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The map label for this gene is trpS [H]

Identifier: 238922826

GI number: 238922826

Start: 379823

End: 380911

Strand: Direct

Name: trpS [H]

Synonym: EUBREC_0414

Alternate gene names: 238922826

Gene position: 379823-380911 (Clockwise)

Preceding gene: 238922825

Following gene: 238922827

Centisome position: 11.01

GC content: 44.35

Gene sequence:

>1089_bases
ATGGAAAAAATTATTTTAACAGGAGACAGACCAACAGGAAGACTCCATATAGGACATTACGTGGGCTCCCTTCGCAGAAG
AGTTGAGCTTCAGAATTCAGGAGAGTATGACAAAATATTTATCATGATTGCCGATGCACAGGCACTCACAGACAATTTTG
ACAACCCTGAGAAAATCAGACAGAATATCATAGAGGTAGCACTTGATTACCTCTCAGCAGGACTCGACCCGGCCAAGTCT
ACACTGTTTGTGCAGTCACAGATACCGGAGCTTACTGAGCTTACATTTTTCTACTCAAATCTCGTTACAGTATCGAGACT
TCAGAGAAACCCTACAGTAAAGAACGAGATTAAGCTAAGAAATTTCGAGGCAAGTATACCGGTTGGCTTTTTCAATTATC
CAATCAGTCAGGCAGCAGATATCACTGCCTTCAAGGCTACAACTGTTCCGGTTGGAGAGGACCAGCTCCCAATGATAGAG
CAGACCAGGGAGATTGTCAGAAAGTTTAATTCTATCTATGATGAGGTGCTCGTTGAGCCGGATGTGCTTTTACCTGAGAA
TGAGGCATGCTGCAGACTTCCGGGTACAGACGGTGGACAGAAGATGAGCAAATCATTAGGCAACTGTATCTATCTGGCAG
ATACAGAGGCAGATGTAAAGAAGAAAATCATGAGCATGTATACAGATCCGACACATATCCAGATTTCAGATCCGGGACAT
GTGGAGGGCAATACAGTATTCACATATCTTGATGCTTTCTCTAAGCCGGGACATTTTGAGGAGTATCTGCCGGAGTATGC
TAACCTTCAGGAGCTTAAGGACCACTATACAAGAGGCGGTCTTGGTGATGTGAAGATTAAGAAATTCCTCAACAACATCA
TGCAGGAGGAACTTTCACCTATCCGCGCAAGAAGAGCAGAGTATGAGAAGGATATTCCGGCTGTATATGAGATACTAAGG
AAGGGCAGCGAGACAGCAAGAGAGGCTGCAGCACAGACAATGGCAGAGGTCAAGCGCGCCATGAGGATAAATTACTTTGA
GGATGCAGAGCTTATAAAGAGCCAGAGTCAGAAATATGCTGAGAAGTAA

Upstream 100 bases:

>100_bases
GTTATAATAAAGAAAGCTGGCGATTGCTAAGACAGACGGTTTGGCGAATAAACCTACATTGCAATCGTAGTAATAGAACT
AAAGCAGAGGAATAATAGAG

Downstream 100 bases:

>100_bases
TATCTTTTATTTCAAAGACAATACGTTAGTGATGTCAAAATATTTTGTGGCATTATGTGTGTCATAAAAGCCACGGGGAG
GCACCATGGTCAAGTTTTAC

Product: tryptophanyl-tRNA synthetase II

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MEKIILTGDRPTGRLHIGHYVGSLRRRVELQNSGEYDKIFIMIADAQALTDNFDNPEKIRQNIIEVALDYLSAGLDPAKS
TLFVQSQIPELTELTFFYSNLVTVSRLQRNPTVKNEIKLRNFEASIPVGFFNYPISQAADITAFKATTVPVGEDQLPMIE
QTREIVRKFNSIYDEVLVEPDVLLPENEACCRLPGTDGGQKMSKSLGNCIYLADTEADVKKKIMSMYTDPTHIQISDPGH
VEGNTVFTYLDAFSKPGHFEEYLPEYANLQELKDHYTRGGLGDVKIKKFLNNIMQEELSPIRARRAEYEKDIPAVYEILR
KGSETAREAAAQTMAEVKRAMRINYFEDAELIKSQSQKYAEK

Sequences:

>Translated_362_residues
MEKIILTGDRPTGRLHIGHYVGSLRRRVELQNSGEYDKIFIMIADAQALTDNFDNPEKIRQNIIEVALDYLSAGLDPAKS
TLFVQSQIPELTELTFFYSNLVTVSRLQRNPTVKNEIKLRNFEASIPVGFFNYPISQAADITAFKATTVPVGEDQLPMIE
QTREIVRKFNSIYDEVLVEPDVLLPENEACCRLPGTDGGQKMSKSLGNCIYLADTEADVKKKIMSMYTDPTHIQISDPGH
VEGNTVFTYLDAFSKPGHFEEYLPEYANLQELKDHYTRGGLGDVKIKKFLNNIMQEELSPIRARRAEYEKDIPAVYEILR
KGSETAREAAAQTMAEVKRAMRINYFEDAELIKSQSQKYAEK
>Mature_362_residues
MEKIILTGDRPTGRLHIGHYVGSLRRRVELQNSGEYDKIFIMIADAQALTDNFDNPEKIRQNIIEVALDYLSAGLDPAKS
TLFVQSQIPELTELTFFYSNLVTVSRLQRNPTVKNEIKLRNFEASIPVGFFNYPISQAADITAFKATTVPVGEDQLPMIE
QTREIVRKFNSIYDEVLVEPDVLLPENEACCRLPGTDGGQKMSKSLGNCIYLADTEADVKKKIMSMYTDPTHIQISDPGH
VEGNTVFTYLDAFSKPGHFEEYLPEYANLQELKDHYTRGGLGDVKIKKFLNNIMQEELSPIRARRAEYEKDIPAVYEILR
KGSETAREAAAQTMAEVKRAMRINYFEDAELIKSQSQKYAEK

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=341, Percent_Identity=29.9120234604106, Blast_Score=140, Evalue=2e-33,
Organism=Homo sapiens, GI41352700, Length=183, Percent_Identity=37.1584699453552, Blast_Score=125, Evalue=4e-29,
Organism=Escherichia coli, GI1789786, Length=345, Percent_Identity=28.9855072463768, Blast_Score=131, Evalue=8e-32,
Organism=Caenorhabditis elegans, GI71982800, Length=348, Percent_Identity=29.8850574712644, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71982793, Length=348, Percent_Identity=29.8850574712644, Blast_Score=131, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6320474, Length=364, Percent_Identity=28.5714285714286, Blast_Score=125, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24666151, Length=340, Percent_Identity=31.7647058823529, Blast_Score=158, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 41092; Mature: 41092

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKIILTGDRPTGRLHIGHYVGSLRRRVELQNSGEYDKIFIMIADAQALTDNFDNPEKIR
CCCEEEECCCCCCEEEHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHCCCCCHHHHH
QNIIEVALDYLSAGLDPAKSTLFVQSQIPELTELTFFYSNLVTVSRLQRNPTVKNEIKLR
HHHHHHHHHHHHCCCCCHHHEEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEE
NFEASIPVGFFNYPISQAADITAFKATTVPVGEDQLPMIEQTREIVRKFNSIYDEVLVEP
CCCCCCCCCCCCCCCHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
DVLLPENEACCRLPGTDGGQKMSKSLGNCIYLADTEADVKKKIMSMYTDPTHIQISDPGH
CCCCCCCCCCEECCCCCCHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCCEEEECCCCC
VEGNTVFTYLDAFSKPGHFEEYLPEYANLQELKDHYTRGGLGDVKIKKFLNNIMQEELSP
CCCCEEEEEEHHCCCCCCHHHHCHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IRARRAEYEKDIPAVYEILRKGSETAREAAAQTMAEVKRAMRINYFEDAELIKSQSQKYA
HHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
EK
CC
>Mature Secondary Structure
MEKIILTGDRPTGRLHIGHYVGSLRRRVELQNSGEYDKIFIMIADAQALTDNFDNPEKIR
CCCEEEECCCCCCEEEHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHCCCCCHHHHH
QNIIEVALDYLSAGLDPAKSTLFVQSQIPELTELTFFYSNLVTVSRLQRNPTVKNEIKLR
HHHHHHHHHHHHCCCCCHHHEEEEHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHEEEE
NFEASIPVGFFNYPISQAADITAFKATTVPVGEDQLPMIEQTREIVRKFNSIYDEVLVEP
CCCCCCCCCCCCCCCHHCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
DVLLPENEACCRLPGTDGGQKMSKSLGNCIYLADTEADVKKKIMSMYTDPTHIQISDPGH
CCCCCCCCCCEECCCCCCHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCCEEEECCCCC
VEGNTVFTYLDAFSKPGHFEEYLPEYANLQELKDHYTRGGLGDVKIKKFLNNIMQEELSP
CCCCEEEEEEHHCCCCCCHHHHCHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
IRARRAEYEKDIPAVYEILRKGSETAREAAAQTMAEVKRAMRINYFEDAELIKSQSQKYA
HHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
EK
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA