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The map label for this gene is dapB [H]

Identifier: 238924883

GI number: 238924883

Start: 2406731

End: 2407492

Strand: Reverse

Name: dapB [H]

Synonym: EUBREC_2534

Alternate gene names: 238924883

Gene position: 2407492-2406731 (Counterclockwise)

Preceding gene: 238924884

Following gene: 238924881

Centisome position: 69.79

GC content: 46.06

Gene sequence:

>762_bases
ATGACAAAGGTAATTATGAATGGCTGCAACGGCAAAATGGGACAGACTATCACAGAAATCTGTAAGGCTGATGCGGATAT
CGAGATTGTAGCCGGTATTGATTTATATGATGGAATAGACAATGACTATCCTGTTTTTTCGAGCATTGACAAATGTGATG
TGGACGCTGATGTGGTCATAGATTTTTCCAATGCCAAGGCTGTTGACGGAGTGCTGGACTATTGTGTGGACAAGCAGGTT
CCGGTTGTTTTATGCACTACCGGTCTTAGTGATGAGCAGCTTGCAAAGGTTGAGGAGTGCTACAAGAAGGTGGCAGTGCT
CAAGTCTGCAAACATGTCACTTGGCATAAACACTCTTATGGCTCTTCTCAAAAAGGCTGCACAGGTTTTCGCACCGGCAG
GTTTTGACATGGAGATAGTTGAGAAGCATCACAATTTAAAGCTTGATGCACCTTCAGGTACTGCGCTTGCGCTTGCTGAT
TCCATCAACGAGGCTATGGATAACGAGTATCACTATGTTTACGACCGCAGCCAGCGCAGAGAGAAGCGTGATCCTAAGGA
AATTGGTATTTCTGCTGTCAGAGGAGGAAGCATCGTCGGTGAGCACGAGGTACTTTTCTGTGGACAGGATGAGGTGATTG
AGTTTAAGCATACTGCTTACTCTAAGGCTGTTTTTGCGAAGGGGGCTGTTGAGGCTGCCAAGTTCCTTAAGGGAAAGGGT
GCAGGTCACTACGATATGGCGGATGTTATTGCAGCTAAGTAG

Upstream 100 bases:

>100_bases
TATGTGCGAGATGGGTGAGGATAACGCAAGGAAGCTTGCTGAGGTCATGAAGGCTTATGGCTTAAAGCTTGCTTAGTACA
ACGAGAAAGGATACGATAAA

Downstream 100 bases:

>100_bases
ATTTAGGCTGTTTATCATTGTGGCGATAGGTCGGGCGTAGGCTCCGGGCAACAGGGGGGCACACGCACTCTCCCGGGGCG
CTACGCTACGTGGCTAAGAT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR [H]

Number of amino acids: Translated: 253; Mature: 252

Protein sequence:

>253_residues
MTKVIMNGCNGKMGQTITEICKADADIEIVAGIDLYDGIDNDYPVFSSIDKCDVDADVVIDFSNAKAVDGVLDYCVDKQV
PVVLCTTGLSDEQLAKVEECYKKVAVLKSANMSLGINTLMALLKKAAQVFAPAGFDMEIVEKHHNLKLDAPSGTALALAD
SINEAMDNEYHYVYDRSQRREKRDPKEIGISAVRGGSIVGEHEVLFCGQDEVIEFKHTAYSKAVFAKGAVEAAKFLKGKG
AGHYDMADVIAAK

Sequences:

>Translated_253_residues
MTKVIMNGCNGKMGQTITEICKADADIEIVAGIDLYDGIDNDYPVFSSIDKCDVDADVVIDFSNAKAVDGVLDYCVDKQV
PVVLCTTGLSDEQLAKVEECYKKVAVLKSANMSLGINTLMALLKKAAQVFAPAGFDMEIVEKHHNLKLDAPSGTALALAD
SINEAMDNEYHYVYDRSQRREKRDPKEIGISAVRGGSIVGEHEVLFCGQDEVIEFKHTAYSKAVFAKGAVEAAKFLKGKG
AGHYDMADVIAAK
>Mature_252_residues
TKVIMNGCNGKMGQTITEICKADADIEIVAGIDLYDGIDNDYPVFSSIDKCDVDADVVIDFSNAKAVDGVLDYCVDKQVP
VVLCTTGLSDEQLAKVEECYKKVAVLKSANMSLGINTLMALLKKAAQVFAPAGFDMEIVEKHHNLKLDAPSGTALALADS
INEAMDNEYHYVYDRSQRREKRDPKEIGISAVRGGSIVGEHEVLFCGQDEVIEFKHTAYSKAVFAKGAVEAAKFLKGKGA
GHYDMADVIAAK

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786214, Length=263, Percent_Identity=34.2205323193916, Blast_Score=142, Evalue=2e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040 [H]

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N [H]

EC number: =1.3.1.26 [H]

Molecular weight: Translated: 27380; Mature: 27248

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKVIMNGCNGKMGQTITEICKADADIEIVAGIDLYDGIDNDYPVFSSIDKCDVDADVVI
CCEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCHHCCCCCCCCHHCCCCCCCCCCEEEE
DFSNAKAVDGVLDYCVDKQVPVVLCTTGLSDEQLAKVEECYKKVAVLKSANMSLGINTLM
EECCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
ALLKKAAQVFAPAGFDMEIVEKHHNLKLDAPSGTALALADSINEAMDNEYHYVYDRSQRR
HHHHHHHHHHCCCCCCHHHHHHCCCEEEECCCCCEEHHHHHHHHHHCCCEEEEECCHHHH
EKRDPKEIGISAVRGGSIVGEHEVLFCGQDEVIEFKHTAYSKAVFAKGAVEAAKFLKGKG
HHCCHHHHCCCCCCCCCEECCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
AGHYDMADVIAAK
CCCCCHHHHHHCC
>Mature Secondary Structure 
TKVIMNGCNGKMGQTITEICKADADIEIVAGIDLYDGIDNDYPVFSSIDKCDVDADVVI
CEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCHHCCCCCCCCHHCCCCCCCCCCEEEE
DFSNAKAVDGVLDYCVDKQVPVVLCTTGLSDEQLAKVEECYKKVAVLKSANMSLGINTLM
EECCCHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
ALLKKAAQVFAPAGFDMEIVEKHHNLKLDAPSGTALALADSINEAMDNEYHYVYDRSQRR
HHHHHHHHHHCCCCCCHHHHHHCCCEEEECCCCCEEHHHHHHHHHHCCCEEEEECCHHHH
EKRDPKEIGISAVRGGSIVGEHEVLFCGQDEVIEFKHTAYSKAVFAKGAVEAAKFLKGKG
HHCCHHHHCCCCCCCCCEECCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
AGHYDMADVIAAK
CCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]