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The map label for this gene is pepC [H]

Identifier: 238923155

GI number: 238923155

Start: 688840

End: 690081

Strand: Direct

Name: pepC [H]

Synonym: EUBREC_0748

Alternate gene names: 238923155

Gene position: 688840-690081 (Clockwise)

Preceding gene: 238923154

Following gene: 238923156

Centisome position: 19.97

GC content: 31.08

Gene sequence:

>1242_bases
GTGGATAAAATGGCAGATAATGATTTGATTAGAAACAAAGGAATAATGAGTGCTGCACAAACCATGTGGACGATAGATTT
CGATTCTGAACAGTCTTTAGAAATCGGCAAGGTACAAAATCAGAAATTTACTGGGAAATGCTGGATATACGCAGGACTTA
ATTTATTAAGAATATTGGCAAATAGAAAAAACAGTAGGACTAGCATTATTCTTTCTGCTAACTATATAGCTTATTATGAC
AAATACGAAAAATCAAAATATTTTTTTGAAAAAGTAATAGAGACAATGAAGTTGCCAAGTGATAATAGATTAGTTGAACA
TTTATTTAAAAATCCATGTCCAGATGCAGGACAATGGGCAATGTTTAACAACATTATAAAGAAATATGGTATTGTTCCAC
AAGAATCAATGCCAGATACATATTCGGCATTAGATACAAATCAAATGAATATTTGTTTATCGACTATTTTGCGAGATTCT
GGGTGTAATATAAGAAAGTTGAATATGAAAGGTGCAAGTTTAGAACAAATCAATAGTGAAGTTGAAACGAAAATGGATGA
AATTAGAAGAATATTAAGCTTGTGCCTTGGAGAACCACCAACTGAATTTCAGTATGGAAAGATGGAAAAAAAATACTCAC
CCATTTCGTATTATAAATCAGAGATAGGAGTAGATTTAGATAAATATTTGTGCTTGATTAATGCTCCTATGTTAAAAGTA
CCAATGTATAAAAAGTATTGTATTCAAAATCTTAATAATATGTCCGAAGGAAAGAAGATAGAGTATATCAATCTACCCAT
AGAAACTTTAAAAGAAAAAGTCATTGAGCAGATAGCCGATGGAACGCCAGTGTGGTTTGGCTGTGATGCAGGAAAAATGA
TAGATAAAAAAACAGGAATTATGGATGATAATACTTTTAATGTATCACATATACTAAATACTTCGTATTTATTTTCAAAG
GGAGAACAATTAGAATACCATCAGTCTGAAATGAATCATGCTATGTTGATTATCGGGATTATATTAAAGGACCAGAAGGT
AGTTGGATTTAAAGTAGAAGATTCCCATGGAAATCAAGTTGGTAAGGATGGGTACTTTTATATGTCGATAGATTGGTTTG
AAAAGTATGTTTATCAAGTAGTGATTGATAAACGATATTTATCGATGGATGAAGAAAAAATATTGGATGGAGAAAGTTTA
TATTTAATGCCATGGAATCCAATGGGAACATTGGCTAACTAA

Upstream 100 bases:

>100_bases
TTGGAATGTACGATAAATAGTACTTTATATCCAGAAATGATTGAATCAATTTTAAGTGAACAAAAATTGATAAATGACTT
TCTAAATATGAAAATAATTG

Downstream 100 bases:

>100_bases
ATTGTATTTGCGTTTGAAAAGTACATTTGTTTTGTGGTACAACTTCGAGTGCAGTTTTCAGATGCAAATGTGTCTGGAAT
ACTAAAGAAAGGAGGTATCT

Product: cysteine aminopeptidase C2 (bleomycin hydrolase)

Products: NA

Alternate protein names: Bleomycin hydrolase [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MDKMADNDLIRNKGIMSAAQTMWTIDFDSEQSLEIGKVQNQKFTGKCWIYAGLNLLRILANRKNSRTSIILSANYIAYYD
KYEKSKYFFEKVIETMKLPSDNRLVEHLFKNPCPDAGQWAMFNNIIKKYGIVPQESMPDTYSALDTNQMNICLSTILRDS
GCNIRKLNMKGASLEQINSEVETKMDEIRRILSLCLGEPPTEFQYGKMEKKYSPISYYKSEIGVDLDKYLCLINAPMLKV
PMYKKYCIQNLNNMSEGKKIEYINLPIETLKEKVIEQIADGTPVWFGCDAGKMIDKKTGIMDDNTFNVSHILNTSYLFSK
GEQLEYHQSEMNHAMLIIGIILKDQKVVGFKVEDSHGNQVGKDGYFYMSIDWFEKYVYQVVIDKRYLSMDEEKILDGESL
YLMPWNPMGTLAN

Sequences:

>Translated_413_residues
MDKMADNDLIRNKGIMSAAQTMWTIDFDSEQSLEIGKVQNQKFTGKCWIYAGLNLLRILANRKNSRTSIILSANYIAYYD
KYEKSKYFFEKVIETMKLPSDNRLVEHLFKNPCPDAGQWAMFNNIIKKYGIVPQESMPDTYSALDTNQMNICLSTILRDS
GCNIRKLNMKGASLEQINSEVETKMDEIRRILSLCLGEPPTEFQYGKMEKKYSPISYYKSEIGVDLDKYLCLINAPMLKV
PMYKKYCIQNLNNMSEGKKIEYINLPIETLKEKVIEQIADGTPVWFGCDAGKMIDKKTGIMDDNTFNVSHILNTSYLFSK
GEQLEYHQSEMNHAMLIIGIILKDQKVVGFKVEDSHGNQVGKDGYFYMSIDWFEKYVYQVVIDKRYLSMDEEKILDGESL
YLMPWNPMGTLAN
>Mature_413_residues
MDKMADNDLIRNKGIMSAAQTMWTIDFDSEQSLEIGKVQNQKFTGKCWIYAGLNLLRILANRKNSRTSIILSANYIAYYD
KYEKSKYFFEKVIETMKLPSDNRLVEHLFKNPCPDAGQWAMFNNIIKKYGIVPQESMPDTYSALDTNQMNICLSTILRDS
GCNIRKLNMKGASLEQINSEVETKMDEIRRILSLCLGEPPTEFQYGKMEKKYSPISYYKSEIGVDLDKYLCLINAPMLKV
PMYKKYCIQNLNNMSEGKKIEYINLPIETLKEKVIEQIADGTPVWFGCDAGKMIDKKTGIMDDNTFNVSHILNTSYLFSK
GEQLEYHQSEMNHAMLIIGIILKDQKVVGFKVEDSHGNQVGKDGYFYMSIDWFEKYVYQVVIDKRYLSMDEEKILDGESL
YLMPWNPMGTLAN

Specific function: Unknown

COG id: COG3579

COG function: function code E; Aminopeptidase C

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase C1 family [H]

Homologues:

Organism=Homo sapiens, GI4557367, Length=421, Percent_Identity=33.2541567695962, Blast_Score=258, Evalue=8e-69,
Organism=Saccharomyces cerevisiae, GI6324090, Length=404, Percent_Identity=32.4257425742574, Blast_Score=201, Evalue=2e-52,
Organism=Drosophila melanogaster, GI24640588, Length=403, Percent_Identity=32.0099255583127, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI161077632, Length=403, Percent_Identity=32.0099255583127, Blast_Score=224, Evalue=6e-59,
Organism=Drosophila melanogaster, GI161077630, Length=359, Percent_Identity=32.5905292479109, Blast_Score=202, Evalue=5e-52,
Organism=Drosophila melanogaster, GI20130175, Length=428, Percent_Identity=24.7663551401869, Blast_Score=145, Evalue=7e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000169
- InterPro:   IPR004134 [H]

Pfam domain/function: PF03051 Peptidase_C1_2 [H]

EC number: =3.4.22.40 [H]

Molecular weight: Translated: 47685; Mature: 47685

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00139 THIOL_PROTEASE_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKMADNDLIRNKGIMSAAQTMWTIDFDSEQSLEIGKVQNQKFTGKCWIYAGLNLLRILA
CCCCCCCHHHHCCCHHHHHHEEEEEECCCCCCCEECCCCCCCCCCEEEEEHHHHHHHHHH
NRKNSRTSIILSANYIAYYDKYEKSKYFFEKVIETMKLPSDNRLVEHLFKNPCPDAGQWA
CCCCCCEEEEEEECEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHH
MFNNIIKKYGIVPQESMPDTYSALDTNQMNICLSTILRDSGCNIRKLNMKGASLEQINSE
HHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHH
VETKMDEIRRILSLCLGEPPTEFQYGKMEKKYSPISYYKSEIGVDLDKYLCLINAPMLKV
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHCCCHHHHHHHHCCCHHCC
PMYKKYCIQNLNNMSEGKKIEYINLPIETLKEKVIEQIADGTPVWFGCDAGKMIDKKTGI
CHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCC
MDDNTFNVSHILNTSYLFSKGEQLEYHQSEMNHAMLIIGIILKDQKVVGFKVEDSHGNQV
CCCCCEEHHHHHCCHHHHCCCCCHHHHHHHCCCEEEEEEEEEECCEEEEEEEECCCCCCC
GKDGYFYMSIDWFEKYVYQVVIDKRYLSMDEEKILDGESLYLMPWNPMGTLAN
CCCCEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MDKMADNDLIRNKGIMSAAQTMWTIDFDSEQSLEIGKVQNQKFTGKCWIYAGLNLLRILA
CCCCCCCHHHHCCCHHHHHHEEEEEECCCCCCCEECCCCCCCCCCEEEEEHHHHHHHHHH
NRKNSRTSIILSANYIAYYDKYEKSKYFFEKVIETMKLPSDNRLVEHLFKNPCPDAGQWA
CCCCCCEEEEEEECEEEEEHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCHH
MFNNIIKKYGIVPQESMPDTYSALDTNQMNICLSTILRDSGCNIRKLNMKGASLEQINSE
HHHHHHHHHCCCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHH
VETKMDEIRRILSLCLGEPPTEFQYGKMEKKYSPISYYKSEIGVDLDKYLCLINAPMLKV
HHHHHHHHHHHHHHHCCCCCCCCCCCCHHHCCCCHHHHHHHHCCCHHHHHHHHCCCHHCC
PMYKKYCIQNLNNMSEGKKIEYINLPIETLKEKVIEQIADGTPVWFGCDAGKMIDKKTGI
CHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCC
MDDNTFNVSHILNTSYLFSKGEQLEYHQSEMNHAMLIIGIILKDQKVVGFKVEDSHGNQV
CCCCCEEHHHHHCCHHHHCCCCCHHHHHHHCCCEEEEEEEEEECCEEEEEEEECCCCCCC
GKDGYFYMSIDWFEKYVYQVVIDKRYLSMDEEKILDGESLYLMPWNPMGTLAN
CCCCEEEEEHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7851736 [H]