Click here to switch to the map view.

The map label for this gene is yclJ [H]

Identifier: 238922876

GI number: 238922876

Start: 421608

End: 422297

Strand: Direct

Name: yclJ [H]

Synonym: EUBREC_0464

Alternate gene names: 238922876

Gene position: 421608-422297 (Clockwise)

Preceding gene: 238922875

Following gene: 238922877

Centisome position: 12.22

GC content: 45.51

Gene sequence:

>690_bases
ATGAGCAGAATTTTGATAGTAGAGGACGAGGTTGCAATTGCTGATCTTGAGAAGGATTACCTGGAGCTGAGCGGCTTTGA
GGTAGAGGTGGAGAATGATGGCACAAGCGGTCTCGCAAGGGCTTTGGCGGAGGATTTTGATCTGTTTATTTTGGATCTTA
TGCTGCCGGGCATTGATGGATTTGAGATTTGTAAGCGGATTCGTGAGAAAAAGAACACACCGATACTCATGGTTTCAGCA
AAGAAGGATGATATCGACAAGATAAGAGGACTCGGACTCGGCGCAGATGATTATGTCACAAAGCCGTTTTCACCATCAGA
GCTTGTTGCCAGGGTAAAGGCTCATCTGGCCAGATATGAGCGCCTGATCGGAAGCGCCACACCTGAAAATGACATCGTTG
AAATTCGTGGCATCAAGATTGACAAAACAGCCCGCCGTGTTTGGGTAAACGGAGAGGAAAAGCAGTTTACCACAAAGGAA
TTTGACCTGCTCACATTCCTTGCGGAAAATCCAAACCATGTATTTACCAAGGAGGAGCTCTTCAAGGAAATCTGGAATAT
GGATTCGGTCGGAGATATCGCGACAGTCACTGTACATATCAAGAAGATTCGTGAAAAAATCGAGATGAACACTGCAAAGC
CACAGTATATTGAGACTATTTGGGGCGTGGGATACAGATTTAAGCTGTAG

Upstream 100 bases:

>100_bases
AGAAAATTTAGACAGAAGTTACCGGATATATGATATAATTAAGTCATGGGACTGACATTGAGTCGGTTTCCATGGCTTTT
TATTTTCAGGAGGAACGGAT

Downstream 100 bases:

>100_bases
TGATTTTAAAAAAATATAGTAGATATTGTAGTATTAATAGGACATATCAAATTCAAATGCGAAAGGATATGTCCTTGTTG
TATATATAAAGTGGCTTATT

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MSRILIVEDEVAIADLEKDYLELSGFEVEVENDGTSGLARALAEDFDLFILDLMLPGIDGFEICKRIREKKNTPILMVSA
KKDDIDKIRGLGLGADDYVTKPFSPSELVARVKAHLARYERLIGSATPENDIVEIRGIKIDKTARRVWVNGEEKQFTTKE
FDLLTFLAENPNHVFTKEELFKEIWNMDSVGDIATVTVHIKKIREKIEMNTAKPQYIETIWGVGYRFKL

Sequences:

>Translated_229_residues
MSRILIVEDEVAIADLEKDYLELSGFEVEVENDGTSGLARALAEDFDLFILDLMLPGIDGFEICKRIREKKNTPILMVSA
KKDDIDKIRGLGLGADDYVTKPFSPSELVARVKAHLARYERLIGSATPENDIVEIRGIKIDKTARRVWVNGEEKQFTTKE
FDLLTFLAENPNHVFTKEELFKEIWNMDSVGDIATVTVHIKKIREKIEMNTAKPQYIETIWGVGYRFKL
>Mature_228_residues
SRILIVEDEVAIADLEKDYLELSGFEVEVENDGTSGLARALAEDFDLFILDLMLPGIDGFEICKRIREKKNTPILMVSAK
KDDIDKIRGLGLGADDYVTKPFSPSELVARVKAHLARYERLIGSATPENDIVEIRGIKIDKTARRVWVNGEEKQFTTKEF
DLLTFLAENPNHVFTKEELFKEIWNMDSVGDIATVTVHIKKIREKIEMNTAKPQYIETIWGVGYRFKL

Specific function: Could be member of the two-component regulatory system yclK/yclJ [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=227, Percent_Identity=35.2422907488987, Blast_Score=153, Evalue=9e-39,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=36.5217391304348, Blast_Score=151, Evalue=4e-38,
Organism=Escherichia coli, GI1788394, Length=228, Percent_Identity=37.719298245614, Blast_Score=150, Evalue=6e-38,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=36, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1786911, Length=229, Percent_Identity=34.9344978165939, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=34.2105263157895, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1790863, Length=229, Percent_Identity=34.9344978165939, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=33.6283185840708, Blast_Score=124, Evalue=5e-30,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=34.3347639484979, Blast_Score=113, Evalue=9e-27,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=32.5892857142857, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=29.9559471365639, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1787229, Length=226, Percent_Identity=31.4159292035398, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=32.0512820512821, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787375, Length=228, Percent_Identity=28.5087719298246, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=32.1100917431193, Blast_Score=61, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26123; Mature: 25992

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRILIVEDEVAIADLEKDYLELSGFEVEVENDGTSGLARALAEDFDLFILDLMLPGIDG
CCEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
FEICKRIREKKNTPILMVSAKKDDIDKIRGLGLGADDYVTKPFSPSELVARVKAHLARYE
HHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHH
RLIGSATPENDIVEIRGIKIDKTARRVWVNGEEKQFTTKEFDLLTFLAENPNHVFTKEEL
HHHCCCCCCCCEEEEECEEEECCHHEEEECCCCCCCCHHHHHHHHEEECCCCCCCCHHHH
FKEIWNMDSVGDIATVTVHIKKIREKIEMNTAKPQYIETIWGVGYRFKL
HHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECC
>Mature Secondary Structure 
SRILIVEDEVAIADLEKDYLELSGFEVEVENDGTSGLARALAEDFDLFILDLMLPGIDG
CEEEEEECCHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCH
FEICKRIREKKNTPILMVSAKKDDIDKIRGLGLGADDYVTKPFSPSELVARVKAHLARYE
HHHHHHHHHCCCCCEEEEECCCCCHHHHHCCCCCCHHCCCCCCCHHHHHHHHHHHHHHHH
RLIGSATPENDIVEIRGIKIDKTARRVWVNGEEKQFTTKEFDLLTFLAENPNHVFTKEEL
HHHCCCCCCCCEEEEECEEEECCHHEEEECCCCCCCCHHHHHHHHEEECCCCCCCCHHHH
FKEIWNMDSVGDIATVTVHIKKIREKIEMNTAKPQYIETIWGVGYRFKL
HHHHHCCCCCCCEEHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]