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The map label for this gene is pgi [H]

Identifier: 239616586

GI number: 239616586

Start: 200200

End: 201561

Strand: Reverse

Name: pgi [H]

Synonym: Kole_0178

Alternate gene names: 239616586

Gene position: 201561-200200 (Counterclockwise)

Preceding gene: 239616587

Following gene: 239616585

Centisome position: 8.76

GC content: 45.23

Gene sequence:

>1362_bases
ATGCTAAAGTTTGATTTTTCCTTCGCCTTTAAAGAGAATCTAGGAACAGGTCTTTCAAAGGATGAGGTTTTTAATAACAG
GGAATTCGCCAAAAGATCTCTTTTGGATGTAATCGAATCAGAGCCGGGATTTCTGAGGATCCTCAAAACCGATGAATATC
TTGATGAGGTTGAAGCCCTGAAGGATTGGGTAAAAAACTTTGATACGCTTGTTGTTGTGGGAATCGGTGGTTCGGCTCTC
GGTAACCTTGCACTTCATGCATCTTTGAAGCCCATGAACTGGAACCTTCTGAGCGAGGAAGAAAGAGAAGGAAATCTCAG
GGTATTTGTCGTTGATAATGTTGATCCGCATTTTGTTGGCAGCGTTATTGAACAGATCGATCTTGACCGAACGCTGTTTA
ACGTTATTTCCAAATCCGGAACGACAGCTGAAGCCATGGCGAATTATCTCGTGGTGAGAGGAATACTCGAAAAGCGAGGA
TTAGATATAAGCGAACACCTGATTTTCACCACCGATCCTGAGAAAGGAGTCTTGCGGCAGATAGCGAAAGAAGAAGGCAT
AAGGACACTGACTATCCCTCAGGATGTTGGCGGACGTTTCAGTGTGTTGACACCCGTTGGGCTATTTTCTGCCATGGCTG
AAGGAATAGATATAAGAAAGCTCTATGAAGGCGCTCGTAACGGTGTCAAACGTTATTCTGAGAGCAGTGCCGATACCAAT
CCTGTTCTGGTAAACGCGCTTCTCCATTATTCTTATCTGAAAGATGGAAAAAGCATCTCTGTTATGATGCCTTACTCGAA
TCAGCTTTACCTTCTTGCGGACTGGTACAGGCAGCTGTGGGCTGAATCGTTGGGAAAGAAGTACGATCTGGATGGAAATG
TGGTTAATACCGGTCAAACTCCGGTAAAGGCCCTTGGTGCTGTGGATCAGCACTCACAGATTCAGCTGTACAACGAGGGG
CCCAAGGATAAGATAGTCACCTTTTTAAAGCTTGAGAAATTCCCGGGGGATTTACAGATTCCCGAGCTTCATTCTGAAAT
TGAAGCGCTGTCGTATCTTGGTGGGAAAAGTCTATCGGAGCTTCTCAACTCAGAACAGGAAGGTACGGCCATGGCACTGA
CTGAAAACGGTGTACCGAATCTCACGTTGAGATTCGACGAACTGTCAGAATCCAGCGTTGGAGAGTTTATCATATATTAT
GAGCTTCTGACCGCTGTAATGGGGGCAATGCTCAACATAAATCCTTACGATCAGCCCGGCGTCGAGCTTGGAAAAAAGAT
CACCTATTCGCTCATGGGAAGAAAAGGGTACGAAGCCTTTGCCGGCAAGTTTTCTGAGAAAAAGTGGAGGTTCGAATTAT
GA

Upstream 100 bases:

>100_bases
GGAATAGTATCTCTGGTCGAACTTTCCTTCCTTGAACCAAGAAAGAAACTTTCAGGTTATGAAGTGAGAAGCATCATAAC
CTATTGAGGTGAGGTTCTAT

Downstream 100 bases:

>100_bases
ACGATATGGTTAATTATCTGGTGGAATGCCTTAAAGAGTATAAACTTGAGGAATTCTACCATTTAGAAGGAGACGAAGTA
CCTTTCTATGTAATAGTTTC

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MLKFDFSFAFKENLGTGLSKDEVFNNREFAKRSLLDVIESEPGFLRILKTDEYLDEVEALKDWVKNFDTLVVVGIGGSAL
GNLALHASLKPMNWNLLSEEEREGNLRVFVVDNVDPHFVGSVIEQIDLDRTLFNVISKSGTTAEAMANYLVVRGILEKRG
LDISEHLIFTTDPEKGVLRQIAKEEGIRTLTIPQDVGGRFSVLTPVGLFSAMAEGIDIRKLYEGARNGVKRYSESSADTN
PVLVNALLHYSYLKDGKSISVMMPYSNQLYLLADWYRQLWAESLGKKYDLDGNVVNTGQTPVKALGAVDQHSQIQLYNEG
PKDKIVTFLKLEKFPGDLQIPELHSEIEALSYLGGKSLSELLNSEQEGTAMALTENGVPNLTLRFDELSESSVGEFIIYY
ELLTAVMGAMLNINPYDQPGVELGKKITYSLMGRKGYEAFAGKFSEKKWRFEL

Sequences:

>Translated_453_residues
MLKFDFSFAFKENLGTGLSKDEVFNNREFAKRSLLDVIESEPGFLRILKTDEYLDEVEALKDWVKNFDTLVVVGIGGSAL
GNLALHASLKPMNWNLLSEEEREGNLRVFVVDNVDPHFVGSVIEQIDLDRTLFNVISKSGTTAEAMANYLVVRGILEKRG
LDISEHLIFTTDPEKGVLRQIAKEEGIRTLTIPQDVGGRFSVLTPVGLFSAMAEGIDIRKLYEGARNGVKRYSESSADTN
PVLVNALLHYSYLKDGKSISVMMPYSNQLYLLADWYRQLWAESLGKKYDLDGNVVNTGQTPVKALGAVDQHSQIQLYNEG
PKDKIVTFLKLEKFPGDLQIPELHSEIEALSYLGGKSLSELLNSEQEGTAMALTENGVPNLTLRFDELSESSVGEFIIYY
ELLTAVMGAMLNINPYDQPGVELGKKITYSLMGRKGYEAFAGKFSEKKWRFEL
>Mature_453_residues
MLKFDFSFAFKENLGTGLSKDEVFNNREFAKRSLLDVIESEPGFLRILKTDEYLDEVEALKDWVKNFDTLVVVGIGGSAL
GNLALHASLKPMNWNLLSEEEREGNLRVFVVDNVDPHFVGSVIEQIDLDRTLFNVISKSGTTAEAMANYLVVRGILEKRG
LDISEHLIFTTDPEKGVLRQIAKEEGIRTLTIPQDVGGRFSVLTPVGLFSAMAEGIDIRKLYEGARNGVKRYSESSADTN
PVLVNALLHYSYLKDGKSISVMMPYSNQLYLLADWYRQLWAESLGKKYDLDGNVVNTGQTPVKALGAVDQHSQIQLYNEG
PKDKIVTFLKLEKFPGDLQIPELHSEIEALSYLGGKSLSELLNSEQEGTAMALTENGVPNLTLRFDELSESSVGEFIIYY
ELLTAVMGAMLNINPYDQPGVELGKKITYSLMGRKGYEAFAGKFSEKKWRFEL

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Escherichia coli, GI1790457, Length=388, Percent_Identity=28.3505154639175, Blast_Score=110, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71996708, Length=433, Percent_Identity=26.5588914549654, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI71996703, Length=433, Percent_Identity=26.5588914549654, Blast_Score=92, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6319673, Length=384, Percent_Identity=28.6458333333333, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24651916, Length=399, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24651914, Length=399, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17737445, Length=399, Percent_Identity=26.3157894736842, Blast_Score=92, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 50641; Mature: 50641

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKFDFSFAFKENLGTGLSKDEVFNNREFAKRSLLDVIESEPGFLRILKTDEYLDEVEAL
CEEEEEEHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHH
KDWVKNFDTLVVVGIGGSALGNLALHASLKPMNWNLLSEEEREGNLRVFVVDNVDPHFVG
HHHHCCCCEEEEEECCCHHHCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHH
SVIEQIDLDRTLFNVISKSGTTAEAMANYLVVRGILEKRGLDISEHLIFTTDPEKGVLRQ
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHCEEEECCCCHHHHHH
IAKEEGIRTLTIPQDVGGRFSVLTPVGLFSAMAEGIDIRKLYEGARNGVKRYSESSADTN
HHHHCCCEEEECCCCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
PVLVNALLHYSYLKDGKSISVMMPYSNQLYLLADWYRQLWAESLGKKYDLDGNVVNTGQT
HHHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHHHHHHHHHHHCCCEECCCCCEEECCCC
PVKALGAVDQHSQIQLYNEGPKDKIVTFLKLEKFPGDLQIPELHSEIEALSYLGGKSLSE
HHHHHCCCCCCCEEEEECCCCHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHH
LLNSEQEGTAMALTENGVPNLTLRFDELSESSVGEFIIYYELLTAVMGAMLNINPYDQPG
HHCCCCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCH
VELGKKITYSLMGRKGYEAFAGKFSEKKWRFEL
HHHHHHHHHHHHCCCCHHHHHCCCCCCCEEECC
>Mature Secondary Structure
MLKFDFSFAFKENLGTGLSKDEVFNNREFAKRSLLDVIESEPGFLRILKTDEYLDEVEAL
CEEEEEEHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHCCCCEEEEEECHHHHHHHHHH
KDWVKNFDTLVVVGIGGSALGNLALHASLKPMNWNLLSEEEREGNLRVFVVDNVDPHFVG
HHHHCCCCEEEEEECCCHHHCCEEEEEECCCCCCCCCCCCCCCCCEEEEEECCCCHHHHH
SVIEQIDLDRTLFNVISKSGTTAEAMANYLVVRGILEKRGLDISEHLIFTTDPEKGVLRQ
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHCEEEECCCCHHHHHH
IAKEEGIRTLTIPQDVGGRFSVLTPVGLFSAMAEGIDIRKLYEGARNGVKRYSESSADTN
HHHHCCCEEEECCCCCCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCC
PVLVNALLHYSYLKDGKSISVMMPYSNQLYLLADWYRQLWAESLGKKYDLDGNVVNTGQT
HHHHHHHHHHHHHCCCCEEEEEECCCCCEEEHHHHHHHHHHHHCCCEECCCCCEEECCCC
PVKALGAVDQHSQIQLYNEGPKDKIVTFLKLEKFPGDLQIPELHSEIEALSYLGGKSLSE
HHHHHCCCCCCCEEEEECCCCHHHHEEEEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHH
LLNSEQEGTAMALTENGVPNLTLRFDELSESSVGEFIIYYELLTAVMGAMLNINPYDQPG
HHCCCCCCCEEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCH
VELGKKITYSLMGRKGYEAFAGKFSEKKWRFEL
HHHHHHHHHHHHCCCCHHHHHCCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]