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The map label for this gene is yesN [H]

Identifier: 238922893

GI number: 238922893

Start: 438287

End: 439891

Strand: Direct

Name: yesN [H]

Synonym: EUBREC_0481

Alternate gene names: 238922893

Gene position: 438287-439891 (Clockwise)

Preceding gene: 238922892

Following gene: 238922894

Centisome position: 12.71

GC content: 44.74

Gene sequence:

>1605_bases
ATGTATACATTATTACTGGTTGATGACGAAGAGGATGTAATAGAGGTAATCGAGAGAAAGGTATCCTGGGAGCAGATTGG
TTTTCATGTTGTAGGACATGCGGGAAATGGCTTCAAGGCGCTTGAGATGATGGAGGACATGCAGCCGGATGTTGTGATGA
CTGACATACGTATGCCTTACATGGACGGACTTGAGCTGTGCAGTAACATCAGGCAGAGGTTTCCTGCGACGAAGCTCTTG
CTTTTCACAGGCTTTGACGATTTTGAGTATGCAAAGGAGGCAGTACATCTCGAGATAGAGGAGTATATTTTAAAGCCACT
CAATCTGGCTGAAATCACAGAGGTATTCAAAAAGCTTAAGACAAAGCTGGATGATGAGCTGAACGAGAAGAAAAACACAG
ACATATTGAAGCAGTATTATGCAGCATCACTGCCTGTTTTGCAGTCAAACTTTTATACGACACTTATCGAGGGACGCATA
CCGGAAAATGAGCTGGGCAGGTACATGCGTGACTATAAGATTGTGCTTGAGGGACCATATTACTGCTGTATTATCATACA
TACCTCCGCAAGTCAGATGCCGCAGGGCATGGATATCAGACTGCTTGCAGTGTCAGTAGAGCGACAGGCACAGGCTGATT
TAAAGGAGCGCTGGAATGGCAGGATTTTTAACTATCTCGGTGATACGGTCATGATAGCCCAGCTTGTGCAGCAGGAGGAT
ATCTCTGAGCTGACAGATGAGTGCGACAGATTCTGCAAATATGTAAATCATGTAATGGGAGCAAAGGTAACTGTCGGAAT
CGGACAGGTGTGCGAAAATGTACAGGAGCTGGTGAGCTCTTATCAGAGTGCGAGGGAGGCAGTATCCTACAGGGTGCTTT
ATGGCAGCAACAGGGCAATAAACATGACAGAGGTTGAGCCACAGCGACGTATATCAAAGGATGGCGATGAGGGAAATGAG
CTGTCAAATTTATTTAAAATGATTTGTATCGGCAAGATAGAGGATGTGGGACAGGCTGTTGAGGCGTATATGCAGCACAA
TTTTATGTCGCAGCAGTCACTTGAGAACTACCATGTGGCAGTAATGGAGCTGATCAGTGAGTTATATCATTTCATGAGCA
ATAATGAGCTAAATGCGCAGGAAATATCGGGAAGTGTAGGCAGGCTTTATAATGAGCTCTCCAATTTTGAGCCGGTGGTG
CTCAAGCAGTGGCTTTTGGATTTTTCAAGCAGGCTGCACGACGATATGGCTGATGCCAGATACAACTCCAAGAAGTCACT
CATAGACAGTGCAAAGGATTATGTGCACAGGAATTACAGAAGTGTGGACCTTGGACTTGACGATACATGTAAGGAATTAG
GAGTATCTAACTCGTATTTTTCAAGTCTGTTCAAGAAGGAAACCGGCAGCTCGTTTGTGGAGTATCTGACTGATTACAGA
ATGGACAAGGCTGCCAGAATGCTTGTGGAGACAGACGACAAGAGCTATGTCATAGCCCAGAATGTAGGCTATGCGGATCC
GAACTATTTCAGTTATGTTTTTAAGAGAAAGTATGGGGTTTCCCCATCCAGGTACAGGACAGAGTATGAGAAGAATAAGG
TATAA

Upstream 100 bases:

>100_bases
CTATACAGACAGATTTTATTATCCGGGGGATAAATTTATGCTACACACGGATTTTATGGTGTATGCAGTTCAATAATTAC
AAGCAGGGAGAAGACATAAA

Downstream 100 bases:

>100_bases
ATCAGGCAATATACAATCCATAATAATGCTCTCATTCTCACTGCTGTCGTTTGCAATAATGCTTGTCACAGTTGTGGTGA
TGTATATAAAATTTGCCGAT

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MYTLLLVDDEEDVIEVIERKVSWEQIGFHVVGHAGNGFKALEMMEDMQPDVVMTDIRMPYMDGLELCSNIRQRFPATKLL
LFTGFDDFEYAKEAVHLEIEEYILKPLNLAEITEVFKKLKTKLDDELNEKKNTDILKQYYAASLPVLQSNFYTTLIEGRI
PENELGRYMRDYKIVLEGPYYCCIIIHTSASQMPQGMDIRLLAVSVERQAQADLKERWNGRIFNYLGDTVMIAQLVQQED
ISELTDECDRFCKYVNHVMGAKVTVGIGQVCENVQELVSSYQSAREAVSYRVLYGSNRAINMTEVEPQRRISKDGDEGNE
LSNLFKMICIGKIEDVGQAVEAYMQHNFMSQQSLENYHVAVMELISELYHFMSNNELNAQEISGSVGRLYNELSNFEPVV
LKQWLLDFSSRLHDDMADARYNSKKSLIDSAKDYVHRNYRSVDLGLDDTCKELGVSNSYFSSLFKKETGSSFVEYLTDYR
MDKAARMLVETDDKSYVIAQNVGYADPNYFSYVFKRKYGVSPSRYRTEYEKNKV

Sequences:

>Translated_534_residues
MYTLLLVDDEEDVIEVIERKVSWEQIGFHVVGHAGNGFKALEMMEDMQPDVVMTDIRMPYMDGLELCSNIRQRFPATKLL
LFTGFDDFEYAKEAVHLEIEEYILKPLNLAEITEVFKKLKTKLDDELNEKKNTDILKQYYAASLPVLQSNFYTTLIEGRI
PENELGRYMRDYKIVLEGPYYCCIIIHTSASQMPQGMDIRLLAVSVERQAQADLKERWNGRIFNYLGDTVMIAQLVQQED
ISELTDECDRFCKYVNHVMGAKVTVGIGQVCENVQELVSSYQSAREAVSYRVLYGSNRAINMTEVEPQRRISKDGDEGNE
LSNLFKMICIGKIEDVGQAVEAYMQHNFMSQQSLENYHVAVMELISELYHFMSNNELNAQEISGSVGRLYNELSNFEPVV
LKQWLLDFSSRLHDDMADARYNSKKSLIDSAKDYVHRNYRSVDLGLDDTCKELGVSNSYFSSLFKKETGSSFVEYLTDYR
MDKAARMLVETDDKSYVIAQNVGYADPNYFSYVFKRKYGVSPSRYRTEYEKNKV
>Mature_534_residues
MYTLLLVDDEEDVIEVIERKVSWEQIGFHVVGHAGNGFKALEMMEDMQPDVVMTDIRMPYMDGLELCSNIRQRFPATKLL
LFTGFDDFEYAKEAVHLEIEEYILKPLNLAEITEVFKKLKTKLDDELNEKKNTDILKQYYAASLPVLQSNFYTTLIEGRI
PENELGRYMRDYKIVLEGPYYCCIIIHTSASQMPQGMDIRLLAVSVERQAQADLKERWNGRIFNYLGDTVMIAQLVQQED
ISELTDECDRFCKYVNHVMGAKVTVGIGQVCENVQELVSSYQSAREAVSYRVLYGSNRAINMTEVEPQRRISKDGDEGNE
LSNLFKMICIGKIEDVGQAVEAYMQHNFMSQQSLENYHVAVMELISELYHFMSNNELNAQEISGSVGRLYNELSNFEPVV
LKQWLLDFSSRLHDDMADARYNSKKSLIDSAKDYVHRNYRSVDLGLDDTCKELGVSNSYFSSLFKKETGSSFVEYLTDYR
MDKAARMLVETDDKSYVIAQNVGYADPNYFSYVFKRKYGVSPSRYRTEYEKNKV

Specific function: Member of the two-component regulatory system yesM/yesN [H]

COG id: COG4753

COG function: function code T; Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=115, Percent_Identity=33.0434782608696, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790299, Length=113, Percent_Identity=30.9734513274336, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00165 HTH_AraC; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 61674; Mature: 61674

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTLLLVDDEEDVIEVIERKVSWEQIGFHVVGHAGNGFKALEMMEDMQPDVVMTDIRMPY
CEEEEEECCCHHHHHHHHHHCCHHHHCEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCH
MDGLELCSNIRQRFPATKLLLFTGFDDFEYAKEAVHLEIEEYILKPLNLAEITEVFKKLK
HHHHHHHHHHHHHCCHHEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TKLDDELNEKKNTDILKQYYAASLPVLQSNFYTTLIEGRIPENELGRYMRDYKIVLEGPY
HHHHHHHHHHCCHHHHHHHHHHCCCHHHCCHHHHHHCCCCCHHHHHHHHHHCEEEEECCE
YCCIIIHTSASQMPQGMDIRLLAVSVERQAQADLKERWNGRIFNYLGDTVMIAQLVQQED
EEEEEEECCHHCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ISELTDECDRFCKYVNHVMGAKVTVGIGQVCENVQELVSSYQSAREAVSYRVLYGSNRAI
HHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEE
NMTEVEPQRRISKDGDEGNELSNLFKMICIGKIEDVGQAVEAYMQHNFMSQQSLENYHVA
EECCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMELISELYHFMSNNELNAQEISGSVGRLYNELSNFEPVVLKQWLLDFSSRLHDDMADAR
HHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
YNSKKSLIDSAKDYVHRNYRSVDLGLDDTCKELGVSNSYFSSLFKKETGSSFVEYLTDYR
CCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHH
MDKAARMLVETDDKSYVIAQNVGYADPNYFSYVFKRKYGVSPSRYRTEYEKNKV
HHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MYTLLLVDDEEDVIEVIERKVSWEQIGFHVVGHAGNGFKALEMMEDMQPDVVMTDIRMPY
CEEEEEECCCHHHHHHHHHHCCHHHHCEEEEECCCCCHHHHHHHHHCCCCEEEECCCCCH
MDGLELCSNIRQRFPATKLLLFTGFDDFEYAKEAVHLEIEEYILKPLNLAEITEVFKKLK
HHHHHHHHHHHHHCCHHEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
TKLDDELNEKKNTDILKQYYAASLPVLQSNFYTTLIEGRIPENELGRYMRDYKIVLEGPY
HHHHHHHHHHCCHHHHHHHHHHCCCHHHCCHHHHHHCCCCCHHHHHHHHHHCEEEEECCE
YCCIIIHTSASQMPQGMDIRLLAVSVERQAQADLKERWNGRIFNYLGDTVMIAQLVQQED
EEEEEEECCHHCCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ISELTDECDRFCKYVNHVMGAKVTVGIGQVCENVQELVSSYQSAREAVSYRVLYGSNRAI
HHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCEE
NMTEVEPQRRISKDGDEGNELSNLFKMICIGKIEDVGQAVEAYMQHNFMSQQSLENYHVA
EECCCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMELISELYHFMSNNELNAQEISGSVGRLYNELSNFEPVVLKQWLLDFSSRLHDDMADAR
HHHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
YNSKKSLIDSAKDYVHRNYRSVDLGLDDTCKELGVSNSYFSSLFKKETGSSFVEYLTDYR
CCHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHH
MDKAARMLVETDDKSYVIAQNVGYADPNYFSYVFKRKYGVSPSRYRTEYEKNKV
HHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]