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The map label for this gene is pcp [H]

Identifier: 239617212

GI number: 239617212

Start: 869493

End: 870089

Strand: Direct

Name: pcp [H]

Synonym: Kole_0819

Alternate gene names: 239617212

Gene position: 869493-870089 (Clockwise)

Preceding gene: 239617211

Following gene: 239617213

Centisome position: 37.77

GC content: 42.55

Gene sequence:

>597_bases
GTGATACTGCTCAGTCATTTCGATGCTTTCGGTGAAGATAGAGAAAACTCCACAGAAATACTGTTAAGTACCTTTAAAAC
CCGGAACAATGTACAAGTCGTCAAACTCCCTACTGTTTTCAGAAAAAGTGGTGAGATACTTATAAAAGAAATCGAAAAGA
CTAAACCTTCTGCAGTGGTCATGCTGGGACAAGCCGGTGGTAGAACGGCTGTAACCCCGGAAAAAGTGGCTATAAACATT
ATGGATGCAAGGATAAAAGATAATGAAGGAAACAAACCCTGTGATGAGCCTGTGGTTGAAGGTGGACCAACCGCTTACTT
TTCCACTCTTCCTGTAAGAGAAATAACTGAAAAACTCAGGAAAAACGGAATTCCCGCTGCTATTTCCTACACAGCGGGGA
CTTTTGTATGCAACAGCCTTTTCTACCAGATTATGCATTACCTATCTGAAAATGATTTAAGTATAAGAGCTGGATTTATT
CATTTTCCGTATCTTCATCGGCAGGTAGCTGAAAGACCGCAAATACCTTCCATGGGGCTTATCGAAATGCAGCGGGCCAT
GGAGATAATCCTGGAGGTCGTGGAGGCCAAGCTATGA

Upstream 100 bases:

>100_bases
AATTTAATCATGGTTTCATGGTGCTTTTGAATTTCATCACTCTGGTGGAATACTATGACTCTAAGTCTTATTAAAGTTGT
AATTTCGTGGAGGTGATAAG

Downstream 100 bases:

>100_bases
AGATAGCAATAGCGGAAATTGCACCTTTCTGGGAATCCAAGGATGAAAACAAAAAAATGGTGAGTGAGCTCTTCAACCAA
GCCCGTGCTGGAGAAGTTGA

Product: pyrrolidone-carboxylate peptidase

Products: NA

Alternate protein names: 5-oxoprolyl-peptidase; Pyroglutamyl-peptidase I; PGP-I; Pyrase [H]

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MILLSHFDAFGEDRENSTEILLSTFKTRNNVQVVKLPTVFRKSGEILIKEIEKTKPSAVVMLGQAGGRTAVTPEKVAINI
MDARIKDNEGNKPCDEPVVEGGPTAYFSTLPVREITEKLRKNGIPAAISYTAGTFVCNSLFYQIMHYLSENDLSIRAGFI
HFPYLHRQVAERPQIPSMGLIEMQRAMEIILEVVEAKL

Sequences:

>Translated_198_residues
MILLSHFDAFGEDRENSTEILLSTFKTRNNVQVVKLPTVFRKSGEILIKEIEKTKPSAVVMLGQAGGRTAVTPEKVAINI
MDARIKDNEGNKPCDEPVVEGGPTAYFSTLPVREITEKLRKNGIPAAISYTAGTFVCNSLFYQIMHYLSENDLSIRAGFI
HFPYLHRQVAERPQIPSMGLIEMQRAMEIILEVVEAKL
>Mature_198_residues
MILLSHFDAFGEDRENSTEILLSTFKTRNNVQVVKLPTVFRKSGEILIKEIEKTKPSAVVMLGQAGGRTAVTPEKVAINI
MDARIKDNEGNKPCDEPVVEGGPTAYFSTLPVREITEKLRKNGIPAAISYTAGTFVCNSLFYQIMHYLSENDLSIRAGFI
HFPYLHRQVAERPQIPSMGLIEMQRAMEIILEVVEAKL

Specific function: Removes 5-oxoproline from various penultimate amino acid residues except L-proline [H]

COG id: COG2039

COG function: function code O; Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C15 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000816
- InterPro:   IPR016125 [H]

Pfam domain/function: PF01470 Peptidase_C15 [H]

EC number: =3.4.19.3 [H]

Molecular weight: Translated: 22152; Mature: 22152

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS01333 PYRASE_GLU ; PS01334 PYRASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILLSHFDAFGEDRENSTEILLSTFKTRNNVQVVKLPTVFRKSGEILIKEIEKTKPSAVV
CEEECCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECHHHHCCCHHHHHHHHCCCCCEEE
MLGQAGGRTAVTPEKVAINIMDARIKDNEGNKPCDEPVVEGGPTAYFSTLPVREITEKLR
EEECCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHH
KNGIPAAISYTAGTFVCNSLFYQIMHYLSENDLSIRAGFIHFPYLHRQVAERPQIPSMGL
HCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHCCCCCCCCH
IEMQRAMEIILEVVEAKL
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MILLSHFDAFGEDRENSTEILLSTFKTRNNVQVVKLPTVFRKSGEILIKEIEKTKPSAVV
CEEECCCCCCCCCCCCCHHHHHHHHCCCCCEEEEEECHHHHCCCHHHHHHHHCCCCCEEE
MLGQAGGRTAVTPEKVAINIMDARIKDNEGNKPCDEPVVEGGPTAYFSTLPVREITEKLR
EEECCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHH
KNGIPAAISYTAGTFVCNSLFYQIMHYLSENDLSIRAGFIHFPYLHRQVAERPQIPSMGL
HCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHHHHHHCCCCCCCCH
IEMQRAMEIILEVVEAKL
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA