BacMap

Definition	Eubacterium rectale ATCC 33656, complete genome.
Accession	NC_012781
Length	3,449,685

Click here to switch to the map view.

The map label for this gene is ymfI [H]

Identifier: 238925307

GI number: 238925307

Start: 2845751

End: 2846521

Strand: Direct

Name: ymfI [H]

Synonym: EUBREC_2962

Alternate gene names: 238925307

Gene position: 2845751-2846521 (Clockwise)

Preceding gene: 238925298

Following gene: 238925308

Centisome position: 82.49

GC content: 47.99

Gene sequence:

>771_bases
ATGACAAATCAGACAAATCACACCAATCACATAAATCACATAAATAAAACAGCTATAATAACCGGAGCTTCACGCGGTAT
CGGTGCCGCCATTGCCAAAAAGCTGGCTTCCTGTGGCTATAACCTCTCACTTTGCTGCCGCAATTCATCTGACAGGCTAA
AGGCACTGGCTGATGAGCTTCACTGTGCATACGGAATTGAGGTGCTATGCTACACCGGAAATGTAGGAGACTTTTTCTTT
GCCAAGGATATGGTTACGAATACCATTTCCCATTTTGGCCATATAGATGTGCTCATTAACAATGCCGGCATATCGCATAT
CGGGCTACTGAGCGACATGACACCGGAGGAATGGAACAATATCGTGGCGATAAATCTGACCGGTGTTTTCAACTTTACAA
AGCTCGTCACCCCTTATATGGTTGCCGATAAATGTGGCCGCATACTACAGATTTCATCTGTCTGGGGCAATGTCGGAGCC
TCCTGTGAGGTGGCATACTCAGCCTGCAAGGGCGGTATAAATGCATTTACCAAGGCACTCGGCAAGGAGCTTGCGCCATC
GCATATTCCGGTAAATGCCATAGCCTGCGGTGTCATAGATACCGATATGAACCGCTGCTTTGATGAGACAGAACGCGCTG
AGCTGGCCGATGAAATCCCTGCCGGACGCTTTGCCACAGCCTGTGAGGTCGCAGATATGGCTTACTCCGTCATCACTGCA
CCTGATTACCTCACAGGACAGATAATCACTTTTGATGGTGGCTGGATTTAA

Upstream 100 bases:

>100_bases
GTAATTTAATCACGTAATTATTTTCTTTATACTATGAAGCCGGCCCGACAGCGCAGCGATCGGCTTAGCACCACGGTATA
TAAATTATAAGGAGAATATC

Downstream 100 bases:

>100_bases
AATTGTAATTTTAATTTTCGTATTTTTTAGATATTTGTTGATTTTTGTAATTATTGTGTTACAATTCACTTATGAATAGT
ATAAATAACTTTCTATTAGA

Product: 3-oxoacyl-[acyl-carrier-protein] reductase

Products: 3-oxoacyl-[acyl-carrier protein]; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTNQTNHTNHINHINKTAIITGASRGIGAAIAKKLASCGYNLSLCCRNSSDRLKALADELHCAYGIEVLCYTGNVGDFFF
AKDMVTNTISHFGHIDVLINNAGISHIGLLSDMTPEEWNNIVAINLTGVFNFTKLVTPYMVADKCGRILQISSVWGNVGA
SCEVAYSACKGGINAFTKALGKELAPSHIPVNAIACGVIDTDMNRCFDETERAELADEIPAGRFATACEVADMAYSVITA
PDYLTGQIITFDGGWI

Sequences:

>Translated_256_residues
MTNQTNHTNHINHINKTAIITGASRGIGAAIAKKLASCGYNLSLCCRNSSDRLKALADELHCAYGIEVLCYTGNVGDFFF
AKDMVTNTISHFGHIDVLINNAGISHIGLLSDMTPEEWNNIVAINLTGVFNFTKLVTPYMVADKCGRILQISSVWGNVGA
SCEVAYSACKGGINAFTKALGKELAPSHIPVNAIACGVIDTDMNRCFDETERAELADEIPAGRFATACEVADMAYSVITA
PDYLTGQIITFDGGWI
>Mature_255_residues
TNQTNHTNHINHINKTAIITGASRGIGAAIAKKLASCGYNLSLCCRNSSDRLKALADELHCAYGIEVLCYTGNVGDFFFA
KDMVTNTISHFGHIDVLINNAGISHIGLLSDMTPEEWNNIVAINLTGVFNFTKLVTPYMVADKCGRILQISSVWGNVGAS
CEVAYSACKGGINAFTKALGKELAPSHIPVNAIACGVIDTDMNRCFDETERAELADEIPAGRFATACEVADMAYSVITAP
DYLTGQIITFDGGWI

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI40254992, Length=242, Percent_Identity=33.4710743801653, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI19923817, Length=255, Percent_Identity=30.1960784313725, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=30.7692307692308, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI32483357, Length=248, Percent_Identity=28.6290322580645, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI15277342, Length=251, Percent_Identity=28.2868525896414, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI59889578, Length=233, Percent_Identity=29.6137339055794, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI5031737, Length=199, Percent_Identity=26.6331658291457, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI7705925, Length=244, Percent_Identity=25.8196721311475, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=29.6442687747036, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI4503301, Length=235, Percent_Identity=29.3617021276596, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI7706318, Length=168, Percent_Identity=29.1666666666667, Blast_Score=81, Evalue=8e-16,
Organism=Homo sapiens, GI10190704, Length=247, Percent_Identity=27.1255060728745, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI31542939, Length=208, Percent_Identity=29.8076923076923, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=26.4248704663212, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI66933014, Length=182, Percent_Identity=29.1208791208791, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4503817, Length=174, Percent_Identity=29.3103448275862, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI4557649, Length=215, Percent_Identity=28.3720930232558, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI83715985, Length=253, Percent_Identity=28.0632411067194, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=29.8850574712644, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI226371731, Length=208, Percent_Identity=27.4038461538462, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI40254986, Length=250, Percent_Identity=28, Blast_Score=69, Evalue=3e-12,
Organism=Homo sapiens, GI126723191, Length=182, Percent_Identity=29.6703296703297, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI109715829, Length=237, Percent_Identity=25.7383966244726, Blast_Score=65, Evalue=5e-11,
Organism=Escherichia coli, GI1787335, Length=246, Percent_Identity=37.3983739837398, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI87082100, Length=249, Percent_Identity=37.7510040160643, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1790717, Length=244, Percent_Identity=31.1475409836066, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082160, Length=248, Percent_Identity=31.0483870967742, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788459, Length=243, Percent_Identity=30.4526748971193, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=28.5123966942149, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI2367175, Length=246, Percent_Identity=30.8943089430894, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1789057, Length=270, Percent_Identity=26.2962962962963, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786812, Length=255, Percent_Identity=24.7058823529412, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1789378, Length=242, Percent_Identity=24.3801652892562, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=27.1604938271605, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787820, Length=183, Percent_Identity=26.2295081967213, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=30.7692307692308, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=33.0645161290323, Blast_Score=104, Evalue=5e-23,
Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=28.8065843621399, Blast_Score=103, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=32.3886639676113, Blast_Score=102, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17561402, Length=246, Percent_Identity=31.3008130081301, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=29.8449612403101, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17560332, Length=263, Percent_Identity=29.6577946768061, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17555706, Length=246, Percent_Identity=28.8617886178862, Blast_Score=90, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=29.3893129770992, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17536025, Length=248, Percent_Identity=28.2258064516129, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=245, Percent_Identity=27.7551020408163, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17563726, Length=258, Percent_Identity=27.906976744186, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=26.3157894736842, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562908, Length=259, Percent_Identity=28.1853281853282, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=260, Percent_Identity=26.9230769230769, Blast_Score=78, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=26.6409266409266, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17561272, Length=237, Percent_Identity=28.6919831223629, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=187, Percent_Identity=31.0160427807487, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=189, Percent_Identity=31.2169312169312, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17531453, Length=260, Percent_Identity=28.0769230769231, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17538486, Length=268, Percent_Identity=28.3582089552239, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI72000259, Length=257, Percent_Identity=26.0700389105058, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=26.5151515151515, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=258, Percent_Identity=25.5813953488372, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=28.0769230769231, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=256, Percent_Identity=26.5625, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=27.5471698113208, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=266, Percent_Identity=26.6917293233083, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=248, Percent_Identity=26.2096774193548, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17508895, Length=176, Percent_Identity=31.25, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17565030, Length=274, Percent_Identity=27.7372262773723, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=200, Percent_Identity=29, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17570069, Length=197, Percent_Identity=29.9492385786802, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI193203117, Length=169, Percent_Identity=30.7692307692308, Blast_Score=65, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193203115, Length=169, Percent_Identity=30.7692307692308, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17558628, Length=187, Percent_Identity=31.5508021390374, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=189, Percent_Identity=33.8624338624339, Blast_Score=86, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6324126, Length=246, Percent_Identity=26.8292682926829, Blast_Score=76, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6323882, Length=198, Percent_Identity=30.3030303030303, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319635, Length=201, Percent_Identity=28.3582089552239, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI23397609, Length=247, Percent_Identity=35.2226720647773, Blast_Score=120, Evalue=9e-28,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=31.7269076305221, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=33.1983805668016, Blast_Score=109, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21355319, Length=245, Percent_Identity=31.4285714285714, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=30.9803921568627, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24643142, Length=244, Percent_Identity=27.8688524590164, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI24639444, Length=247, Percent_Identity=27.9352226720648, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24640442, Length=205, Percent_Identity=32.1951219512195, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI21358495, Length=193, Percent_Identity=30.5699481865285, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24641232, Length=199, Percent_Identity=29.6482412060301, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI161076933, Length=209, Percent_Identity=28.7081339712919, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24584748, Length=209, Percent_Identity=28.7081339712919, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24584744, Length=211, Percent_Identity=27.9620853080569, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI28574402, Length=211, Percent_Identity=27.9620853080569, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI116007236, Length=199, Percent_Identity=29.6482412060301, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI28571387, Length=246, Percent_Identity=29.6747967479675, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24580925, Length=190, Percent_Identity=31.5789473684211, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI17737361, Length=254, Percent_Identity=25.5905511811024, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21357673, Length=247, Percent_Identity=27.9352226720648, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI18859837, Length=196, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24649181, Length=173, Percent_Identity=29.4797687861272, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100

Molecular weight: Translated: 27448; Mature: 27316

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQTNHTNHINHINKTAIITGASRGIGAAIAKKLASCGYNLSLCCRNSSDRLKALADEL
CCCCCCCCCHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHH
HCAYGIEVLCYTGNVGDFFFAKDMVTNTISHFGHIDVLINNAGISHIGLLSDMTPEEWNN
HHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCCHHHHCC
IVAINLTGVFNFTKLVTPYMVADKCGRILQISSVWGNVGASCEVAYSACKGGINAFTKAL
EEEEEEECHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCCHHHHHHHHHCCHHHHHHHH
GKELAPSHIPVNAIACGVIDTDMNRCFDETERAELADEIPAGRFATACEVADMAYSVITA
HHHCCCCCCCHHHEEEEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
PDYLTGQIITFDGGWI
CCCCCCEEEEECCCCC
>Mature Secondary Structure 
TNQTNHTNHINHINKTAIITGASRGIGAAIAKKLASCGYNLSLCCRNSSDRLKALADEL
CCCCCCCCHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHH
HCAYGIEVLCYTGNVGDFFFAKDMVTNTISHFGHIDVLINNAGISHIGLLSDMTPEEWNN
HHHCCCEEEEEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCCHHHHCC
IVAINLTGVFNFTKLVTPYMVADKCGRILQISSVWGNVGASCEVAYSACKGGINAFTKAL
EEEEEEECHHHHHHHHHHHHHHHHCCCEEEEEHHHCCCCCCHHHHHHHHHCCHHHHHHHH
GKELAPSHIPVNAIACGVIDTDMNRCFDETERAELADEIPAGRFATACEVADMAYSVITA
HHHCCCCCCCHHHEEEEEEECHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
PDYLTGQIITFDGGWI
CCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (3R)-3-hydroxyacyl-[acyl-carrier protein]; NADP+

Specific reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]