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The map label for this gene is norM [H]

Identifier: 238922878

GI number: 238922878

Start: 424569

End: 425954

Strand: Direct

Name: norM [H]

Synonym: EUBREC_0466

Alternate gene names: 238922878

Gene position: 424569-425954 (Clockwise)

Preceding gene: 238922877

Following gene: 238922879

Centisome position: 12.31

GC content: 45.31

Gene sequence:

>1386_bases
ATGCATAAATTCAGACAAAAATATATAGGAGACAAAGCATTTTATAAGCGCTATCTCATGCTGGCCATACCAATGATAAT
CCAGAATGCAATCACAAATCTGGTAAGCTTTCTGGACAACATTATGGTAGGACAGCTTGGTACAGAGCAGATGTCGGGAG
TAGCAATCGTAAACCAGCTCATATTTGTGTACAATCTGGCAGTGTTTGGGGCGGTGTCAGCGGCAAGTATATTCGGAGCA
CAGTATTTTGGCAAGGGAAATCATAAGGGGCATATGTATTCCTTCAGATTCAAGCTGTATGCAGCGCTGCTTGTTACAGC
AATAGCGATGACACTGTTTATCACGAACGGAACAGGTTTCATATCACTTTATCTGACAGATACGGCAGGAAACGGTGCCA
CGGAGGTAGCACTGGCATATGGAAAGGAATATCTGGAAATTGTTATGATAGGTCTCATACCGTTTGCGGTGACGCAGGCC
TATGCGACAAACATAAAGGAAACAGGACAGACTTTTGTACCGATGGTTGCAAGCTTTGCAGCAGTTGGAAGCAATGCGGT
GCTTGATTTTCTGCTCATCTTCGGAATAGGACCGATACCAAAGCTGGGTGTGGCGGGAGCCGCTATTGCCACTGTGATGT
CGCGATATATTGAGACAATAATAGTTGTGCTGTGGGCGCATAAAAACAGGGATAAGAATAGATATCTCGAGGGCGCTTAC
AGAGGAATAGGAATGCCGTTTGGTGAGTTTAAGACTATATTCATCAAGGGACTGCCACTCATGCTCAATGAGCTTTTATG
GGCAGCAGGCATGACAACGGTTACACAGTGCTATTCAGTACGAGGACTCTCGGTAATCGCAGGTTTAAACATTGCGACAA
CGATAACAAACCTTTTCAATATCGTGTTTATACAGCTTGGCGCATGCATCAGCATAGTTGTAGGGCAGTATCTTGGAGCC
GGTGAGCTTGAAAAGGCAAAGGATGCGGATAACAAGATGATAGTGTTCAGTGTGTTCTGCTGTTCTGTAATGGCGGCGGT
CATGCTTCTGGTAGGCGGATTTTTCCCTCAGATATATAACACAACAGATGAAATCAAGTCACTCGCAACAAGCTTCATAG
CGGTATCAGCGATAATTATGCCGTTTTGTGCATTTACACATTCGTCGTATTTCACACTCCGCTCAGGCGGCAAGACACTG
GTCACATTTCTGTTTGACTCCGTATTTACGTGGGTGATAGTGGTGCCGGTGGCATTTGTGCTCGCCAAATACACAGCAAT
TGGCATAGTAGCAGTGTACTTCCTTGTGCAGGCCACAGAGCTGATAAAGGTAGTCATCGGATACTTCATGGTGAAAAGCG
ACGTGTGGCTCGTGCAGATGGTATAG

Upstream 100 bases:

>100_bases
TTAAGGAAAAACACATAAAATATTTGAAAAATAAAGTCTGACGTAGTAGAATAGTAACATTGCACGAAAGGACCATGGAG
AAATCGAAAGGGGGACAAAT

Downstream 100 bases:

>100_bases
GAATGTAAGTCATTATCTTGCGGAAAAGTAAAATAAAAGTTATACTGTAGCAAAAGTCAGCGTAACAGTTCTAACCCAGA
ATGAAACGGAGCATAAAATG

Product: hypothetical protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 461; Mature: 461

Protein sequence:

>461_residues
MHKFRQKYIGDKAFYKRYLMLAIPMIIQNAITNLVSFLDNIMVGQLGTEQMSGVAIVNQLIFVYNLAVFGAVSAASIFGA
QYFGKGNHKGHMYSFRFKLYAALLVTAIAMTLFITNGTGFISLYLTDTAGNGATEVALAYGKEYLEIVMIGLIPFAVTQA
YATNIKETGQTFVPMVASFAAVGSNAVLDFLLIFGIGPIPKLGVAGAAIATVMSRYIETIIVVLWAHKNRDKNRYLEGAY
RGIGMPFGEFKTIFIKGLPLMLNELLWAAGMTTVTQCYSVRGLSVIAGLNIATTITNLFNIVFIQLGACISIVVGQYLGA
GELEKAKDADNKMIVFSVFCCSVMAAVMLLVGGFFPQIYNTTDEIKSLATSFIAVSAIIMPFCAFTHSSYFTLRSGGKTL
VTFLFDSVFTWVIVVPVAFVLAKYTAIGIVAVYFLVQATELIKVVIGYFMVKSDVWLVQMV

Sequences:

>Translated_461_residues
MHKFRQKYIGDKAFYKRYLMLAIPMIIQNAITNLVSFLDNIMVGQLGTEQMSGVAIVNQLIFVYNLAVFGAVSAASIFGA
QYFGKGNHKGHMYSFRFKLYAALLVTAIAMTLFITNGTGFISLYLTDTAGNGATEVALAYGKEYLEIVMIGLIPFAVTQA
YATNIKETGQTFVPMVASFAAVGSNAVLDFLLIFGIGPIPKLGVAGAAIATVMSRYIETIIVVLWAHKNRDKNRYLEGAY
RGIGMPFGEFKTIFIKGLPLMLNELLWAAGMTTVTQCYSVRGLSVIAGLNIATTITNLFNIVFIQLGACISIVVGQYLGA
GELEKAKDADNKMIVFSVFCCSVMAAVMLLVGGFFPQIYNTTDEIKSLATSFIAVSAIIMPFCAFTHSSYFTLRSGGKTL
VTFLFDSVFTWVIVVPVAFVLAKYTAIGIVAVYFLVQATELIKVVIGYFMVKSDVWLVQMV
>Mature_461_residues
MHKFRQKYIGDKAFYKRYLMLAIPMIIQNAITNLVSFLDNIMVGQLGTEQMSGVAIVNQLIFVYNLAVFGAVSAASIFGA
QYFGKGNHKGHMYSFRFKLYAALLVTAIAMTLFITNGTGFISLYLTDTAGNGATEVALAYGKEYLEIVMIGLIPFAVTQA
YATNIKETGQTFVPMVASFAAVGSNAVLDFLLIFGIGPIPKLGVAGAAIATVMSRYIETIIVVLWAHKNRDKNRYLEGAY
RGIGMPFGEFKTIFIKGLPLMLNELLWAAGMTTVTQCYSVRGLSVIAGLNIATTITNLFNIVFIQLGACISIVVGQYLGA
GELEKAKDADNKMIVFSVFCCSVMAAVMLLVGGFFPQIYNTTDEIKSLATSFIAVSAIIMPFCAFTHSSYFTLRSGGKTL
VTFLFDSVFTWVIVVPVAFVLAKYTAIGIVAVYFLVQATELIKVVIGYFMVKSDVWLVQMV

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=460, Percent_Identity=23.4782608695652, Blast_Score=99, Evalue=7e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 50272; Mature: 50272

Theoretical pI: Translated: 9.22; Mature: 9.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]