Click here to switch to the map view.

The map label for this gene is guaAA [H]

Identifier: 239617211

GI number: 239617211

Start: 868801

End: 869466

Strand: Direct

Name: guaAA [H]

Synonym: Kole_0818

Alternate gene names: 239617211

Gene position: 868801-869466 (Clockwise)

Preceding gene: 239617210

Following gene: 239617212

Centisome position: 37.74

GC content: 38.59

Gene sequence:

>666_bases
TTGAAAGTATTTCTGGTAGTTTCCCTTCTATTACTTTCAATAAGCATATTTGCTTTGAACAAACCTATAGCTCTACTTTT
AAACGACGGAGACTATCTAAATACTACCTCTCTCATAGAAAAAGCACTTAAAGATCTCAAAGTTGATTACAAGCTTTACA
GAACTTTTCTCGGAGAATTCCCGGAAAAAGGAAGTTATTCGGGCATAATTTTGAGCGGTGGAAGTGATATGAGCGCTTTT
TTTAATAATGATGGAAGCGCGAAAGAAACGGTAAAACTAATAACGGAAAGCAATGTCCCTGTTCTGGGGATATGTATGGG
ACACCAGCTAATTGGTAAGATCTACGGAGCATCTCTAATCTATCTCGAAGAACGCGGCTGGATTGAGGTAAAAGAACTGA
AAGATAACGTTCTTTTCACAGGCTTACCGGAAGTCTTCAATGTCTGGGAAAATCACATGTATACTCTCAATAAAGTTCCC
GAAGATTTCGAACTCCTCGCTATCGGTGAATCCGGTTCCATTCAAGTGATAAAACACCGTGAAAAGCCAATTTACGGCGT
TCAATTTCACCCGGAAAAGGGCGACAACAAGAAATTTAATCATGGTTTCATGGTGCTTTTGAATTTCATCACTCTGGTGG
AATACTATGACTCTAAGTCTTATTAA

Upstream 100 bases:

>100_bases
TTTTAGAAAAGGAAAATACTACGACGAAATAATTATGGGGATTTTAAGGCGAGAATTTCTAAGAACTATCTCTGATTAAC
AAATAGGAGGTGTCGCCCAA

Downstream 100 bases:

>100_bases
AGTTGTAATTTCGTGGAGGTGATAAGGTGATACTGCTCAGTCATTTCGATGCTTTCGGTGAAGATAGAGAAAACTCCACA
GAAATACTGTTAAGTACCTT

Product: glutamine amidotransferase class-I

Products: NA

Alternate protein names: Glutamine amidotransferase [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MKVFLVVSLLLLSISIFALNKPIALLLNDGDYLNTTSLIEKALKDLKVDYKLYRTFLGEFPEKGSYSGIILSGGSDMSAF
FNNDGSAKETVKLITESNVPVLGICMGHQLIGKIYGASLIYLEERGWIEVKELKDNVLFTGLPEVFNVWENHMYTLNKVP
EDFELLAIGESGSIQVIKHREKPIYGVQFHPEKGDNKKFNHGFMVLLNFITLVEYYDSKSY

Sequences:

>Translated_221_residues
MKVFLVVSLLLLSISIFALNKPIALLLNDGDYLNTTSLIEKALKDLKVDYKLYRTFLGEFPEKGSYSGIILSGGSDMSAF
FNNDGSAKETVKLITESNVPVLGICMGHQLIGKIYGASLIYLEERGWIEVKELKDNVLFTGLPEVFNVWENHMYTLNKVP
EDFELLAIGESGSIQVIKHREKPIYGVQFHPEKGDNKKFNHGFMVLLNFITLVEYYDSKSY
>Mature_221_residues
MKVFLVVSLLLLSISIFALNKPIALLLNDGDYLNTTSLIEKALKDLKVDYKLYRTFLGEFPEKGSYSGIILSGGSDMSAF
FNNDGSAKETVKLITESNVPVLGICMGHQLIGKIYGASLIYLEERGWIEVKELKDNVLFTGLPEVFNVWENHMYTLNKVP
EDFELLAIGESGSIQVIKHREKPIYGVQFHPEKGDNKKFNHGFMVLLNFITLVEYYDSKSY

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG0518

COG function: function code F; GMP synthase - Glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788854, Length=186, Percent_Identity=28.494623655914, Blast_Score=76, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6323873, Length=128, Percent_Identity=35.9375, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR004739 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 24972; Mature: 24972

Theoretical pI: Translated: 5.66; Mature: 5.66

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVFLVVSLLLLSISIFALNKPIALLLNDGDYLNTTSLIEKALKDLKVDYKLYRTFLGEF
CHHHHHHHHHHHHHHHHEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PEKGSYSGIILSGGSDMSAFFNNDGSAKETVKLITESNVPVLGICMGHQLIGKIYGASLI
CCCCCCCEEEEECCCCCCCEECCCCCHHHHEEEEECCCCCEEEEEHHHHHHHHHHCCEEE
YLEERGWIEVKELKDNVLFTGLPEVFNVWENHMYTLNKVPEDFELLAIGESGSIQVIKHR
EEECCCCEEEEECCCCEEEECCHHHHHHHHHCEEEECCCCCCEEEEEECCCCCEEEEEEC
EKPIYGVQFHPEKGDNKKFNHGFMVLLNFITLVEYYDSKSY
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKVFLVVSLLLLSISIFALNKPIALLLNDGDYLNTTSLIEKALKDLKVDYKLYRTFLGEF
CHHHHHHHHHHHHHHHHEECCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
PEKGSYSGIILSGGSDMSAFFNNDGSAKETVKLITESNVPVLGICMGHQLIGKIYGASLI
CCCCCCCEEEEECCCCCCCEECCCCCHHHHEEEEECCCCCEEEEEHHHHHHHHHHCCEEE
YLEERGWIEVKELKDNVLFTGLPEVFNVWENHMYTLNKVPEDFELLAIGESGSIQVIKHR
EEECCCCEEEEECCCCEEEECCHHHHHHHHHCEEEECCCCCCEEEEEECCCCCEEEEEEC
EKPIYGVQFHPEKGDNKKFNHGFMVLLNFITLVEYYDSKSY
CCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA