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The map label for this gene is ispH [H]

Identifier: 238924000

GI number: 238924000

Start: 1525869

End: 1526984

Strand: Direct

Name: ispH [H]

Synonym: EUBREC_1638

Alternate gene names: 238924000

Gene position: 1525869-1526984 (Clockwise)

Preceding gene: 238923999

Following gene: 238924001

Centisome position: 44.23

GC content: 41.4

Gene sequence:

>1116_bases
ATGTCAGAAATGAGCTTTGAACAAATGCTGGAAGAATCTTTTAAAACTATAAGAAATGGAGAAGTGGTAGAAGGTACCGT
TATTGATGTTAAACCTGACGAGATTTTCTTAAATATTGGATACAAATCAGACGGAATTATTACTAGAAACGAGTACACAA
ATGAGCCGAACGTAGATCTTACTACTGTTGTAAAGGTTGGCGACAAGATGGAAGCCAAGGTAGTTAAGCTTAACGATGGC
GAGGGCCAGGTTATCCTTTCTTACAAGCGCCTTCAGGCAGAGAAGGGCAGCAAGCGTCTTGAGGAGGCTTTTGAGAACCA
GGAAGTATTAAAGGCAAAAGTTACACAGGTATTAGCCGGTGGTGTATGTGTCAGTGTTGATGAGACAAGAGTATTCATCC
CTGCAAGCCTTGTATCAGATACTTATGAGAAGGATCTCAACAAGTTCAAGGATCAGGAGATTGAGTTTATCATCACAGAG
TTCGATCCAAGAAAGAGACGTATTATCGGAAATAGAAAGGTATTACTCGTTGAGCAGAAGGCTAAACAGCAGGAAGAGCT
TCTTGCAAATCTTCACGTTGGCGATGTAATCGAAGGAACAGTTAAGAATGTTACAGATTTCGGTGCATTCATCGATCTTG
GCGGAGTAGACGGATTACTTCATATCTCAGAGATGTCTTGGGGCAGAGTAGAGAACCCTAAGAAGGTATTCACTGTTGGA
CAGACTGTAAGAGTATTTGTTAAGAACATCAATGGTTCTAAGATTGCTCTTTCAATGAAGTTTGATGATGAGAATCCATG
GAATGGTGCAACAGAGAAATTTGCTCCTGGCAATATCGTAAAGGGCAAAGTAGCCAGAATGACAGATTTTGGTGCATTCA
TCGAGCTTGCTCCTGGTGTTGACGCACTTCTTCATGTTTCACAGATTTCAAAGGATCATGTTGAGAAGCCATCAGATGTT
CTCAAGATTGGTCAGGAGGTTGAGGCTAAGGTTGTTGAGTTCAATGAGGACGATAAGAAAATCAGCTTAAGCATGAAGGC
TCTCCTTGATTCAGAGGATGATGGAGCAGATGTTGCAGATGTAAATATCGACGAGGTTGCTTCTGATAACGAGTAG

Upstream 100 bases:

>100_bases
AGTGACGAAATGGATTATACACAAATCAGGTCCAACAATAACGTAGGTATTACAGCAGGGGCTTCAACCCCAAATAATAT
CATTGAGGAGGTTTCAAAGA

Downstream 100 bases:

>100_bases
TTTTTGATTTTAAGGCTGTCATATATAATTATATGGCAGCTTTTATTTGTATCGGGTGGCACATATTGGAGGATTGTGAT
GTTTGATCATTATGAATGGT

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase/S1 RNA-binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSEMSFEQMLEESFKTIRNGEVVEGTVIDVKPDEIFLNIGYKSDGIITRNEYTNEPNVDLTTVVKVGDKMEAKVVKLNDG
EGQVILSYKRLQAEKGSKRLEEAFENQEVLKAKVTQVLAGGVCVSVDETRVFIPASLVSDTYEKDLNKFKDQEIEFIITE
FDPRKRRIIGNRKVLLVEQKAKQQEELLANLHVGDVIEGTVKNVTDFGAFIDLGGVDGLLHISEMSWGRVENPKKVFTVG
QTVRVFVKNINGSKIALSMKFDDENPWNGATEKFAPGNIVKGKVARMTDFGAFIELAPGVDALLHVSQISKDHVEKPSDV
LKIGQEVEAKVVEFNEDDKKISLSMKALLDSEDDGADVADVNIDEVASDNE

Sequences:

>Translated_371_residues
MSEMSFEQMLEESFKTIRNGEVVEGTVIDVKPDEIFLNIGYKSDGIITRNEYTNEPNVDLTTVVKVGDKMEAKVVKLNDG
EGQVILSYKRLQAEKGSKRLEEAFENQEVLKAKVTQVLAGGVCVSVDETRVFIPASLVSDTYEKDLNKFKDQEIEFIITE
FDPRKRRIIGNRKVLLVEQKAKQQEELLANLHVGDVIEGTVKNVTDFGAFIDLGGVDGLLHISEMSWGRVENPKKVFTVG
QTVRVFVKNINGSKIALSMKFDDENPWNGATEKFAPGNIVKGKVARMTDFGAFIELAPGVDALLHVSQISKDHVEKPSDV
LKIGQEVEAKVVEFNEDDKKISLSMKALLDSEDDGADVADVNIDEVASDNE
>Mature_370_residues
SEMSFEQMLEESFKTIRNGEVVEGTVIDVKPDEIFLNIGYKSDGIITRNEYTNEPNVDLTTVVKVGDKMEAKVVKLNDGE
GQVILSYKRLQAEKGSKRLEEAFENQEVLKAKVTQVLAGGVCVSVDETRVFIPASLVSDTYEKDLNKFKDQEIEFIITEF
DPRKRRIIGNRKVLLVEQKAKQQEELLANLHVGDVIEGTVKNVTDFGAFIDLGGVDGLLHISEMSWGRVENPKKVFTVGQ
TVRVFVKNINGSKIALSMKFDDENPWNGATEKFAPGNIVKGKVARMTDFGAFIELAPGVDALLHVSQISKDHVEKPSDVL
KIGQEVEAKVVEFNEDDKKISLSMKALLDSEDDGADVADVNIDEVASDNE

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0539

COG function: function code J; Ribosomal protein S1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 S1 motif domains [H]

Homologues:

Organism=Escherichia coli, GI1787140, Length=353, Percent_Identity=33.1444759206799, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI145693187, Length=70, Percent_Identity=45.7142857142857, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082262, Length=82, Percent_Identity=42.6829268292683, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6323885, Length=264, Percent_Identity=26.8939393939394, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: 16,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR000110
- InterPro:   IPR022967 [H]

Pfam domain/function: PF02401 LYTB; PF00575 S1 [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 41185; Mature: 41054

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEMSFEQMLEESFKTIRNGEVVEGTVIDVKPDEIFLNIGYKSDGIITRNEYTNEPNVDL
CCCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEECCCCCCCEEECCCCCCCCCCCE
TTVVKVGDKMEAKVVKLNDGEGQVILSYKRLQAEKGSKRLEEAFENQEVLKAKVTQVLAG
EEEEECCCCCEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
GVCVSVDETRVFIPASLVSDTYEKDLNKFKDQEIEFIITEFDPRKRRIIGNRKVLLVEQK
CEEEEECCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHCCCCCEEEEEEHH
AKQQEELLANLHVGDVIEGTVKNVTDFGAFIDLGGVDGLLHISEMSWGRVENPKKVFTVG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCCCCCCEEEECC
QTVRVFVKNINGSKIALSMKFDDENPWNGATEKFAPGNIVKGKVARMTDFGAFIELAPGV
CEEEEHEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHEECCCHHEEECCCH
DALLHVSQISKDHVEKPSDVLKIGQEVEAKVVEFNEDDKKISLSMKALLDSEDDGADVAD
HHHHHHHHHHHHHCCCCHHHHHHCHHHEEEEEEECCCCCEEEEEEEEHCCCCCCCCCEEC
VNIDEVASDNE
CCHHHHCCCCC
>Mature Secondary Structure 
SEMSFEQMLEESFKTIRNGEVVEGTVIDVKPDEIFLNIGYKSDGIITRNEYTNEPNVDL
CCCCHHHHHHHHHHHHCCCCEEEEEEEEECCCEEEEECCCCCCCEEECCCCCCCCCCCE
TTVVKVGDKMEAKVVKLNDGEGQVILSYKRLQAEKGSKRLEEAFENQEVLKAKVTQVLAG
EEEEECCCCCEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHC
GVCVSVDETRVFIPASLVSDTYEKDLNKFKDQEIEFIITEFDPRKRRIIGNRKVLLVEQK
CEEEEECCCEEEEEHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHCCCCCEEEEEEHH
AKQQEELLANLHVGDVIEGTVKNVTDFGAFIDLGGVDGLLHISEMSWGRVENPKKVFTVG
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCCCCCCCCEEEECC
QTVRVFVKNINGSKIALSMKFDDENPWNGATEKFAPGNIVKGKVARMTDFGAFIELAPGV
CEEEEHEECCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHEECCCHHEEECCCH
DALLHVSQISKDHVEKPSDVLKIGQEVEAKVVEFNEDDKKISLSMKALLDSEDDGADVAD
HHHHHHHHHHHHHCCCCHHHHHHCHHHEEEEEEECCCCCEEEEEEEEHCCCCCCCCCEEC
VNIDEVASDNE
CCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]