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The map label for this gene is dapA [H]

Identifier: 238924884

GI number: 238924884

Start: 2407517

End: 2408407

Strand: Reverse

Name: dapA [H]

Synonym: EUBREC_2535

Alternate gene names: 238924884

Gene position: 2408407-2407517 (Counterclockwise)

Preceding gene: 238924885

Following gene: 238924883

Centisome position: 69.82

GC content: 47.25

Gene sequence:

>891_bases
ATGGCAATTTTCAAAGGAGCAGGAGTAGCAATTGTTACACCTATGTACGATAACGAGGAGGTTAATTACGACAAGCTCGA
GGAGCTTATCAATATGCAGATTGATAATGGCACAGATGCTATTATCATTGCCGGCACCACAGGCGAGAGCCCATGTCTGT
CAATGGAGGAGCATGCAAAGGTTATAAAGGCTGCCGTAGAGTTTACAAAGCATCGTGTACCTGTAGTAGCAGGCACAGGC
TCTAACTGTACAAAGACAGCTATGCAGCTTTCAAAGGAGGCTGAGGAGTTTGGTGCAGACGGACTGCTCGTTGTCACACC
ATACTACAACAAGGCTACTCAGGCAGGTCTTGTGAGCCACTATTCGCAGATTGCAGACAGCACAAAGTGTCCTATTATCG
TATACAACGTACCGGGACGTACAGGCTGCAACGTGCTTCCGGAGACTATGGCAGAGCTCTTTAAGACAAAGGAAAATATC
GTGGGACTCAAGGAAGCTACAGGAAATCTGGCACAGGCTTCAAAGACAATGTATCTGACAGACGGAAAGCTTGATATGTA
CTCAGGCGAGGATGGTCTCGTAGTGCCTCTTATGTCTATCGGAGCAATCGGTGTAATCTCAGTATGGAGCAATGTAGCCC
CTGCAAAGGTACACAATATGTGCGACAGCTTCTTCAAGGGCGATTTACAGACAGCCTTAGAGCTTCAGAGAGAGGCTCTT
CCACTTGTGGACGCACTCTTCTCAGAGGTAAATCCAATTCCTGTAAAGAAGGCTATGAACCTGATGGGTATGAATGTCGG
ACCTCTTAGAAGCCCTATGTGCGAGATGGGTGAGGATAACGCAAGGAAGCTTGCTGAGGTCATGAAGGCTTATGGCTTAA
AGCTTGCTTAG

Upstream 100 bases:

>100_bases
TAAGGAGCCGGTTTTTTAGCGCTTAGAGGCAGACAGCGGCATACTTATACGTTAAGAGAATCAAATACCGAATAAAGAAA
AGCAAGAAGGAGATAAAATC

Downstream 100 bases:

>100_bases
TACAACGAGAAAGGATACGATAAAATGACAAAGGTAATTATGAATGGCTGCAACGGCAAAATGGGACAGACTATCACAGA
AATCTGTAAGGCTGATGCGG

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 296; Mature: 295

Protein sequence:

>296_residues
MAIFKGAGVAIVTPMYDNEEVNYDKLEELINMQIDNGTDAIIIAGTTGESPCLSMEEHAKVIKAAVEFTKHRVPVVAGTG
SNCTKTAMQLSKEAEEFGADGLLVVTPYYNKATQAGLVSHYSQIADSTKCPIIVYNVPGRTGCNVLPETMAELFKTKENI
VGLKEATGNLAQASKTMYLTDGKLDMYSGEDGLVVPLMSIGAIGVISVWSNVAPAKVHNMCDSFFKGDLQTALELQREAL
PLVDALFSEVNPIPVKKAMNLMGMNVGPLRSPMCEMGEDNARKLAEVMKAYGLKLA

Sequences:

>Translated_296_residues
MAIFKGAGVAIVTPMYDNEEVNYDKLEELINMQIDNGTDAIIIAGTTGESPCLSMEEHAKVIKAAVEFTKHRVPVVAGTG
SNCTKTAMQLSKEAEEFGADGLLVVTPYYNKATQAGLVSHYSQIADSTKCPIIVYNVPGRTGCNVLPETMAELFKTKENI
VGLKEATGNLAQASKTMYLTDGKLDMYSGEDGLVVPLMSIGAIGVISVWSNVAPAKVHNMCDSFFKGDLQTALELQREAL
PLVDALFSEVNPIPVKKAMNLMGMNVGPLRSPMCEMGEDNARKLAEVMKAYGLKLA
>Mature_295_residues
AIFKGAGVAIVTPMYDNEEVNYDKLEELINMQIDNGTDAIIIAGTTGESPCLSMEEHAKVIKAAVEFTKHRVPVVAGTGS
NCTKTAMQLSKEAEEFGADGLLVVTPYYNKATQAGLVSHYSQIADSTKCPIIVYNVPGRTGCNVLPETMAELFKTKENIV
GLKEATGNLAQASKTMYLTDGKLDMYSGEDGLVVPLMSIGAIGVISVWSNVAPAKVHNMCDSFFKGDLQTALELQREALP
LVDALFSEVNPIPVKKAMNLMGMNVGPLRSPMCEMGEDNARKLAEVMKAYGLKLA

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=269, Percent_Identity=26.7657992565056, Blast_Score=114, Evalue=9e-26,
Organism=Homo sapiens, GI13540533, Length=279, Percent_Identity=25.4480286738351, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1788823, Length=292, Percent_Identity=41.0958904109589, Blast_Score=220, Evalue=7e-59,
Organism=Escherichia coli, GI87082415, Length=299, Percent_Identity=29.0969899665552, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1786463, Length=286, Percent_Identity=28.3216783216783, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1789620, Length=277, Percent_Identity=26.7148014440433, Blast_Score=107, Evalue=7e-25,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31819; Mature: 31688

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIFKGAGVAIVTPMYDNEEVNYDKLEELINMQIDNGTDAIIIAGTTGESPCLSMEEHAK
CCEECCCCEEEEECCCCCCCCCHHHHHHHHCEEECCCCCEEEEEECCCCCCCCCHHHHHH
VIKAAVEFTKHRVPVVAGTGSNCTKTAMQLSKEAEEFGADGLLVVTPYYNKATQAGLVSH
HHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH
YSQIADSTKCPIIVYNVPGRTGCNVLPETMAELFKTKENIVGLKEATGNLAQASKTMYLT
HHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHCCCEEEEE
DGKLDMYSGEDGLVVPLMSIGAIGVISVWSNVAPAKVHNMCDSFFKGDLQTALELQREAL
CCEEEEECCCCCCEEHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
PLVDALFSEVNPIPVKKAMNLMGMNVGPLRSPMCEMGEDNARKLAEVMKAYGLKLA
HHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AIFKGAGVAIVTPMYDNEEVNYDKLEELINMQIDNGTDAIIIAGTTGESPCLSMEEHAK
CEECCCCEEEEECCCCCCCCCHHHHHHHHCEEECCCCCEEEEEECCCCCCCCCHHHHHH
VIKAAVEFTKHRVPVVAGTGSNCTKTAMQLSKEAEEFGADGLLVVTPYYNKATQAGLVSH
HHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHH
YSQIADSTKCPIIVYNVPGRTGCNVLPETMAELFKTKENIVGLKEATGNLAQASKTMYLT
HHHHHCCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCHHHCCCEEEEE
DGKLDMYSGEDGLVVPLMSIGAIGVISVWSNVAPAKVHNMCDSFFKGDLQTALELQREAL
CCEEEEECCCCCCEEHHHHHCHHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
PLVDALFSEVNPIPVKKAMNLMGMNVGPLRSPMCEMGEDNARKLAEVMKAYGLKLA
HHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA