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The map label for this gene is coaX

Identifier: 238922486

GI number: 238922486

Start: 64283

End: 65065

Strand: Direct

Name: coaX

Synonym: EUBREC_0060

Alternate gene names: 238922486

Gene position: 64283-65065 (Clockwise)

Preceding gene: 238922485

Following gene: 238922487

Centisome position: 1.86

GC content: 45.72

Gene sequence:

>783_bases
ATGATTTTAGCACTGGACGTAGGAAATACAAACATAACATGCGGCGTGTTTGATGGTGACAGGATAAAAGCAAGCTTTAG
AATTACAACTAAAATGCCACGTACATCAGATGAATATGGCATGCTTCTGAGCACTCTGCTTGAAAGAAATCAGGTAGGCA
TGGACGACATACATGATGCAATCATCTGCTCCGTTGTACCGAATATCATGCATTCACTGCAGAATGGCCTAATAAAATAC
TTCAATATCAGGCCGATAATCGTGGAGGCGGGCATCAAAACAGGCATCCGTATCGCCACACCAAATCCGCAGCAAATTGG
CGCAGACCGTATAGTAGACGCCGTAGCTGCATATGAATTATATGGAGGACCTGTTTTGGTCATAGATTTTGGCACAGCAA
CCACCTACGATATGGTCGATGAAAACGGTACCTTCATGGGAGGAATCACAGCACCGGGCATACGTATCTCAGCCAAGGCA
CTCTGGGAGGATGCGGCAAAGCTTCCTGAGATAGAGATTAAAAAGCCTGATAATATCCTCGGAAAGGACACCATCACCAG
CATGCAGGCGGGACTTGTGTATGGACAGATAGGACAGACAGAGTACATCATCAACAAGGTAAAGGAAGAAACAGGCATGT
ACGATGCAAAGGTTGTAGTGACCGGCGGACTCGGCAGAATAATATCCAATGAGACAGAAAACGTGGATGTATACGATCCG
GATCTGACATTAAAGGGCATAAACCTCGTGTATCGCAAGCAGAACCGCAAGGGAGTGAAGTAA

Upstream 100 bases:

>100_bases
GATAAAGCAGTACCGCAACGAGCGAAGAGAGCTGCTCGAGTCGATAGAGACGTATTATCGCATAGTATTTTTGGGAGAAG
GACTCGAGGAGGAATAACAG

Downstream 100 bases:

>100_bases
TAGTATGGATATTCATCAGATACGAAAGCTTCAGATAGGAAGTGTGACACTCCCAAACAACCTGATACTGGGACCTATGG
CAGGCGTGACAGACCTGCCA

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MILALDVGNTNITCGVFDGDRIKASFRITTKMPRTSDEYGMLLSTLLERNQVGMDDIHDAIICSVVPNIMHSLQNGLIKY
FNIRPIIVEAGIKTGIRIATPNPQQIGADRIVDAVAAYELYGGPVLVIDFGTATTYDMVDENGTFMGGITAPGIRISAKA
LWEDAAKLPEIEIKKPDNILGKDTITSMQAGLVYGQIGQTEYIINKVKEETGMYDAKVVVTGGLGRIISNETENVDVYDP
DLTLKGINLVYRKQNRKGVK

Sequences:

>Translated_260_residues
MILALDVGNTNITCGVFDGDRIKASFRITTKMPRTSDEYGMLLSTLLERNQVGMDDIHDAIICSVVPNIMHSLQNGLIKY
FNIRPIIVEAGIKTGIRIATPNPQQIGADRIVDAVAAYELYGGPVLVIDFGTATTYDMVDENGTFMGGITAPGIRISAKA
LWEDAAKLPEIEIKKPDNILGKDTITSMQAGLVYGQIGQTEYIINKVKEETGMYDAKVVVTGGLGRIISNETENVDVYDP
DLTLKGINLVYRKQNRKGVK
>Mature_260_residues
MILALDVGNTNITCGVFDGDRIKASFRITTKMPRTSDEYGMLLSTLLERNQVGMDDIHDAIICSVVPNIMHSLQNGLIKY
FNIRPIIVEAGIKTGIRIATPNPQQIGADRIVDAVAAYELYGGPVLVIDFGTATTYDMVDENGTFMGGITAPGIRISAKA
LWEDAAKLPEIEIKKPDNILGKDTITSMQAGLVYGQIGQTEYIINKVKEETGMYDAKVVVTGGLGRIISNETENVDVYDP
DLTLKGINLVYRKQNRKGVK

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_EUBR3 (C4Z9L7)

Other databases:

- EMBL:   CP001107
- RefSeq:   YP_002935999.1
- GeneID:   7963280
- GenomeReviews:   CP001107_GR
- KEGG:   ere:EUBREC_0060
- ProtClustDB:   CLSK2506072
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28399; Mature: 28399

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: ACT_SITE 109-109 BINDING 132-132 BINDING 184-184

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILALDVGNTNITCGVFDGDRIKASFRITTKMPRTSDEYGMLLSTLLERNQVGMDDIHDA
CEEEEEECCCEEEEEEECCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
IICSVVPNIMHSLQNGLIKYFNIRPIIVEAGIKTGIRIATPNPQQIGADRIVDAVAAYEL
HHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCCEEEECCCHHHCCHHHHHHHHHHHHH
YGGPVLVIDFGTATTYDMVDENGTFMGGITAPGIRISAKALWEDAAKLPEIEIKKPDNIL
CCCCEEEEECCCCCEEEEECCCCCEEECCCCCCEEEEHHHHHHHHHHCCCEEEECCCCCC
GKDTITSMQAGLVYGQIGQTEYIINKVKEETGMYDAKVVVTGGLGRIISNETENVDVYDP
CCHHHHHHHHCEEEECCCCHHHHHHHHHHHCCCEEEEEEEECCCCHHHCCCCCCCEEECC
DLTLKGINLVYRKQNRKGVK
CEEEECCEEEEEECCCCCCC
>Mature Secondary Structure
MILALDVGNTNITCGVFDGDRIKASFRITTKMPRTSDEYGMLLSTLLERNQVGMDDIHDA
CEEEEEECCCEEEEEEECCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
IICSVVPNIMHSLQNGLIKYFNIRPIIVEAGIKTGIRIATPNPQQIGADRIVDAVAAYEL
HHHHHHHHHHHHHHHCCEEEECCCEEEEECCCCCCEEEECCCHHHCCHHHHHHHHHHHHH
YGGPVLVIDFGTATTYDMVDENGTFMGGITAPGIRISAKALWEDAAKLPEIEIKKPDNIL
CCCCEEEEECCCCCEEEEECCCCCEEECCCCCCEEEEHHHHHHHHHHCCCEEEECCCCCC
GKDTITSMQAGLVYGQIGQTEYIINKVKEETGMYDAKVVVTGGLGRIISNETENVDVYDP
CCHHHHHHHHCEEEECCCCHHHHHHHHHHHCCCEEEEEEEECCCCHHHCCCCCCCEEECC
DLTLKGINLVYRKQNRKGVK
CEEEECCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA