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The map label for this gene is dapA [H]

Identifier: 238923851

GI number: 238923851

Start: 1360772

End: 1361656

Strand: Direct

Name: dapA [H]

Synonym: EUBREC_1479

Alternate gene names: 238923851

Gene position: 1360772-1361656 (Clockwise)

Preceding gene: 238923850

Following gene: 238923852

Centisome position: 39.45

GC content: 45.54

Gene sequence:

>885_bases
ATGTCTCTGTTTAAGGGCGCCGGAGTAGCGCTAATTACTCCTTTCAATGAGGATAACAGTGTAAACTATGAAATGCTTAG
GACGCTGGTGAGAAGGCAGATAGACGGTGGCACTGATGCAATTATCGTGTGTGGCACGACAGGTGAGCCTGCCACAATGA
CAGAGGAAGAAAAGCTTTCGGTAATAAAATGTGTGGTAGACGAGACAGCCGGGCAGATTCCTATAATAGCGGGAACCGGT
GCCAACTGCACACAAAATGTGATAGATTTCTCACAGAAGGCTGAAAAGCTTGGTGTAGACGGTCTGCTTGTTGTCACACC
TTACTACAATAAAGCCACACAGAATGGTCTTTATGCGCACTATGCAGCGATAGCAGGGGCGGTTAGGCTTCCAATCATTA
TGTACAACGTACCGTCGCGCACAGGCTGCAATATACTTCCACAGACTGCGGCAAGGCTTGGCAGGAATTTTGAAAATATA
GTAGGAATCAAGGAAGCGAGTGGCAATATATCGCAGGTTGCAAAGCTAAAGAAGCTGGCAGGAAATGACCTCGATATTTA
TTCGGGAAACGATGACCAGGTCATCCCAATACTCTCACTCGGTGGAATCGGTGTGATATCAGTGCTGTCTAATGTAATGC
CCGCTGCAGTGCACGATATGGTAATGGAATACCTGAATGGAAATATTAAATCAGCACTTGATATCCAGCTTAAATACCTG
GATTTAATAGAGGCACTGTTTTGTGAGGTGAATCCGATTCCTGTAAAGGCAGCTATGAAGCTTTTGGGATATAATGTGGG
AGGACTTCGTCTGCCACTCACGGAGCTTGAGGATGCAAACCGGGCAAGGCTTAAAGAAAGCATGGAAAAACTAAAGGAAA
ATTAG

Upstream 100 bases:

>100_bases
TAATAAAAGAAAATCCTGACATCAGACTTTAATATTTTAGTATAGGTTAAATAGTTTAGTATAAACTAGTTCAGTAAAAT
AGTGTATTTGGGAGGTATAT

Downstream 100 bases:

>100_bases
TGGATATAAAAGGATATTAAAGAAAAATTAAAGGATAAATTAACATATGGGAAAACAAAACTGGAAGCCGGGCAATATGC
TAAACCCGGTGCCGGCTGTG

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSLFKGAGVALITPFNEDNSVNYEMLRTLVRRQIDGGTDAIIVCGTTGEPATMTEEEKLSVIKCVVDETAGQIPIIAGTG
ANCTQNVIDFSQKAEKLGVDGLLVVTPYYNKATQNGLYAHYAAIAGAVRLPIIMYNVPSRTGCNILPQTAARLGRNFENI
VGIKEASGNISQVAKLKKLAGNDLDIYSGNDDQVIPILSLGGIGVISVLSNVMPAAVHDMVMEYLNGNIKSALDIQLKYL
DLIEALFCEVNPIPVKAAMKLLGYNVGGLRLPLTELEDANRARLKESMEKLKEN

Sequences:

>Translated_294_residues
MSLFKGAGVALITPFNEDNSVNYEMLRTLVRRQIDGGTDAIIVCGTTGEPATMTEEEKLSVIKCVVDETAGQIPIIAGTG
ANCTQNVIDFSQKAEKLGVDGLLVVTPYYNKATQNGLYAHYAAIAGAVRLPIIMYNVPSRTGCNILPQTAARLGRNFENI
VGIKEASGNISQVAKLKKLAGNDLDIYSGNDDQVIPILSLGGIGVISVLSNVMPAAVHDMVMEYLNGNIKSALDIQLKYL
DLIEALFCEVNPIPVKAAMKLLGYNVGGLRLPLTELEDANRARLKESMEKLKEN
>Mature_293_residues
SLFKGAGVALITPFNEDNSVNYEMLRTLVRRQIDGGTDAIIVCGTTGEPATMTEEEKLSVIKCVVDETAGQIPIIAGTGA
NCTQNVIDFSQKAEKLGVDGLLVVTPYYNKATQNGLYAHYAAIAGAVRLPIIMYNVPSRTGCNILPQTAARLGRNFENIV
GIKEASGNISQVAKLKKLAGNDLDIYSGNDDQVIPILSLGGIGVISVLSNVMPAAVHDMVMEYLNGNIKSALDIQLKYLD
LIEALFCEVNPIPVKAAMKLLGYNVGGLRLPLTELEDANRARLKESMEKLKEN

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=278, Percent_Identity=26.2589928057554, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI13540533, Length=313, Percent_Identity=24.2811501597444, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1788823, Length=289, Percent_Identity=42.2145328719723, Blast_Score=233, Evalue=1e-62,
Organism=Escherichia coli, GI87082415, Length=277, Percent_Identity=28.158844765343, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1786463, Length=291, Percent_Identity=27.4914089347079, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1789620, Length=244, Percent_Identity=28.2786885245902, Blast_Score=100, Evalue=8e-23,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31628; Mature: 31497

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFKGAGVALITPFNEDNSVNYEMLRTLVRRQIDGGTDAIIVCGTTGEPATMTEEEKLS
CCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHH
VIKCVVDETAGQIPIIAGTGANCTQNVIDFSQKAEKLGVDGLLVVTPYYNKATQNGLYAH
HHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHCCCHHHH
YAAIAGAVRLPIIMYNVPSRTGCNILPQTAARLGRNFENIVGIKEASGNISQVAKLKKLA
HHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHCCCHHHHEEECCCCCCHHHHHHHHHHC
GNDLDIYSGNDDQVIPILSLGGIGVISVLSNVMPAAVHDMVMEYLNGNIKSALDIQLKYL
CCCCEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
DLIEALFCEVNPIPVKAAMKLLGYNVGGLRLPLTELEDANRARLKESMEKLKEN
HHHHHHHHCCCCCCHHHHHHHHCCCCCCEEECHHHHCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLFKGAGVALITPFNEDNSVNYEMLRTLVRRQIDGGTDAIIVCGTTGEPATMTEEEKLS
CCCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHH
VIKCVVDETAGQIPIIAGTGANCTQNVIDFSQKAEKLGVDGLLVVTPYYNKATQNGLYAH
HHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHCCCHHHH
YAAIAGAVRLPIIMYNVPSRTGCNILPQTAARLGRNFENIVGIKEASGNISQVAKLKKLA
HHHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHCCCHHHHEEECCCCCCHHHHHHHHHHC
GNDLDIYSGNDDQVIPILSLGGIGVISVLSNVMPAAVHDMVMEYLNGNIKSALDIQLKYL
CCCCEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
DLIEALFCEVNPIPVKAAMKLLGYNVGGLRLPLTELEDANRARLKESMEKLKEN
HHHHHHHHCCCCCCHHHHHHHHCCCCCCEEECHHHHCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA