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The map label for this gene is ycbM [H]

Identifier: 238923353

GI number: 238923353

Start: 869380

End: 870327

Strand: Direct

Name: ycbM [H]

Synonym: EUBREC_0970

Alternate gene names: 238923353

Gene position: 869380-870327 (Clockwise)

Preceding gene: 238923352

Following gene: 238923354

Centisome position: 25.2

GC content: 43.67

Gene sequence:

>948_bases
ATGATTTGGAAAATACTGACTGTAATACTTGCAGTTTCGGTAGCTGTCTTAATAGCTGTGCTCGTAAAAATAAGGGCACA
GCTTCGTGACATTAACGAACAGCTTGATTTTTTATGCGAAAAGGATACAAATATGCTCCTTTTAACCGATACCAACATGG
CTGATATCGGAAGGCTTAAGGAGCGCATAAACAGATTTTTAGAGCAATGGCACAGGCAACGTGAGGCAGCAGCGAAAAAG
GAGCAGATGATATCTGACACGTACACAAACCTGTCGCACGATATCCGCACTCCGCTTACCTCGCTGGACGGCTATTTTCA
GCTGCTTAGGGATGAGACTGACAAGAGCGCGCAGGAGCATTATATAGATATCATACAGGAGCGCATCACAAGCCTTAAGG
ATATGCTCGAGGAGCTTTTCATGTTCACAAAGCTTAAAAATGACAGCTTCAAGCTAGAGCTGTCTAATTGCTGTGTCAGC
AGACTTTTAAAGCAGACAGTGTTTTCGTATTATGAGGAGTGGAAAAAGCAGGGCATTGAGCCGTCACTTGATATATGTGA
GGACACGATATTTATCACTGCAAATGTGCAGGCGCTCAGGCGGGTGTTTCAGAATGTGATAAAAAATGCACTGGTGCATG
GGCAGAAGAGCATCTGCATACAGATGAAGCAACAGGATTCGTGCAATTGCAGGGCTTCAGATGACGAGCGTACTTCAAAA
AATAGGATTGTCCATATTTTGATTTCAAATGATGTAAAAAATCCTGATGATATAGACGTGGACAAGGTGTTTGAGCGTTT
TTACAAAGCCGATGAGGCTAGGAGCATATCATCGAGCGGGCTTGGGCTTTCGATTGCAAAGGAACTTGTGGAGAGAATGG
GCGGGAGTATTGAAGCAAGGCTTGAGGGGAAGAGGTTTGTTGTGGAAATACTGTTTGAATGTGAATAG

Upstream 100 bases:

>100_bases
ATTTGCGGTAGCCGCTGTGTGGGCAGTGGTGTCACTGATTGCAGTGTACGGTGTATTTAAACGCAGGGATATATAATGTG
TTTTGAATGAGGAATAAAAC

Downstream 100 bases:

>100_bases
TTCACTTTTGTAATGTGATAAATAATATTGACACACATGAAACAAAATGATATACTGTCAAAGTGTTTGCGGGCATGGCG
GAATTGGCAGACGCGCTAGA

Product: sensory transduction protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MIWKILTVILAVSVAVLIAVLVKIRAQLRDINEQLDFLCEKDTNMLLLTDTNMADIGRLKERINRFLEQWHRQREAAAKK
EQMISDTYTNLSHDIRTPLTSLDGYFQLLRDETDKSAQEHYIDIIQERITSLKDMLEELFMFTKLKNDSFKLELSNCCVS
RLLKQTVFSYYEEWKKQGIEPSLDICEDTIFITANVQALRRVFQNVIKNALVHGQKSICIQMKQQDSCNCRASDDERTSK
NRIVHILISNDVKNPDDIDVDKVFERFYKADEARSISSSGLGLSIAKELVERMGGSIEARLEGKRFVVEILFECE

Sequences:

>Translated_315_residues
MIWKILTVILAVSVAVLIAVLVKIRAQLRDINEQLDFLCEKDTNMLLLTDTNMADIGRLKERINRFLEQWHRQREAAAKK
EQMISDTYTNLSHDIRTPLTSLDGYFQLLRDETDKSAQEHYIDIIQERITSLKDMLEELFMFTKLKNDSFKLELSNCCVS
RLLKQTVFSYYEEWKKQGIEPSLDICEDTIFITANVQALRRVFQNVIKNALVHGQKSICIQMKQQDSCNCRASDDERTSK
NRIVHILISNDVKNPDDIDVDKVFERFYKADEARSISSSGLGLSIAKELVERMGGSIEARLEGKRFVVEILFECE
>Mature_315_residues
MIWKILTVILAVSVAVLIAVLVKIRAQLRDINEQLDFLCEKDTNMLLLTDTNMADIGRLKERINRFLEQWHRQREAAAKK
EQMISDTYTNLSHDIRTPLTSLDGYFQLLRDETDKSAQEHYIDIIQERITSLKDMLEELFMFTKLKNDSFKLELSNCCVS
RLLKQTVFSYYEEWKKQGIEPSLDICEDTIFITANVQALRRVFQNVIKNALVHGQKSICIQMKQQDSCNCRASDDERTSK
NRIVHILISNDVKNPDDIDVDKVFERFYKADEARSISSSGLGLSIAKELVERMGGSIEARLEGKRFVVEILFECE

Specific function: Member of the two-component regulatory system ycbM/ycbL. Probably activates ycbL by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=271, Percent_Identity=21.7712177121771, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786783, Length=320, Percent_Identity=21.5625, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI48994928, Length=235, Percent_Identity=22.9787234042553, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1788713, Length=267, Percent_Identity=22.4719101123595, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 36482; Mature: 36482

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIWKILTVILAVSVAVLIAVLVKIRAQLRDINEQLDFLCEKDTNMLLLTDTNMADIGRLK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
ERINRFLEQWHRQREAAAKKEQMISDTYTNLSHDIRTPLTSLDGYFQLLRDETDKSAQEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
YIDIIQERITSLKDMLEELFMFTKLKNDSFKLELSNCCVSRLLKQTVFSYYEEWKKQGIE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
PSLDICEDTIFITANVQALRRVFQNVIKNALVHGQKSICIQMKQQDSCNCRASDDERTSK
CCHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCCCCCCCCCCCCC
NRIVHILISNDVKNPDDIDVDKVFERFYKADEARSISSSGLGLSIAKELVERMGGSIEAR
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEE
LEGKRFVVEILFECE
ECCHHHHHHHHHHCC
>Mature Secondary Structure
MIWKILTVILAVSVAVLIAVLVKIRAQLRDINEQLDFLCEKDTNMLLLTDTNMADIGRLK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHH
ERINRFLEQWHRQREAAAKKEQMISDTYTNLSHDIRTPLTSLDGYFQLLRDETDKSAQEH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
YIDIIQERITSLKDMLEELFMFTKLKNDSFKLELSNCCVSRLLKQTVFSYYEEWKKQGIE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCC
PSLDICEDTIFITANVQALRRVFQNVIKNALVHGQKSICIQMKQQDSCNCRASDDERTSK
CCHHHHCCCEEEEECHHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCCCCCCCCCCCCC
NRIVHILISNDVKNPDDIDVDKVFERFYKADEARSISSSGLGLSIAKELVERMGGSIEAR
CCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEE
LEGKRFVVEILFECE
ECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]