| Definition | Kosmotoga olearia TBF 19.5.1, complete genome. |
|---|---|
| Accession | NC_012785 |
| Length | 2,302,126 |
Click here to switch to the map view.
The map label for this gene is ucpA [C]
Identifier: 239617024
GI number: 239617024
Start: 669560
End: 670834
Strand: Direct
Name: ucpA [C]
Synonym: Kole_0624
Alternate gene names: 239617024
Gene position: 669560-670834 (Clockwise)
Preceding gene: 239617023
Following gene: 239617025
Centisome position: 29.08
GC content: 47.06
Gene sequence:
>1275_bases ATGCTTATCGAGAAAATGGGGTTATCCCGCACTGCCCTTGCAGGAAAAGTGGCAGTTATTACAGGTGCAGGCCAGGGAAT CGGTAAAGAATTAGCAAGAGCACTGGCATGGCTTGGTGCCAAGGTCATCATTGCCGAAATCAGGGATACAGGTGCTGAAG TTGAAACCTTAATACGTTCAGAAGGAGGCACGGCCATGTTTGTCCAAACCGACGTTAGTGACGAAAAAAGTATTCAGGCA TTAGCCAAAAAGGCTTTTAATACCTTTGGCAAGGTAGATATTCTGGTGAACAACGCCATTATCTACCGCCCCGGTACCAT CCTGGAGCTCCCAATAGAGGCCTGGGATCAGGTTTATGCCGTAAATCTGCGTGGCGCGGTGCTAGGCATTAAAGCGTTTT TGCCGGGAATGCTCGAGCGCAAGGAAGGCGTTATAGTAACAATTACATCGAGCGAAGGCATGCCGTATATGGCCTCCTAT TTTGCATCAAAGGCTGCGTTACAGTCTCTTGGACTATCCCTTGCAGGTGAATTGAGCGAAGAATCAGGTGTATCAGCCTT TGTTTTTGCACCCGGGATGGTGGATACACCCGGAGGAAATCAGGCATTCCAGGCGCTGGCACCAAAATACGGTATGTCTT ACCAGGAATTTATAAATATGAGTCCCAATCCCGGCTATAATGGTCTAATGCCGGCTGAAGACTGCGCCGCAGGCTTTGCA TACGCCATTGTCCATGCCCGGGATTATCATGGTCAAATCGCTGATCCCTTCCAGATTCTCGCTAAAACAGGCCTTCTACA ATTTTCATCGCAGCCAAAAACCGACAACACTGTCCCAGCCGAATCCTCCTTGGAAAAACCCGCAGGAAAGAAATCGGCGA TTGAGCTTGCCAGAGAAGTAAAGAAAATCCTGGAAGCGGTTAATAAAGAAGCCAACGAACTCGATCTGTTCAGGAAAATG TGGGTTACCCGTGCATTCCGACAGAGAACTGGAATGAGCATCAAAGACTGGCTGGAAACAGTTACAGAATTGGTTGCTGA ACTCGAGGCTGCAGAAACCGGAGACACCACAAAAATCGAAAACATTCGCGGCAAGTTACCCTGGTTAAAAAGTAACCTTG AGAGGCTTGCCGATTATTTCAAGAAGAATATGAAAGACGCAGAAGGATATTTCAAAGATCCAAAAGCTCTAGCTAAAGCT CTGGAGGTTTTAACCTACCGGGTAAATACTGTGCGATCGTTAATTTCGGCATTAGAGCAAAAAGTTAAACCGTAG
Upstream 100 bases:
>100_bases CTTCTCGGCTCTCGGTTCTCGGATTCTCGAATCTCGATGCATATCTGTTATGATAAAATTCCTACCCAAAACATAAATTA TTAAACCAGAGGGGATTGGG
Downstream 100 bases:
>100_bases ACAAAGACGAATCTTTAATCTTTAGGATAACTTTTTTCGCTTCACAAAGCATCTATGCTTTCCAAACTCGCCTTTGTTCT TCGGGATCAGGCTTCTTCCA
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 424; Mature: 424
Protein sequence:
>424_residues MLIEKMGLSRTALAGKVAVITGAGQGIGKELARALAWLGAKVIIAEIRDTGAEVETLIRSEGGTAMFVQTDVSDEKSIQA LAKKAFNTFGKVDILVNNAIIYRPGTILELPIEAWDQVYAVNLRGAVLGIKAFLPGMLERKEGVIVTITSSEGMPYMASY FASKAALQSLGLSLAGELSEESGVSAFVFAPGMVDTPGGNQAFQALAPKYGMSYQEFINMSPNPGYNGLMPAEDCAAGFA YAIVHARDYHGQIADPFQILAKTGLLQFSSQPKTDNTVPAESSLEKPAGKKSAIELAREVKKILEAVNKEANELDLFRKM WVTRAFRQRTGMSIKDWLETVTELVAELEAAETGDTTKIENIRGKLPWLKSNLERLADYFKKNMKDAEGYFKDPKALAKA LEVLTYRVNTVRSLISALEQKVKP
Sequences:
>Translated_424_residues MLIEKMGLSRTALAGKVAVITGAGQGIGKELARALAWLGAKVIIAEIRDTGAEVETLIRSEGGTAMFVQTDVSDEKSIQA LAKKAFNTFGKVDILVNNAIIYRPGTILELPIEAWDQVYAVNLRGAVLGIKAFLPGMLERKEGVIVTITSSEGMPYMASY FASKAALQSLGLSLAGELSEESGVSAFVFAPGMVDTPGGNQAFQALAPKYGMSYQEFINMSPNPGYNGLMPAEDCAAGFA YAIVHARDYHGQIADPFQILAKTGLLQFSSQPKTDNTVPAESSLEKPAGKKSAIELAREVKKILEAVNKEANELDLFRKM WVTRAFRQRTGMSIKDWLETVTELVAELEAAETGDTTKIENIRGKLPWLKSNLERLADYFKKNMKDAEGYFKDPKALAKA LEVLTYRVNTVRSLISALEQKVKP >Mature_424_residues MLIEKMGLSRTALAGKVAVITGAGQGIGKELARALAWLGAKVIIAEIRDTGAEVETLIRSEGGTAMFVQTDVSDEKSIQA LAKKAFNTFGKVDILVNNAIIYRPGTILELPIEAWDQVYAVNLRGAVLGIKAFLPGMLERKEGVIVTITSSEGMPYMASY FASKAALQSLGLSLAGELSEESGVSAFVFAPGMVDTPGGNQAFQALAPKYGMSYQEFINMSPNPGYNGLMPAEDCAAGFA YAIVHARDYHGQIADPFQILAKTGLLQFSSQPKTDNTVPAESSLEKPAGKKSAIELAREVKKILEAVNKEANELDLFRKM WVTRAFRQRTGMSIKDWLETVTELVAELEAAETGDTTKIENIRGKLPWLKSNLERLADYFKKNMKDAEGYFKDPKALAKA LEVLTYRVNTVRSLISALEQKVKP
Specific function: Unknown
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI20149619, Length=212, Percent_Identity=37.2641509433962, Blast_Score=107, Evalue=2e-23, Organism=Homo sapiens, GI210032110, Length=194, Percent_Identity=32.9896907216495, Blast_Score=91, Evalue=1e-18, Organism=Homo sapiens, GI40807363, Length=218, Percent_Identity=32.1100917431193, Blast_Score=89, Evalue=8e-18, Organism=Homo sapiens, GI142976729, Length=195, Percent_Identity=32.8205128205128, Blast_Score=89, Evalue=1e-17, Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=32.4742268041237, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI40254986, Length=269, Percent_Identity=30.4832713754647, Blast_Score=82, Evalue=9e-16, Organism=Homo sapiens, GI157739938, Length=183, Percent_Identity=31.1475409836066, Blast_Score=82, Evalue=1e-15, Organism=Homo sapiens, GI109715829, Length=255, Percent_Identity=28.2352941176471, Blast_Score=81, Evalue=2e-15, Organism=Homo sapiens, GI209862901, Length=204, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=2e-15, Organism=Homo sapiens, GI19923983, Length=204, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=2e-15, Organism=Homo sapiens, GI310128830, Length=212, Percent_Identity=29.7169811320755, Blast_Score=81, Evalue=2e-15, Organism=Homo sapiens, GI310115468, Length=212, Percent_Identity=29.7169811320755, Blast_Score=81, Evalue=2e-15, Organism=Homo sapiens, GI32483357, Length=194, Percent_Identity=32.4742268041237, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI66933014, Length=200, Percent_Identity=35, Blast_Score=80, Evalue=4e-15, Organism=Homo sapiens, GI25282469, Length=216, Percent_Identity=30.0925925925926, Blast_Score=80, Evalue=4e-15, Organism=Homo sapiens, GI4504505, Length=217, Percent_Identity=30.8755760368664, Blast_Score=80, Evalue=5e-15, Organism=Homo sapiens, GI31542939, Length=193, Percent_Identity=31.6062176165803, Blast_Score=78, Evalue=2e-14, Organism=Homo sapiens, GI7657478, Length=177, Percent_Identity=38.9830508474576, Blast_Score=78, Evalue=2e-14, Organism=Homo sapiens, GI19923817, Length=217, Percent_Identity=28.110599078341, Blast_Score=75, Evalue=1e-13, Organism=Homo sapiens, GI224922801, Length=162, Percent_Identity=30.8641975308642, Blast_Score=71, Evalue=2e-12, Organism=Homo sapiens, GI7705925, Length=170, Percent_Identity=32.3529411764706, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI5031737, Length=200, Percent_Identity=30.5, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI4758504, Length=208, Percent_Identity=29.3269230769231, Blast_Score=70, Evalue=4e-12, Organism=Homo sapiens, GI126723191, Length=177, Percent_Identity=31.638418079096, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=31.2169312169312, Blast_Score=69, Evalue=9e-12, Organism=Homo sapiens, GI223718074, Length=173, Percent_Identity=35.8381502890173, Blast_Score=68, Evalue=1e-11, Organism=Homo sapiens, GI4503817, Length=196, Percent_Identity=29.0816326530612, Blast_Score=66, Evalue=8e-11, Organism=Escherichia coli, GI87082100, Length=192, Percent_Identity=38.5416666666667, Blast_Score=102, Evalue=4e-23, Organism=Escherichia coli, GI1787335, Length=185, Percent_Identity=35.6756756756757, Blast_Score=99, Evalue=4e-22, Organism=Escherichia coli, GI1790717, Length=190, Percent_Identity=35.7894736842105, Blast_Score=88, Evalue=1e-18, Organism=Escherichia coli, GI1787905, Length=139, Percent_Identity=39.568345323741, Blast_Score=84, Evalue=1e-17, Organism=Escherichia