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The map label for this gene is yvyE [H]

Identifier: 238923112

GI number: 238923112

Start: 651516

End: 652223

Strand: Direct

Name: yvyE [H]

Synonym: EUBREC_0704

Alternate gene names: 238923112

Gene position: 651516-652223 (Clockwise)

Preceding gene: 238923110

Following gene: 238923113

Centisome position: 18.89

GC content: 47.88

Gene sequence:

>708_bases
ATGCATGAGTGTAATCAGGCAATATCAGGATGGAAAGAATATCATATGTCAGAGAATACTATAAGCCTGTACGTGTACAA
GGGCGGACAGGGTGAGATAACAGAGAAGAAATCGAGGTTTATAGCAACCGTAAGGCCGGTAGAGTCTGAGGATGAGGCTG
TAAGCTTCATCAATGAGACGAAAAAGAAATACTGGGATGCAAGGCACAACTGCAGTGCCTTTGTTATAGGAAAGAGACAG
GAGCTGACCAGATGCTCGGATGACGGGGAGCCTGCAGGCACCGCAGGCCGTCCTATGCTTGATGTGCTCCTTAAGGAAAA
TATCCACAATGCCGCTGTTGTAGTAACGAGGTACTTCGGTGGGGTGCTGCTTGGCACAGGCGGACTGGTGCGTGCGTATC
AGCAAGCCACAAAGGCGGGGCTTTCGGCAAGTGAGATAATAGAGAAGAAGGAGGGTGCAGTACTGTTTATCAGGACGGAC
TATACCGGAATCGGAAGACTTCAGTATCTGTTTGCACAGGAGAAGATTACGGTGATGGACACAGCGTATGAGGCGGATGT
GCTCGTAAAAGCCGTTATCCCGGAAAATGATAAAAAACGCATAGAGAAAACAATCATAGAGCAGACAAACGGCACGGCAA
AGCTTGAGTGGGGTGATGAGGTGACATTTGCTGAATATGATGGCGAGGTGTTGCTGTTTAAAAATTAG

Upstream 100 bases:

>100_bases
AACAGTATACATTATTATATCAAATATAGCATTTAAATGCAATTTACAGATTGGTTTTCATATTATATAATACAGGTAAC
AATTATAAAGTGTCTTTAAG

Downstream 100 bases:

>100_bases
CCGGTGCTCACATTTTAGCAGGACAAGCAGAATTTATATTCAATTACATTCAATTAAAATAAAAAAATACTTGACACTAT
ATGACCACATGTGTATAATA

Product: thymidylate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MHECNQAISGWKEYHMSENTISLYVYKGGQGEITEKKSRFIATVRPVESEDEAVSFINETKKKYWDARHNCSAFVIGKRQ
ELTRCSDDGEPAGTAGRPMLDVLLKENIHNAAVVVTRYFGGVLLGTGGLVRAYQQATKAGLSASEIIEKKEGAVLFIRTD
YTGIGRLQYLFAQEKITVMDTAYEADVLVKAVIPENDKKRIEKTIIEQTNGTAKLEWGDEVTFAEYDGEVLLFKN

Sequences:

>Translated_235_residues
MHECNQAISGWKEYHMSENTISLYVYKGGQGEITEKKSRFIATVRPVESEDEAVSFINETKKKYWDARHNCSAFVIGKRQ
ELTRCSDDGEPAGTAGRPMLDVLLKENIHNAAVVVTRYFGGVLLGTGGLVRAYQQATKAGLSASEIIEKKEGAVLFIRTD
YTGIGRLQYLFAQEKITVMDTAYEADVLVKAVIPENDKKRIEKTIIEQTNGTAKLEWGDEVTFAEYDGEVLLFKN
>Mature_235_residues
MHECNQAISGWKEYHMSENTISLYVYKGGQGEITEKKSRFIATVRPVESEDEAVSFINETKKKYWDARHNCSAFVIGKRQ
ELTRCSDDGEPAGTAGRPMLDVLLKENIHNAAVVVTRYFGGVLLGTGGLVRAYQQATKAGLSASEIIEKKEGAVLFIRTD
YTGIGRLQYLFAQEKITVMDTAYEADVLVKAVIPENDKKRIEKTIIEQTNGTAKLEWGDEVTFAEYDGEVLLFKN

Specific function: Unknown

COG id: COG1739

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IMPACT family [H]

Homologues:

Organism=Escherichia coli, GI87082338, Length=182, Percent_Identity=32.4175824175824, Blast_Score=82, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR020568
- InterPro:   IPR000640
- InterPro:   IPR015796
- InterPro:   IPR015269
- InterPro:   IPR020569
- InterPro:   IPR001498 [H]

Pfam domain/function: PF09186 DUF1949; PF01205 UPF0029 [H]

EC number: NA

Molecular weight: Translated: 26285; Mature: 26285

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00910 UPF0029

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHECNQAISGWKEYHMSENTISLYVYKGGQGEITEKKSRFIATVRPVESEDEAVSFINET
CCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHEEEEECCCCCCHHHHHHHHHH
KKKYWDARHNCSAFVIGKRQELTRCSDDGEPAGTAGRPMLDVLLKENIHNAAVVVTRYFG
HHHHHCCCCCCCEEEEECHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCHHEEEEHHHC
GVLLGTGGLVRAYQQATKAGLSASEIIEKKEGAVLFIRTDYTGIGRLQYLFAQEKITVMD
CEEECCCHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCHHEEEHHCCCEEEEE
TAYEADVLVKAVIPENDKKRIEKTIIEQTNGTAKLEWGDEVTFAEYDGEVLLFKN
CCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCEEEEEEC
>Mature Secondary Structure
MHECNQAISGWKEYHMSENTISLYVYKGGQGEITEKKSRFIATVRPVESEDEAVSFINET
CCHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCHHHHHEEEEECCCCCCHHHHHHHHHH
KKKYWDARHNCSAFVIGKRQELTRCSDDGEPAGTAGRPMLDVLLKENIHNAAVVVTRYFG
HHHHHCCCCCCCEEEEECHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCHHEEEEHHHC
GVLLGTGGLVRAYQQATKAGLSASEIIEKKEGAVLFIRTDYTGIGRLQYLFAQEKITVMD
CEEECCCHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEECCCCCCHHEEEHHCCCEEEEE
TAYEADVLVKAVIPENDKKRIEKTIIEQTNGTAKLEWGDEVTFAEYDGEVLLFKN
CCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEECCCCEEEEEECCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 3141378; 8313894 [H]