECCCCCEEEEECHHHHH
ERKDSLSLKAGTTSKIKMRGTEVFRFAVRALTRSIENSLKKAGIGPEELDFIIPHQSNSR
HCCCCCEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCEEEECCCCCCH
ILESANKILQIPEEKIISHLTYYGNTGSASIPIAIDLATREGKLQQGQKILFTSYGAGLS
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHCCCEEEEEECCCCCC
WTSLLVEWRTGKEEWSCILETVFQGY
HHHHHEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SINVIGTGAYLPPKVVTNQELATMLDISPEWIERRTGIKERRFATEDTLLSMAVKASLK
EEEEEECCCCCCCCCCCCHHHHHHHCCCHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHH
ALENFDKNVDFIVAHSSSVEESFPSLSSSIAKELGIKPKLAFDLVSGCTGFLQALLTASS
HHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
AMEQFNLNTALVVASEHLSKHLDFSDRDTAIIFGDGAGALLLEKSTGNDFIIGYDLGTMV
HHHHHCCCEEEEEEHHHHHHHCCCCCCCCEEEEECCCCEEEEEECCCCCEEEEECHHHHH
ERKDSLSLKAGTTSKIKMRGTEVFRFAVRALTRSIENSLKKAGIGPEELDFIIPHQSNSR
HCCCCCEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCEEEECCCCCCH
ILESANKILQIPEEKIISHLTYYGNTGSASIPIAIDLATREGKLQQGQKILFTSYGAGLS
HHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHCCCEEEEEECCCCCC
WTSLLVEWRTGKEEWSCILETVFQGY
HHHHHEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]