coli, GI87082160, Length=188, Percent_Identity=30.8510638297872, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI1786812, Length=187, Percent_Identity=35.2941176470588, Blast_Score=77, Evalue=2e-15, Organism=Escherichia coli, GI1787820, Length=216, Percent_Identity=30.0925925925926, Blast_Score=74, Evalue=3e-14, Organism=Escherichia coli, GI1789057, Length=251, Percent_Identity=29.0836653386454, Blast_Score=73, Evalue=4e-14, Organism=Escherichia coli, GI1789208, Length=200, Percent_Identity=29, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1788459, Length=188, Percent_Identity=30.3191489361702, Blast_Score=69, Evalue=8e-13, Organism=Escherichia coli, GI1789378, Length=198, Percent_Identity=28.2828282828283, Blast_Score=64, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=34.8717948717949, Blast_Score=100, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17567345, Length=200, Percent_Identity=31.5, Blast_Score=96, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17508895, Length=218, Percent_Identity=32.5688073394495, Blast_Score=92, Evalue=7e-19, Organism=Caenorhabditis elegans, GI193203115, Length=209, Percent_Identity=34.4497607655502, Blast_Score=90, Evalue=3e-18, Organism=Caenorhabditis elegans, GI193203117, Length=204, Percent_Identity=34.3137254901961, Blast_Score=89, Evalue=5e-18, Organism=Caenorhabditis elegans, GI17568967, Length=200, Percent_Identity=34, Blast_Score=88, Evalue=1e-17, Organism=Caenorhabditis elegans, GI25147288, Length=190, Percent_Identity=30, Blast_Score=77, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71994600, Length=188, Percent_Identity=30.8510638297872, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI71982365, Length=178, Percent_Identity=29.2134831460674, Blast_Score=74, Evalue=2e-13, Organism=Caenorhabditis elegans, GI71994604, Length=188, Percent_Identity=29.7872340425532, Blast_Score=71, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17558628, Length=149, Percent_Identity=32.8859060402685, Blast_Score=68, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17562910, Length=197, Percent_Identity=33.502538071066, Blast_Score=68, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17536025, Length=198, Percent_Identity=32.8282828282828, Blast_Score=67, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17538486, Length=229, Percent_Identity=31.0043668122271, Blast_Score=66, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17560332, Length=198, Percent_Identity=31.8181818181818, Blast_Score=65, Evalue=5e-11, Organism=Saccharomyces cerevisiae, GI6322226, Length=186, Percent_Identity=31.1827956989247, Blast_Score=84, Evalue=3e-17, Organism=Saccharomyces cerevisiae, GI6322227, Length=210, Percent_Identity=30, Blast_Score=72, Evalue=2e-13, Organism=Drosophila melanogaster, GI24639444, Length=198, Percent_Identity=37.3737373737374, Blast_Score=94, Evalue=1e-19, Organism=Drosophila melanogaster, GI23397609, Length=215, Percent_Identity=35.8139534883721, Blast_Score=94, Evalue=2e-19, Organism=Drosophila melanogaster, GI21355631, Length=178, Percent_Identity=32.5842696629214, Blast_Score=90, Evalue=2e-18, Organism=Drosophila melanogaster, GI24640492, Length=190, Percent_Identity=31.5789473684211, Blast_Score=89, Evalue=5e-18, Organism=Drosophila melanogaster, GI281364892, Length=167, Percent_Identity=32.9341317365269, Blast_Score=87, Evalue=3e-17, Organism=Drosophila melanogaster, GI21358495, Length=210, Percent_Identity=29.5238095238095, Blast_Score=86, Evalue=4e-17, Organism=Drosophila melanogaster, GI21355319, Length=194, Percent_Identity=32.9896907216495, Blast_Score=80, Evalue=3e-15, Organism=Drosophila melanogaster, GI18859837, Length=177, Percent_Identity=35.5932203389831, Blast_Score=77, Evalue=2e-14, Organism=Drosophila melanogaster, GI21357041, Length=186, Percent_Identity=30.1075268817204, Blast_Score=74, Evalue=1e-13, Organism=Drosophila melanogaster, GI28571526, Length=189, Percent_Identity=29.1005291005291, Blast_Score=74, Evalue=2e-13, Organism=Drosophila melanogaster, GI24644339, Length=220, Percent_Identity=29.5454545454545, Blast_Score=73, Evalue=4e-13, Organism=Drosophila melanogaster, GI21357673, Length=193, Percent_Identity=29.0155440414508, Blast_Score=73, Evalue=4e-13, Organism=Drosophila melanogaster, GI17737361, Length=197, Percent_Identity=31.4720812182741, Blast_Score=71, Evalue=1e-12, Organism=Drosophila melanogaster, GI24641232, Length=245, Percent_Identity=29.3877551020408, Blast_Score=71, Evalue=1e-12, Organism=Drosophila melanogaster, GI24580925, Length=299, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=2e-12, Organism=Drosophila melanogaster, GI24649181, Length=176, Percent_Identity=30.6818181818182, Blast_Score=68, Evalue=9e-12, Organism=Drosophila melanogaster, GI116007236, Length=194, Percent_Identity=30.4123711340206, Blast_Score=66, Evalue=4e-11, Organism=Drosophila melanogaster, GI24665243, Length=197, Percent_Identity=28.9340101522843, Blast_Score=66, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 46112; Mature: 46112
Theoretical pI: Translated: 7.49; Mature: 7.49
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.2 %Cys (Translated Protein) 3.1 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 0.2 %Cys (Mature Protein) 3.1 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MLIEKMGLSRTALAGKVAVITGAGQGIGKELARALAWLGAKVIIAEIRDTGAEVETLIRS CCCCCCCCCHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEEHHHHCCHHHHHHHHC EGGTAMFVQTDVSDEKSIQALAKKAFNTFGKVDILVNNAIIYRPGTILELPIEAWDQVYA CCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCEEECCHHHCCCEEE VNLRGAVLGIKAFLPGMLERKEGVIVTITSSEGMPYMASYFASKAALQSLGLSLAGELSE EECCHHHHHHHHHHCHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHCCHH ESGVSAFVFAPGMVDTPGGNQAFQALAPKYGMSYQEFINMSPNPGYNGLMPAEDCAAGFA CCCCEEEEECCCCCCCCCCCHHHHHHCCHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHHH YAIVHARDYHGQIADPFQILAKTGLLQFSSQPKTDNTVPAESSLEKPAGKKSAIELAREV HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH KKILEAVNKEANELDLFRKMWVTRAFRQRTGMSIKDWLETVTELVAELEAAETGDTTKIE HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH NIRGKLPWLKSNLERLADYFKKNMKDAEGYFKDPKALAKALEVLTYRVNTVRSLISALEQ HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH KVKP HCCC >Mature Secondary Structure MLIEKMGLSRTALAGKVAVITGAGQGIGKELARALAWLGAKVIIAEIRDTGAEVETLIRS CCCCCCCCCHHHHCCEEEEEECCCCCHHHHHHHHHHHHHHHHHEEHHHHCCHHHHHHHHC EGGTAMFVQTDVSDEKSIQALAKKAFNTFGKVDILVNNAIIYRPGTILELPIEAWDQVYA CCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCEEECCHHHCCCEEE VNLRGAVLGIKAFLPGMLERKEGVIVTITSSEGMPYMASYFASKAALQSLGLSLAGELSE EECCHHHHHHHHHHCHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCHHHHCCHH ESGVSAFVFAPGMVDTPGGNQAFQALAPKYGMSYQEFINMSPNPGYNGLMPAEDCAAGFA CCCCEEEEECCCCCCCCCCCHHHHHHCCHHCCCHHHHCCCCCCCCCCCCCCHHHHHHHHH YAIVHARDYHGQIADPFQILAKTGLLQFSSQPKTDNTVPAESSLEKPAGKKSAIELAREV HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH KKILEAVNKEANELDLFRKMWVTRAFRQRTGMSIKDWLETVTELVAELEAAETGDTTKIE HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHH NIRGKLPWLKSNLERLADYFKKNMKDAEGYFKDPKALAKALEVLTYRVNTVRSLISALEQ HHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH KVKP HCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9655913; 12597275 [H]