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The map label for this gene is dapH

Identifier: 239616514

GI number: 239616514

Start: 120265

End: 120963

Strand: Reverse

Name: dapH

Synonym: Kole_0104

Alternate gene names: 239616514

Gene position: 120963-120265 (Counterclockwise)

Preceding gene: 239616515

Following gene: 239616513

Centisome position: 5.25

GC content: 45.21

Gene sequence:

>699_bases
ATGAACGCTGAAACAATAATAAAAATGATAAAGGACTCAAAGAAGAAAACTCCGGCCGTATGTTATGTTAGCGGAAATCT
TGAAGGTCTGGAAACGGGAACACTGAACTTCGTTGGAGGCAAAGACTTCGGTGTGATAATCGGAGATTTCAAGGAAATTC
AGGATCTTATTGCAAGAGAAAGAGAGAGAATAACGGGTTATCACATCGATATTCAGGCTCGAAATTCAGCTCTTCCCCTG
GCAGATTTGACGAAGTATGAGGCGCGTATAGAGCCTGGAGCAATCATCAGGGACCTTGTAGAAATAGGCAAGGGTGCTGT
AATAATGATGGGAGCTGTAATAAATATTGGTGCAGTAATAGGAAAGGGTACAATGATAGATATGAACGCTGTGATCGGTG
GACGCGCCATTATAGGTGACAACTGTCATATAGGCGCCGGAGCCGTAGTGGCCGGGGTTATAGAACCACCCAGCGCAACT
CCGGTAATAATCGAAGACAACGTATTGGTGGGAGCCAATGCTGTGATACTTGAGGGAGTCAGAGTTGGAGCTAACTCCGT
CGTAGCTGCTGGGGCAGTGGTTACAAAAGATGTACCTTCAGGGACAGTAGTGGCCGGAATACCGGCGAAGGTAATTAAAG
CCTTTGATGCTACTACTGCTGACAAGACAAAGATAGTTCAAGACTTGAGAGAACTATAA

Upstream 100 bases:

>100_bases
GGGCGATTTCAAGAAAGGTTTTTGCCATCGGGGCAAAGGAAGCAGCAAACTTTGTGTTGAAAAAAGAAAAAGGCTTTTTC
AGCTATGAAGAGGTGATACT

Downstream 100 bases:

>100_bases
ATATAGAGGAGTTGCTGAAATGCTGGTTCAGAAATATGGCGGCTCATCGGTAGCAACGTTGGAGCGAATAGCTAATGTGG
CAAATAGAATCAAAGCAAGG

Product: Tetrahydrodipicolinate succinyltransferase domain protein

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-acetyltransferase; THP acetyltransferase; Tetrahydropicolinate acetylase

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNAETIIKMIKDSKKKTPAVCYVSGNLEGLETGTLNFVGGKDFGVIIGDFKEIQDLIARERERITGYHIDIQARNSALPL
ADLTKYEARIEPGAIIRDLVEIGKGAVIMMGAVINIGAVIGKGTMIDMNAVIGGRAIIGDNCHIGAGAVVAGVIEPPSAT
PVIIEDNVLVGANAVILEGVRVGANSVVAAGAVVTKDVPSGTVVAGIPAKVIKAFDATTADKTKIVQDLREL

Sequences:

>Translated_232_residues
MNAETIIKMIKDSKKKTPAVCYVSGNLEGLETGTLNFVGGKDFGVIIGDFKEIQDLIARERERITGYHIDIQARNSALPL
ADLTKYEARIEPGAIIRDLVEIGKGAVIMMGAVINIGAVIGKGTMIDMNAVIGGRAIIGDNCHIGAGAVVAGVIEPPSAT
PVIIEDNVLVGANAVILEGVRVGANSVVAAGAVVTKDVPSGTVVAGIPAKVIKAFDATTADKTKIVQDLREL
>Mature_232_residues
MNAETIIKMIKDSKKKTPAVCYVSGNLEGLETGTLNFVGGKDFGVIIGDFKEIQDLIARERERITGYHIDIQARNSALPL
ADLTKYEARIEPGAIIRDLVEIGKGAVIMMGAVINIGAVIGKGTMIDMNAVIGGRAIIGDNCHIGAGAVVAGVIEPPSAT
PVIIEDNVLVGANAVILEGVRVGANSVVAAGAVVTKDVPSGTVVAGIPAKVIKAFDATTADKTKIVQDLREL

Specific function: Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. DapH subfamily

Homologues:

Organism=Escherichia coli, GI1786362, Length=179, Percent_Identity=32.9608938547486, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786664, Length=86, Percent_Identity=47.6744186046512, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1786537, Length=72, Percent_Identity=40.2777777777778, Blast_Score=61, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322243, Length=120, Percent_Identity=37.5, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPH_KOSOT (C5CHX7)

Other databases:

- EMBL:   CP001634
- RefSeq:   YP_002939836.1
- ProteinModelPortal:   C5CHX7
- GeneID:   7967522
- GenomeReviews:   CP001634_GR
- KEGG:   kol:Kole_0104
- ProtClustDB:   CLSK2814015
- HAMAP:   MF_01691
- InterPro:   IPR013710
- InterPro:   IPR001451
- InterPro:   IPR018357
- InterPro:   IPR019873
- InterPro:   IPR011004
- TIGRFAMs:   TIGR03532

Pfam domain/function: PF08503 DapD_N; PF00132 Hexapep; SSF51161 Trimer_LpxA_like

EC number: =2.3.1.89

Molecular weight: Translated: 24081; Mature: 24081

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAETIIKMIKDSKKKTPAVCYVSGNLEGLETGTLNFVGGKDFGVIIGDFKEIQDLIARE
CCHHHHHHHHHCCCCCCCEEEEEECCCCCEECCEEEEECCCCEEEEEECHHHHHHHHHHH
RERITGYHIDIQARNSALPLADLTKYEARIEPGAIIRDLVEIGKGAVIMMGAVINIGAVI
HHHHCEEEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEHHHHHHHEE
GKGTMIDMNAVIGGRAIIGDNCHIGAGAVVAGVIEPPSATPVIIEDNVLVGANAVILEGV
CCCEEEEEEEEECCCEEECCCCCCCCCCEEEEEECCCCCCEEEEECCEEECCCEEEEECE
RVGANSVVAAGAVVTKDVPSGTVVAGIPAKVIKAFDATTADKTKIVQDLREL
EECCCCEEECCEEEECCCCCCCEEECCHHHHHHHHCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MNAETIIKMIKDSKKKTPAVCYVSGNLEGLETGTLNFVGGKDFGVIIGDFKEIQDLIARE
CCHHHHHHHHHCCCCCCCEEEEEECCCCCEECCEEEEECCCCEEEEEECHHHHHHHHHHH
RERITGYHIDIQARNSALPLADLTKYEARIEPGAIIRDLVEIGKGAVIMMGAVINIGAVI
HHHHCEEEEEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHCCCEEEEEEHHHHHHHEE
GKGTMIDMNAVIGGRAIIGDNCHIGAGAVVAGVIEPPSATPVIIEDNVLVGANAVILEGV
CCCEEEEEEEEECCCEEECCCCCCCCCCEEEEEECCCCCCEEEEECCEEECCCEEEEECE
RVGANSVVAAGAVVTKDVPSGTVVAGIPAKVIKAFDATTADKTKIVQDLREL
EECCCCEEECCEEEECCCCCCCEEECCHHHHHHHHCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA