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The map label for this gene is rsmH1

Identifier: 238922879

GI number: 238922879

Start: 426052

End: 427101

Strand: Direct

Name: rsmH1

Synonym: EUBREC_0467

Alternate gene names: 238922879

Gene position: 426052-427101 (Clockwise)

Preceding gene: 238922878

Following gene: 238922881

Centisome position: 12.35

GC content: 46.29

Gene sequence:

>1050_bases
ATGAGCGAAGAAAAACAGCACAAGCGCCGCGTGCATTATAGCGGAAAATATCCCAAAAAATTTGAGGAAAAATACAAGGA
ATTAAATCCGGAGAAATACAAGGATACAATTGAGCATGTCATCAGCAAGGGAAATACCCCTGCGGGCATGCACATATCCA
TAATGGTAAAAGAAATCATAGATTTTCTGGACATAAAGCCGGGACAGACAGGCTTTGATGCCACACTCGGATACGGTGGC
CACACAAGGGCAATGCTTGAAAAGCTTGAAGGACAGGGACATATGTTTGCTACAGATGTTGACCCAATCGAGTCTGAAAA
GACAAAAAAGCGTCTCGCTGAAGCAGGCTTTGGAGAGGATATTCTCACCATAAAGCTTCAAAACTTCTGCACAATAGATG
AGATTGCAAAGGAAGTAGGAGGCTTTGATTTCATACTTGCCGATCTGGGAGTTTCATCAATGCAGATAGATAATCCTGAG
CGTGGTTTTTCGTTTAAGGTGGATGGACCGCTGGATCTGCGTCTTAATCCAAATGCCGGTATCAGTGCGGCAGAGCGGCT
TGATAATATATCCCGTGAGGAACTTTCAGGTATGCTCTATGAGAACTCAGATGAGCCGTATTGCGAGGAGCTTGCAAAGG
CTATCACAGACGAGATCAGGAAGGGGAACCGCATAGGTACGACCACAAAGCTTCGTCACATTATAGAGCAGACACTCGAT
TTTCTGCCTGAAAAGGATAAGAAGGACATAATCAAAAAGACCTGTCAGCGCACATTCCAGGCGCTCCGCATAGACGTAAA
CCATGAGTTTGAGGTGCTATATGAGTTTATGGAAAAGCTTCCGGGAGCATTAAAGCCCGGAGGAAGAGCTGCCATCCTTA
CCTTCCATTCAGGAGAGGACAAGCTGGTCAAAAAGGCACTCAAGGCAGGATATAAAGCAGGAATATACAGCGACTATTCC
AAGGATGTGATTCGTCCATCAGCACAGGAATGTGCTCAGAACGGACGTGCCAGGTCCACGAAGATGCGCTGGGCGGTCCG
TGCGGAATAG

Upstream 100 bases:

>100_bases
TAGGAATGTAAGTCATTATCTTGCGGAAAAGTAAAATAAAAGTTATACTGTAGCAAAAGTCAGCGTAACAGTTCTAACCC
AGAATGAAACGGAGCATAAA

Downstream 100 bases:

>100_bases
AAAAGAATAAAAATAGTTCTAAAAACCTATTGCTTTATTGAGAAAAATAGTCTACTATGAACGTGTTATATGACTGACGG
ATAAGTGGAATAACCACATG

Product: methyltransferase

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase 1; rRNA (cytosine-N(4)-)-methyltransferase RsmH 1

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MSEEKQHKRRVHYSGKYPKKFEEKYKELNPEKYKDTIEHVISKGNTPAGMHISIMVKEIIDFLDIKPGQTGFDATLGYGG
HTRAMLEKLEGQGHMFATDVDPIESEKTKKRLAEAGFGEDILTIKLQNFCTIDEIAKEVGGFDFILADLGVSSMQIDNPE
RGFSFKVDGPLDLRLNPNAGISAAERLDNISREELSGMLYENSDEPYCEELAKAITDEIRKGNRIGTTTKLRHIIEQTLD
FLPEKDKKDIIKKTCQRTFQALRIDVNHEFEVLYEFMEKLPGALKPGGRAAILTFHSGEDKLVKKALKAGYKAGIYSDYS
KDVIRPSAQECAQNGRARSTKMRWAVRAE

Sequences:

>Translated_349_residues
MSEEKQHKRRVHYSGKYPKKFEEKYKELNPEKYKDTIEHVISKGNTPAGMHISIMVKEIIDFLDIKPGQTGFDATLGYGG
HTRAMLEKLEGQGHMFATDVDPIESEKTKKRLAEAGFGEDILTIKLQNFCTIDEIAKEVGGFDFILADLGVSSMQIDNPE
RGFSFKVDGPLDLRLNPNAGISAAERLDNISREELSGMLYENSDEPYCEELAKAITDEIRKGNRIGTTTKLRHIIEQTLD
FLPEKDKKDIIKKTCQRTFQALRIDVNHEFEVLYEFMEKLPGALKPGGRAAILTFHSGEDKLVKKALKAGYKAGIYSDYS
KDVIRPSAQECAQNGRARSTKMRWAVRAE
>Mature_348_residues
SEEKQHKRRVHYSGKYPKKFEEKYKELNPEKYKDTIEHVISKGNTPAGMHISIMVKEIIDFLDIKPGQTGFDATLGYGGH
TRAMLEKLEGQGHMFATDVDPIESEKTKKRLAEAGFGEDILTIKLQNFCTIDEIAKEVGGFDFILADLGVSSMQIDNPER
GFSFKVDGPLDLRLNPNAGISAAERLDNISREELSGMLYENSDEPYCEELAKAITDEIRKGNRIGTTTKLRHIIEQTLDF
LPEKDKKDIIKKTCQRTFQALRIDVNHEFEVLYEFMEKLPGALKPGGRAAILTFHSGEDKLVKKALKAGYKAGIYSDYSK
DVIRPSAQECAQNGRARSTKMRWAVRAE

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=388, Percent_Identity=30.4123711340206, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI165377202, Length=240, Percent_Identity=32.0833333333333, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1786270, Length=317, Percent_Identity=34.384858044164, Blast_Score=162, Evalue=2e-41,
Organism=Drosophila melanogaster, GI62472493, Length=354, Percent_Identity=32.2033898305085, Blast_Score=149, Evalue=3e-36,
Organism=Drosophila melanogaster, GI28571637, Length=354, Percent_Identity=32.2033898305085, Blast_Score=149, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH1_EUBR3 (C4ZBW8)

Other databases:

- EMBL:   CP001107
- RefSeq:   YP_002936392.1
- ProteinModelPortal:   C4ZBW8
- GeneID:   7966635
- GenomeReviews:   CP001107_GR
- KEGG:   ere:EUBREC_0467
- ProtClustDB:   CLSK976804
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 39427; Mature: 39296

Theoretical pI: Translated: 7.01; Mature: 7.01

Prosite motif: NA

Important sites: BINDING 99-99 BINDING 129-129 BINDING 148-148 BINDING 155-155

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEKQHKRRVHYSGKYPKKFEEKYKELNPEKYKDTIEHVISKGNTPAGMHISIMVKEII
CCCHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
DFLDIKPGQTGFDATLGYGGHTRAMLEKLEGQGHMFATDVDPIESEKTKKRLAEAGFGED
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHCCCCCC
ILTIKLQNFCTIDEIAKEVGGFDFILADLGVSSMQIDNPERGFSFKVDGPLDLRLNPNAG
EEEEEECCCCCHHHHHHHHCCCEEHHHHCCCCCEECCCCCCCCEEEECCCEEEEECCCCC
ISAAERLDNISREELSGMLYENSDEPYCEELAKAITDEIRKGNRIGTTTKLRHIIEQTLD
CHHHHHHHCCCHHHHHCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
FLPEKDKKDIIKKTCQRTFQALRIDVNHEFEVLYEFMEKLPGALKPGGRAAILTFHSGED
HCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCH
KLVKKALKAGYKAGIYSDYSKDVIRPSAQECAQNGRARSTKMRWAVRAE
HHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHCCCCCCHHEEEEEECC
>Mature Secondary Structure 
SEEKQHKRRVHYSGKYPKKFEEKYKELNPEKYKDTIEHVISKGNTPAGMHISIMVKEII
CCHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
DFLDIKPGQTGFDATLGYGGHTRAMLEKLEGQGHMFATDVDPIESEKTKKRLAEAGFGED
HHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCEEECCCCCCCHHHHHHHHHHCCCCCC
ILTIKLQNFCTIDEIAKEVGGFDFILADLGVSSMQIDNPERGFSFKVDGPLDLRLNPNAG
EEEEEECCCCCHHHHHHHHCCCEEHHHHCCCCCEECCCCCCCCEEEECCCEEEEECCCCC
ISAAERLDNISREELSGMLYENSDEPYCEELAKAITDEIRKGNRIGTTTKLRHIIEQTLD
CHHHHHHHCCCHHHHHCHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
FLPEKDKKDIIKKTCQRTFQALRIDVNHEFEVLYEFMEKLPGALKPGGRAAILTFHSGED
HCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCH
KLVKKALKAGYKAGIYSDYSKDVIRPSAQECAQNGRARSTKMRWAVRAE
HHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHCCCCCCHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA