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The map label for this gene is udp [H]

Identifier: 238922717

GI number: 238922717

Start: 273941

End: 274723

Strand: Direct

Name: udp [H]

Synonym: EUBREC_0292

Alternate gene names: 238922717

Gene position: 273941-274723 (Clockwise)

Preceding gene: 238922716

Following gene: 238922718

Centisome position: 7.94

GC content: 51.47

Gene sequence:

>783_bases
ATGAAAAATTATTCAAAGGATCCTGACAGACAGTATCATATCCAGGTCGCAAAGGGAGAGGTCGGCAGGTATGTTATCAT
GCCGGGAGACCCGAAGAGATGTGTTAAAATAGCTCAGTACCTTGACAATCCGGTCTTGATAGCTGACAACAGGGAGTTTA
TCACATACACCGGCACATTGGATGGAGTGAAGGTCAGTGTGACATCGACAGGCATTGGCGGACCATCCGCATCTATAGCG
ATGGAGGAGCTGTACAGATGCGGTGCAGATACCTTCGTGAGGATCGGAACCTGCGGAGGCATGCAGACAGATGTGAAAAG
CGGTGACATCGTGATTGCGACAGGCGCCATCCGCATGGAGGGCACATCAAAGGAGTATGCGCCGATAGAGTTTCCGGCTG
TGGCAGATTTAGATGTCACAAACGCGCTTGTTGCGGCAGCAAAGCAGAAAAACTTTACGCATCACACAGGCGTGGTGCAG
TGCAAGGATGCATTTTACGGACAGCACGAGCCCGAAAAAATGCCGGCAGGCTACGAGCTTATCAATAAATGGAATGCATG
GAGGATGCTTGGCTGTCTTGCGTCAGAGATGGAGTCAGCCGCGCTTTTTGTCGTTGCGGCAAAGCTTGGAGTCAGGGCAG
GTTCATGCTTCCTTGTGGTCGCAAATCAGGAGAGGGAAAAGCTCGGGCTTGAGAATCCTGTGGTACGCGATACTGACATG
GCGGTTCAGGTGGCGGTTTCGGCAGTGCGAAATCTCATTAGTGAGGATTGCGCCGGAGAATAA

Upstream 100 bases:

>100_bases
TTTTTATAGATTGTAAGAAAATGTCCTTTCCTCTGCACAAAACCACAGAAATTGTGTATAATTAAAGCTAACAAAAGAAA
ACTGTGGGAGGTGGCATTAC

Downstream 100 bases:

>100_bases
GTCAGACATAAAACACAGAAACGGAGAACAGACATTGGATATAAATGAAATTTTAAAACACGTTGACCATACACTTTTAT
CCCCACAGGCTACATGGGAC

Product: uridine phosphorylase

Products: NA

Alternate protein names: UPase; UrdPase [H]

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MKNYSKDPDRQYHIQVAKGEVGRYVIMPGDPKRCVKIAQYLDNPVLIADNREFITYTGTLDGVKVSVTSTGIGGPSASIA
MEELYRCGADTFVRIGTCGGMQTDVKSGDIVIATGAIRMEGTSKEYAPIEFPAVADLDVTNALVAAAKQKNFTHHTGVVQ
CKDAFYGQHEPEKMPAGYELINKWNAWRMLGCLASEMESAALFVVAAKLGVRAGSCFLVVANQEREKLGLENPVVRDTDM
AVQVAVSAVRNLISEDCAGE

Sequences:

>Translated_260_residues
MKNYSKDPDRQYHIQVAKGEVGRYVIMPGDPKRCVKIAQYLDNPVLIADNREFITYTGTLDGVKVSVTSTGIGGPSASIA
MEELYRCGADTFVRIGTCGGMQTDVKSGDIVIATGAIRMEGTSKEYAPIEFPAVADLDVTNALVAAAKQKNFTHHTGVVQ
CKDAFYGQHEPEKMPAGYELINKWNAWRMLGCLASEMESAALFVVAAKLGVRAGSCFLVVANQEREKLGLENPVVRDTDM
AVQVAVSAVRNLISEDCAGE
>Mature_260_residues
MKNYSKDPDRQYHIQVAKGEVGRYVIMPGDPKRCVKIAQYLDNPVLIADNREFITYTGTLDGVKVSVTSTGIGGPSASIA
MEELYRCGADTFVRIGTCGGMQTDVKSGDIVIATGAIRMEGTSKEYAPIEFPAVADLDVTNALVAAAKQKNFTHHTGVVQ
CKDAFYGQHEPEKMPAGYELINKWNAWRMLGCLASEMESAALFVVAAKLGVRAGSCFLVVANQEREKLGLENPVVRDTDM
AVQVAVSAVRNLISEDCAGE

Specific function: Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synth

COG id: COG2820

COG function: function code F; Uridine phosphorylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790265, Length=247, Percent_Identity=40.080971659919, Blast_Score=185, Evalue=3e-48,
Organism=Escherichia coli, GI1790844, Length=206, Percent_Identity=33.0097087378641, Blast_Score=97, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845
- InterPro:   IPR010058 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.3 [H]

Molecular weight: Translated: 28116; Mature: 28116

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYSKDPDRQYHIQVAKGEVGRYVIMPGDPKRCVKIAQYLDNPVLIADNREFITYTGTL
CCCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCEEEECCCEEEEEECCC
DGVKVSVTSTGIGGPSASIAMEELYRCGADTFVRIGTCGGMQTDVKSGDIVIATGAIRME
CCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEECEEEEC
GTSKEYAPIEFPAVADLDVTNALVAAAKQKNFTHHTGVVQCKDAFYGQHEPEKMPAGYEL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECHHHCCCCCCCCCCCCHHH
INKWNAWRMLGCLASEMESAALFVVAAKLGVRAGSCFLVVANQEREKLGLENPVVRDTDM
HHHCCHHHHHHHHHHHHHHHEEEEEEEHHCCCCCCEEEEEECCCHHHCCCCCCCCCCCHH
AVQVAVSAVRNLISEDCAGE
HHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKNYSKDPDRQYHIQVAKGEVGRYVIMPGDPKRCVKIAQYLDNPVLIADNREFITYTGTL
CCCCCCCCCCEEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCEEEECCCEEEEEECCC
DGVKVSVTSTGIGGPSASIAMEELYRCGADTFVRIGTCGGMQTDVKSGDIVIATGAIRME
CCEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEEEECEEEEC
GTSKEYAPIEFPAVADLDVTNALVAAAKQKNFTHHTGVVQCKDAFYGQHEPEKMPAGYEL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEEECHHHCCCCCCCCCCCCHHH
INKWNAWRMLGCLASEMESAALFVVAAKLGVRAGSCFLVVANQEREKLGLENPVVRDTDM
HHHCCHHHHHHHHHHHHHHHEEEEEEEHHCCCCCCEEEEEECCCHHHCCCCCCCCCCCHH
AVQVAVSAVRNLISEDCAGE
HHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]