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The map label for this gene is cytR [C]

Identifier: 238922674

GI number: 238922674

Start: 231464

End: 232468

Strand: Direct

Name: cytR [C]

Synonym: EUBREC_0249

Alternate gene names: 238922674

Gene position: 231464-232468 (Clockwise)

Preceding gene: 238922673

Following gene: 238922675

Centisome position: 6.71

GC content: 44.08

Gene sequence:

>1005_bases
ATGACAATTGTAGATATAGCAAAAGAATCGGGATACTCAGTAACAACTGTATCCCGAGTTTTAAATAACAGGCAGGATGT
TTCTCCTGCAGCAAAAGAAACCATAATGAAAATAGTTGAGGCACACAACTTTGTGCCAAATACCAATGCAAAGAGGCTCA
AGCAGACCATTTCCAGAAATATTTATCTGTTGGTAAAGGGTACCTCTAATATGCTGTTTGCAAACGTAGTCGAGGAAATC
CAGTCGATAATAGACAGAACAGACTACTCTTTGAGCATCACATATCTGGATGAGGACAGTAATCTAAGCAGTGTGACAGA
CCGCATATGCAGGGAGCGAAAGCCGCTTGGCATCATATTCCTCGGAGGCAGCAGGGAGGATTTCTCGGAGGATACATCTT
CGTTTAAGGTGCCGTGTGTTATCGTGACCACATCGGCAGAAAACTGGAGCATGGAGGAGCTGTCATCTGTTTCCATTGAT
GATGAGAAGGCAGGGGAAACAATCGTCGACTATCTCATCGAGCATGGACATACAAAGATAGCAGAGATTGGAGCCAATCT
GGAGCTTTCACAGACAGCTCGTCTGCGACATAACGGATATCTCAACAGCTTAAAAAAGCATGGAATCACACCTGATGAGC
GTTACTATGAGAGAGCGCGATTCTCATATGACAGCGCATATCGTGCGATGAAAAAGCTTTTGGAAAAGGATATAGAAATC
ACCGCAGTCTATGCGATTTCCGATGTCATGGCAATCGGTGCCTTAAGGGCAATACTTGATAAGGGACTCAGGGTGCCGGA
AGATATATCTATCACAGGCTTTGATGGTTCGACACTTGCAGAGTACTACAATCCCAAGATTGTATCTATCAGACAGCCGC
ACAAGGATATGGCGGCACGCAGCGTGGAGCTTCTTTTTAACATGATAGATTTGCATAAAGGCTCATGTCATGAGATAATA
CCATTTGAGCTGACAGAGGGCGAGAGTGTTGCTAGAATTGATTAA

Upstream 100 bases:

>100_bases
CAGGTTTTGTAGTTGTGGATATATGATATAACGAGTGAAATAAATTATATCACATGGATATAATGTAAAAGGACGTATCG
CTGTCCGGACGGGGAAAACA

Downstream 100 bases:

>100_bases
AGACTATATAATATCAGCTTGTTACATTCCGGACATACAATAAACGAGGAGGAATCGCGCATGGAAGTGAATAATAAGAT
GAAGCACACCATAAAGGTCG

Product: catabolite control protein A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MTIVDIAKESGYSVTTVSRVLNNRQDVSPAAKETIMKIVEAHNFVPNTNAKRLKQTISRNIYLLVKGTSNMLFANVVEEI
QSIIDRTDYSLSITYLDEDSNLSSVTDRICRERKPLGIIFLGGSREDFSEDTSSFKVPCVIVTTSAENWSMEELSSVSID
DEKAGETIVDYLIEHGHTKIAEIGANLELSQTARLRHNGYLNSLKKHGITPDERYYERARFSYDSAYRAMKKLLEKDIEI
TAVYAISDVMAIGALRAILDKGLRVPEDISITGFDGSTLAEYYNPKIVSIRQPHKDMAARSVELLFNMIDLHKGSCHEII
PFELTEGESVARID

Sequences:

