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The map label for this gene is glpA [C]

Identifier: 239616567

GI number: 239616567

Start: 175370

End: 176815

Strand: Reverse

Name: glpA [C]

Synonym: Kole_0159

Alternate gene names: 239616567

Gene position: 176815-175370 (Counterclockwise)

Preceding gene: 239616577

Following gene: 239616566

Centisome position: 7.68

GC content: 44.26

Gene sequence:

>1446_bases
GTGAGATTCGCGATAATTGGTGGTGGCGTTATTGGCAGCTTAATAGCCTGGAAACTTTCAAAATACGATGTGGATGTTGT
GTTAATCGAAAAGAAGTCTGATTTCGGTCAGGGCGTAACTAAAGCAAATTCCGCGATCCTTCATGGAGGTTATGATGATC
CACCAGGGAGTTTGAGAGCGCGTTTCTGTGTGCTGGGTAATCAAATGTATAGAACGTTAAGCCATGAACTTGGTTTTGAG
ATTAAATGGACAGGATCAATAGTGCTGGCAAGAGATACAAATGAAGAGATCGAAAAGTTAAAAGAACTCATGAAAAAGGG
AGAAGAAAATGGCGTAAAAGGGCTTCAAATAATTGATAGAAACGAAATCGAGAAGATTCAACCCGGGATAGCAGAAGATT
ACAAATATGCCTTGTATTGCCCAACAGCCGGGGTTACTGAACCGTGGGAGATAGCGATTAACGCTGCCGATGGAGCGGCC
CTTAATGGAGCGACTCTGATTAGAGGGGACGGAGTTGTTGGTGGTGAGATCATCAACGGTTCTATAAAAACCCTCAAACT
TAGTTCGGGCAAAACAATAAGGGTAGATGTAGTTATAAACGCCGCGGGTCTCTATTATGAACATGTAGCCAATTTATTTG
GAGCAAGAACCCCGAAAGTGTTTTTGAGAAAAGGGCAGTACATTCTTTTAGATAAAATTGTTGGGACACGCGTTGAAAAG
ATTATTTTCCCCCTGCCAAACGAGAAAGGGAAAGGAAAACTTGTCGTTCCCACTGTGGACGGTGGAGTGCTTTTAGGCCC
AACATCGGAGGATCTTCCGGGATTCTCGCCGGAGGATGTTTCTACAACGCTTGATGGAATCAAAGAGGTTATGGAAGCGG
GAGAACAGCTGATGCCCGGGCTTGCAAAAAGGGAATGGGTGATAAAAAGCTTTGCCGGTCTTCGCCCTGAAACGAAAGAA
AAGGACTTTTTCATACAAAGGAGTGAAGAGCTCAGAAACTTCATAACGGTTGGGGCTATCCGATCTCCAGGTCTTACAGC
TGCTCCTGCGATTGCAAAATATGTTGTTGAAGAGATCATTCATGAAGAAATGGGACTTGCACTGACCGGGAAAACCGTGA
TCAAATACCCTGAAAAGAAGACAAGGGTCAAGGAAAAGGATTTCAATGAATTAGCCGAGGAGATTTCCAGAGAACCTTTG
CTTGGAAAGATCATTTGTCATTGTAATCAGGTGTCAGAAAAGGAAATTGTCGAAGCGATTCGTGATGGCGCAACCACGAT
AGATGGGATAAAATTCAGAACCCGTGCTGGCTTTGGAAGGTGCCAGGGAGGTTTTTGCGGCTGGAAGATTGCAAGAATAC
TTGCGAGAGAGTTGAATATCGATATATCGGAGGTTCTGCAGAATGAGGATGAAAGTTGGCTGGTTAGAGAGAAGGTGAGG
CCATGA

Upstream 100 bases:

>100_bases
CAGTCATGTAGTAAAAGATGATATAATAATTTTACCGTGGTGGAGAAGGAGAGAAAACCACGCCAATATTGGCGTGGTTT
TTCTTTTTGGAGGTGAAACA

Downstream 100 bases:

>100_bases
AGAAACTCAAAACAGATGTACTCGTGATAGGCGGTGGAGCGGCCGGGATGGCTGCGGCCATTGGAGCTGCGAGAGAGGGT
TCGAAGGTGATTCTAATTGA

Product: FAD dependent oxidoreductase

Products: glycerone phosphate; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MRFAIIGGGVIGSLIAWKLSKYDVDVVLIEKKSDFGQGVTKANSAILHGGYDDPPGSLRARFCVLGNQMYRTLSHELGFE
IKWTGSIVLARDTNEEIEKLKELMKKGEENGVKGLQIIDRNEIEKIQPGIAEDYKYALYCPTAGVTEPWEIAINAADGAA
LNGATLIRGDGVVGGEIINGSIKTLKLSSGKTIRVDVVINAAGLYYEHVANLFGARTPKVFLRKGQYILLDKIVGTRVEK
IIFPLPNEKGKGKLVVPTVDGGVLLGPTSEDLPGFSPEDVSTTLDGIKEVMEAGEQLMPGLAKREWVIKSFAGLRPETKE
KDFFIQRSEELRNFITVGAIRSPGLTAAPAIAKYVVEEIIHEEMGLALTGKTVIKYPEKKTRVKEKDFNELAEEISREPL
LGKIICHCNQVSEKEIVEAIRDGATTIDGIKFRTRAGFGRCQGGFCGWKIARILARELNIDISEVLQNEDESWLVREKVR
P

Sequences:

>Translated_481_residues
MRFAIIGGGVIGSLIAWKLSKYDVDVVLIEKKSDFGQGVTKANSAILHGGYDDPPGSLRARFCVLGNQMYRTLSHELGFE
IKWTGSIVLARDTNEEIEKLKELMKKGEENGVKGLQIIDRNEIEKIQPGIAEDYKYALYCPTAGVTEPWEIAINAADGAA
LNGATLIRGDGVVGGEIINGSIKTLKLSSGKTIRVDVVINAAGLYYEHVANLFGARTPKVFLRKGQYILLDKIVGTRVEK
IIFPLPNEKGKGKLVVPTVDGGVLLGPTSEDLPGFSPEDVSTTLDGIKEVMEAGEQLMPGLAKREWVIKSFAGLRPETKE
KDFFIQRSEELRNFITVGAIRSPGLTAAPAIAKYVVEEIIHEEMGLALTGKTVIKYPEKKTRVKEKDFNELAEEISREPL
LGKIICHCNQVSEKEIVEAIRDGATTIDGIKFRTRAGFGRCQGGFCGWKIARILARELNIDISEVLQNEDESWLVREKVR
P
>Mature_481_residues
MRFAIIGGGVIGSLIAWKLSKYDVDVVLIEKKSDFGQGVTKANSAILHGGYDDPPGSLRARFCVLGNQMYRTLSHELGFE
IKWTGSIVLARDTNEEIEKLKELMKKGEENGVKGLQIIDRNEIEKIQPGIAEDYKYALYCPTAGVTEPWEIAINAADGAA
LNGATLIRGDGVVGGEIINGSIKTLKLSSGKTIRVDVVINAAGLYYEHVANLFGARTPKVFLRKGQYILLDKIVGTRVEK
IIFPLPNEKGKGKLVVPTVDGGVLLGPTSEDLPGFSPEDVSTTLDGIKEVMEAGEQLMPGLAKREWVIKSFAGLRPETKE
KDFFIQRSEELRNFITVGAIRSPGLTAAPAIAKYVVEEIIHEEMGLALTGKTVIKYPEKKTRVKEKDFNELAEEISREPL
LGKIICHCNQVSEKEIVEAIRDGATTIDGIKFRTRAGFGRCQGGFCGWKIARILARELNIDISEVLQNEDESWLVREKVR
P

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Fumarate Or Nitrate As Electron Acceptor. [C]

COG id: COG0579

COG function: function code R; Predicted dehydrogenase

Gene ontology:

Cell location: Loosely Bound To The Cytoplasm Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI13376331, Length=292, Percent_Identity=28.0821917808219, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI24797151, Length=438, Percent_Identity=25.3424657534247, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1788574, Length=474, Percent_Identity=22.3628691983122, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI87082148, Length=251, Percent_Identity=23.1075697211155, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17565764, Length=409, Percent_Identity=25.4278728606357, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24585081, Length=257, Percent_Identity=27.6264591439689, Blast_Score=89, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.1.99.5

Molecular weight: Translated: 52911; Mature: 52911

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFAIIGGGVIGSLIAWKLSKYDVDVVLIEKKSDFGQGVTKANSAILHGGYDDPPGSLRA
CEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHCCCEEEECCCCCCCHHHHH
RFCVLGNQMYRTLSHELGFEIKWTGSIVLARDTNEEIEKLKELMKKGEENGVKGLQIIDR
HHHHHHHHHHHHHHHHHCEEEEEECEEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEECC
NEIEKIQPGIAEDYKYALYCPTAGVTEPWEIAINAADGAALNGATLIRGDGVVGGEIING
CHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCEEEEECCCEECCEEECC
SIKTLKLSSGKTIRVDVVINAAGLYYEHVANLFGARTPKVFLRKGQYILLDKIVGTRVEK
CEEEEEECCCCEEEEEEEEECCHHHHHHHHHHHCCCCCHHHHHCCCEEEEHHHHHHHHHH
IIFPLPNEKGKGKLVVPTVDGGVLLGPTSEDLPGFSPEDVSTTLDGIKEVMEAGEQLMPG
EEEECCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
LAKREWVIKSFAGLRPETKEKDFFIQRSEELRNFITVGAIRSPGLTAAPAIAKYVVEEII
HHHHHHHHHHHHCCCCCCCCCHHHEECHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHH
HEEMGLALTGKTVIKYPEKKTRVKEKDFNELAEEISREPLLGKIICHCNQVSEKEIVEAI
HHHCCCEEECCCEEECCCHHHHCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHH
RDGATTIDGIKFRTRAGFGRCQGGFCGWKIARILARELNIDISEVLQNEDESWLVREKVR
HCCCCEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHCCC
P
C
>Mature Secondary Structure
MRFAIIGGGVIGSLIAWKLSKYDVDVVLIEKKSDFGQGVTKANSAILHGGYDDPPGSLRA
CEEEEECCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHCCCEEEECCCCCCCHHHHH
RFCVLGNQMYRTLSHELGFEIKWTGSIVLARDTNEEIEKLKELMKKGEENGVKGLQIIDR
HHHHHHHHHHHHHHHHHCEEEEEECEEEEEECCHHHHHHHHHHHHCCCCCCCCCEEEECC
NEIEKIQPGIAEDYKYALYCPTAGVTEPWEIAINAADGAALNGATLIRGDGVVGGEIING
CHHHHHCCCCCCCCCEEEECCCCCCCCCCEEEEECCCCCCCCCEEEEECCCEECCEEECC
SIKTLKLSSGKTIRVDVVINAAGLYYEHVANLFGARTPKVFLRKGQYILLDKIVGTRVEK
CEEEEEECCCCEEEEEEEEECCHHHHHHHHHHHCCCCCHHHHHCCCEEEEHHHHHHHHHH
IIFPLPNEKGKGKLVVPTVDGGVLLGPTSEDLPGFSPEDVSTTLDGIKEVMEAGEQLMPG
EEEECCCCCCCCEEEEEECCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
LAKREWVIKSFAGLRPETKEKDFFIQRSEELRNFITVGAIRSPGLTAAPAIAKYVVEEII
HHHHHHHHHHHHCCCCCCCCCHHHEECHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHH
HEEMGLALTGKTVIKYPEKKTRVKEKDFNELAEEISREPLLGKIICHCNQVSEKEIVEAI
HHHCCCEEECCCEEECCCHHHHCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHH
RDGATTIDGIKFRTRAGFGRCQGGFCGWKIARILARELNIDISEVLQNEDESWLVREKVR
HCCCCEECCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHCCCCCCCHHHHCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: sn-glycerol 3-phosphate; acceptor

Specific reaction: sn-glycerol 3-phosphate + acceptor = glycerone phosphate + reduced acceptor

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7569993 [H]