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The map label for this gene is yyxA [H]

Identifier: 238924959

GI number: 238924959

Start: 2487081

End: 2488676

Strand: Reverse

Name: yyxA [H]

Synonym: EUBREC_2610

Alternate gene names: 238924959

Gene position: 2488676-2487081 (Counterclockwise)

Preceding gene: 238924960

Following gene: 238924958

Centisome position: 72.14

GC content: 42.67

Gene sequence:

>1596_bases
ATGGATAACAATTATAGAAATATGAATGATACAAATAATACTAACAGTACAAATAACACAAATAACAATACAAATAATGT
AAATTTCACAATGTCGGGTAATCCTTACAATCCGGATGAGTCACAGAAGGCTGCACAGACTAATAATACATCAGCTGAAA
GCTATTCACAGAGCTACAATCCATATTCGCAGGCTTCTACAGCAGGACAGCCAAATGCAAATCAGTCATATGCAAACCAG
CCTTATTCTAATCAGTCGTATAATTCAGGCACAAATAATAATGCATATTGCGGCACATCAGCAGGTTCGACAGACAATTC
ATATAGCAGGATGAATATGAATGGTCAGGCATACCAGCAGACTGCAAAGCCTAAGAAACAGAGAGCACCTAGAAAGCCTG
GTGCATTTGGACCATTTGCAGCAAAGACAGTAGCGGCAGCTCTTATCTTCGGACTCGTCGGAGGCGGCGTTTTCACAGGA
GTAAGCTATATTGGCACGAGAGCTATTTCAAATTCTTCTACTGCAAGTGCAAAGCTTACCACTACAACATCTGGTGGGAC
TAAGCAGACATCCTCAGGGAATGCAAAGGATCTGACAGATGTATCATCAGTTGTCGATGAGGTAATGCCTAGCATCGTTG
CTATCACAAATACAGGAACAGTCACCTACAACAGCTTTTTCGGAAAGCAGTCACAGCAGTCTCAGAGCTGTGGCTCAGGT
ATTATTGTGAGTGAGGATGATGATTATCTCTACATTGCTACAAACAATCATGTTGTGGCAGATTCAGAGGAGCTCACAGT
ACAGTTTGATGATGATTCAGTGGTAAAGGCAGAAATCAGAGGAACAGATCCGGATGACGATCTAGCAGTTGTACGTGTAA
AGAAAGCAGACCTTGGAAAAGATACTTACTCAAATATCAAGATTGCTACAATCGGAGATTCTGAAAGTGTAGCTGTTGGA
AGTCCTGCAATTGCTATCGGTAATGCACTTGGATACGGACAGTCTGTCACAACAGGTATAGTAAGTGCGCTTAACAGAAC
CGTAACTACACAGGATTCACAGACAGGTGAGACTGTTACCAACAACAAGCTTATTCAGACGGATGCAGCCATAAACCCTG
GAAACAGTGGTGGAGCACTCTTGAATGAAAATGGCGAGGTTATCGGTATAAACTCTGTAAAATATTCTTCAACTGAAGTT
GAGGGTATCGGATATGCAATTCCTATGTCGGTTGCAAAGCCTATTATTGAGAGCCTTATCCAGGATGGAAAATATACTAA
TGAGAATCAGGCATACCTTGGTATCAAGGGTGGCGATGTTTCATCTGAGATGGTAGCCTATGGCTTCCCACAGGGTGTGT
ATGTTTCATCTGTTTCAGCTGGTTCAGGTGCCGCAAATGCCGGCTTACAGGAGGGAGATATCATCACTGCTGTTGACAGC
ACAAAGATTTCTTCTATGACAGAGCTGCAGTCAGCGTTAAAGAGCTACAAGGCCGGAGATAAGGTTACTCTTACTGTTGC
CCGTCAGAGTGGCAGACAGTACGAAGAGAACAAGGTTGAAGTAACCTTAAGCTCTGCAAAGGATATTCAGCAGTAA

Upstream 100 bases:

>100_bases
AGCACGGGGATTACAATTTATGAAAAAATAAATAATCCCGTCACAAATTAAACACAGATTGACAGTATACTTCTAATTGT
AAACGAAAGGAGAAATTATT

Downstream 100 bases:

>100_bases
ATAATTCATTTATATTTATGAGTACAAAAACGCGCCAGTGTGGCGCGTTTTTTGTTATGAAAAATATAGTTAAGGGTTGA
TTTTTTAAATAAAAAGGTGT

Product: 2-alkenal reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 531

Protein sequence:

>531_residues
MDNNYRNMNDTNNTNSTNNTNNNTNNVNFTMSGNPYNPDESQKAAQTNNTSAESYSQSYNPYSQASTAGQPNANQSYANQ
PYSNQSYNSGTNNNAYCGTSAGSTDNSYSRMNMNGQAYQQTAKPKKQRAPRKPGAFGPFAAKTVAAALIFGLVGGGVFTG
VSYIGTRAISNSSTASAKLTTTTSGGTKQTSSGNAKDLTDVSSVVDEVMPSIVAITNTGTVTYNSFFGKQSQQSQSCGSG
IIVSEDDDYLYIATNNHVVADSEELTVQFDDDSVVKAEIRGTDPDDDLAVVRVKKADLGKDTYSNIKIATIGDSESVAVG
SPAIAIGNALGYGQSVTTGIVSALNRTVTTQDSQTGETVTNNKLIQTDAAINPGNSGGALLNENGEVIGINSVKYSSTEV
EGIGYAIPMSVAKPIIESLIQDGKYTNENQAYLGIKGGDVSSEMVAYGFPQGVYVSSVSAGSGAANAGLQEGDIITAVDS
TKISSMTELQSALKSYKAGDKVTLTVARQSGRQYEENKVEVTLSSAKDIQQ

Sequences:

>Translated_531_residues
MDNNYRNMNDTNNTNSTNNTNNNTNNVNFTMSGNPYNPDESQKAAQTNNTSAESYSQSYNPYSQASTAGQPNANQSYANQ
PYSNQSYNSGTNNNAYCGTSAGSTDNSYSRMNMNGQAYQQTAKPKKQRAPRKPGAFGPFAAKTVAAALIFGLVGGGVFTG
VSYIGTRAISNSSTASAKLTTTTSGGTKQTSSGNAKDLTDVSSVVDEVMPSIVAITNTGTVTYNSFFGKQSQQSQSCGSG
IIVSEDDDYLYIATNNHVVADSEELTVQFDDDSVVKAEIRGTDPDDDLAVVRVKKADLGKDTYSNIKIATIGDSESVAVG
SPAIAIGNALGYGQSVTTGIVSALNRTVTTQDSQTGETVTNNKLIQTDAAINPGNSGGALLNENGEVIGINSVKYSSTEV
EGIGYAIPMSVAKPIIESLIQDGKYTNENQAYLGIKGGDVSSEMVAYGFPQGVYVSSVSAGSGAANAGLQEGDIITAVDS
TKISSMTELQSALKSYKAGDKVTLTVARQSGRQYEENKVEVTLSSAKDIQQ
>Mature_531_residues
MDNNYRNMNDTNNTNSTNNTNNNTNNVNFTMSGNPYNPDESQKAAQTNNTSAESYSQSYNPYSQASTAGQPNANQSYANQ
PYSNQSYNSGTNNNAYCGTSAGSTDNSYSRMNMNGQAYQQTAKPKKQRAPRKPGAFGPFAAKTVAAALIFGLVGGGVFTG
VSYIGTRAISNSSTASAKLTTTTSGGTKQTSSGNAKDLTDVSSVVDEVMPSIVAITNTGTVTYNSFFGKQSQQSQSCGSG
IIVSEDDDYLYIATNNHVVADSEELTVQFDDDSVVKAEIRGTDPDDDLAVVRVKKADLGKDTYSNIKIATIGDSESVAVG
SPAIAIGNALGYGQSVTTGIVSALNRTVTTQDSQTGETVTNNKLIQTDAAINPGNSGGALLNENGEVIGINSVKYSSTEV
EGIGYAIPMSVAKPIIESLIQDGKYTNENQAYLGIKGGDVSSEMVAYGFPQGVYVSSVSAGSGAANAGLQEGDIITAVDS
TKISSMTELQSALKSYKAGDKVTLTVARQSGRQYEENKVEVTLSSAKDIQQ

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=344, Percent_Identity=30.2325581395349, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI24308541, Length=321, Percent_Identity=28.3489096573209, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI4506141, Length=307, Percent_Identity=29.6416938110749, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI7019477, Length=311, Percent_Identity=29.5819935691318, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI1789629, Length=344, Percent_Identity=35.4651162790698, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI1786356, Length=368, Percent_Identity=33.695652173913, Blast_Score=170, Evalue=2e-43,
Organism=Escherichia coli, GI1789630, Length=313, Percent_Identity=32.5878594249201, Blast_Score=137, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24646839, Length=400, Percent_Identity=27.75, Blast_Score=114, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 55636; Mature: 55636

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNNYRNMNDTNNTNSTNNTNNNTNNVNFTMSGNPYNPDESQKAAQTNNTSAESYSQSYN
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHCCC
PYSQASTAGQPNANQSYANQPYSNQSYNSGTNNNAYCGTSAGSTDNSYSRMNMNGQAYQQ
CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEECCCCHHHHH
TAKPKKQRAPRKPGAFGPFAAKTVAAALIFGLVGGGVFTGVSYIGTRAISNSSTASAKLT
HCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEE
TTTSGGTKQTSSGNAKDLTDVSSVVDEVMPSIVAITNTGTVTYNSFFGKQSQQSQSCGSG
EECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCEEEEHHHCCCCCHHHHHCCCC
IIVSEDDDYLYIATNNHVVADSEELTVQFDDDSVVKAEIRGTDPDDDLAVVRVKKADLGK
EEEECCCCEEEEEECCEEEECCCEEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCCCC
DTYSNIKIATIGDSESVAVGSPAIAIGNALGYGQSVTTGIVSALNRTVTTQDSQTGETVT
CCCCCEEEEEECCCCCEEECCCCEEECCHHCCCCHHHHHHHHHHHCCEECCCCCCCCEEC
NNKLIQTDAAINPGNSGGALLNENGEVIGINSVKYSSTEVEGIGYAIPMSVAKPIIESLI
CCEEEEECCCCCCCCCCCEEECCCCCEEEECCEEECCCCCCCCCEECCHHHHHHHHHHHH
QDGKYTNENQAYLGIKGGDVSSEMVAYGFPQGVYVSSVSAGSGAANAGLQEGDIITAVDS
HCCCCCCCCCEEEEEECCCCCCCHHEECCCCCEEEEEECCCCCCCCCCCCCCCEEEEECC
TKISSMTELQSALKSYKAGDKVTLTVARQSGRQYEENKVEVTLSSAKDIQQ
CHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEEECCCCCCCC
>Mature Secondary Structure
MDNNYRNMNDTNNTNSTNNTNNNTNNVNFTMSGNPYNPDESQKAAQTNNTSAESYSQSYN
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCHHHHHHHCCCCCHHHHHHCCC
PYSQASTAGQPNANQSYANQPYSNQSYNSGTNNNAYCGTSAGSTDNSYSRMNMNGQAYQQ
CHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCEEECCCCHHHHH
TAKPKKQRAPRKPGAFGPFAAKTVAAALIFGLVGGGVFTGVSYIGTRAISNSSTASAKLT
HCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCEEEE
TTTSGGTKQTSSGNAKDLTDVSSVVDEVMPSIVAITNTGTVTYNSFFGKQSQQSQSCGSG
EECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCEEEEHHHCCCCCHHHHHCCCC
IIVSEDDDYLYIATNNHVVADSEELTVQFDDDSVVKAEIRGTDPDDDLAVVRVKKADLGK
EEEECCCCEEEEEECCEEEECCCEEEEEECCCCEEEEEECCCCCCCCEEEEEEECCCCCC
DTYSNIKIATIGDSESVAVGSPAIAIGNALGYGQSVTTGIVSALNRTVTTQDSQTGETVT
CCCCCEEEEEECCCCCEEECCCCEEECCHHCCCCHHHHHHHHHHHCCEECCCCCCCCEEC
NNKLIQTDAAINPGNSGGALLNENGEVIGINSVKYSSTEVEGIGYAIPMSVAKPIIESLI
CCEEEEECCCCCCCCCCCEEECCCCCEEEECCEEECCCCCCCCCEECCHHHHHHHHHHHH
QDGKYTNENQAYLGIKGGDVSSEMVAYGFPQGVYVSSVSAGSGAANAGLQEGDIITAVDS
HCCCCCCCCCEEEEEECCCCCCCHHEECCCCCEEEEEECCCCCCCCCCCCCCCEEEEECC
TKISSMTELQSALKSYKAGDKVTLTVARQSGRQYEENKVEVTLSSAKDIQQ
CHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8113162 [H]