>Translated_334_residues
MTIVDIAKESGYSVTTVSRVLNNRQDVSPAAKETIMKIVEAHNFVPNTNAKRLKQTISRNIYLLVKGTSNMLFANVVEEI
QSIIDRTDYSLSITYLDEDSNLSSVTDRICRERKPLGIIFLGGSREDFSEDTSSFKVPCVIVTTSAENWSMEELSSVSID
DEKAGETIVDYLIEHGHTKIAEIGANLELSQTARLRHNGYLNSLKKHGITPDERYYERARFSYDSAYRAMKKLLEKDIEI
TAVYAISDVMAIGALRAILDKGLRVPEDISITGFDGSTLAEYYNPKIVSIRQPHKDMAARSVELLFNMIDLHKGSCHEII
PFELTEGESVARID
>Mature_333_residues
TIVDIAKESGYSVTTVSRVLNNRQDVSPAAKETIMKIVEAHNFVPNTNAKRLKQTISRNIYLLVKGTSNMLFANVVEEIQ
SIIDRTDYSLSITYLDEDSNLSSVTDRICRERKPLGIIFLGGSREDFSEDTSSFKVPCVIVTTSAENWSMEELSSVSIDD
EKAGETIVDYLIEHGHTKIAEIGANLELSQTARLRHNGYLNSLKKHGITPDERYYERARFSYDSAYRAMKKLLEKDIEIT
AVYAISDVMAIGALRAILDKGLRVPEDISITGFDGSTLAEYYNPKIVSIRQPHKDMAARSVELLFNMIDLHKGSCHEIIP
FELTEGESVARID

Specific function: Repressor of glucanotransferase gene expression [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=326, Percent_Identity=29.7546012269939, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1790194, Length=310, Percent_Identity=26.7741935483871, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788474, Length=308, Percent_Identity=28.5714285714286, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1787948, Length=316, Percent_Identity=26.5822784810127, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789202, Length=303, Percent_Identity=27.7227722772277, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787580, Length=317, Percent_Identity=27.1293375394322, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1786540, Length=333, Percent_Identity=25.5255255255255, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1789068, Length=318, Percent_Identity=27.9874213836478, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI48994940, Length=319, Percent_Identity=25.3918495297806, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790715, Length=317, Percent_Identity=26.813880126183, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1787906, Length=264, Percent_Identity=24.6212121212121, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1789456, Length=319, Percent_Identity=25.3918495297806, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786268, Length=316, Percent_Identity=22.4683544303797, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790689, Length=292, Percent_Identity=22.2602739726027, Blast_Score=75, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37467; Mature: 37336

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIVDIAKESGYSVTTVSRVLNNRQDVSPAAKETIMKIVEAHNFVPNTNAKRLKQTISRN
CCEEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
IYLLVKGTSNMLFANVVEEIQSIIDRTDYSLSITYLDEDSNLSSVTDRICRERKPLGIIF
EEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEE
LGGSREDFSEDTSSFKVPCVIVTTSAENWSMEELSSVSIDDEKAGETIVDYLIEHGHTKI
ECCCCCCHHCCCCCEECEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCHHH
AEIGANLELSQTARLRHNGYLNSLKKHGITPDERYYERARFSYDSAYRAMKKLLEKDIEI
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCE
TAVYAISDVMAIGALRAILDKGLRVPEDISITGFDGSTLAEYYNPKIVSIRQPHKDMAAR
EEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHCCCEEEEECCCHHHHHHH
SVELLFNMIDLHKGSCHEIIPFELTEGESVARID
HHHHHHHHHHHCCCCCCCCCCEEECCCCCEECCC
>Mature Secondary Structure 
TIVDIAKESGYSVTTVSRVLNNRQDVSPAAKETIMKIVEAHNFVPNTNAKRLKQTISRN
CEEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCC
IYLLVKGTSNMLFANVVEEIQSIIDRTDYSLSITYLDEDSNLSSVTDRICRERKPLGIIF
EEEEEECCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHHCCCCEEEEE
LGGSREDFSEDTSSFKVPCVIVTTSAENWSMEELSSVSIDDEKAGETIVDYLIEHGHTKI
ECCCCCCHHCCCCCEECEEEEEEECCCCCCHHHHHCCCCCCHHHHHHHHHHHHHCCCHHH
AEIGANLELSQTARLRHNGYLNSLKKHGITPDERYYERARFSYDSAYRAMKKLLEKDIEI
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCE
TAVYAISDVMAIGALRAILDKGLRVPEDISITGFDGSTLAEYYNPKIVSIRQPHKDMAAR
EEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCHHHHHCCCEEEEECCCHHHHHHH
SVELLFNMIDLHKGSCHEIIPFELTEGESVARID
HHHHHHHHHHHCCCCCCCCCCEEECCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA