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The map label for this gene is mepA [H]

Identifier: 238925696

GI number: 238925696

Start: 3173133

End: 3173783

Strand: Reverse

Name: mepA [H]

Synonym: EUBREC_3353

Alternate gene names: 238925696

Gene position: 3173783-3173133 (Counterclockwise)

Preceding gene: 238925699

Following gene: 238925695

Centisome position: 92.0

GC content: 46.7

Gene sequence:

>651_bases
ATGGTAATAAAGCTGTACTCCATCGGCATTCCCGCAACCTTGAATATTGCGCTCCCATCTCTTTTGATTTCGGCGCTCAA
TGCAATTTTGGCGGCATATTCCGAAGTGTATATTCTGGTTTTGGGAATATATTACAAATTGCAGACATTCATCTATCTTC
CGGCTAATGGCATTGTTCAGGGGATGCGCCCCTTGATCGGCTATAACTACGGTGCGGGGGAGAATAAAAGAGTCAGCCAG
ATTTATAAAATCGTCTTGTGCATGAGCGGTATCATTATGGTGCTTGGAACAGTGATATGTCTGCTAATCCCCGGCCAGCT
TATGGGGCTGTTTACCCACACAGAAGCGACAATCCAGACCGGGAAAACAGCCCTGCGTATCATCGGCGCCGGTTTTATTG
TCTCGGCGGTTTCCGTTACATCTTCCGGCGCACTGGAGGGACTTGGAAAAGGCATTCCTTCGTTACTGATTTCACTTTGC
CGGTATGTTGTGGTTATCATCCCAACTGCGTTTTTACTCAGCAGCATTTTCGGAGCGGTTGGCGTCTGGAATGCGTTTTG
GATCACGGAAGCGATTACAGCAATCATTTCTATTTGTGTTTACTACAAGGCAATATCACAAAGCCAGCGGAGCCAGTCAA
CAGTAAAATGA

Upstream 100 bases:

>100_bases
CATCGGGCAGACCTTGACGCTTGCGATTTATCTGGTCGTTTATTTTGTGCGGCCAATTCGCGTGCATATCCGCAGGCAGT
ACATTTTGCTCAGCAAAAAG

Downstream 100 bases:

>100_bases
ACGTTGCTTTCTCCCTTGGTGAAAATATCTTTTTTTGATACTGTAATAAAAAGAATATGTAACTATTGAATATGGGCATG
AAAATAATATATTTATTCCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MVIKLYSIGIPATLNIALPSLLISALNAILAAYSEVYILVLGIYYKLQTFIYLPANGIVQGMRPLIGYNYGAGENKRVSQ
IYKIVLCMSGIIMVLGTVICLLIPGQLMGLFTHTEATIQTGKTALRIIGAGFIVSAVSVTSSGALEGLGKGIPSLLISLC
RYVVVIIPTAFLLSSIFGAVGVWNAFWITEAITAIISICVYYKAISQSQRSQSTVK

Sequences:

>Translated_216_residues
MVIKLYSIGIPATLNIALPSLLISALNAILAAYSEVYILVLGIYYKLQTFIYLPANGIVQGMRPLIGYNYGAGENKRVSQ
IYKIVLCMSGIIMVLGTVICLLIPGQLMGLFTHTEATIQTGKTALRIIGAGFIVSAVSVTSSGALEGLGKGIPSLLISLC
RYVVVIIPTAFLLSSIFGAVGVWNAFWITEAITAIISICVYYKAISQSQRSQSTVK
>Mature_216_residues
MVIKLYSIGIPATLNIALPSLLISALNAILAAYSEVYILVLGIYYKLQTFIYLPANGIVQGMRPLIGYNYGAGENKRVSQ
IYKIVLCMSGIIMVLGTVICLLIPGQLMGLFTHTEATIQTGKTALRIIGAGFIVSAVSVTSSGALEGLGKGIPSLLISLC
RYVVVIIPTAFLLSSIFGAVGVWNAFWITEAITAIISICVYYKAISQSQRSQSTVK

Specific function: Multidrug resistance efflux protein [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 23087; Mature: 23087

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVIKLYSIGIPATLNIALPSLLISALNAILAAYSEVYILVLGIYYKLQTFIYLPANGIVQ
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHH
GMRPLIGYNYGAGENKRVSQIYKIVLCMSGIIMVLGTVICLLIPGQLMGLFTHTEATIQT
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKTALRIIGAGFIVSAVSVTSSGALEGLGKGIPSLLISLCRYVVVIIPTAFLLSSIFGAV
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVWNAFWITEAITAIISICVYYKAISQSQRSQSTVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVIKLYSIGIPATLNIALPSLLISALNAILAAYSEVYILVLGIYYKLQTFIYLPANGIVQ
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHH
GMRPLIGYNYGAGENKRVSQIYKIVLCMSGIIMVLGTVICLLIPGQLMGLFTHTEATIQT
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GKTALRIIGAGFIVSAVSVTSSGALEGLGKGIPSLLISLCRYVVVIIPTAFLLSSIFGAV
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVWNAFWITEAITAIISICVYYKAISQSQRSQSTVK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA