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The map label for this gene is cisA [H]

Identifier: 238922591

GI number: 238922591

Start: 159854

End: 161584

Strand: Direct

Name: cisA [H]

Synonym: EUBREC_0165

Alternate gene names: 238922591

Gene position: 159854-161584 (Clockwise)

Preceding gene: 238922590

Following gene: 238922592

Centisome position: 4.63

GC content: 41.77

Gene sequence:

>1731_bases
ATGGAGGTAGCGCAGATGGAAGAAAAAATAGATATTACAGATAAAACAATTGAAATAGATACAGATAAAGGGAGTGCCAT
AAAAGTAACCATGTCATATGGTGAACAATCAACGCTAGAGGAGTTGTTGATAGCATATCTGGAGCAGATAGCAATATATT
TGAGATTATCAAAGGAAGATGAATTTGTAAAAGATGAGAGCAACAGTATTACCAATCAGCGTGCTTTTATCCGTGGATTT
ATTAATAAAAATAAGGAACTTCGCAAAATGAGTGTGATGGAGTTTGTGGATGATGGCTATTCAGGTAAAAATATGGACCG
CCCGGATATGCAGAGAATGCTGGACCTTGTGAAAAGAAAGCAGATTTCATGCGTTATTGTAAAGGATTTCTCCAGATTTT
CCAGAGATCATATCGAGCAGGGAAAATATATTGAACAGATATTTCCTTTTATGGGTGTGCGATTTATTGCTATAAACGAT
AATTATGACAGCGCAGATTATGTGGGTGGTATTGGTGAGATTGATGTTGCATTTAAGGGAATCATGTATGATTTCTTCAG
TGAGGAGCAGTCTTCCAAAGTATCATTGACACTTGATACAAAGCGTGGCAATGGTAAGTACATAGCTACCTATGCTCCTT
ATGGCTATGTGAAAAGTCCGGAGGACAAGCATAAGCTGGTTGTGGATGAGTTTGCCAGTCAGATTGTAAAGCGCATTTTC
AAAGAGTTTCTGTCTGGAAAATCTATGTACAAAATTTCAGAAGGACTGAACCGGGATGGAATAGATACGCCGGGCGTGTA
TATTGCCATGCAGACAGAAAGTGAAAAGCAACTTGCCAGATATCGTGAGAAAAAGCCTCTCTGGAATAATGTTGCAATAG
GAAGAATCCTCGAAAATGAGCAATATACCGGCACGATGATTTACAGCCGCTTCAAGATTGAGAATGTTGGCGATAAACAT
GCAAAAGCACTTCCAAAGGATGAATGGAAGCGTGTGGAAAATTGTCACGAGGCAATTATCAGCAAGGAGGATTTTGAAAA
AGCCGCTGCCATGCGAAAAGGAAATACATGTGCCAGTGCCAAAAGAAAGCATGAAACACATTGCCTGACCGGCAAGATGA
TCTGTGGAAACTGTGGGCATCGCCTGTCCCATACTTATGCCGGTCGACCGAAGTATTATTGTGCAAATCATTATCTGGAT
AAGACTGATGGAAAATGCAATATCAGCGTGTTGGATGCCTATATGGAAAGTGTTGTGAAGAAAGCACTTCAGATGATGAT
TGATGTGTTGGTGGATTCCAGAAAGGTTGTGGATATGCAACGGGAGAAACAGGCAGAACGATTAAAGCAGGCAGAAAAGC
ATCTTTCAGATATGGAGCATAGCCGTGAACTGATCGAAAAGAACCTGCGTGAAGCTTATGAAAGTTACAAGCTTGGCATG
ACGGATAAGGAAACATATCTGGAACAGCGTAAGATATATGAGCAGATGCTTGAGCGCCTGCGGGAGAATATCGAAAAGCA
GAGGGCAGCAGTCACCAAGATGGCAGATGTTGATGTGCCGGAAGTGGCAGGTCTGGAGATGTTGGAAGGGCAGCTGAAGC
TGACGGGACTTAACAGGGAAATGGTGGATGCTTTTGTGGAGGAGATTGTTGTGTATGCAAAGGACAGGGTGGAGATAAAG
TGGAAGTTTAAGGATGAGTTTTGGGAGACAGAAAAGGCTCGAAAGCCTTGA

Upstream 100 bases:

>100_bases
TCATAGGACGTTAAAAGAAGTCCAGAACAGAATTAGTGATAACCAAAATCGTTATCCATAGTTTATGCATTTTCGAATGA
GCTATGGATAGCGTTTTTTT

Downstream 100 bases:

>100_bases
TAATACTGAATATTCGGTGGAGATTAGTGAGAGGAGGTGGTATAATTGGAATGGGAGCGAAAAGTCAAAACAAATATATT
GTCAAGAAGGAAAAGAGGTG

Product: cassette chromosome recombinase B

Products: NA

Alternate protein names: Stage IV sporulation protein CA [H]

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MEVAQMEEKIDITDKTIEIDTDKGSAIKVTMSYGEQSTLEELLIAYLEQIAIYLRLSKEDEFVKDESNSITNQRAFIRGF
INKNKELRKMSVMEFVDDGYSGKNMDRPDMQRMLDLVKRKQISCVIVKDFSRFSRDHIEQGKYIEQIFPFMGVRFIAIND
NYDSADYVGGIGEIDVAFKGIMYDFFSEEQSSKVSLTLDTKRGNGKYIATYAPYGYVKSPEDKHKLVVDEFASQIVKRIF
KEFLSGKSMYKISEGLNRDGIDTPGVYIAMQTESEKQLARYREKKPLWNNVAIGRILENEQYTGTMIYSRFKIENVGDKH
AKALPKDEWKRVENCHEAIISKEDFEKAAAMRKGNTCASAKRKHETHCLTGKMICGNCGHRLSHTYAGRPKYYCANHYLD
KTDGKCNISVLDAYMESVVKKALQMMIDVLVDSRKVVDMQREKQAERLKQAEKHLSDMEHSRELIEKNLREAYESYKLGM
TDKETYLEQRKIYEQMLERLRENIEKQRAAVTKMADVDVPEVAGLEMLEGQLKLTGLNREMVDAFVEEIVVYAKDRVEIK
WKFKDEFWETEKARKP

Sequences:

>Translated_576_residues
MEVAQMEEKIDITDKTIEIDTDKGSAIKVTMSYGEQSTLEELLIAYLEQIAIYLRLSKEDEFVKDESNSITNQRAFIRGF
INKNKELRKMSVMEFVDDGYSGKNMDRPDMQRMLDLVKRKQISCVIVKDFSRFSRDHIEQGKYIEQIFPFMGVRFIAIND
NYDSADYVGGIGEIDVAFKGIMYDFFSEEQSSKVSLTLDTKRGNGKYIATYAPYGYVKSPEDKHKLVVDEFASQIVKRIF
KEFLSGKSMYKISEGLNRDGIDTPGVYIAMQTESEKQLARYREKKPLWNNVAIGRILENEQYTGTMIYSRFKIENVGDKH
AKALPKDEWKRVENCHEAIISKEDFEKAAAMRKGNTCASAKRKHETHCLTGKMICGNCGHRLSHTYAGRPKYYCANHYLD
KTDGKCNISVLDAYMESVVKKALQMMIDVLVDSRKVVDMQREKQAERLKQAEKHLSDMEHSRELIEKNLREAYESYKLGM
TDKETYLEQRKIYEQMLERLRENIEKQRAAVTKMADVDVPEVAGLEMLEGQLKLTGLNREMVDAFVEEIVVYAKDRVEIK
WKFKDEFWETEKARKP
>Mature_576_residues
MEVAQMEEKIDITDKTIEIDTDKGSAIKVTMSYGEQSTLEELLIAYLEQIAIYLRLSKEDEFVKDESNSITNQRAFIRGF
INKNKELRKMSVMEFVDDGYSGKNMDRPDMQRMLDLVKRKQISCVIVKDFSRFSRDHIEQGKYIEQIFPFMGVRFIAIND
NYDSADYVGGIGEIDVAFKGIMYDFFSEEQSSKVSLTLDTKRGNGKYIATYAPYGYVKSPEDKHKLVVDEFASQIVKRIF
KEFLSGKSMYKISEGLNRDGIDTPGVYIAMQTESEKQLARYREKKPLWNNVAIGRILENEQYTGTMIYSRFKIENVGDKH
AKALPKDEWKRVENCHEAIISKEDFEKAAAMRKGNTCASAKRKHETHCLTGKMICGNCGHRLSHTYAGRPKYYCANHYLD
KTDGKCNISVLDAYMESVVKKALQMMIDVLVDSRKVVDMQREKQAERLKQAEKHLSDMEHSRELIEKNLREAYESYKLGM
TDKETYLEQRKIYEQMLERLRENIEKQRAAVTKMADVDVPEVAGLEMLEGQLKLTGLNREMVDAFVEEIVVYAKDRVEIK
WKFKDEFWETEKARKP

Specific function: Putative site-specific recombinase having a very important role in sporulation. It probably plays a role in the recombination of spoIIIC and spoIVCB to form sigma K factor [H]

COG id: COG1961

COG function: function code L; Site-specific recombinases, DNA invertase Pin homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 recombinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011109
- InterPro:   IPR006118
- InterPro:   IPR006119 [H]

Pfam domain/function: PF07508 Recombinase; PF00239 Resolvase [H]

EC number: NA

Molecular weight: Translated: 66854; Mature: 66854

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVAQMEEKIDITDKTIEIDTDKGSAIKVTMSYGEQSTLEELLIAYLEQIAIYLRLSKED
CCHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEECCCC
EFVKDESNSITNQRAFIRGFINKNKELRKMSVMEFVDDGYSGKNMDRPDMQRMLDLVKRK
CHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
QISCVIVKDFSRFSRDHIEQGKYIEQIFPFMGVRFIAINDNYDSADYVGGIGEIDVAFKG
CCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHCEEEEEEECCCCCHHHCCCCCCHHHHHHH
IMYDFFSEEQSSKVSLTLDTKRGNGKYIATYAPYGYVKSPEDKHKLVVDEFASQIVKRIF
HHHHHHCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KEFLSGKSMYKISEGLNRDGIDTPGVYIAMQTESEKQLARYREKKPLWNNVAIGRILENE
HHHHCCCCEEHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHCCCC
QYTGTMIYSRFKIENVGDKHAKALPKDEWKRVENCHEAIISKEDFEKAAAMRKGNTCASA
CCCCEEEEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHH
KRKHETHCLTGKMICGNCGHRLSHTYAGRPKYYCANHYLDKTDGKCNISVLDAYMESVVK
HHHHHHHHCCCCHHCCCCCCHHCCCCCCCCCEEECCCCCCCCCCCEEHHHHHHHHHHHHH
KALQMMIDVLVDSRKVVDMQREKQAERLKQAEKHLSDMEHSRELIEKNLREAYESYKLGM
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TDKETYLEQRKIYEQMLERLRENIEKQRAAVTKMADVDVPEVAGLEMLEGQLKLTGLNRE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEEEECCHH
MVDAFVEEIVVYAKDRVEIKWKFKDEFWETEKARKP
HHHHHHHHHHHHHCCCEEEEEEECHHHHCCHHCCCC
>Mature Secondary Structure
MEVAQMEEKIDITDKTIEIDTDKGSAIKVTMSYGEQSTLEELLIAYLEQIAIYLRLSKED
CCHHHHHHHCCCCCCEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHEECCCC
EFVKDESNSITNQRAFIRGFINKNKELRKMSVMEFVDDGYSGKNMDRPDMQRMLDLVKRK
CHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
QISCVIVKDFSRFSRDHIEQGKYIEQIFPFMGVRFIAINDNYDSADYVGGIGEIDVAFKG
CCCEEEEHHHHHHHHHHHHCCHHHHHHHHHHCEEEEEEECCCCCHHHCCCCCCHHHHHHH
IMYDFFSEEQSSKVSLTLDTKRGNGKYIATYAPYGYVKSPEDKHKLVVDEFASQIVKRIF
HHHHHHCCCCCCEEEEEEECCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KEFLSGKSMYKISEGLNRDGIDTPGVYIAMQTESEKQLARYREKKPLWNNVAIGRILENE
HHHHCCCCEEHHHHCCCCCCCCCCCEEEEEECCCHHHHHHHHHCCCCCCCHHHHHHCCCC
QYTGTMIYSRFKIENVGDKHAKALPKDEWKRVENCHEAIISKEDFEKAAAMRKGNTCASA
CCCCEEEEEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCHHHH
KRKHETHCLTGKMICGNCGHRLSHTYAGRPKYYCANHYLDKTDGKCNISVLDAYMESVVK
HHHHHHHHCCCCHHCCCCCCHHCCCCCCCCCEEECCCCCCCCCCCEEHHHHHHHHHHHHH
KALQMMIDVLVDSRKVVDMQREKQAERLKQAEKHLSDMEHSRELIEKNLREAYESYKLGM
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
TDKETYLEQRKIYEQMLERLRENIEKQRAAVTKMADVDVPEVAGLEMLEGQLKLTGLNRE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCEEEEEECCHH
MVDAFVEEIVVYAKDRVEIKWKFKDEFWETEKARKP
HHHHHHHHHHHHHCCCEEEEEEECHHHHCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2105293; 7704261; 8969508; 9384377 [H]