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The map label for this gene is thrS [H]

Identifier: 239616791

GI number: 239616791

Start: 402618

End: 404282

Strand: Direct

Name: thrS [H]

Synonym: Kole_0384

Alternate gene names: 239616791

Gene position: 402618-404282 (Clockwise)

Preceding gene: 239616790

Following gene: 239616792

Centisome position: 17.49

GC content: 40.54

Gene sequence:

>1665_bases
TTGGAAAATATCAAAGTTAAAATCAACAAACTCAACACCGAAATTGAGGTGCCGAAGGGAATAGCTTTTTATGAACTCGC
CGAAAGGTTTCAAAAGCACTACGATTCTCCCATAATGGCTGCAAGAATGGAGAACTCCCTTGTTGAGTTGCGAAGAAAGC
TAGAAAAAGACGCGGTAATCGATTTTATTGATCTTTCCAACATCGATGGTATAAGAATCTACACAAGAGGAATACTTTTC
ATTCTCTTTATGTCTGTCAGGGAGGTTCTTGGAAAAGTCAAGCTTTACGTCCACCATTCGCTGGGTTCCGGCCTGGTTTG
CGAGGTCGTTGGAAAAAACGTGGGAAAGGAAGAACTTGAGAAAATAGAATCAAAGATGCGAGATATCGTTGAACAGGATC
TCCCTTTCTCAAAAGAAACCATCGATAAATTTGAAGCCATCGAACTGTTCAAACTAGATCAACAGATGGAAAAATCTTTG
TTGTTCAAGTACAGAAAAAAGAGTACCGTAAACATCTATAAATGTGATAACTACTTTAATTATTTCTACGGTTATATGCC
CATGTCCACGGGCTGTCTCAAACACTTTGAACTCTTGCCCTATGGAGAATATTTCATTCTGAACCTTCCCACCCCTTCAT
CTCCAAACAAAGTTCCAGCGTTTGTTGATCAGCCAAAGCTGGCCTCAATATTCATGGAGCATGAACACTGGGGGAAAATC
TTAAATGTCAAAACTGTTGGAGAACTGAACAAGATAATAGCAAAAGGTCCTGACAGCATAGCTGAACTGATAAAAATAGC
CGAGGTTCTTCACGAGAAGAAAATAGCTTACATTGCTGATAAAATAGTTAATAGAAAAGGAACCCGGTTGATCCTAATCG
CTGGACCTTCAAGTTCAGGAAAAACAACCTTTTCGAAACGTCTAATGATCCATTTGCGCGTTCATGGATTGAGACCCGTT
CAGATTTCTCTCGACGATTATTTCGTTGACAGAGAAAAGACACCGAAAGATGAGAACGGCGAGTATGATTTCGAATCCAT
ATATGCCCTTGATCTGGAGCTATTTAATCAGCAGATGACCGAACTGCTCGCGGGTAAAGAGGTCCACCTTTCTCGTTTCA
ATTTTAAGGAAGGTCGTCGATACTTTAGAGATGAAACCGTGAAAATCGAAGAAGATCAACCGATTATTGTAGAAGGCATT
CACGGACTCAACGAACTCCTTACAAGTTCCATTCCACGGGAAAAGAAGTTCAAGGTCTATGTCAGTGCTCTAACACAGAT
GAACCTTGATGACATGAACCGAATACCAACAACCGACGTCAGACTTTTAAGGAGAATTGTTCGCGATCACAAATTCCGGG
GCCACCCGGCTCAACAAACAATACATATGTGGGGTAGTGTGAGAAGAGGAGAGGAGAGAAATATTTTCCCATTCCAGGAA
GAAGCTGATGTAATGTTCAACTCAGCACTGGTTTACGAACTAGCTGTATTGAAAATGTTCGCAGAACCCTTACTCTTAGA
AATAGACAACAGCGTCCCTGAATATTCAGAGGTAAAACGCTTGCTGAGATTTATAGATTACTTTTTACCAATAACCAATC
TTGAAGAAATTCCGAGAACTTCCATAATCAGGGAATTCATCGGAGGGAGTTCTTTCAAGTATTAA

Upstream 100 bases:

>100_bases
ATGCCTTACCAGCTTGGCTACGCCCCAATGCAAAACTAATTGTAGCATTGCTAAATGATACTGTCAAGAACGCAATAACC
TGACCATGGGGGTGAATAAA

Downstream 100 bases:

>100_bases
AGTGAGGTGGACACGGTGAACGAGAACATCTCAAAAGATGACCTCATCAAACGTCTAAGACGAATAGAAGGGCAAATCAG
AGGACTTCAGAGAATGATTG

Product: Phosphoribulokinase / Uridine kinase family protein

Products: NA

Alternate protein names: Threonine--tRNA ligase; ThrRS [H]

Number of amino acids: Translated: 554; Mature: 554

Protein sequence:

>554_residues
MENIKVKINKLNTEIEVPKGIAFYELAERFQKHYDSPIMAARMENSLVELRRKLEKDAVIDFIDLSNIDGIRIYTRGILF
ILFMSVREVLGKVKLYVHHSLGSGLVCEVVGKNVGKEELEKIESKMRDIVEQDLPFSKETIDKFEAIELFKLDQQMEKSL
LFKYRKKSTVNIYKCDNYFNYFYGYMPMSTGCLKHFELLPYGEYFILNLPTPSSPNKVPAFVDQPKLASIFMEHEHWGKI
LNVKTVGELNKIIAKGPDSIAELIKIAEVLHEKKIAYIADKIVNRKGTRLILIAGPSSSGKTTFSKRLMIHLRVHGLRPV
QISLDDYFVDREKTPKDENGEYDFESIYALDLELFNQQMTELLAGKEVHLSRFNFKEGRRYFRDETVKIEEDQPIIVEGI
HGLNELLTSSIPREKKFKVYVSALTQMNLDDMNRIPTTDVRLLRRIVRDHKFRGHPAQQTIHMWGSVRRGEERNIFPFQE
EADVMFNSALVYELAVLKMFAEPLLLEIDNSVPEYSEVKRLLRFIDYFLPITNLEEIPRTSIIREFIGGSSFKY

Sequences:

>Translated_554_residues
MENIKVKINKLNTEIEVPKGIAFYELAERFQKHYDSPIMAARMENSLVELRRKLEKDAVIDFIDLSNIDGIRIYTRGILF
ILFMSVREVLGKVKLYVHHSLGSGLVCEVVGKNVGKEELEKIESKMRDIVEQDLPFSKETIDKFEAIELFKLDQQMEKSL
LFKYRKKSTVNIYKCDNYFNYFYGYMPMSTGCLKHFELLPYGEYFILNLPTPSSPNKVPAFVDQPKLASIFMEHEHWGKI
LNVKTVGELNKIIAKGPDSIAELIKIAEVLHEKKIAYIADKIVNRKGTRLILIAGPSSSGKTTFSKRLMIHLRVHGLRPV
QISLDDYFVDREKTPKDENGEYDFESIYALDLELFNQQMTELLAGKEVHLSRFNFKEGRRYFRDETVKIEEDQPIIVEGI
HGLNELLTSSIPREKKFKVYVSALTQMNLDDMNRIPTTDVRLLRRIVRDHKFRGHPAQQTIHMWGSVRRGEERNIFPFQE
EADVMFNSALVYELAVLKMFAEPLLLEIDNSVPEYSEVKRLLRFIDYFLPITNLEEIPRTSIIREFIGGSSFKY
>Mature_554_residues
MENIKVKINKLNTEIEVPKGIAFYELAERFQKHYDSPIMAARMENSLVELRRKLEKDAVIDFIDLSNIDGIRIYTRGILF
ILFMSVREVLGKVKLYVHHSLGSGLVCEVVGKNVGKEELEKIESKMRDIVEQDLPFSKETIDKFEAIELFKLDQQMEKSL
LFKYRKKSTVNIYKCDNYFNYFYGYMPMSTGCLKHFELLPYGEYFILNLPTPSSPNKVPAFVDQPKLASIFMEHEHWGKI
LNVKTVGELNKIIAKGPDSIAELIKIAEVLHEKKIAYIADKIVNRKGTRLILIAGPSSSGKTTFSKRLMIHLRVHGLRPV
QISLDDYFVDREKTPKDENGEYDFESIYALDLELFNQQMTELLAGKEVHLSRFNFKEGRRYFRDETVKIEEDQPIIVEGI
HGLNELLTSSIPREKKFKVYVSALTQMNLDDMNRIPTTDVRLLRRIVRDHKFRGHPAQQTIHMWGSVRRGEERNIFPFQE
EADVMFNSALVYELAVLKMFAEPLLLEIDNSVPEYSEVKRLLRFIDYFLPITNLEEIPRTSIIREFIGGSSFKY

Specific function: Pyrimidine salvage pathway. [C]

COG id: COG0572

COG function: function code F; Uridine kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002314
- InterPro:   IPR006195
- InterPro:   IPR004154
- InterPro:   IPR012675
- InterPro:   IPR004095
- InterPro:   IPR012676
- InterPro:   IPR002320
- InterPro:   IPR018163
- InterPro:   IPR012947 [H]

Pfam domain/function: PF03129 HGTP_anticodon; PF02824 TGS; PF00587 tRNA-synt_2b; PF07973 tRNA_SAD [H]

EC number: =6.1.1.3 [H]

Molecular weight: Translated: 64435; Mature: 64435

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENIKVKINKLNTEIEVPKGIAFYELAERFQKHYDSPIMAARMENSLVELRRKLEKDAVI
CCCEEEEEEEECCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEE
DFIDLSNIDGIRIYTRGILFILFMSVREVLGKVKLYVHHSLGSGLVCEVVGKNVGKEELE
EEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHCCCCCHHHHH
KIESKMRDIVEQDLPFSKETIDKFEAIELFKLDQQMEKSLLFKYRKKSTVNIYKCDNYFN
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
YFYGYMPMSTGCLKHFELLPYGEYFILNLPTPSSPNKVPAFVDQPKLASIFMEHEHWGKI
HHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCE
LNVKTVGELNKIIAKGPDSIAELIKIAEVLHEKKIAYIADKIVNRKGTRLILIAGPSSSG
EEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
KTTFSKRLMIHLRVHGLRPVQISLDDYFVDREKTPKDENGEYDFESIYALDLELFNQQMT
CCHHHHEEEEEEEECCCCEEEEEHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ELLAGKEVHLSRFNFKEGRRYFRDETVKIEEDQPIIVEGIHGLNELLTSSIPREKKFKVY
HHHCCCCEEEECCCHHHHHHHHCCCCEEECCCCCEEEHHHHHHHHHHHCCCCCCHHHHHH
VSALTQMNLDDMNRIPTTDVRLLRRIVRDHKFRGHPAQQTIHMWGSVRRGEERNIFPFQE
HHHHHHCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCH
EADVMFNSALVYELAVLKMFAEPLLLEIDNSVPEYSEVKRLLRFIDYFLPITNLEEIPRT
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHCCHH
SIIREFIGGSSFKY
HHHHHHHCCCCCCC
>Mature Secondary Structure
MENIKVKINKLNTEIEVPKGIAFYELAERFQKHYDSPIMAARMENSLVELRRKLEKDAVI
CCCEEEEEEEECCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEE
DFIDLSNIDGIRIYTRGILFILFMSVREVLGKVKLYVHHSLGSGLVCEVVGKNVGKEELE
EEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCHHHHHHCCCCCHHHHH
KIESKMRDIVEQDLPFSKETIDKFEAIELFKLDQQMEKSLLFKYRKKSTVNIYKCDNYFN
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCHHH
YFYGYMPMSTGCLKHFELLPYGEYFILNLPTPSSPNKVPAFVDQPKLASIFMEHEHWGKI
HHHHHCCCCHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCE
LNVKTVGELNKIIAKGPDSIAELIKIAEVLHEKKIAYIADKIVNRKGTRLILIAGPSSSG
EEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCC
KTTFSKRLMIHLRVHGLRPVQISLDDYFVDREKTPKDENGEYDFESIYALDLELFNQQMT
CCHHHHEEEEEEEECCCCEEEEEHHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ELLAGKEVHLSRFNFKEGRRYFRDETVKIEEDQPIIVEGIHGLNELLTSSIPREKKFKVY
HHHCCCCEEEECCCHHHHHHHHCCCCEEECCCCCEEEHHHHHHHHHHHCCCCCCHHHHHH
VSALTQMNLDDMNRIPTTDVRLLRRIVRDHKFRGHPAQQTIHMWGSVRRGEERNIFPFQE
HHHHHHCCHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCH
EADVMFNSALVYELAVLKMFAEPLLLEIDNSVPEYSEVKRLLRFIDYFLPITNLEEIPRT
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHCCHH
SIIREFIGGSSFKY
HHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA