Click here to switch to the map view.

The map label for this gene is arcB [H]

Identifier: 238922483

GI number: 238922483

Start: 61928

End: 62917

Strand: Direct

Name: arcB [H]

Synonym: EUBREC_0057

Alternate gene names: 238922483

Gene position: 61928-62917 (Clockwise)

Preceding gene: 238922482

Following gene: 238922484

Centisome position: 1.8

GC content: 46.67

Gene sequence:

>990_bases
ATGCAGTTAAAGGGACGAAACTTTTTAAAACTTATGGATTACACTCCGGAAGAGATTACTTATCTGATTGACCTCTCACA
GGAGCTGAAGGAAAAGAAGAAAAAAGGCATCAGACATGATGAACTCACAGGCAAGAATATAGCGCTGATTTTTGAAAAGA
CCAGTACCAGAACTCGCTGCTCTTTTGAGGTAGCGGCACATGACCTTGGAATGCATGTCACATACCTTGACCCGAGCGGT
TCACAGATAGGTAAAAAGGAGAGCATCGCCGATACAGCGCGCGTGCTCGGCAGAATGTTTGACGGAATCGAGTACCGTGG
ATACGGACAGGAAATCGTGGAGGAGCTGGCTAAATACGCAGGCGTACCGGTATGGAACGGCCTGACAAATGAGTTCCACC
CGACACAGATGATAGCAGATATGCTTACAATCCGTGAGCACCTCGGCAGACTGGGGGGCGTGAAATTTGTATACATGGGA
GATGCAAGATACAACATGGGCAATTCACTCATGGTCACATGTGCAAAGCTTGGCATGGACTTCGTGGCATGCACAAACAA
GAAATATTTCCCAAATGATGAGCTTGTAAAATACTGTAAGGACGTTGCAGAAACAACCGGCGCATCAATCACACTCACAG
AGGATGTGGCAGAGGGCACAAAGGATGCAGATGTCATCTACACAGATGTGTGGGTATCAATGGGCGAGCCGGAAGAGGTA
TGGGCAGAGCGAATTAACGACTTAAAGCCATATCAGGTAAATGCAAAAGCATTTGAAAATGCAAAGGATAGCGCAATCTT
TATGCACTGTCTGCCTGCATTCCATGATTTAAAGACCACAATCGGCAAGCAGGTCTATGAGAAGTTTGGACTGAGTGAGC
TTGAGGTGACAGACGAGGTATTTGAGTCAGAGCGTTCAGTGGTATTTGATGAGGCAGAGAACCGTATGCACTCAATCAAG
GCTATCATGCGTGCAACACTTGCGGACTAG

Upstream 100 bases:

>100_bases
CAAAATAGAGTAAAATGACATCATTATAGCAACCTACAGATATAAATTATAGCAACCTGCATCTATAAACGATGCAAATA
AAACCCAGGAGGCAAGAGCA

Downstream 100 bases:

>100_bases
TACGGCAAGCAATGACCGCAACAAAAGATTGACGGAAAGCTAAGGAATAAAGTATGAAGGAAGAAATACTTAGACTTCTA
CGCAGCGCTGACGGCTATAT

Product: ornithine carbamoyltransferase

Products: NA

Alternate protein names: OTCase [H]

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MQLKGRNFLKLMDYTPEEITYLIDLSQELKEKKKKGIRHDELTGKNIALIFEKTSTRTRCSFEVAAHDLGMHVTYLDPSG
SQIGKKESIADTARVLGRMFDGIEYRGYGQEIVEELAKYAGVPVWNGLTNEFHPTQMIADMLTIREHLGRLGGVKFVYMG
DARYNMGNSLMVTCAKLGMDFVACTNKKYFPNDELVKYCKDVAETTGASITLTEDVAEGTKDADVIYTDVWVSMGEPEEV
WAERINDLKPYQVNAKAFENAKDSAIFMHCLPAFHDLKTTIGKQVYEKFGLSELEVTDEVFESERSVVFDEAENRMHSIK
AIMRATLAD

Sequences:

>Translated_329_residues
MQLKGRNFLKLMDYTPEEITYLIDLSQELKEKKKKGIRHDELTGKNIALIFEKTSTRTRCSFEVAAHDLGMHVTYLDPSG
SQIGKKESIADTARVLGRMFDGIEYRGYGQEIVEELAKYAGVPVWNGLTNEFHPTQMIADMLTIREHLGRLGGVKFVYMG
DARYNMGNSLMVTCAKLGMDFVACTNKKYFPNDELVKYCKDVAETTGASITLTEDVAEGTKDADVIYTDVWVSMGEPEEV
WAERINDLKPYQVNAKAFENAKDSAIFMHCLPAFHDLKTTIGKQVYEKFGLSELEVTDEVFESERSVVFDEAENRMHSIK
AIMRATLAD
>Mature_329_residues
MQLKGRNFLKLMDYTPEEITYLIDLSQELKEKKKKGIRHDELTGKNIALIFEKTSTRTRCSFEVAAHDLGMHVTYLDPSG
SQIGKKESIADTARVLGRMFDGIEYRGYGQEIVEELAKYAGVPVWNGLTNEFHPTQMIADMLTIREHLGRLGGVKFVYMG
DARYNMGNSLMVTCAKLGMDFVACTNKKYFPNDELVKYCKDVAETTGASITLTEDVAEGTKDADVIYTDVWVSMGEPEEV
WAERINDLKPYQVNAKAFENAKDSAIFMHCLPAFHDLKTTIGKQVYEKFGLSELEVTDEVFESERSVVFDEAENRMHSIK
AIMRATLAD

Specific function: Arginine biosynthesis; sixth step. [C]

COG id: COG0078

COG function: function code E; Ornithine carbamoyltransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATCase/OTCase family [H]

Homologues:

Organism=Homo sapiens, GI38788445, Length=330, Percent_Identity=40, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI18105007, Length=337, Percent_Identity=24.9258160237389, Blast_Score=93, Evalue=3e-19,
Organism=Escherichia coli, GI1790703, Length=327, Percent_Identity=61.7737003058104, Blast_Score=409, Evalue=1e-115,
Organism=Escherichia coli, GI1786469, Length=328, Percent_Identity=61.5853658536585, Blast_Score=406, Evalue=1e-115,
Organism=Escherichia coli, GI48994908, Length=370, Percent_Identity=26.7567567567568, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI2367364, Length=291, Percent_Identity=29.553264604811, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI193204318, Length=234, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6322373, Length=328, Percent_Identity=32.9268292682927, Blast_Score=163, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6322331, Length=282, Percent_Identity=30.4964539007092, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24642586, Length=291, Percent_Identity=26.8041237113402, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2066 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006132
- InterPro:   IPR006130
- InterPro:   IPR006131
- InterPro:   IPR002292 [H]

Pfam domain/function: PF00185 OTCace; PF02729 OTCace_N [H]

EC number: =2.1.3.3 [H]

Molecular weight: Translated: 37198; Mature: 37198

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: PS00097 CARBAMOYLTRANSFERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLKGRNFLKLMDYTPEEITYLIDLSQELKEKKKKGIRHDELTGKNIALIFEKTSTRTRC
CCCCCCCHHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEE
SFEVAAHDLGMHVTYLDPSGSQIGKKESIADTARVLGRMFDGIEYRGYGQEIVEELAKYA
EHEEHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
GVPVWNGLTNEFHPTQMIADMLTIREHLGRLGGVKFVYMGDARYNMGNSLMVTCAKLGMD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCH
FVACTNKKYFPNDELVKYCKDVAETTGASITLTEDVAEGTKDADVIYTDVWVSMGEPEEV
HEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCEEEEEEEEECCCHHHH
WAERINDLKPYQVNAKAFENAKDSAIFMHCLPAFHDLKTTIGKQVYEKFGLSELEVTDEV
HHHHHCCCCCCEECHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FESERSVVFDEAENRMHSIKAIMRATLAD
HHCCCCEEHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLKGRNFLKLMDYTPEEITYLIDLSQELKEKKKKGIRHDELTGKNIALIFEKTSTRTRC
CCCCCCCHHEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCEE
SFEVAAHDLGMHVTYLDPSGSQIGKKESIADTARVLGRMFDGIEYRGYGQEIVEELAKYA
EHEEHHHHCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHC
GVPVWNGLTNEFHPTQMIADMLTIREHLGRLGGVKFVYMGDARYNMGNSLMVTCAKLGMD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCH
FVACTNKKYFPNDELVKYCKDVAETTGASITLTEDVAEGTKDADVIYTDVWVSMGEPEEV
HEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEHHHHCCCCCCCEEEEEEEEECCCHHHH
WAERINDLKPYQVNAKAFENAKDSAIFMHCLPAFHDLKTTIGKQVYEKFGLSELEVTDEV
HHHHHCCCCCCEECHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
FESERSVVFDEAENRMHSIKAIMRATLAD
HHCCCCEEHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA