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The map label for this gene is prsA [H]

Identifier: 239616790

GI number: 239616790

Start: 400386

End: 402407

Strand: Direct

Name: prsA [H]

Synonym: Kole_0383

Alternate gene names: 239616790

Gene position: 400386-402407 (Clockwise)

Preceding gene: 239616789

Following gene: 239616791

Centisome position: 17.39

GC content: 37.98

Gene sequence:

>2022_bases
ATGCATGAAACAAGATGGATGAGAAAAATTCAGGTACCGATCATCTGGACGATCGCTATACTTTTTGCTGCCGGGGTTAT
CTGGTGGTCAGTGGCAACCTATATGTCCGGTAAAAGTCGTGAAACTGGAAGCACGACACCCACCAACAGTGCAAGACCCG
AGGACGCCTTTGCGTATCTTACCAAAGACGGTACCCCCCTCGAAGATCCTATTTACTGGATCTCTTATTCTGAATATGAT
GATACTGTTAGAGATGTTTTATCCAGTCTAAGTCAACGGAACATACAGCTTGATCCTTATTTCAAAGGTTCGGCTGGAAT
GAGCGAGATCGATGTTCGATATATGGTTCTTCTTGATTTAATCGATCAAAAAATACTCATATATTACGCAAAGAAGCACA
ACATCTATCCAACAGAAGATGAGATAAACACCAGGGTTGAGGAAATAGTTTCTAAATATACCAGCGATGAAAATTACAAA
GCACAAATAGAGCAATATTACGGTTCTGTTGAGGCTTTCAAGGAAAAGGTCAGAAAAAGTATTTTCCCTTCAGTGTTAAA
GGAAAAGGTTCAGAACGATGTCTTGAAAGATGTTGATCAAAAACTAAAGACTTATTTTGAGGAAAACAAAGATGAGATAA
AGAACAAATACGAACGGGTTGAAGCAAGTCACATACTCTTGACTTCAGAAGCCAGTGCTCTGGAACTAAAAAATGAGCTT
TTAAACGGTGCAATTAATTTTTCAGATGCAGCAAGTGAATTTTCTATCGATAGGAATTCAGCTGTTCTGGGCGGAAGTCT
TGGAAGTTTTGGACACGGACAGATGGTAAAGGAATTCGAAGATGCTGCTTTCTCAGCAACCCCCGGAGAAATTGTTGGGC
CGGTTGAGACTAAATACGGTTTCCATCTGATAAAAGTTGCAACCAAAACAGTTTTCGATACTTTCGATGAACTTAAGTCA
AGCAGCGCTTACGATCAGTTCAAAAATGATTATGAAAGTGACGAATTTAAAAAATGGTTTGAGAATTACAAGAATAACGA
AAAATTCGGATATGTTATAAACGACGAAGAATTGAAAATCTACAACGAATTTAAAAAAGTCCAGAATGCTGGAAATACCG
ATGAATATCTCAAAAAATTGAGTACCACCATTTTCAACGAAAGTGGTGGAATTTCGGTTGAAGGTAGTTATTTGCCAATT
GCAATCTTTGTGCAACTTTCAGATGAAAAACTAAACAACCTGAAATATGAACTCAACGACCTTAAAGAAATGAAAAAGTT
GAGCGAAACCACACCTGCTACTATTTTGTCCTTGAGTAATGAAGAGATTGAGAAAAAACTATCAGAACTCAATGACAGCA
CAGATACGAAGTTGAAAGATCTATACAGCGACGCAAAAAAATTGAAGGAATATCAATCTAAGTACGGCGAAGATATAAAT
TCTGTGAATGAATTACTGGAAACAAAACAAAAGGAATTTGACGAACTGAACAGCAGATTTGCTACAGCCGTGAAGTTTCT
TTACAACATGATGCCCTATTCCTTCGAGGTATTGAACTACATGTATCGTGTCGATTCTGAAAATCCAGAGGTTGTCCTAA
GATACAATGAAGGTGTGTACACTCATAATTTAAAACCATTACTGGATAGTCCAAGCACTTTACAGAGTTATCTTGATTAT
TACAAACAGCAACTTGGTGATAATGCGAGAATGTTTCTTATAGACTATCCGCTGCAGAAGATAGAGAGGGATTTGAATAC
CAAAATTATAAATGCAACCAATGCGGCAACAGATTTGAAGGTTTCAGCCCTTTACCTGCTTGTGGATGCTTACGAAAAAT
TAGCATCCTTGCCGGATCAAAACAACATCCTGGTTGAACTGTACTTGAGAGGTGAAAAACGTTATCTAAACGAGCTGAAA
AAACTTCTCCCAAACGATAATGATGTTGCGTCTAAGCTTGAATTCGTAGAAAAGCAAATTGAAGAACTTCAGCAAGAAAC
AACCCCACCGGCCACTGAGTAA

Upstream 100 bases:

>100_bases
ATGATATAATCCGTAAAGTCAGGGGAGGTTAATCGCCTCCCCTTGTTGGTTGAGGTTTTGTGAGGAAATATAATGGTGTG
TGGAGGGAGTTGAAGAACCA

Downstream 100 bases:

>100_bases
TAAAAAATTCGGGGTGGCCTGAAAGCCACCCCGAATTTTTCTAAACGTGCTTTTTGTTTTTTGGCTGGGGCGGGAGGATT
CGAACCTCCGGATGTCAGAT

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 673; Mature: 673

Protein sequence:

>673_residues
MHETRWMRKIQVPIIWTIAILFAAGVIWWSVATYMSGKSRETGSTTPTNSARPEDAFAYLTKDGTPLEDPIYWISYSEYD
DTVRDVLSSLSQRNIQLDPYFKGSAGMSEIDVRYMVLLDLIDQKILIYYAKKHNIYPTEDEINTRVEEIVSKYTSDENYK
AQIEQYYGSVEAFKEKVRKSIFPSVLKEKVQNDVLKDVDQKLKTYFEENKDEIKNKYERVEASHILLTSEASALELKNEL
LNGAINFSDAASEFSIDRNSAVLGGSLGSFGHGQMVKEFEDAAFSATPGEIVGPVETKYGFHLIKVATKTVFDTFDELKS
SSAYDQFKNDYESDEFKKWFENYKNNEKFGYVINDEELKIYNEFKKVQNAGNTDEYLKKLSTTIFNESGGISVEGSYLPI
AIFVQLSDEKLNNLKYELNDLKEMKKLSETTPATILSLSNEEIEKKLSELNDSTDTKLKDLYSDAKKLKEYQSKYGEDIN
SVNELLETKQKEFDELNSRFATAVKFLYNMMPYSFEVLNYMYRVDSENPEVVLRYNEGVYTHNLKPLLDSPSTLQSYLDY
YKQQLGDNARMFLIDYPLQKIERDLNTKIINATNAATDLKVSALYLLVDAYEKLASLPDQNNILVELYLRGEKRYLNELK
KLLPNDNDVASKLEFVEKQIEELQQETTPPATE

Sequences:

>Translated_673_residues
MHETRWMRKIQVPIIWTIAILFAAGVIWWSVATYMSGKSRETGSTTPTNSARPEDAFAYLTKDGTPLEDPIYWISYSEYD
DTVRDVLSSLSQRNIQLDPYFKGSAGMSEIDVRYMVLLDLIDQKILIYYAKKHNIYPTEDEINTRVEEIVSKYTSDENYK
AQIEQYYGSVEAFKEKVRKSIFPSVLKEKVQNDVLKDVDQKLKTYFEENKDEIKNKYERVEASHILLTSEASALELKNEL
LNGAINFSDAASEFSIDRNSAVLGGSLGSFGHGQMVKEFEDAAFSATPGEIVGPVETKYGFHLIKVATKTVFDTFDELKS
SSAYDQFKNDYESDEFKKWFENYKNNEKFGYVINDEELKIYNEFKKVQNAGNTDEYLKKLSTTIFNESGGISVEGSYLPI
AIFVQLSDEKLNNLKYELNDLKEMKKLSETTPATILSLSNEEIEKKLSELNDSTDTKLKDLYSDAKKLKEYQSKYGEDIN
SVNELLETKQKEFDELNSRFATAVKFLYNMMPYSFEVLNYMYRVDSENPEVVLRYNEGVYTHNLKPLLDSPSTLQSYLDY
YKQQLGDNARMFLIDYPLQKIERDLNTKIINATNAATDLKVSALYLLVDAYEKLASLPDQNNILVELYLRGEKRYLNELK
KLLPNDNDVASKLEFVEKQIEELQQETTPPATE
>Mature_673_residues
MHETRWMRKIQVPIIWTIAILFAAGVIWWSVATYMSGKSRETGSTTPTNSARPEDAFAYLTKDGTPLEDPIYWISYSEYD
DTVRDVLSSLSQRNIQLDPYFKGSAGMSEIDVRYMVLLDLIDQKILIYYAKKHNIYPTEDEINTRVEEIVSKYTSDENYK
AQIEQYYGSVEAFKEKVRKSIFPSVLKEKVQNDVLKDVDQKLKTYFEENKDEIKNKYERVEASHILLTSEASALELKNEL
LNGAINFSDAASEFSIDRNSAVLGGSLGSFGHGQMVKEFEDAAFSATPGEIVGPVETKYGFHLIKVATKTVFDTFDELKS
SSAYDQFKNDYESDEFKKWFENYKNNEKFGYVINDEELKIYNEFKKVQNAGNTDEYLKKLSTTIFNESGGISVEGSYLPI
AIFVQLSDEKLNNLKYELNDLKEMKKLSETTPATILSLSNEEIEKKLSELNDSTDTKLKDLYSDAKKLKEYQSKYGEDIN
SVNELLETKQKEFDELNSRFATAVKFLYNMMPYSFEVLNYMYRVDSENPEVVLRYNEGVYTHNLKPLLDSPSTLQSYLDY
YKQQLGDNARMFLIDYPLQKIERDLNTKIINATNAATDLKVSALYLLVDAYEKLASLPDQNNILVELYLRGEKRYLNELK
KLLPNDNDVASKLEFVEKQIEELQQETTPPATE

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF05698 Trigger_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 77525; Mature: 77525

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHETRWMRKIQVPIIWTIAILFAAGVIWWSVATYMSGKSRETGSTTPTNSARPEDAFAYL
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEE
TKDGTPLEDPIYWISYSEYDDTVRDVLSSLSQRNIQLDPYFKGSAGMSEIDVRYMVLLDL
ECCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHH
IDQKILIYYAKKHNIYPTEDEINTRVEEIVSKYTSDENYKAQIEQYYGSVEAFKEKVRKS
HCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHH
IFPSVLKEKVQNDVLKDVDQKLKTYFEENKDEIKNKYERVEASHILLTSEASALELKNEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCHHHHHHHHHH
LNGAINFSDAASEFSIDRNSAVLGGSLGSFGHGQMVKEFEDAAFSATPGEIVGPVETKYG
HHCCCCCCCCHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
FHLIKVATKTVFDTFDELKSSSAYDQFKNDYESDEFKKWFENYKNNEKFGYVINDEELKI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCHHHH
YNEFKKVQNAGNTDEYLKKLSTTIFNESGGISVEGSYLPIAIFVQLSDEKLNNLKYELND
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEEEEEEECCHHHHHHHHHHHH
LKEMKKLSETTPATILSLSNEEIEKKLSELNDSTDTKLKDLYSDAKKLKEYQSKYGEDIN
HHHHHHHHCCCCHHEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
SVNELLETKQKEFDELNSRFATAVKFLYNMMPYSFEVLNYMYRVDSENPEVVLRYNEGVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCEE
THNLKPLLDSPSTLQSYLDYYKQQLGDNARMFLIDYPLQKIERDLNTKIINATNAATDLK
ECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCEEEECCCCCCHHH
VSALYLLVDAYEKLASLPDQNNILVELYLRGEKRYLNELKKLLPNDNDVASKLEFVEKQI
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EELQQETTPPATE
HHHHHHCCCCCCC
>Mature Secondary Structure
MHETRWMRKIQVPIIWTIAILFAAGVIWWSVATYMSGKSRETGSTTPTNSARPEDAFAYL
CCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEE
TKDGTPLEDPIYWISYSEYDDTVRDVLSSLSQRNIQLDPYFKGSAGMSEIDVRYMVLLDL
ECCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHHHHH
IDQKILIYYAKKHNIYPTEDEINTRVEEIVSKYTSDENYKAQIEQYYGSVEAFKEKVRKS
HCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHHHHHH
IFPSVLKEKVQNDVLKDVDQKLKTYFEENKDEIKNKYERVEASHILLTSEASALELKNEL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHEEEECCHHHHHHHHHH
LNGAINFSDAASEFSIDRNSAVLGGSLGSFGHGQMVKEFEDAAFSATPGEIVGPVETKYG
HHCCCCCCCCHHHCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
FHLIKVATKTVFDTFDELKSSSAYDQFKNDYESDEFKKWFENYKNNEKFGYVINDEELKI
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHCCCCCCEEEEECCCHHHH
YNEFKKVQNAGNTDEYLKKLSTTIFNESGGISVEGSYLPIAIFVQLSDEKLNNLKYELND
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEEECCEEEEEEEEEECCHHHHHHHHHHHH
LKEMKKLSETTPATILSLSNEEIEKKLSELNDSTDTKLKDLYSDAKKLKEYQSKYGEDIN
HHHHHHHHCCCCHHEEECCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHH
SVNELLETKQKEFDELNSRFATAVKFLYNMMPYSFEVLNYMYRVDSENPEVVLRYNEGVY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEECCCEE
THNLKPLLDSPSTLQSYLDYYKQQLGDNARMFLIDYPLQKIERDLNTKIINATNAATDLK
ECCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCEEEECCCCCCHHH
VSALYLLVDAYEKLASLPDQNNILVELYLRGEKRYLNELKKLLPNDNDVASKLEFVEKQI
HHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EELQQETTPPATE
HHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA