| Definition | Eubacterium rectale ATCC 33656, complete genome. |
|---|---|
| Accession | NC_012781 |
| Length | 3,449,685 |
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The map label for this gene is capD [H]
Identifier: 238924968
GI number: 238924968
Start: 2496210
End: 2498291
Strand: Reverse
Name: capD [H]
Synonym: EUBREC_2619
Alternate gene names: 238924968
Gene position: 2498291-2496210 (Counterclockwise)
Preceding gene: 238924969
Following gene: 238924967
Centisome position: 72.42
GC content: 44.28
Gene sequence:
>2082_bases TTGTTTGAATTATATTTTAATATATTTTATGAGAAGTTGATTTATAAGGGCGATAAAAGCTGTAAATATTTTGCAGTGTG GGGTAAAAGGAGAAAGTCCTATATGAAAAATAAGAATTTTAACATAAATAGTAACACTAATGATGGCAGTAAAGTCAACG ATAACAACACTAATCATAAAGGTGTAACAAAATATGACGGCCCTGAAAAACCTGATGCTTATATGGGAAATGACAGACAG TGGGTTGTGAGAGCTTTTTTGCTGGCATTTATAGATGTATGTATTATGGCGGTGTCATTTTTCTTTGCTTTAATGATAAG ATTTGAGTTCGCGTATTCACATATTCCGGATTTATATCTTGCAGGTTATATAAAGATAGTGCCTGTTTTTGTGGCAATTG CTTTGGCTGTGTTTTATATTTTCAGGCTGTACCACAGTATATGGCGCTTTGCGAGCATCAACGAGTTTATGCATATTATT GGTGCCTTTCTGGTGCTTGCGGTTGTGAGCGTTACTATTCATGAGGTGTATGAGATTAAGATGCCGTATGCTTTCTGGAT TATCGGACTGATGCTCAGCTTTGCACTTTGTACAGCATGCCGTTTTGCGTACAGATTTATCAGGACAGGTCAGAAGATGC TTGAGCAGAGAGGCTCCGCAAACGGTGATGAGAAGGTCATGATTATAGGAGCCGGAAATGCGGGAAGGATGCTTATCAGG GAGCTTATCATGAGCTCACATCTGCACACAAAGGCCTGCTGCATCATAGATGACAATCCGGCGAAGCTGGGGCGCTTTAT AGATGGCGTGCCTATTGTCGGCAACAGAAATGACATTCCAGAGATGGTTGAGAAGTATGATATCACGAAAATTGTGTATG CTGTACCTTCTACATCCGGTAAGGACAGGAAGGATATACTCAATATTTGTAAGGATACCGGCTGTGATGTGTCTGTGGTT CCGGGAATCTATCAGATGGTGGACGGAAGAGTGTCGGTTTCCAATCTGCGTCCGGTAAGCATTGAGGATTTGCTGGGCAG AGATCCGGTTGTTGTGGATAATGACGGTATTCATTCATTTTTACAGGGCAAGGTGGTCATGGTTACAGGTGGCGGTGGCT CAATAGGTAGTGAGCTTTGCCGTCAGATAGCCAGGGAGGATCCGAAGCTTCTTATCATTTTTGATATTTACGAGAATAAT GCATACGATATACAGCAGGAGCTGAAGCGCAAATATCCTTATGTAAGGGTGGAGACGCTGATTGGCTCGGTGCGCAATAC TAACAGGCTGCACTATGTATTCCAGACATATCATCCGGAGATTATTTATCATGCGGCAGCACATAAGCATGTACCGCTGA TGGAGGAAAGCCCGAATGAGGCAATAAAGAACAATGTGCTTGGCACATTAAAGCTCTCAAGGATTGCAGCAGAGTACCAT GTGAAGAAGTTCGTGCTTATATCTACGGATAAGGCGGTTAATCCAACCAATATCATGGGTGCATCAAAGCGTCTGTGTGA GATGGTTATACAGATGATGAACAGGCAGACTGAGACTGATTTTGTCGCTGTGCGTTTTGGAAACGTGCTTGGCAGCAATG GTAGTGTTATCCCGCTGTTTAAGAAGCAGATAGAGGATGGCGGTCCTGTTACTGTGACGGACAAGCGTATTATCAGGTAT TTTATGACAATTCCGGAGGCTGTGGCGCTTGTGCTGCAGGCAGGGCTCTATGCTCACGGAGGCGAGATTTTCGTGCTCGA CATGGGCGAGCCGGTCAAGATTGATGATATGGCTAGGAACCTTATCAGGCTTTCAGGACTGGAGCCGGATGTGGATATTC AGATTGTATACACAGGCCTGCGTCCGGGCGAGAAGCTCTACGAGGAGATGCTGATGAGCGAGGAGGGTCTCAAGGAGACT CCGAACAAGCTGATTCATGTGGGTGAGCCTATTGAGATGGATGATGAGCTCTTTGAGAAGCAGCTTGAGATGCTCGAGAA GGCATGCACCTCAGAAGCAAAGGATATCAAGCAGATAGTGGCCTCTGTGGTAAAGACATATCATCCTGACCTGGAAAACT AA
Upstream 100 bases:
>100_bases GATAAGCAAGCTGTTTGTATTTAAGAATCATTAGAATATGAATATTTAATAAAATAATAAGAACTATAATTAATGTGGTA TGATATAATGAATATATATT
Downstream 100 bases:
>100_bases ATATCTTTTGAAGTGCATAATATAGACTGTAAAAGCCGGATGTTTGGCATATTTTATGCCGGAAGCGAGGAACATAACTA TGGAAAAGAGACAGATTTCA
Product: UDP-N-acetylglucosamine 4,6-dehydratase / UDP-D-quinovosamine 4-dehydrogenase
Products: UDPglucoseal [C]
Alternate protein names: NA
Number of amino acids: Translated: 693; Mature: 693
Protein sequence:
>693_residues MFELYFNIFYEKLIYKGDKSCKYFAVWGKRRKSYMKNKNFNINSNTNDGSKVNDNNTNHKGVTKYDGPEKPDAYMGNDRQ WVVRAFLLAFIDVCIMAVSFFFALMIRFEFAYSHIPDLYLAGYIKIVPVFVAIALAVFYIFRLYHSIWRFASINEFMHII GAFLVLAVVSVTIHEVYEIKMPYAFWIIGLMLSFALCTACRFAYRFIRTGQKMLEQRGSANGDEKVMIIGAGNAGRMLIR ELIMSSHLHTKACCIIDDNPAKLGRFIDGVPIVGNRNDIPEMVEKYDITKIVYAVPSTSGKDRKDILNICKDTGCDVSVV PGIYQMVDGRVSVSNLRPVSIEDLLGRDPVVVDNDGIHSFLQGKVVMVTGGGGSIGSELCRQIAREDPKLLIIFDIYENN AYDIQQELKRKYPYVRVETLIGSVRNTNRLHYVFQTYHPEIIYHAAAHKHVPLMEESPNEAIKNNVLGTLKLSRIAAEYH VKKFVLISTDKAVNPTNIMGASKRLCEMVIQMMNRQTETDFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTDKRIIRY FMTIPEAVALVLQAGLYAHGGEIFVLDMGEPVKIDDMARNLIRLSGLEPDVDIQIVYTGLRPGEKLYEEMLMSEEGLKET PNKLIHVGEPIEMDDELFEKQLEMLEKACTSEAKDIKQIVASVVKTYHPDLEN
Sequences:
>Translated_693_residues MFELYFNIFYEKLIYKGDKSCKYFAVWGKRRKSYMKNKNFNINSNTNDGSKVNDNNTNHKGVTKYDGPEKPDAYMGNDRQ WVVRAFLLAFIDVCIMAVSFFFALMIRFEFAYSHIPDLYLAGYIKIVPVFVAIALAVFYIFRLYHSIWRFASINEFMHII GAFLVLAVVSVTIHEVYEIKMPYAFWIIGLMLSFALCTACRFAYRFIRTGQKMLEQRGSANGDEKVMIIGAGNAGRMLIR ELIMSSHLHTKACCIIDDNPAKLGRFIDGVPIVGNRNDIPEMVEKYDITKIVYAVPSTSGKDRKDILNICKDTGCDVSVV PGIYQMVDGRVSVSNLRPVSIEDLLGRDPVVVDNDGIHSFLQGKVVMVTGGGGSIGSELCRQIAREDPKLLIIFDIYENN AYDIQQELKRKYPYVRVETLIGSVRNTNRLHYVFQTYHPEIIYHAAAHKHVPLMEESPNEAIKNNVLGTLKLSRIAAEYH VKKFVLISTDKAVNPTNIMGASKRLCEMVIQMMNRQTETDFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTDKRIIRY FMTIPEAVALVLQAGLYAHGGEIFVLDMGEPVKIDDMARNLIRLSGLEPDVDIQIVYTGLRPGEKLYEEMLMSEEGLKET PNKLIHVGEPIEMDDELFEKQLEMLEKACTSEAKDIKQIVASVVKTYHPDLEN >Mature_693_residues MFELYFNIFYEKLIYKGDKSCKYFAVWGKRRKSYMKNKNFNINSNTNDGSKVNDNNTNHKGVTKYDGPEKPDAYMGNDRQ WVVRAFLLAFIDVCIMAVSFFFALMIRFEFAYSHIPDLYLAGYIKIVPVFVAIALAVFYIFRLYHSIWRFASINEFMHII GAFLVLAVVSVTIHEVYEIKMPYAFWIIGLMLSFALCTACRFAYRFIRTGQKMLEQRGSANGDEKVMIIGAGNAGRMLIR ELIMSSHLHTKACCIIDDNPAKLGRFIDGVPIVGNRNDIPEMVEKYDITKIVYAVPSTSGKDRKDILNICKDTGCDVSVV PGIYQMVDGRVSVSNLRPVSIEDLLGRDPVVVDNDGIHSFLQGKVVMVTGGGGSIGSELCRQIAREDPKLLIIFDIYENN AYDIQQELKRKYPYVRVETLIGSVRNTNRLHYVFQTYHPEIIYHAAAHKHVPLMEESPNEAIKNNVLGTLKLSRIAAEYH VKKFVLISTDKAVNPTNIMGASKRLCEMVIQMMNRQTETDFVAVRFGNVLGSNGSVIPLFKKQIEDGGPVTVTDKRIIRY FMTIPEAVALVLQAGLYAHGGEIFVLDMGEPVKIDDMARNLIRLSGLEPDVDIQIVYTGLRPGEKLYEEMLMSEEGLKET PNKLIHVGEPIEMDDELFEKQLEMLEKACTSEAKDIKQIVASVVKTYHPDLEN
Specific function: Required for the biosynthesis of type 1 capsular polysaccharide [H]
COG id: COG1086
COG function: function code MG; Predicted nucleoside-diphosphate sugar epimerases
Gene ontology:
Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the polysaccharide synthase family [H]
Homologues:
Organism=Homo sapiens, GI7657641, Length=288, Percent_Identity=26.3888888888889, Blast_Score=69, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR016040 - InterPro: IPR003869 [H]
Pfam domain/function: PF02719 Polysacc_synt_2 [H]
EC number: 5.1.3.2 [C]
Molecular weight: Translated: 78483; Mature: 78483
Theoretical pI: Translated: 7.10; Mature: 7.10
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 3.9 %Met (Translated Protein) 5.5 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 3.9 %Met (Mature Protein) 5.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MFELYFNIFYEKLIYKGDKSCKYFAVWGKRRKSYMKNKNFNINSNTNDGSKVNDNNTNHK CEEHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC GVTKYDGPEKPDAYMGNDRQWVVRAFLLAFIDVCIMAVSFFFALMIRFEFAYSHIPDLYL CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH AGYIKIVPVFVAIALAVFYIFRLYHSIWRFASINEFMHIIGAFLVLAVVSVTIHEVYEIK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC MPYAFWIIGLMLSFALCTACRFAYRFIRTGQKMLEQRGSANGDEKVMIIGAGNAGRMLIR CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHH ELIMSSHLHTKACCIIDDNPAKLGRFIDGVPIVGNRNDIPEMVEKYDITKIVYAVPSTSG HHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCHHEEEEECCCCCC KDRKDILNICKDTGCDVSVVPGIYQMVDGRVSVSNLRPVSIEDLLGRDPVVVDNDGIHSF CCHHHHHHHHHCCCCCEEECCHHHHHHCCCEEECCCCCCCHHHHCCCCCEEECCCCHHHH LQGKVVMVTGGGGSIGSELCRQIAREDPKLLIIFDIYENNAYDIQQELKRKYPYVRVETL HCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCEEHHHH IGSVRNTNRLHYVFQTYHPEIIYHAAAHKHVPLMEESPNEAIKNNVLGTLKLSRIAAEYH HHHHCCCCCEEEEEEECCCHHEEEHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHH VKKFVLISTDKAVNPTNIMGASKRLCEMVIQMMNRQTETDFVAVRFGNVLGSNGSVIPLF HEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHCCCCCCEEHHH KKQIEDGGPVTVTDKRIIRYFMTIPEAVALVLQAGLYAHGGEIFVLDMGEPVKIDDMARN HHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEEECCCCCCHHHHHHH LIRLSGLEPDVDIQIVYTGLRPGEKLYEEMLMSEEGLKETPNKLIHVGEPIEMDDELFEK HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHEEECCCCCCCCHHHHHH QLEMLEKACTSEAKDIKQIVASVVKTYHPDLEN HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC >Mature Secondary Structure MFELYFNIFYEKLIYKGDKSCKYFAVWGKRRKSYMKNKNFNINSNTNDGSKVNDNNTNHK CEEHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC GVTKYDGPEKPDAYMGNDRQWVVRAFLLAFIDVCIMAVSFFFALMIRFEFAYSHIPDLYL CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH AGYIKIVPVFVAIALAVFYIFRLYHSIWRFASINEFMHIIGAFLVLAVVSVTIHEVYEIK HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC MPYAFWIIGLMLSFALCTACRFAYRFIRTGQKMLEQRGSANGDEKVMIIGAGNAGRMLIR CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHHHH ELIMSSHLHTKACCIIDDNPAKLGRFIDGVPIVGNRNDIPEMVEKYDITKIVYAVPSTSG HHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCHHEEEEECCCCCC KDRKDILNICKDTGCDVSVVPGIYQMVDGRVSVSNLRPVSIEDLLGRDPVVVDNDGIHSF CCHHHHHHHHHCCCCCEEECCHHHHHHCCCEEECCCCCCCHHHHCCCCCEEECCCCHHHH LQGKVVMVTGGGGSIGSELCRQIAREDPKLLIIFDIYENNAYDIQQELKRKYPYVRVETL HCCCEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHCCCEEHHHH IGSVRNTNRLHYVFQTYHPEIIYHAAAHKHVPLMEESPNEAIKNNVLGTLKLSRIAAEYH HHHHCCCCCEEEEEEECCCHHEEEHHHCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHH VKKFVLISTDKAVNPTNIMGASKRLCEMVIQMMNRQTETDFVAVRFGNVLGSNGSVIPLF HEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECHHCCCCCCEEHHH KKQIEDGGPVTVTDKRIIRYFMTIPEAVALVLQAGLYAHGGEIFVLDMGEPVKIDDMARN HHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCEECCCEEEEEECCCCCCHHHHHHH LIRLSGLEPDVDIQIVYTGLRPGEKLYEEMLMSEEGLKETPNKLIHVGEPIEMDDELFEK HHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHEEECCCCCCCCHHHHHH QLEMLEKACTSEAKDIKQIVASVVKTYHPDLEN HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NAD+ [C]
Metal ions: NA
Kcat value (1/min): 57600 [C]
Specific activity: 233.3
Km value (mM): 0.256 {UDPgalactose}} 0.225 {UDPgalactose}} 0.2 {UDPgalactose}} 0.18 {UDPgalactose}} 0.16 {UDPgalactose}} 0.14 {UDPgalactose}} 0.048 {UDPgalactose}} 0.026 {UDPgalactose}} [C]
Substrates: UDPglucose [C]
Specific reaction: UDPglucose <==> UDPglucoseal [C]
General reaction: Epimerization (specificity for carbon forming a hexosulose) [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: 7961465 [H]